LOCUS       NM_001399502             557 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus small EDRK-rich factor 1 (Serf1), mRNA.
ACCESSION   NM_001399502 XM_577983
VERSION     NM_001399502.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Merle,D.A., Witternigg,A., Tam-Amersdorfer,C., Hartlmuller,C.,
            Spreitzer,E., Schrank,E., Wagner-Lichtenegger,S., Werzer,O.,
            Zangger,K., Kungl,A.J., Madl,T., Meyer,N.H. and Falsone,S.F.
  TITLE     Increased Aggregation Tendency of Alpha-Synuclein in a Fully
            Disordered Protein Complex
  JOURNAL   J Mol Biol 431 (14), 2581-2598 (2019)
   PUBMED   31034892
REFERENCE   2  (bases 1 to 557)
  AUTHORS   Falsone,S.F., Meyer,N.H., Schrank,E., Leitinger,G., Pham,C.L.,
            Fodero-Tavoletti,M.T., Holmberg,M., Dulle,M., Scicluna,B.,
            Gesslbauer,B., Ruckert,H.M., Wagner,G.E., Merle,D.A., Nollen,E.A.,
            Kungl,A.J., Hill,A.F., Cappai,R. and Zangger,K.
  TITLE     SERF protein is a direct modifier of amyloid fiber assembly
  JOURNAL   Cell Rep 2 (2), 358-371 (2012)
   PUBMED   22854022
REFERENCE   3  (bases 1 to 557)
  AUTHORS   van Ham,T.J., Holmberg,M.A., van der Goot,A.T., Teuling,E.,
            Garcia-Arencibia,M., Kim,H.E., Du,D., Thijssen,K.L., Wiersma,M.,
            Burggraaff,R., van Bergeijk,P., van Rheenen,J., Jerre van Veluw,G.,
            Hofstra,R.M., Rubinsztein,D.C. and Nollen,E.A.
  TITLE     Identification of MOAG-4/SERF as a regulator of age-related
            proteotoxicity
  JOURNAL   Cell 142 (4), 601-612 (2010)
   PUBMED   20723760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jan 10, 2022 this sequence version replaced XM_577983.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF522362.1, SRR26360194.232052.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-176               JAXUCZ010000002.1  33210001-33210176
            177-285             JAXUCZ010000002.1  33211013-33211121
            286-557             JAXUCZ010000002.1  33215858-33216129
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..557
                     /gene="Serf1"
                     /gene_synonym="RGD1565105"
                     /note="small EDRK-rich factor 1"
                     /db_xref="GeneID:502503"
                     /db_xref="RGD:1565105"
     exon            1..176
                     /gene="Serf1"
                     /gene_synonym="RGD1565105"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..358
                     /gene="Serf1"
                     /gene_synonym="RGD1565105"
                     /codon_start=1
                     /product="small EDRK-rich factor 1"
                     /protein_id="NP_001386431.1"
                     /db_xref="GeneID:502503"
                     /db_xref="RGD:1565105"
                     /translation="MARGNQREIARQKNMKKTQEISKGKRKEDSLTASQRKQRDSEIM
                     QQKQKVANEKKSMQTRDK"
     exon            177..285
                     /gene="Serf1"
                     /gene_synonym="RGD1565105"
                     /inference="alignment:Splign:2.1.0"
     exon            286..557
                     /gene="Serf1"
                     /gene_synonym="RGD1565105"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttgtgggtc ggtgggcggg gcggccggct gacagagcga ggcgtcgcca caccgagggc
       61 cctctcaggg ctcagccttc ctcagcgccg agcggcgacg gctgccgagc gtgcaagccg
      121 ccgttgcttc tccaggtcgc tgtcttccag tctccggcta gtggtcagca tggcccgtgg
      181 aaatcaaaga gaaattgccc gacagaaaaa tatgaaaaag acccaggaaa ttagcaaagg
      241 aaaaagaaaa gaggatagct taactgcatc tcagagaaag cagagggatt cagagatcat
      301 gcaacaaaag cagaaggtag ccaatgagaa gaaatctatg cagacaagag acaaatgatg
      361 actggctttt tggaaaacct gggtgctatt gccagtgggt gcatcatatg ctctaagatc
      421 aaaacttcac agagtgacta atcattacat gtgttataac ttgtccttat aaaaatttca
      481 aattttactt ttcagccttg cttgatgtga tgttttaaga ccattcatca aagaataaaa
      541 cctgaccatg cacgtaa
//
