LOCUS       NM_053471               3848 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus semaphorin 6B (Sema6b), mRNA.
ACCESSION   NM_053471
VERSION     NM_053471.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3848)
  AUTHORS   Suto,F., Ito,K., Uemura,M., Shimizu,M., Shinkawa,Y., Sanbo,M.,
            Shinoda,T., Tsuboi,M., Takashima,S., Yagi,T. and Fujisawa,H.
  TITLE     Plexin-a4 mediates axon-repulsive activities of both secreted and
            transmembrane semaphorins and plays roles in nerve fiber guidance
  JOURNAL   J Neurosci 25 (14), 3628-3637 (2005)
   PUBMED   15814794
REFERENCE   2  (bases 1 to 3848)
  AUTHORS   Kikuchi,K., Ishida,H. and Kimura,T.
  TITLE     Molecular cloning of a novel member of semaphorin family genes,
            semaphorin Z
  JOURNAL   Brain Res Mol Brain Res 51 (1-2), 229-237 (1997)
   PUBMED   9427525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000204.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by NM_053471.4.
            
            On Feb 10, 2021 this sequence version replaced NM_053471.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB000776.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-336               JACYVU010000204.1  707933-708268       c
            337-460             JACYVU010000204.1  707706-707829       c
            461-521             JACYVU010000204.1  706912-706972       c
            522-584             JACYVU010000204.1  706714-706776       c
            585-686             JACYVU010000204.1  706289-706390       c
            687-777             JACYVU010000204.1  705892-705982       c
            778-897             JACYVU010000204.1  705195-705314       c
            898-986             JACYVU010000204.1  704631-704719       c
            987-1204            JACYVU010000204.1  703598-703815       c
            1205-1336           JACYVU010000204.1  702835-702966       c
            1337-1486           JACYVU010000204.1  702290-702439       c
            1487-1669           JACYVU010000204.1  701803-701985       c
            1670-1819           JACYVU010000204.1  701568-701717       c
            1820-1897           JACYVU010000204.1  701103-701180       c
            1898-1956           JACYVU010000204.1  700919-700977       c
            1957-3848           JACYVU010000204.1  698628-700519       c
FEATURES             Location/Qualifiers
     source          1..3848
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3848
                     /gene="Sema6b"
                     /note="semaphorin 6B"
                     /db_xref="GeneID:84609"
                     /db_xref="RGD:69278"
     exon            1..336
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     CDS             213..2876
                     /gene="Sema6b"
                     /note="sema Z; semaphorin-Z; sema domain, transmembrane
                     domain (TM), and cytoplasmic domain, (semaphorin) 6B"
                     /codon_start=1
                     /product="semaphorin-6B precursor"
                     /protein_id="NP_445923.1"
                     /db_xref="GeneID:84609"
                     /db_xref="RGD:69278"
                     /translation="MWTPRAPPPRPALLFLLLLLLRVTHGLFPDEPPPLSVAPRDYLS
                     HYPVFVGSGPGRLTPAEGAEDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTELRYQ
                     RKLTWRSNPSDIDVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPICANYSMD
                     TLQLLGDNISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLR
                     TVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSP
                     RVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVILAVFSTPSNSIPG
                     SAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASNAL
                     PDEILNFVKTHPLMDEAVPSLGHSPWIVRTLIRHQLTRVAVDVGAGPWGNQTIVFLGS
                     EVGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRSSSAGEWGQRLLSLELDAA
                     SGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPDGSCIFLRPGTSATFE
                     QDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFV
                     GLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGTGGRGGAGGGPGGPPEALL
                     APLMQNGWTKAALLHGGPHDLDSGLLPTPEQTPLPQKRLPTTHPHAHALGPRAWDHSH
                     ALLSASASTSLLLLAHTRAPEQPPVPTESGPESRLCAPRSCRASHPGDFPLTPHASPD
                     RRRVVSAPTGPLDSSSVGDDLPGPWSPPATSSLRRPGPHGPPTAALRRTHTFNSGEAR
                     PGGHRPRRHAPADSTHLLPCGTGERTAPPVP"
     exon            337..460
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            461..521
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            522..584
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            585..686
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            687..777
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            778..897
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            898..986
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1204
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1336
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1486
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1669
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1819
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1897
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..1956
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..3848
                     /gene="Sema6b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttcctgag aattttatgc acatgtggtc ttaaagtcgc ttgttaatta aacaacctct
       61 gagcgtcatt attattatca atgttattat ttttattctg gaggaagaga gggactcgcg
      121 cgccccctaa tggcctctta tggaactgca ggaagctcca ctcactggcc ttctggcttg
      181 taggtgttac ctgtggtcac ctggtcctca ccatgtggac cccgcgagcg ccccctccac
      241 gcccggccct gctgttcctc ctgctgttgc ttctgagggt cacccatggc cttttcccag
      301 atgaaccacc tccactcagt gtggctccca gggactacct gagccactac cccgtgttcg
      361 tgggcagcgg gcctggtcgt ctgacccctg cagagggtgc tgaggacctc aacatccaga
      421 gagtgctacg tgttaacagg acactgttca tcggggacag agacaacctg taccaagtag
      481 aactggagcc atccacatcc acggagctgc ggtatcagcg gaagcttacc tggcgctcca
      541 accccagtga catcgatgtg tgtcggatga agggcaagca agagggtgag tgtcggaact
      601 ttgtcaaggt gctcctgctt cgtgacgaat ccacgctctt cgtgtgcggc tccaatgcat
      661 tcaatcccat ctgtgccaat tacagtatgg acacactgca gcttcttgga gacaacatca
      721 gtggtatggc ccgctgcccc tacgacccca agcatgccaa tgtcgccctc ttctcagatg
      781 ggatgctctt cacagccaca gtaactgact tcctagccat cgacgctgtt atctaccgta
      841 gccttgggga ccggcccaca ctgcgcacag taaagcatga ctccaagtgg tttaaagagc
      901 catactttgt gcatgcggtg gagtggggaa gccacgtcta cttcttcttc cgggagatcg
      961 ccatggagtt taactatctg gaaaaggtgg tggtgtcccg tgtggcccgt gtatgcaaga
     1021 atgatgtggg cggctcccca cgggtgctgg agaagcagtg gacttccttc ctgaaggccc
     1081 ggctcaactg ctccgtgcct ggggactcac acttctactt caatgtactg caggctgtga
     1141 ctggtgtggt gagccttggc ggccgtccag tgattcttgc tgtcttctca actcctagca
     1201 acagcatccc tggctcagct gtctgtgcct ttgacatgaa ccaagtggct gctgtgtttg
     1261 aaggccgctt ccgggagcag aagtcacctg agtcaatctg gaccccagtg cctgaggacc
     1321 aagtaccacg gcccaggccc gggtgctgtg cagcgcccgg tatgcagtac aacgcatcca
     1381 atgcccttcc tgacgagatt ctcaactttg taaagaccca cccactgatg gacgaagcgg
     1441 tgccctccct gggccactcg ccttggattg tgagaactct gatacggcac cagctgaccc
     1501 gagtggctgt ggatgtgggt gcaggcccat ggggcaatca gacaatagtc ttccttggct
     1561 ctgaggttgg cacagtcctc aaattccttg tgaagcccaa tgccagtgtc tcagggacca
     1621 cagggcccag catctttttg gaggagtttg agacctaccg gccagacagg tgtggacgat
     1681 ccagcagtgc tggtgagtgg ggacaacgac ttctgagcct ggagctagat gctgcctcag
     1741 gtggcctgct ggcagccttc ccccgctgtg tggttcgtgt tcctgttgcc cgctgccagc
     1801 tgtactcggg gtgcatgaag aactgcattg gcagccaaga tccatactgc gggtgggccc
     1861 ccgatggctc ctgcatcttc ctcagaccag gaaccagtgc cacgtttgag caagatgtgt
     1921 ccggggccag cacctctggc ttaggtgact gcactggact cttgcgcgcc agcctctcag
     1981 atgaccgcgc agggctggta tcggtgaacc tgctggtgac gtcctcggtg gcagcgttcg
     2041 tggtgggtgc cgtggtgtcc ggtttcagcg tgggctggtt cgtgggtctc cgcgagcggc
     2101 gggagctggc ccggcgcaag gacaaggaag ccatcctggc gcatggcggc agcgaggcag
     2161 tgctgagcgt gagccgactg ggcgagcgca ggggaaccgg gactgggggt cgtgggggag
     2221 ccggcggcgg tcccgggggt cccccggagg ccctgctggc cccgcttatg cagaatggct
     2281 ggacaaaggc ggcactgctg catggtggtc ctcacgacct ggattcgggg ctgctgccca
     2341 cccctgagca gacgcctctg ccccagaaac gcctgcccac aacacaccca cacgcccacg
     2401 ccctaggacc gcgagcctgg gaccacagcc acgcgctgct gtcggcctct gcctccacat
     2461 ccttgctcct gctggcgcac acccgcgccc ctgagcagcc cccagtgccg actgagtcag
     2521 gcccggaatc tcgcctctgc gccccaagat cctgccgggc ctctcaccca ggcgacttcc
     2581 cactcacgcc tcacgccagc ccggaccgcc ggcgggttgt gtccgcaccc acgggcccct
     2641 tggactcttc ttcggtgggc gacgaccttc cagggccatg gagcccacct gcaaccagca
     2701 gcctgcggag gccgggcccc catgggcccc caacagccgc cctgcggcgc acacacacat
     2761 tcaacagcgg cgaggcgagg cccgggggtc accgtcctcg ccgccacgca cccgcggact
     2821 ctacacactt gctgccctgc gggacgggcg agcggactgc acccccggta ccctaggccg
     2881 ggcggatgcc tcgacggtgc caaccacagc gacccgggcg tcagcccagg tcaccgagcc
     2941 ctactggcgc cgagtgggac gcgttcgttc cccaccctcg cgggtgggga tctcctcgcc
     3001 acagggaagc acaagagccc cctccatccc ggaagatgca gaacatgaag ccccggggtg
     3061 ggcgggaaga ggctgacctt ttacctgagc atagactttg atttttgttt attttgagtt
     3121 tggttttttt tttttttcta agaaattgca cagccccatt cttacttggg gtgtcggccg
     3181 gggtgggagg tgaggatatg gggtaacggg aggcagagct gcagacacga gccttcctgc
     3241 ctcaacacat cctccctaga agggaccccc tcccctttcc tgggctcctg cgcgcgcgcg
     3301 cgcgcgcgcg cgtgtgtgtg tgtgtgtgtg tgtgtgtgtc cgtgtgcatg gcctgtttgt
     3361 gtgcaaaggc ccgaggcaga agtatgtgtg cgtgcgtgtg agacagggct gccgtgtgtg
     3421 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgcg actcagaatg tgggtggtgg
     3481 tgccctcaga gaccctggca ttggctgagc caatgttggt acttctggaa agaaacccag
     3541 gggatggagc ctctgaggtg ccggttggag ttcaaatcct gctcctgcag agggaatctg
     3601 gggatccagg ctgggagatg ggggaaccta cttctaaagg gcttgtgggg ggttttggga
     3661 gggtggaagt gggcagacac ccctgtaaat acagccctgg ggtggtcaga gaggcccatg
     3721 ccacctgtcc ccacttgtga catgccctct gactgccaac tgaccatgca tgccacgtgg
     3781 ccagctgagt ccaggaccct cctcagccct atccctgtca ataaaactct tgtttacatc
     3841 caccggcc
//
