LOCUS       NM_133617               1622 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus serpin family A member 10 (Serpina10), mRNA.
ACCESSION   NM_133617
VERSION     NM_133617.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Almawi,W.Y., Al-Shaikh,F.S., Melemedjian,O.K. and Almawi,A.W.
  TITLE     Protein Z, an anticoagulant protein with expanding role in
            reproductive biology
  JOURNAL   Reproduction 146 (2), R73-R80 (2013)
   PUBMED   23690629
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  AUTHORS   Van de Water,N., Tan,T., Ashton,F., O'Grady,A., Day,T., Browett,P.,
            Ockelford,P. and Harper,P.
  TITLE     Mutations within the protein Z-dependent protease inhibitor gene
            are associated with venous thromboembolic disease: a new form of
            thrombophilia
  JOURNAL   Br J Haematol 127 (2), 190-194 (2004)
   PUBMED   15461625
REFERENCE   3  (bases 1 to 1622)
  AUTHORS   Bray,C., Son,J.H., Kumar,P., Harris,J.D. and Meizel,S.
  TITLE     A role for the human sperm glycine receptor/Cl(-) channel in the
            acrosome reaction initiated by recombinant ZP3
  JOURNAL   Biol Reprod 66 (1), 91-97 (2002)
   PUBMED   11751269
REFERENCE   4  (bases 1 to 1622)
  AUTHORS   Yin,Z.F., Huang,Z.F., Cui,J., Fiehler,R., Lasky,N., Ginsburg,D. and
            Broze,G.J. Jr.
  TITLE     Prothrombotic phenotype of protein Z deficiency
  JOURNAL   Proc Natl Acad Sci U S A 97 (12), 6734-6738 (2000)
   PUBMED   10829076
REFERENCE   5  (bases 1 to 1622)
  AUTHORS   New,L., Liu,K., Kamali,V., Plowman,G., Naughton,B.A. and
            Purchio,A.F.
  TITLE     cDNA cloning of rasp-1, a novel gene encoding a plasma protein
            associated with liver regeneration
  JOURNAL   Biochem Biophys Res Commun 223 (2), 404-412 (1996)
   PUBMED   8670294
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088113.1.
            
            On Jan 2, 2005 this sequence version replaced NM_133617.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088113.1, FQ219699.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1622
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /note="serpin family A member 10"
                     /db_xref="GeneID:171154"
                     /db_xref="RGD:621220"
     exon            1..88
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /inference="alignment:Splign:2.1.0"
     exon            89..821
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1438
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /note="protein Z-dependent protease inhibitor; PZI;
                     RASP-1; serpin A10; PZ-dependent protease inhibitor;
                     regeneration-associated serpin 1; serpin peptidase
                     inhibitor, clade A (alpha-1 antiproteinase, antitrypsin),
                     member 10; protein Z-dependent protease inhibitor-like;
                     serine (or cysteine) proteinase inhibitor, clade A
                     (alpha-1 antiproteinase, antitrypsin), member 10; plasma
                     protein associated with liver regeneration; serine (or
                     cysteine) peptidase inhibitor, clade A (alpha-1
                     antiproteinase, antitrypsin), member 10; serpin peptidase
                     inhibitor, clade A, member 10"
                     /codon_start=1
                     /product="protein Z-dependent protease inhibitor
                     precursor"
                     /protein_id="NP_598301.2"
                     /db_xref="GeneID:171154"
                     /db_xref="RGD:621220"
                     /translation="MRVVSSLFLPVLLAEVWLVSSFNLSSHSPEAPIRLVSQDYENQT
                     WEEYEWADPRDDNEYWLRASQQLSNETSSFGFSLLRKISMRHDGNVIFSPFGLSVAMV
                     NLMLGAKGETKVQVENGLNLQALSQAGPLILPALFKRVKETFSSNKKLGLTQGSFAFI
                     HKDFEIKKTYFNLSTMYFDTEYVPTNFRNSSQARGLMNHYINKETEGKIPKLFDEINP
                     ETKLILVDYILFKGKWLTPFDPIFTEADTFHLDKYKAVKVPMMYREGNFASTFDKKFR
                     CHILKLPYQGNATMLVVLMEKSGDHLALEDYLTTDLVEMWLQDMKTRKMEVFFPKFKL
                     NQRYEMHELLKQVGIRRIFSTSADLSELSAVARNLQVSKVVQQSVLEVDERGTEVVSG
                     TVSEITAYCMPPVIKVDRPFHFIIYEEMSQMLLFLGRVVNPTVL"
     exon            822..1095
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1246
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1598
                     /gene="Serpina10"
                     /gene_synonym="Rasp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaatattta ctgaaggctt cagactgcaa aacgtatgct tacttctttg ctctgaatga
       61 tcttctctac accagaggtc cggaactgga tgaagggaag tggcccctgg cctccacagc
      121 tgaccacatg agggtggttt ctagcctctt tcttcctgtg ctccttgcag aggtgtggct
      181 ggtgagcagt ttcaatctca gctcccattc accagaggct cccattcgcc tggtgtctca
      241 ggattacgag aatcaaactt gggaagagta cgaatgggct gatcccaggg atgataatga
      301 atactggcta agggccagcc agcaactctc caatgagact tcaagctttg ggttcagcct
      361 gcttcgaaag atctccatga ggcacgatgg caatgtgatc ttctcaccat ttggcctgtc
      421 tgtggctatg gtgaacttga tgctgggggc caagggagag accaaagtgc aggtagaaaa
      481 tgggctcaac ctacaggccc tgagccaggc aggacccctg atccttccag ccctcttcaa
      541 gagagtcaaa gagacctttt ccagcaacaa gaaattgggc ctcacccagg gtagctttgc
      601 cttcatccac aaggactttg aaattaaaaa gacctatttc aatctatcca caatgtattt
      661 tgatacagag tacgtgccta caaattttcg aaattcttca caagccagag ggctcatgaa
      721 ccattacatt aacaaagaga ctgaggggaa aatccccaag ctttttgatg agattaatcc
      781 tgaaacaaag ttaattctgg tggactacat cttgttcaaa ggcaagtggc tgactccatt
      841 tgaccccatc ttcactgagg ctgacacttt ccacctggac aaatacaagg cagttaaggt
      901 gcccatgatg taccgggaag ggaactttgc ctctaccttt gataagaagt tccgttgtca
      961 catcctcaaa ctgccctacc aaggaaatgc caccatgcta gtggtcctta tggagaaatc
     1021 gggtgaccac ttggccctgg aggactactt gaccacagac ctcgtggaga tgtggctcca
     1081 ggatatgaaa accagaaaaa tggaggtctt ctttcccaag ttcaagctga accagaggta
     1141 tgagatgcat gagctgctca agcaggtggg aattaggagg atcttctcca cctcagctga
     1201 cctcagcgaa ctctcagccg tggcacgaaa tcttcaggtg tccaaggtcg tacaacagtc
     1261 agtgcttgag gtggatgaaa ggggaactga ggtggtgtca gggacggtgt cagagatcac
     1321 cgcttactgc atgcctcctg tcatcaaagt ggaccggcct tttcacttca tcatctacga
     1381 ggagatgtcc cagatgctcc tatttcttgg cagggtggtg aacccgacag ttctgtgact
     1441 cgggcatgta ggacctcggc caccacaggt gctgagccag aggtgtctga atcacaagac
     1501 gctgttggta gacggtaaag gatgcattct ctgtacccag ccagtttgct atggctgttg
     1561 tctgattaac actgaaatta aaatgactca tactttaaaa aaaaaaaaaa aaaaaaaaaa
     1621 aa
//
