LOCUS       NM_017308               3272 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus semaphorin 6C (Sema6c), mRNA.
ACCESSION   NM_017308
VERSION     NM_017308.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Yoshida,Y., Han,B., Mendelsohn,M. and Jessell,T.M.
  TITLE     PlexinA1 signaling directs the segregation of proprioceptive
            sensory axons in the developing spinal cord
  JOURNAL   Neuron 52 (5), 775-788 (2006)
   PUBMED   17145500
REFERENCE   2  (bases 1 to 3272)
  AUTHORS   Qu,X., Wei,H., Zhai,Y., Que,H., Chen,Q., Tang,F., Wu,Y., Xing,G.,
            Zhu,Y., Liu,S., Fan,M. and He,F.
  TITLE     Identification, characterization, and functional study of the two
            novel human members of the semaphorin gene family
  JOURNAL   J Biol Chem 277 (38), 35574-35585 (2002)
   PUBMED   12110693
REFERENCE   3  (bases 1 to 3272)
  AUTHORS   Kikuchi,K., Chedotal,A., Hanafusa,H., Ujimasa,Y., de Castro,F.,
            Goodman,C.S. and Kimura,T.
  TITLE     Cloning and characterization of a novel class VI semaphorin,
            semaphorin Y
  JOURNAL   Mol Cell Neurosci 13 (1), 9-23 (1999)
   PUBMED   10049528
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB000817.2.
            
            Sequence Note: This sequence has been modified as follows: removed
            16 bp suspected to be vector contamination from the 5' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB000817.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3272              AB000817.2         17-3288
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..3272
                     /gene="Sema6c"
                     /note="semaphorin 6C"
                     /db_xref="GeneID:29744"
                     /db_xref="RGD:3659"
     exon            1..149
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..2917
                     /gene="Sema6c"
                     /note="semaphorin-Y; Sema Y; sema domain, transmembrane
                     domain (TM), and cytoplasmic domain, (semaphorin) 6C"
                     /codon_start=1
                     /product="semaphorin-6C precursor"
                     /protein_id="NP_059004.1"
                     /db_xref="GeneID:29744"
                     /db_xref="RGD:3659"
                     /translation="MPRAPHSMPLLLLLLLSLPQAQTAFPQDPIPLLTSDLQGTSPSS
                     WFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTW
                     RSQDMENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGE
                     ELSGQARCPFDATQSTVAISAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSK
                     WLREPHFVYALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHW
                     TSFLKLRLNCSVPGDSTFYFDVLQSLTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFY
                     LDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAALFSSSQDLPDDVL
                     LFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVL
                     KVLPPGGQSLGPEPIILEEIDAYSHARCSGKRSPRAARRIIGLELDTEGHRLFVAFPG
                     CIVYLSLSRCARHGACQRSCLASLDPYCGWHRFRGCVNIRGPGGTDVDLTGNQESMEH
                     GDCQDGATGSQSGPGDSAYVLLGPGPSPETPSSPSDAHPGPQSSTLGAHTQGVRRDLS
                     PASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRRANRRRSKDIETPGLPRPLSL
                     RSLARLHGGGPEPPPPPKDGDAAQTPQLYTTFLPPPEGGSPPELACLPTPETTPELPV
                     KHLRASGGPWEWNQNGNNASEGPGRPRGCSAAGGPAPRVLVRPPPPGCPGQEVEVTTL
                     EELLRYLHGPQPPRKGSEPLASAPFTSRPPASEPGAALFVDSSPMPRDCVPPLRLDVP
                     PDGKRAAPSGRPALSAPAPRLGVSGSRRLPFPTHRAPPGLLTRVPSGGPSRYSGGPGR
                     HLLYLGRPDGHRGRSLKRVDVKSPLSPKPPLATPPQPAPHGSHFNF"
     exon            150..264
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            265..328
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            329..385
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            386..487
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            488..578
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            579..698
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            699..787
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1005
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1137
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1290
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1464
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1611
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1689
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1745
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1790
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1886
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..3272
                     /gene="Sema6c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtactccct ggggcttgag ctgccccgca caggatgccc cgtgcccccc actccatgcc
       61 cttgctgctg ctgttgctgc tgtcactccc ccaagcccag actgcctttc cccaggaccc
      121 catccctctg ttgacctctg acctacaagg tacctctccg tcatcctggt tccggggcct
      181 ggaggacgat gctgtggctg cggaacttgg gctggacttt cagagattcc tgaccttgaa
      241 ccggaccttg cttgtggctg cccgggatca cgttttctcc ttcgatcttc aagcccaaga
      301 agaaggggag gggctggtgc ccaacaagtt tctgacatgg cggagccaag acatggagaa
      361 ttgtgctgtc cggggaaagc tgacggacga atgctacaac tacatccgtg ttcttgttcc
      421 ctgggactcg cagacactcc ttgcctgtgg aacaaattcc ttcagccctg tgtgtcgcag
      481 ctatgggata acatctctgc aacaggaggg tgaggagctg agtgggcaag ctcgatgccc
      541 ctttgatgcc acccagtcca ctgtggccat ctctgcagag ggtagtttgt actcagccac
      601 agcagcagat ttccaggcca gtgatgctgt ggtttacaga agccttggac ctcagccccc
      661 actccgttct gcaaagtatg actccaagtg gcttcgagag ccacactttg tctatgcttt
      721 ggagcatgga gaccatgtct acttcttctt ccgagaagtc tctgtggagg acgcccgcct
      781 ggggagggtg cagttttccc gggtggcccg ggtgtgtaaa cgtgacatgg gtggctcacc
      841 acgggccttg gatcgccact ggacatcctt ccttaagctg aggctcaact gctccgtccc
      901 tggggactct accttctact ttgatgtctt acagtcctta actgggcctg tgaacctgca
      961 tgggcgctct gccctctttg gggtcttcac tactcagacc aatagcattc ctgggtctgc
     1021 agtctgcgcc ttctacctag atgacattga acgtggcttt gagggcaagt tcaaggagca
     1081 gaggagtctg gatggggcct ggactcctgt gtctgaggac aaagtcccct cacccaggcc
     1141 agggtcctgt gcaggtgtgg gtgcagctgc cttattctcc tcctctcaag acctgcctga
     1201 cgatgtcctg ctcttcatca aggcacaccc actgctggat cccgctgtgc cacctgccac
     1261 ccatcaacct ctcctcactc tgactagcag ggctctactg acccaggtag ctgtggatgg
     1321 tatggctggc ccccacagaa atactacagt cctgtttctt ggctccaatg atgggacagt
     1381 gctgaaggtg ctacctccag ggggacagtc tctgggaccc gagcctatca tattggaaga
     1441 gattgatgcc tacagccatg cccggtgcag tgggaagcgg tcaccccgag ctgctcgacg
     1501 gatcataggg ctggagctgg acactgaggg tcacaggctt tttgtggcct ttcctggatg
     1561 catcgtctac ctctctctca gccgctgtgc ccggcatgga gcatgtcaga ggagctgcct
     1621 ggcttctctg gacccatact gtggatggca tcggttccga ggctgtgtga atatcagggg
     1681 acctggaggg actgatgtgg atctgactgg gaaccaggaa tccatggagc atggtgactg
     1741 ccaagatgga gcgactggga gtcagtctgg ccctggagat tctgcctatg tgcttctggg
     1801 tcctggccct tcccctgaga cccccagttc ccccagtgat gcccacccag ggccccagtc
     1861 ttccactctt ggagctcaca ctcagggcgt gcgcagggac ctttccccag cctcagcctc
     1921 ccgatccatc cccatcccac tcctcctggc ctgtgtggcg gcggccttcg ctttgggcgc
     1981 ctcagtctcc ggcctcttgg tgtcctgtgc ttgtcgtcgc gcgaaccgcc gtcggagcaa
     2041 ggacatcgag accccggggc tgccgcgccc cctctccctt cgcagtctgg cgaggctgca
     2101 cggtggcggt cctgagcccc cgcctccgcc caaggatggt gatgcagcgc aaacgcccca
     2161 gctctacact accttcctgc ctccgcccga gggcggatcc ccaccggagc tggcctgcct
     2221 gcccaccccg gagaccacgc ccgagctgcc ggtgaagcac ctccgtgcct ccgggggtcc
     2281 ctgggagtgg aaccagaacg ggaacaacgc ttcggagggc ccaggccgcc cacggggctg
     2341 cagcgcggcg ggcgggcccg ccccgcgcgt gctggtgagg ccaccgcccc ctggctgccc
     2401 cgggcaggag gtggaggtga ccacgctgga ggaactgctg cgctacctgc acggcccgca
     2461 gccgcccagg aagggcagcg aacctctcgc ctccgccccg ttcacctccc ggccgcctgc
     2521 ctcggagccc ggcgccgcct tgttcgtgga ctccagcccg atgcctcgtg attgcgtgcc
     2581 gccgctgagg ctcgacgtac cgcccgacgg caagcgcgcg gccccgagcg ggcggcctgc
     2641 tctctcggcc ccggctccac gcctgggcgt cagcggcagc cgaagattgc ccttccccac
     2701 gcaccgggcg cccccgggcc tgctcacccg agtcccctcg ggaggcccgt ccaggtactc
     2761 cggggggccc gggaggcacc tcctgtacct gggccggccc gacggccacc gcggccgctc
     2821 cctgaagagg gtggacgtga agtctccact gtcgcccaaa ccgcccctcg ccacaccgcc
     2881 gcagcccgcc ccgcacggca gccattttaa cttctgacag aagctgctag cgcccgtcga
     2941 ggcgctggag gcctaggcct gcggaggccg ctggccttcc cggactccaa gagtctcccg
     3001 gggtcccctc tcgcctcggt ttatttattg actgtctttc cccctgtcct ttggcgagga
     3061 gctcgccgct cggagcgcca gcatttcagg ggacctggcc gactcccact ccccgctccc
     3121 ttccagccac gctgccttaa ctcgtcgctc cggactcccg cggactgggc cccgggcggg
     3181 ccggccgggg ctggagccgc gcgctgtgta cagagtcctc cggcctcctg gggccgggac
     3241 gtgcctcctc ctactgtgta ggagccccca cc
//
