LOCUS       XM_039101225            7464 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SET domain containing 1A, histone
            lysine methyltransferase (Setd1a), transcript variant X5, mRNA.
ACCESSION   XM_039101225
VERSION     XM_039101225.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7464
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7464
                     /gene="Setd1a"
                     /note="SET domain containing 1A, histone lysine
                     methyltransferase; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 27 ESTs, 4 long
                     SRA reads, 7 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 17 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:309001"
                     /db_xref="RGD:1311624"
     CDS             1646..6817
                     /gene="Setd1a"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase SETD1A
                     isoform X1"
                     /protein_id="XP_038957153.1"
                     /db_xref="GeneID:309001"
                     /db_xref="RGD:1311624"
                     /translation="MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDG
                     VHFSVSDSKYTPVEDLQDPRCHVRSKTRDFSLPVPKFKLDEFYIGQVPLKEVTFARLN
                     DNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSV
                     MGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSSGATTETTEAR
                     RRSSSDTAAYSAGTTVGGTPGNGTPCSQDTNFSSSRQDTPSSFGQFTPQSSQGTPYTS
                     RGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDSFSRRHFSASSAPATTATATSATAAA
                     TVASSSSSSSSSSSSSSSSSSSSASQFRGSDSSYPAYYESWNRYQRHTSYPPRRATRE
                     DPSGAPFAENTAERFPPSYTSYLAPEPNRSTDQDYRPPASEAPPPEPPEPGGGSGGGG
                     GGGSGGGGGAPSPEREEARTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLL
                     KEQRSKFSFLASDTEEEEENSSAGPGARDAGGEVPSGAGHGPCTPPPAPANFEDVAPT
                     GSGEPGAARESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPP
                     PPPPPYLASLPLGYPPHQPAYLLPPHPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRL
                     GAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPPQEAAYG
                     LPYALYTQGQEGRGAYSREAYHLPLPMAAEPLPSSSVSGEEARLPHREEAEIAESKAL
                     PSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQ
                     QAKEEDKEKMKLKEPGMLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPS
                     EISEASEEKRPRPSTPAEEDEDDPEREKEAGEPGRPGTKPPKRDEERGKTQGKHRKSF
                     ALDSEGEEASQESSSEKFVLFLKDEDDDEEDEEDEEREEAVDATKKEAEASDGEDEDG
                     DSSSQCSLYADSDGEDGSTSDSESGSSSSSPSSSSSSSSSSSSESSSEEEEQSAVIPS
                     ASPPPREVPEPLPAPDEKPETDRVVDSPVMPLPEKETTSTQPAGPAEEPPPNIPQPPP
                     EPPAGPPDPPPRLDERPSSPIPLLPPPKKRRKTVSFSATEEAPVPEPSTASPLQAKSP
                     GPVSRKVPRVVERTIRNLPLDHASLVKSWPEEVARGGRNRAGGRVRSTEEEEATESGT
                     EVDLAVLADLALTPARRGLAAIPTGDDSEATETSDEAERPSPLLSHILLEHNYALAIK
                     PPPTTPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEPKQPLQQQQHPEQEGED
                     EEEDEEEESESSESSSSSSSSDEEGAIRRRSLRSHTRRRRPPLPPPPPPPPSFEPRSE
                     FEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLSTPKR
                     KRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQPEGVDTQGTNRVLSER
                     RSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMV
                     IEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPN
                     CYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN"
ORIGIN      
        1 tctgaactct tttttttttt tttccttctc ttttcttttt tttccggagc tggggaccga
       61 acccagggcc ttgcggttcg gtaggcaagc gctctaccac tgagctaaat ccccaacccc
      121 gaactcttgt tcttaaacgt gggaattcat gctttcttga acgatctctt ttatcttata
      181 ggactattca caacttctct catgtagtca tcacagacat ctcagtaaac aagttttata
      241 tttcccatct tataaaggca agaggtcaag aggctgacct ggcccacagc cacagaatta
      301 gtctatgacc tcggttacct ttaccatctt atagggattt gggggaggga gagggaactg
      361 gtacccttca attgggacaa aacaaaggaa cctcatctcc tgtaccttca tatgcatttc
      421 cccctcagcc tcagaatttt aagagtataa atcttacctt gtacagattc cttttattac
      481 ttgaaatggt caattaaaat aattggacca ggctccaata atttcctacc actatcgtga
      541 gggctgcagt aaatattgac caatagccat ctattctgga gggataacct gaaactgagg
      601 gaagtcaaag gcttgctcag tatcctataa tgaggggctc ttgaagaggg gacacttaag
      661 gtatcttcag cctagaagta gacttggcga gagcgcagtt cttccagaga ccagagagcc
      721 tctatacacc tggtgaaagg ggtgttgaac cttgggacca tctcagttcc gagtttccaa
      781 gtgaagcctg aaccaggctt aaccttaacc ttagcactgg gatcctatgg gtatacggaa
      841 gccttgccta agaactgccc aaggataatt gggttacttt cagatcttta ctctttatag
      901 ggatccactt aaaggtcttt gtgactttaa gctcaacgga accctgagac agctttaaat
      961 tttagcctct agttacgcct ccctaatagc caaaacgaac actttaaaac tggcccaagg
     1021 gaggtgtaac taaggtgctg gcctagtaca ctgaaggccc tgagttagat ttcccagcat
     1081 gctctaagcc ggttatggtg tgcacacctg taagtccagc actcaggaaa tagaggcaaa
     1141 agaatcagga gttcgaggcc atcctccgtt atatagcaag ttcgacgtct tgctgtctga
     1201 aaaacaagag cccgggtaga aaagcgggaa ggaaccgatc atttcattat gtgctccggt
     1261 aggcaaagtg cctgagtcac ccctcctggt tgtatttttc cacctcccat cccgcccagg
     1321 ttttagtgga ttctacggga agcggcccgt tacgccttgc tccgcacgcc tggccacgcc
     1381 tctctcacta gccccgccca caataggatc cgcagattcg ctattcgact ccttaggatt
     1441 atttgggaag ctttccttgt ctgaaaaatt tcatgaaacg ctgagaagac tttttccgta
     1501 caaccatttc gcactaaata ggaagtgggc ggctccttga gttgttctac taagaaaaat
     1561 ccaggaatag cggtcaactc cgccaacagg gctcggcgaa ccaggcgtga ttttcttgac
     1621 tctaccgcag tgtaaatgag cagagatgga ccaggaaggt gggggagatg ggcagaaagc
     1681 cccgagcttc cagtggcgga actacaagct catagtggat cctgctttgg accctgcttt
     1741 gcgcaggcct tctcagaagg tgtaccgcta tgatggagtc cacttcagtg tcagtgactc
     1801 aaagtatacc cctgtggaag acctccaaga cccccgctgt catgtcaggt ccaaaaccag
     1861 agacttttcc ctcccggtac ctaagtttaa gctggatgaa ttctatatcg gacaggttcc
     1921 actgaaggaa gtaacttttg cgaggctcaa tgacaatgtg cgggaaacct tcctgaagga
     1981 tatgtgccgg aagtatggtg aggtggaaga agtggagatt cttcttcatc cccgtactcg
     2041 aaagcaccta ggcctagctc gtgtgctctt caccagcact cggggtgcca aggaaactgt
     2101 caaaaacctc cacctcacct ctgtcatggg caatatcatt catgcccagc ttgatatcaa
     2161 aggccaacaa cgaatgaagt actatgaatt gattgtcaat ggctcttaca ctcctcagac
     2221 tgtgcccact gggggcaagg ccttgagtga gaagttccag ggttcttctg gtgcaaccac
     2281 tgagacgact gaagcccgcc gacggtcttc ctcggacaca gctgcctatt cagcaggcac
     2341 tactgtgggg ggcacccctg gcaatggcac tccctgctcc caagatacaa atttctccag
     2401 cagtcgacaa gataccccat cttcttttgg ccagttcacc cctcagtcct cccaaggaac
     2461 cccctacaca tctcggggta gcacccccta ctctcaggac tctgcctact ccagcagcac
     2521 cacttcaacc tccttcaaac cccggcggtc agagaacagc tatcaagatt ctttttctcg
     2581 ccgccatttc tctgcatctt cagcccctgc aaccactgct actgccacct cagcaactgc
     2641 tgcagctact gtggcctcct catcctcatc ctcctcatca tcgtcgtcct cttcctcctc
     2701 atcgtcttct tcctcagcct ctcaatttcg tggttctgac tctagctacc cagcatatta
     2761 tgaaagctgg aatcgttacc agcgccatac ttcctatcca cctcgccggg caactaggga
     2821 ggacccttct ggggctccat ttgctgaaaa tacggctgag cgcttcccac cttcctatac
     2881 ctcttatttg gcccctgagc ccaaccgatc cactgaccaa gactaccggc ctcctgcctc
     2941 agaggctcca cctccagagc ctccagaacc tggtggtggt agtggtggtg gtggtggtgg
     3001 tggtagtggt ggtggtggtg gggcacccag ccctgagaga gaagaagccc ggacttcccc
     3061 acgcccagct tcacctgcac gttctggctc cccagcccca gagaccacca acgagagtgt
     3121 gccctttgct cagcacagca gtttggattc ccgtattgaa atgctgctga aggaacaacg
     3181 ctccaaattt tctttcttgg cttctgatac agaggaagag gaagagaaca gcagtgcagg
     3241 ccctggggct agagatgccg ggggtgaggt gccttctggg gcaggtcatg ggccctgcac
     3301 accccctcct gccccagcta attttgaaga tgtagcacct acagggagtg gagaaccagg
     3361 ggctgcccgg gagtcaccaa aggccaatgg acagaaccag gcttctccat gttcttccgg
     3421 agaagatatg gagatctctg atgatgacag gggtggctca ccacctccag ccccaacacc
     3481 cccacagcag ccaccgccgc ctccgcctcc accgcctccc cctcctcctc cctaccttgc
     3541 ctcccttccc ctaggctatc ctccccacca acctgcctac ctcctcccac cccacccaga
     3601 tggcccacca ccccctgagt accctccacc acccccacca ccaccccaca tctatgactt
     3661 tgtgaactcc ctggaactta tggatcgact tggggcacag tggggaggga tgcccatgtc
     3721 cttccagatg cagacccaga tgttaacacg gctccaccaa ttacggcagg gcaagggatt
     3781 gactgcagcc tcagctggtc ctcctggcgg ggccttcggc gaggccttcc tcccttttcc
     3841 acctccacaa gaggcagcct atggcttgcc ctatgctctg tacacacaag ggcaagaagg
     3901 tcgtggggcg tactcccggg aggcctacca cttgcccttg cctatggcag ccgagcccct
     3961 gccctcttcc tcagtctcgg gagaggaggc ccggctgcct catcgggagg aagcagagat
     4021 agcagaaagc aaggccctac cgtcagcagg cacagtgggt cgtgtgctgg ccacccttgt
     4081 ccaagagatg aagagcatta tgcagcgaga ccttaaccga aagatggtcg agaatgtggc
     4141 ctttggagcc tttgaccagt ggtgggagag caaggaagag aaggccaagc cattccagaa
     4201 tgcagccaaa cagcaagcca aggaagagga caaagaaaag atgaagctca aagagcccgg
     4261 catgctgtcc ctcgtagact gggccaagag tggcggtatc acaggcattg aggcctttgc
     4321 ctttgggtca gggctgcgag gggccctgcg gttgccttca ttcaaggtaa aacggaaaga
     4381 gccatcagaa atttcagagg ccagtgagga aaagaggccc aggccctcta ctccagctga
     4441 ggaagatgaa gatgatcctg agcgagagaa ggaagctgga gaaccaggac gtccagggac
     4501 caagcctccg aagcgagatg aagaacgagg caagacccaa ggcaaacacc ggaaatcctt
     4561 tgctctggac agtgaagggg aggaggcatc ccaggagtct tcctcagaga agtttgtctt
     4621 gtttcttaag gatgaggatg atgatgagga agatgaggaa gatgaagagc gggaagaagc
     4681 tgtggatgcc accaagaagg aagcagaggc atcagatggt gaggatgagg acggcgactc
     4741 gtcctcccag tgctctctgt atgctgattc agacggtgaa gatggtagca cgtcggactc
     4801 cgagagcggt agctcctctt cctctccatc atcgtcatcc tcatcttcct catcttcctc
     4861 atcagagtcc tcctctgaag aagaagaaca gtcagcagtc attccctcag cttcaccacc
     4921 tcccagagaa gttccagagc cccttccagc tcctgatgaa aagcctgaga cagacagggt
     4981 tgtagactcc cctgtcatgc ctctccctga aaaggaaaca acatccacac agcctgcagg
     5041 tcctgctgaa gaaccacctc ctaacatacc acagcctccc ccggagccac cagctggacc
     5101 tccagaccct cccccacgcc tggatgagcg cccctcttct cctattcctc tcctaccccc
     5161 acccaagaaa cgccggaaaa ctgtttcctt ctctgctaca gaggaggcac cagtcccaga
     5221 accttccaca gcctctccac tgcaggccaa gtctcctggt ccagtctctc gaaaagttcc
     5281 ccgggttgta gagcggacca ttcgtaacct acccctggac catgcatctc tggtcaagag
     5341 ttggcctgag gaggtggccc gagggggtag gaatcgagct ggaggtcgtg tccgctctac
     5401 tgaggaagaa gaggccactg agtcagggac agaagtagac ttggcagtac tggctgacct
     5461 agccctgacc ccagctcgtc gtgggttggc tgccataccc actggtgacg actcagaggc
     5521 cacagagacc tcagatgagg ctgagcgccc aagccctcta ctcagccaca ttctcttaga
     5581 acacaactat gccctagcca tcaagccccc gcctaccaca ccagcacctc ggcccctgga
     5641 gccagctcct gcccttgctg cactcttcag ttctccagct gatgaggtct tggaggcccc
     5701 tgaggtggtg gtggctgagg cagaagagcc aaagcaacct ctgcagcagc agcagcatcc
     5761 agagcaggaa ggagaggatg aggaagaaga tgaagaagag gagtccgagt cttcagagag
     5821 cagcagcagc agcagtagca gtgatgagga aggggcaatc aggaggcgca gcctccgctc
     5881 ccacactcga agaaggcggc caccactccc acccccaccc ccaccgcctc cttcctttga
     5941 gccaaggagt gaatttgagc aaatgaccat cttatatgat atttggaact caggcctgga
     6001 cttagaagac atgagctatt tgcgactcac atatgagcgg ctgctgcagc aaaccagtgg
     6061 cgctgactgg cttaatgaca cccactgggt ccatcacaca atcaccaacc taagcactcc
     6121 aaagcgcaaa cgtcggcccc aagatgggcc ccgggagcat cagacaggct ctgcacgcag
     6181 tgaaggttac taccccatca gcaagaagga gaaagacaaa tacttggatg tgtgccctgt
     6241 ctcagcccgg cagccggaag gtgtagacac tcaggggact aatcgggtac tttctgagcg
     6301 gcggtcagag cagcggcggt tactaagcgc tattggcact tcagccatca tggatagtga
     6361 tctgctaaag ctaaatcagc tcaagttccg gaagaagaaa ctccgatttg gccggagccg
     6421 tatccatgag tggggtctgt ttgccatgga acccattgca gctgacgaga tggtgataga
     6481 atatgttggc cagaacatcc gccagatggt agcagacatg cgggagaagc gctatgttca
     6541 ggagggcatt ggcagcagct accttttccg ggtggatcac gacaccatca ttgatgccac
     6601 caagtgtggc aatcttgcca ggttcatcaa ccactgctgc acgcccaact gctatgctaa
     6661 ggtgatcacc attgagtctc agaagaagat cgtgatctac tcaaagcagc ccattggcgt
     6721 ggatgaggag atcacctatg actacaagtt cccactagaa gacaacaaga ttccatgtct
     6781 gtgtggcact gaaagctgcc gtggctccct caactgaggt ggggcaggac cggtgccctc
     6841 acccctattt attccccctt ggtgccctaa gctcccagca cccccagcct tattgggctc
     6901 agcagggccc actgccccca cctccacatg tgggataggg agccctgagt ccagcaaggg
     6961 agcctcagtc ctttgaggtt aacttctgcc ttccctatac cccatgccca accgccctct
     7021 taattttttt ttctttgcga agaagaagct gtaaatgttt tgtagctgcc agcagctgtt
     7081 tcctgtggaa acctggggta ccagcctgta tagatgctat tcttgggggc tgcatagccc
     7141 tttgcttcat gttaatgggg acttcccctt ctgccctatg tgcacccctc cccagtttag
     7201 gggtctctgg ggcagtggcc atgttctccc cctggggggg cctttggccc ctagtcctgg
     7261 gaactctgtg cctggaaccc tgcctcatct gttcctgcca gaccctgtgg gtcaccctcc
     7321 caccctggtg tctcagggct ctggctcagt aggccaggat ggtggggggc aggcccttct
     7381 tgttgggctg gactgtacat agtgttaata gtgaaaccca acaccacatt tttataattg
     7441 tgattaaact ttattgtaca aaaa
//
