LOCUS       NM_001135867            1737 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus serpin family B member 12 (Serpinb12), mRNA.
ACCESSION   NM_001135867 XM_222499
VERSION     NM_001135867.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1737)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 1737)
  AUTHORS   Askew,Y.S., Pak,S.C., Luke,C.J., Askew,D.J., Cataltepe,S.,
            Mills,D.R., Kato,H., Lehoczky,J., Dewar,K., Birren,B. and
            Silverman,G.A.
  TITLE     SERPINB12 is a novel member of the human ov-serpin family that is
            widely expressed and inhibits trypsin-like serine proteinases
  JOURNAL   J Biol Chem 276 (52), 49320-49330 (2001)
   PUBMED   11604408
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Mar 27, 2023 this sequence version replaced NM_001135867.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.46053.1,
                                           SRR26643294.47163.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000013.1  23567023-23567138
            117-172             JAXUCZ010000013.1  23571383-23571438
            173-358             JAXUCZ010000013.1  23585067-23585252
            359-484             JAXUCZ010000013.1  23587608-23587733
            485-622             JAXUCZ010000013.1  23588039-23588176
            623-740             JAXUCZ010000013.1  23588627-23588744
            741-883             JAXUCZ010000013.1  23595001-23595143
            884-1051            JAXUCZ010000013.1  23596662-23596829
            1052-1737           JAXUCZ010000013.1  23597644-23598329
FEATURES             Location/Qualifiers
     source          1..1737
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13p11"
     gene            1..1737
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /note="serpin family B member 12"
                     /db_xref="GeneID:304692"
                     /db_xref="RGD:1566382"
     exon            1..116
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            117..172
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            173..358
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..1456
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /note="serine (or cysteine) peptidase inhibitor, clade B,
                     member 12; serine (or cysteine) peptidase inhibitor, clade
                     B (ovalbumin), member 12; serpin peptidase inhibitor,
                     clade B (ovalbumin), member 12; serpin B12-like"
                     /codon_start=1
                     /product="serpin B12"
                     /protein_id="NP_001129339.1"
                     /db_xref="GeneID:304692"
                     /db_xref="RGD:1566382"
                     /translation="MDSLVAANNKFCFDFFQEISKDDAHKNIFVCPLSLSAAFGMVRL
                     GARGDSAQQIDEVLHFNELPKDERKEPSEPSSKSKASDSSLEGQKQTTASQGQQGEST
                     NEHRLLGCHFGKLLSRIDRDKAHYTLSMANRLYGEQEFPICPEYSDDITEFYHTTIES
                     VDFQKDTEKSREEINFWVESQSQGKIKELFDKEAIDNSTVLVLVNAVYFKAKWEKEFD
                     SENTVDAPFCLSENEKKTVKMMNQKGQFRIGFIEELQAQILEMKYTTGKLSMLVLLPS
                     SSEDNVKSLQELEKKINHEKLLAWSNPENMSEKPVAISFPQFIMEDSYDLNSVLQDMG
                     IRDVFDGTKADLTGISKSPSLHLSKVVHKTFVEVDEMGTQAAAASGAVVAEKALPSRV
                     EFNANRPFLFFIRHNGTQSLLFCGRVYSP"
     exon            359..484
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            485..622
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            623..740
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            741..883
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1051
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1737
                     /gene="Serpinb12"
                     /gene_synonym="RGD1566382"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acctctcctt accagtctct gcaggctgaa caacttggct gttcctacct tgaggtattg
       61 aactgacttc atcacagctt ggactttagc tggagacagc cgtcactagg ttgcagggtg
      121 tggattgaaa cttccctggc caggactcag aagcaaatct gaaggcaaga agacagtaac
      181 aagtttgaca atggactctc ttgttgcagc aaataacaaa ttttgcttcg attttttcca
      241 agagattagc aaagatgatg ctcataaaaa tatctttgta tgccctctga gtctctcagc
      301 tgcctttggt atggtccgcc tgggagctag aggggacagt gcacaacaga ttgatgaggt
      361 attacatttc aatgagcttc ccaaggatga acgcaaagag cccagtgaac cctcttcaaa
      421 aagcaaagca tctgacagct ctctggaagg gcaaaaacaa accacagctt ctcagggtca
      481 gcagggtgaa tctacaaatg agcatcgatt gcttggctgc cactttggga aacttctctc
      541 cagaatagac agagacaaag ctcattatac tctgagtatg gccaacagac tctatggaga
      601 gcaggaattc ccaatctgcc cggaatactc tgatgacata actgaatttt accacacaac
      661 aatcgaaagt gtagatttcc agaaggatac ggagaaatca agagaagaga ttaacttctg
      721 ggttgaaagt caaagccaag gaaaaatcaa agaactgttt gacaaggagg ctattgataa
      781 ttcgactgtg ctggtgctgg tgaatgctgt ttacttcaag gccaagtggg agaaagaatt
      841 cgactctgaa aacactgttg atgcaccttt ctgtctcagt gagaatgaaa agaagactgt
      901 taagatgatg aatcagaagg gtcagtttag aattggcttc attgaggagc tgcaggcaca
      961 gatcctggaa atgaagtata ccacgggcaa actcagcatg ctggtcctgc ttccatcttc
     1021 ctcagaagac aatgtgaaga gcctgcaaga gcttgaaaag aaaataaacc acgaaaaact
     1081 acttgcctgg agtaacccag aaaacatgtc agaaaaaccc gtagccattt ccttccccca
     1141 gttcatcatg gaagatagct acgacctcaa ctcggttcta caggatatgg gcattaggga
     1201 tgtctttgat ggaacaaagg ctgaccttac tggaatctct aagagtccca gtctgcattt
     1261 gtccaaagtt gtccacaaga cctttgtgga agtggatgag atgggcaccc aggcagctgc
     1321 agccagtggg gctgtggttg cagagaaggc ccttccgtcc agggtggaat ttaatgccaa
     1381 ccgcccattc ctctttttca tccgacacaa tggaacccag agtctacttt tctgtggcag
     1441 agtctactcc ccttgaatct actctggctt ttgatgtgtt gaggggaatg gtaatatgtt
     1501 ttccccttgt aaaacaaggg catgtgggtt ttggctgagt gcctgaaaca gaccacctgc
     1561 tgctgcagtt gtgcacggaa tcccacaagc cgcccctgag ttttgttccc accctctgtc
     1621 accagaagcc agatctctcc acctgttaat gaagtagcct tgctttctcc ctaatcttta
     1681 ctgctctaca ctttcaagca tataaattca ccttctatga tttggaggtc aacacaa
//
