LOCUS       NM_145086               1357 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Serpine1 mRNA binding protein 1 (Serbp1), mRNA.
ACCESSION   NM_145086 XM_342705
VERSION     NM_145086.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Saito,A., Souza,E.E., Costa,F.C., Meirelles,G.V., Goncalves,K.A.,
            Santos,M.T., Bressan,G.C., McComb,M.E., Costello,C.E., Whelan,S.A.
            and Kobarg,J.
  TITLE     Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and
            Affects PML Nuclear Body Formation
  JOURNAL   J Proteome Res 16 (9), 3147-3157 (2017)
   PUBMED   28695742
REFERENCE   2  (bases 1 to 1357)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1357)
  AUTHORS   Peluso,J.J., Yuan,A., Liu,X. and Lodde,V.
  TITLE     Plasminogen activator inhibitor 1 RNA-binding protein interacts
            with progesterone receptor membrane component 1 to regulate
            progesterone's ability to maintain the viability of spontaneously
            immortalized granulosa cells and rat granulosa cells
  JOURNAL   Biol Reprod 88 (1), 20 (2013)
   PUBMED   23242527
  REMARK    GeneRIF: These studies support the concept that the interaction
            between PAIRBP1-PGRMC1 is an essential component of the mechanism
            through which progesterone inhibits apoptosis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1357)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 1357)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1357)
  AUTHORS   Peluso,J.J., Pappalardo,A., Losel,R. and Wehling,M.
  TITLE     Expression and function of PAIRBP1 within gonadotropin-primed
            immature rat ovaries: PAIRBP1 regulation of granulosa and luteal
            cell viability
  JOURNAL   Biol Reprod 73 (2), 261-270 (2005)
   PUBMED   15814896
  REMARK    GeneRIF: PAIRBP1 plays an important role in mediating the
            antiapoptotic action of progesterone in ovarian granulosa and
            luteal cells.
REFERENCE   7  (bases 1 to 1357)
  AUTHORS   Peluso,J.J., Pappalardo,A., Fernandez,G. and Wu,C.A.
  TITLE     Involvement of an unnamed protein, RDA288, in the mechanism through
            which progesterone mediates its antiapoptotic action in
            spontaneously immortalized granulosa cells
  JOURNAL   Endocrinology 145 (6), 3014-3022 (2004)
   PUBMED   14988380
  REMARK    GeneRIF: RDA288 in cytoplasm and plasma membrane components of
            granulosa cells of antral follicles. Present on extracellular
            surface of plasma membrane. RDA288 plays significant role in
            mediating progesterone's antiapoptotic action in granulosa cells.
REFERENCE   8  (bases 1 to 1357)
  AUTHORS   Blasi,F., Ciarrocchi,A., Luddi,A., Strazza,M., Riccio,M., Santi,S.,
            Arcone,R., Pietropaolo,C., D'Angelo,R., Costantino-Ceccarini,E. and
            Melli,M.
  TITLE     Stage-specific gene expression in early differentiating
            oligodendrocytes
  JOURNAL   Glia 39 (2), 114-123 (2002)
   PUBMED   12112363
REFERENCE   9  (bases 1 to 1357)
  AUTHORS   Heaton,J.H., Dlakic,W.M., Dlakic,M. and Gelehrter,T.D.
  TITLE     Identification and cDNA cloning of a novel RNA-binding protein that
            interacts with the cyclic nucleotide-responsive sequence in the
            Type-1 plasminogen activator inhibitor mRNA
  JOURNAL   J Biol Chem 276 (5), 3341-3347 (2001)
   PUBMED   11001948
REFERENCE   10 (bases 1 to 1357)
  AUTHORS   Sykes,D.E. and Weiser,M.M.
  TITLE     The identification of genes specifically expressed in epithelial
            cells of the rat intestinal crypts
  JOURNAL   Differentiation 50 (1), 41-46 (1992)
   PUBMED   1639225
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079337.1.
            
            On Jan 21, 2005 this sequence version replaced XM_342705.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079337.1, FQ228026.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q31"
     gene            1..1357
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /note="Serpine1 mRNA binding protein 1"
                     /db_xref="GeneID:246303"
                     /db_xref="RGD:619907"
     exon            1..378
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1244
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /note="plasminogen activator inhibitor 1 RNA-binding
                     protein; RNA binding protein RDA288; PAI1 RNA-binding
                     protein 1; PAI-1 mRNA-binding protein; hypothetical RNA
                     binding protein RDA288"
                     /codon_start=1
                     /product="SERPINE1 mRNA-binding protein 1"
                     /protein_id="NP_659554.1"
                     /db_xref="GeneID:246303"
                     /db_xref="RGD:619907"
                     /translation="MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGG
                     GVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVADKKEETQPPVALK
                     KEGIRRVGRRPDQQLQGDGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIER
                     PIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGG
                     SGSHNWGTVKDELTDLEQSNVTEETPEGEEHPVADTENKENEVEEVKEEGPKEMTLDE
                     WKAIQNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPAND
                     ITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
                     "
     exon            379..529
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            530..670
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            671..760
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            761..835
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            836..1013
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1187
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1348
                     /gene="Serbp1"
                     /gene_synonym="Pai-Rbp1; Pairbp1; Rda288"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggcgcttt tggctcggcg cggtccgctg caatccgtgg aggaacgcgc cgccgagcca
       61 ccatcatgcc tgggcaccta caggaaggct tcggctgcgt ggtcaccaac cgattcgacc
      121 agctatttga cgacgaatcg gaccctttcg aggtactgaa ggcagcagag aacaagaaaa
      181 aagaagccgg cgggggcggc gttgggggcc ccggggccaa gagcgcggct caggccgcgg
      241 cccagaccaa ctccaacgcg gcaggcaaac agttgcggaa agagtcccag aaagaccgca
      301 agaacccgct gccccccagc gtcggcgtgg ctgacaaaaa ggaggagacg cagccgccgg
      361 tggcgcttaa gaaagaagga ataaggcgag ttggaagaag acctgatcaa caacttcagg
      421 gtgatgggaa aataattgat aggagaccag aaaggcgacc acctcgtgaa agaagatttg
      481 aaaagccact tgaagaaaaa ggtgaaggag gtgaattttc agttgataga ccgatcatcg
      541 aacggcctat ccgaggccga ggtggtcttg gaaggggtcg aggtggccgt ggccgtggaa
      601 tgggccgagg tgatggattt gattctcgtg gcaagcgtga atttgatagg catagtggaa
      661 gtgatagatc ttctttttca cattacagtg gcctgaagca tgaggacaaa cgtggaggta
      721 gcggatctca caactgggga actgtcaaag atgaattaac tgatttggag caatcaaatg
      781 tgactgagga aacacccgaa ggtgaagagc acccagtggc agacactgaa aataaggaga
      841 acgaagttga agaggttaag gaagagggtc caaaagagat gactttggat gagtggaaag
      901 ctattcaaaa taaagaccga gcaaaagtag aatttaatat ccgaaaacca aatgaaggtg
      961 ctgatggaca atggaaaaag ggatttgttc tgcataaatc aaaaagtgaa gaggctcatg
     1021 cggaagattc agttatggac catcatttcc ggaagccagc aaatgatata acgtctcaac
     1081 tggagatcaa ttttggagac ctaggccgcc caggacgtgg tggcagagga ggacgtggtg
     1141 gacgtgggcg tggtggtcgt cctaatcgtg gcagcaggac tgataagtca agtgcttctg
     1201 ctcctgatgt agatgaccca gaggcattcc ccgctctggc ctaactggat gccataatac
     1261 aacactggtt cctttgtgga ccctcctgtt caaagctttt gcatgcttaa ggatcccaaa
     1321 caactaagaa ttaaaaaaaa aaaaaaaaaa aaaaaaa
//
