LOCUS       NM_001012355            1007 bp    mRNA    linear   ROD 08-MAR-2024
DEFINITION  Rattus norvegicus SUMO peptidase family member, NEDD8 specific
            (Senp8), mRNA.
ACCESSION   NM_001012355 XM_236309
VERSION     NM_001012355.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Song,J.M., Kang,M., Lee,S., Kim,J., Park,S., Park,D.H., Lee,S. and
            Suh,Y.H.
  TITLE     Deneddylating enzyme SENP8 regulates neuronal development
  JOURNAL   J Neurochem 165 (3), 348-361 (2023)
   PUBMED   36847487
  REMARK    GeneRIF: Deneddylating enzyme SENP8 regulates neuronal development.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089939.1.
            
            On Feb 18, 2005 this sequence version replaced XM_236309.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089939.1, FQ227853.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN14984043 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1007
                     /gene="Senp8"
                     /note="SUMO peptidase family member, NEDD8 specific"
                     /db_xref="GeneID:315723"
                     /db_xref="RGD:1309955"
     exon            1..48
                     /gene="Senp8"
                     /inference="alignment:Splign:2.1.0"
     exon            49..68
                     /gene="Senp8"
                     /inference="alignment:Splign:2.1.0"
     exon            69..1003
                     /gene="Senp8"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..758
                     /gene="Senp8"
                     /EC_number="3.4.22.68"
                     /note="deneddylase-1; NEDD8-specific protease 1;
                     sentrin/SUMO-specific protease SENP8; SUMO/sentrin
                     specific protease family member 8; SUMO/sentrin specific
                     peptidase 8; Sumo1/sentrin/SMT3 specific peptidase 8;
                     SUMO/sentrin specific peptidase family member 8;
                     SUMO/sentrin peptidase family member, NEDD8 specific"
                     /codon_start=1
                     /product="sentrin-specific protease 8"
                     /protein_id="NP_001012355.1"
                     /db_xref="GeneID:315723"
                     /db_xref="RGD:1309955"
                     /translation="MDPVVLSYMDSLLRQSDVSLLDPPNWLNDHIIGFAFEYFASSQF
                     HDCSDHVCFISPEVTQFIKCTSSPAEIAMFLEPLDLPHKRVVFLAINDNSNQAAGGTH
                     WSLLVYLQDKNSFFHYDSHSRSNSIHAKQVAEKLKAFLGSKGDKLVFVEEKAPAQQNS
                     YDCGMYVICNTEALCQNLFRRQPESPLQLLTPTYITKKRGEWKDLIARLAKKNRSSY"
ORIGIN      
        1 taccgagatc cctgaaggct ggttgggctg gtgaggcctg aggaatagaa gtactgctga
       61 gtggccagct tctggaattt ctgagaagcc ctgctcaata caagatggac cctgtggtct
      121 tgagttatat ggacagtcta ttgcgacaat cagatgtctc actattggac cctccaaact
      181 ggctcaacga ccacattatt gggtttgcct ttgaatactt tgccagtagt cagtttcatg
      241 attgctcaga ccatgtctgc ttcatcagcc ctgaagtcac ccagttcatt aagtgcacca
      301 gcagccctgc agagattgcc atgttccttg aacccctgga tcttccccac aaaagagtgg
      361 tatttttagc catcaatgat aattctaacc aggcagccgg aggtacccac tggagtttgt
      421 tggtttatct ccaagataaa aatagcttct ttcattatga ttcccatagc aggagcaact
      481 caatccatgc aaaacaggta gcagagaaac tgaaggcttt cttagggagc aaaggagaca
      541 aactggtctt tgtggaagag aaagccccag ctcaacagaa cagctatgac tgtgggatgt
      601 acgtgatatg taacaccgag gccttgtgtc aaaatctctt tagacgacag ccagaatccc
      661 cactgcagct cctcaccccg acatacatca caaagaagag gggagaatgg aaagatctaa
      721 ttgccagact tgctaaaaaa aaccgaagta gctactgaag aatgcttgtg atgtttgaag
      781 tctggtcttt ctgcctttct ctatggtgac agcctcagtg cctgagggaa aaacactagt
      841 agatgaaagt ttactattcc tgcttcttta ttgttctgaa agaatgtcat cctctgcgtt
      901 ctctgaatgg gaagtttcac tgtaaccctg aggagagcag tgcattctgt gaaaatgtct
      961 ggaacttatg taccaaaacc ttaaaaaaaa aaaaaaaaaa aaaaaaa
//
