LOCUS       XM_039090130            8715 bp    mRNA    linear   ROD 22-FEB-2024
DEFINITION  PREDICTED: Rattus norvegicus SET domain containing 1B, histone
            lysine methyltransferase (Setd1b), transcript variant X4, mRNA.
ACCESSION   XM_039090130
VERSION     XM_039090130.1
DBLINK      BioProject: PRJNA1074393
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086030) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8715
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     gene            1..8715
                     /gene="Setd1b"
                     /note="SET domain containing 1B, histone lysine
                     methyltransferase; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 5 ESTs, 83 long SRA
                     reads, 5 Proteins"
                     /db_xref="GeneID:100359816"
                     /db_xref="RGD:2323325"
     CDS             286..6261
                     /gene="Setd1b"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase SETD1B
                     isoform X2"
                     /protein_id="XP_038946058.1"
                     /db_xref="GeneID:100359816"
                     /db_xref="RGD:2323325"
                     /translation="MENSHPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHH
                     KLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPK
                     QVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKEAV
                     QHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVGELDAISPIVSETLQ
                     LSDALKRLKDGNLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPITP
                     RLGTPFSQDSSYSSRQPTPSYLFSQDPAATFKARRHESKFTDAYNRRHEHHYVHNSAV
                     AAAVAGATAPFRGSSDLSFGTVGGSGGGTPFKTQSQDSTTYAHTPPPAQTATASGFKS
                     AFSPYQTPAPPFPPPPEEPTATAAFGTRDSGEFRRAPAPPPLPPSEPPAKEKPGTPPG
                     PPPPDNNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQR
                     TKLPFLREQDSDTEIQMEGSPISSSSSQLSPLTHFGTNSQPGFRGPSPPSSRPSSTGL
                     EDISPTPLPDSDEDDDLGLGLGPRPPPEPGPPDPMGLLGQTAEVNLDLAGDRTPTSER
                     MDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAGAVAAPNVLAPNLPLPPPP
                     GFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPIL
                     PPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQMLSRLMTGQGTCPYPPFMAA
                     AAAAASAGLQFVNLPPYRSPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYIPRQEDPHK
                     ATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEH
                     KDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTAS
                     SGDQKRLRPSTSVDEEDEESERERDRDMADAPCELAKRDPKSVGVRRRPGRPLELDSG
                     GEEDEKESLSVSSSSSASSSSGSSTTSPSSSASDKEEEERESTEEEEEEEEAEEEEED
                     EERPRSHISSPSSSSSSDKDDDDDDDSDDQIDSDIDDQGTALSVASEKDNVDSEEEEI
                     ERVTTSKAPAVSSSSSSSSSSSESSGSSEFDSSSESSSSSSSSEDEDEMTVPGEDEEE
                     EEEEEEKETAMATATVVAMAEESMPPVGGQDFEQDRAEVPLGPRGPLRESLCTEEEVD
                     IEAEDEVPEMQAPVPEESPLPMGAQELSPEPPEEPSPNTQGDMLLSPELPARETEAQP
                     PSLPEHGPESDLEVEPEPPPMLSLPLQPPLLPPRHPRPPSPPPEPETPEPPKPPVPLE
                     PPPEDQPPRTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYP
                     SPSPGLSSGGLPRTPGRDFTFTPTFPEPSGPLLLPVCPLPTGRRDERAGPLASPVLLE
                     TGLPLPLPLPLPLPLALPVPVLRAQPRPPPQLPPLLPATLAPCPTPIKRKPGRPRRSP
                     PSMLSLDGPLVRPPPGPALGRDLLLLPGQPQAPIFPSAHDPRAVTLDFRNTGIPAPPP
                     PLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRRDEVTEEYMDLAKVRGPWR
                     RPPKKRHEDLVAQSASPEPSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTY
                     ERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKREDGIREHVTGCARSEGFYTIDKKD
                     KLRYLNSSRASTDEPPMDTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLL
                     KFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYED
                     EGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHI
                     NVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN"
     polyA_site      8715
                     /gene="Setd1b"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gctcgggtcg ggctccttag cggtgtattg tgggatgtgc ggctactggg agccgagcct
       61 ccgccgccag ccgcctcccg ggcagcagca gcagcagcgg cggcagcagc ggcggcagca
      121 gcagcaaggg cagcggcagc tcggggcccg gcagccgcta aggcggcgtc ccccccatcc
      181 cggcccccgg tccacccgcc ccggcctcgg ctcccgcggg ggacaccatg tactggctgg
      241 cggcgcaggg aggccggcgc ccggcgggga tgttgggtta acggcatgga gaacagtcac
      301 ccccaccacc accaccagca gcccccgccg cagcccggcc cttcgggcga gaggaggaac
      361 caccattgga gaagttacaa gttgatgatt gacccggctc tgaaaaaggg gcaccataaa
      421 ctgtaccgct acgatgggca gcatttcagc ctggcgatgt ccagcaaccg cccggtggaa
      481 atcgtggaag atccccgggt ggtcggcatc tggaccaaaa acaaggagct ggagctgtcg
      541 gtgcccaaat tcaagatcga tgagttctac gtgggccctg tgcctcccaa gcaggtgaca
      601 tttgccaagc tgaatgacaa catccgcgaa aacttcctaa gggacatgtg caaaaagtat
      661 ggggaagttg aggaggtgga gattttgtat aacccgaaga ccaagaaaca cctgggcatc
      721 gccaaggtag tctttgccac ggtcaggggc gccaaggagg cagtccaaca cttgcatagc
      781 acttctgtca tgggtaacat catccacgtg gagctggaca ccaaagggga aactcgcatg
      841 cgcttctatg aactgctggt caccggccgg tacacccctc agaccctccc agtgggtgag
      901 ctggatgcta tttctccaat tgtgagcgag accctgcagc tctcggacgc tctgaagcgg
      961 ctcaaagatg gtaacctgtc cgcaggctgt ggctctggct cctcctcggt cacccccaat
     1021 agtggcggga cccccttctc ccaggataca gcctactcca gctgccgtct ggacacaccc
     1081 aactcctacg gacaaggcac cccgatcacg ccccgcctgg gcaccccttt ctcccaagat
     1141 tccagctatt ccagtcgtca gcccacaccc tcctacctct tcagccagga ccccgcagca
     1201 actttcaagg ccaggcggca cgagagcaag ttcacagatg cctataaccg ccgtcatgaa
     1261 caccattatg tccacaattc cgcggtggca gctgcggtgg caggagccac ggctcctttc
     1321 cgaggctcct cagacctctc ttttgggaca gttggcggca gtggcggcgg cactcccttc
     1381 aagactcaat cccaggattc caccacatat gcccatactc cacctcctgc ccaaacagcc
     1441 actgcttccg gattcaaatc agccttttct ccataccaga ctccagcacc cccattcccg
     1501 ccaccccccg aggagcccac tgccacagca gccttcggga cccgcgacag tggggagttc
     1561 cggagggcac ccgcgccccc acccctgccg ccctctgagc ctccagccaa ggagaagccg
     1621 ggcacacctc ccggtccccc accccctgac aacaacagca tggagctggg tggtaggcct
     1681 acctttggct ggagtcctga gccctgtgac agccctggca ctcctactct ggagtcttct
     1741 ccagcgggac cagagaagcc ccatgacagc ctggactccc gcattgagat gctgttgaag
     1801 gaacaacgca ccaagctgcc cttcctgcgg gagcaggact cagacaccga gatccagatg
     1861 gaaggcagcc ccatctcctc ctcctcctcc cagctctccc cactcaccca ctttggcact
     1921 aactcccagc ctggcttccg tggcccctcg ccaccctcct cacgcccctc tagcacgggc
     1981 ctagaggaca tcagccctac accactgcct gattccgacg aggatgatga cctgggcctg
     2041 ggcctcgggc ctcggccccc acctgagcca ggccccccag accctatggg tcttctaggc
     2101 cagacagctg aggtgaattt ggacctggca ggagacagga ccccgacctc agagcggatg
     2161 gatgagggcc agcagtcctc tggagaggac atggaaatct cagacgatga gatgccctca
     2221 gcccccatca ccagcgctga ctgccccaag cccatggtgg tgaccccagg ggcaggggct
     2281 gtggcagccc ctaatgtgct tgctccaaac ctgcccctgc ccccaccccc tggcttccct
     2341 ccgttacccc caccacctcc cccaccccca ccgcaacctg gcttccccat gcccccacct
     2401 ttgccgccgc caccaccacc accaccacca ccagcccatc ctgcagtgac agtccccccg
     2461 ccacccttgc cagcgccccc gggtgtccca cccccaccca tccttccacc actgccgccc
     2521 ttcccgccag gactgtttcc tgtgatgcag gtggacatga gccatgtgct gggtgggcag
     2581 tggggcggca tgcccatgtc cttccagatg caaacacaga tgttaagccg gctcatgaca
     2641 ggccagggta cttgccccta cccacccttc atggccgctg ccgccgctgc cgcttctgct
     2701 gggctacagt ttgtcaactt gcccccctac cggagcccgt tctccctgag caacagtggc
     2761 ccaggacgtg gacagcactg gccgcccctg cccaagtttg acccctctgt gccaccacca
     2821 ggctacatac cgcgtcagga ggatccgcac aaggccacag tggatggggt cctgctagta
     2881 gtgctcaagg aactgaaggc cattatgaag cgggatctca accgcaagat ggtggaggtg
     2941 gtggccttcc gggcctttga cgaatggtgg gacaaaaagg agcggatggc caaggcctca
     3001 ctgacccccg tgaagtctgg tgagcacaag gatgaggaca ggccaaagcc caaagaccga
     3061 atcgcctcct gcctgctgga atcatggggc aagggcgagg gcctgggtta cgagggccta
     3121 ggcctgggca ttggactacg gggcgccatt cgcctgccct ccttcaaggt caagaggaag
     3181 gagccaccgg acacagcctc ttctggcgac cagaagcggc tgcggccttc aacctctgtg
     3241 gatgaggaag atgaagagtc ggaacgggag cgtgaccggg acatggctga tgccccgtgc
     3301 gaactcgcca agcgggaccc caaaagtgtg ggtgtgcgac gccggccagg acggcccctg
     3361 gagctggaca gcggtgggga ggaggacgag aaggagtcct tgtccgtgtc ctcatcttcc
     3421 tcagcatcct catcctctgg atcttccaca acctcaccct catcctccgc ctcggacaag
     3481 gaagaggagg aacgagaaag cactgaggag gaggaagagg aagaggaagc agaggaagag
     3541 gaggaggatg aagagcgccc caggagccac atatcctccc cctcatcctc atccagctct
     3601 gataaggatg atgatgatga tgatgacagt gatgaccaga ttgattctga catcgacgat
     3661 cagggtacag ccctgtcggt ggccagtgag aaggacaatg ttgattctga ggaagaggag
     3721 atagagagag tcaccacctc caaggccccg gctgtgtcat cgtcgtcatc gtcgtcgtcg
     3781 tcctccagtg aaagttctgg atcttctgaa ttcgattcca gttctgagtc ctcatcctca
     3841 tcttcatcct cggaggatga agacgagatg actgtacctg gggaagacga ggaagaggag
     3901 gaggaggagg aggagaaaga gaccgcaatg gctacagcga cggtagtggc gatggccgag
     3961 gagagcatgc ctccagtggg cggccaggac tttgagcagg atagggcaga agtgcctctg
     4021 ggcccaagag gccccctgag ggagtccttg tgcacagaag aggaagtgga cattgaggcc
     4081 gaggacgaag tccccgagat gcaggctcct gtgccggaag agtctccatt gcccatgggt
     4141 gctcaggaac tgagccccga gcccccagaa gagccaagcc caaacacaca aggggacatg
     4201 ttgctctctc cagaactccc tgccagggag acagaagctc aacccccatc actccctgaa
     4261 catggtccag agtcagacct ggaagtggag cccgagcccc ctccgatgct ctccttaccc
     4321 ttgcagccac cattgctacc ccctcgacat ccccggccac ccagcccacc acctgagccc
     4381 gagaccccag agccccccaa acctcctgtc cccctggagc ctcctcccga agaccagcct
     4441 ccacgtaccc cgggcctctg tggcagtctg gccaagtcac agagcacgga gacagtgccg
     4501 gccaccccgg gcggggagcc tccactgtca gggggcagca gtggcctgtc actgagctcc
     4561 ccgcaggtgc ctggcagccc gttctcatac ccttccccgt cccctggctt gagcagtggg
     4621 ggccttccac ggacacctgg tcgggacttc accttcacac ctaccttccc tgagcccagt
     4681 gggcccttgc ttctgcctgt ctgccccctc cccactggtc gacgagatga gcgcgctggc
     4741 cccctggcct ccccagtgct cctggaaact ggcctgcccc tcccccttcc cctgcctctg
     4801 cccttacctc tggcattgcc tgtccctgtc ctgagggccc agcctcggcc gcctccccag
     4861 ctgcctccct tactgcctgc taccctagct ccctgcccaa cccccatcaa gaggaagcca
     4921 ggccggcccc ggcgatcccc accatctatg ctgtccttgg atggaccttt ggtccggcca
     4981 ccaccagggc ctgcccttgg gagggacctt ctgctcctgc caggccaacc acaggccccc
     5041 attttcccca gtgcacatga tccccgggcc gtgaccttgg acttccggaa cacggggatc
     5101 ccagcccccc caccgcccct cccaccccag cctcctccac ccccgccacc accacctgtt
     5161 gagcccacca agctgccctt caaggagctg gacaaccagt ggccctctga agctattccc
     5221 ccaggacctc gccgagatga ggtcactgaa gagtacatgg acctggccaa ggtgcgggga
     5281 ccatggcgac ggccacctaa gaagcgccac gaagacctgg tggcccaatc agcctcaccc
     5341 gaaccctcac caccccagcc tctcttccgg ccccgctcag agtttgagga gatgaccatc
     5401 ctgtatgaca tctggaatgg tggcattgat gaggaggaca tccgcttcct atgcgtcacc
     5461 tacgagcgcc tgttgcagca ggacaatggc atggactggc tgaatgacac actctgggtc
     5521 taccatccct ccaccagcct ttcctcagcc aagaaaaaga aacgggagga cggtatccgt
     5581 gagcacgtga caggctgcgc ccgaagcgag ggcttctaca ccatcgacaa gaaagacaag
     5641 ctgagatacc tcaatagcag ccgtgccagc acagatgagc cccccatgga tacccagggt
     5701 atgagcatcc cagcacagcc ccatgcctct acccgggcag gctcagagcg gcggtctgag
     5761 cagcggcgcc tcctgtcctc cttcaccggc agctgtgaca gtgacctgct caagttcaac
     5821 cagctcaagt ttcggaagaa aaagctcaag ttctgtaaga gccacattca cgactggggc
     5881 ctgtttgcca tggagcccat cgctgccgat gagatggtca ttgagtacgt gggtcagaac
     5941 atccgccagg tgattgcaga catgagggag aaacggtacg aggacgaagg catcggtagc
     6001 agctacatgt tcagggtaga ccacgacacc atcatcgacg ccaccaagtg cggcaacttt
     6061 gcgcggttca ttaatcacag ctgcaatccc aactgctatg ccaaggtgat cacggtggag
     6121 tcccagaaga aaattgtcat ctactccaag cagcacatca atgtcaacga ggagatcaca
     6181 tatgactata agttccccat tgaggacgtc aagataccct gcctctgtgg ctccgagaac
     6241 tgccggggga ccctcaacta gtccctgggt gccaaaggcc aaggatgtca gccgtagccc
     6301 aggaggaccc tcgccctggg tcaggctcca cccccaccca tttcaggtgc tgtcctttcc
     6361 cccagcagcc gctctagggc ctggcgcccc ccaacactat cccaggaccc gcccgcagcc
     6421 ccggccccgc agcgggaaag ggcttctctc tctccacccg cgtctttctt tccgttttat
     6481 agatgctctt tgcaggcgtt gtgtcctggt gtatttggct ttccaatccc tcatccatct
     6541 tccctccctg tctcctgcct cagtttcctc ccgtgaatgc tgctctgtgg tgttgtctcc
     6601 tcttttattt tcttccttgt ccgaagaaaa gacattttaa ccgttgaaaa tgtgaaggca
     6661 gaatcagagg aggagccacg tgggggcccg gaggcctcag tggaactgtg tgggcccagg
     6721 gtccaggctg accctgggct aggtgctgca ggaggagggg gctccagcgg cctcgatctc
     6781 agaacactac atacccgaaa ggcccctccc cgcctgtgga tgcagtgatc agaccccaca
     6841 gtttctcctg gcctgttccc cagtctgtcc ttcccctgtg gttgagggcg ccctttacct
     6901 ttggtagacc gtgggggagc caagctggtc ccagacagga acttcctctc tgggtgcccc
     6961 cagctgctct accaccccca aatccttggg ttcaatgttt actttctcat tcggatgcca
     7021 gcaatgatgg agcctcccag ggcgtcccca gtgcggtggg gggcactggg aagggtgcgg
     7081 tgggggcagt gggaagggtg tttccaccct ctgcagtttt gactctgccg gggtgtagag
     7141 ggtgccagga ccctcagggc ccgcccggcc ccccagccct gccattacgg gttgtctgac
     7201 cgtacgcatg tgacattttt gttgttgata agcttcgccc cattacccca acccccccac
     7261 acccatgtca ccctgctgga ggccccccac ataggaggcc agagcgtatt tatttccata
     7321 gtgagcaggt tgtttctctt agaaaaagga agatagactt ggaaatgatt ttaaaagtca
     7381 gatctacatc ttggacagct tcccccaccc cccaaccccc ctcctcatcc tcttcagggt
     7441 taatttccat gaattttttt ttcttgtgtg taaaatcaaa ctgaagggaa gaaaattatt
     7501 attttggcat tcagaaccaa tccctgtaga tagactgcca tacagactct ttcttggaac
     7561 tttgtttctt gtagaaacaa gtgggaagac tttttccccc cctctcctca tttctttgta
     7621 cttcaaaaaa gaaaaaagaa aaaaaaaaaa aaagaaaacc aaccaacaac aacaaaaaga
     7681 cacacaaaaa cagcaagtct catccccctc agaaggcaga gcaggcatgt aaatacttct
     7741 ggaccgcgac tgttgtgacc cagagccctc accatgatga agtgctccgg gtggggctga
     7801 ccccacccgc ggaccaggcg gcggcagcct cttggtatct cagcttgtgt caagcttcct
     7861 tatgtaaatt ctgtacaaag aattgttttt ttcctttctc tctgtcttgg tggttttgtt
     7921 gtggtttttc tttctttcct tttttctttt ttaaattctc cacaggccct ctgtgtttga
     7981 gactgtgccc accggtccga aggtcgagag gatccttggc attaagacac aaggggcacc
     8041 tgggcacagc gccgaccttc tcttccgttt gcagttcact gcataattgt gcaaatgagg
     8101 aaaaaaaaga tttatttttc acaagaagaa atgtgtagcg tgtagagatg gctagtttga
     8161 gttacttctg cagccggtcc ctctaggggg ctatcttcat ctttcctact aacgtccacc
     8221 accaaaggaa aggtgcccga aagccaagga ggagctgcct ggtccctggc agaacctcac
     8281 tgagccctgt catgggatct gcacgcatta accttggctg acttcagggt gaggtgtgct
     8341 gccccctccc caaacctctg gctctccccc ctccccaagg gtttgcaata atcctgatat
     8401 gtgggcccat ttttctttga aagcttttgt tatcattgaa tagatctctg cttttgaagg
     8461 gtcaggggtt tctgatattt ttttttccct ctcctctccc tgtccctgca aagaagagaa
     8521 ccaataaatt ttagggttgt ctgtgcgtgt agactctgtc atccgtatgt aacttgtttc
     8581 tgaagagaag tgtttccgtt gtgggtgtgt ctcgctgtaa atacttgttc atatttttgt
     8641 gaattcaata ctatgtacca ttgtattata gtaactttta taaagcaaac cataaatata
     8701 ctgacttttc ttaca
//
