LOCUS       NM_001170462            3437 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus semaphorin 4B (Sema4b), mRNA.
ACCESSION   NM_001170462 XM_001065817 XM_001065984
VERSION     NM_001170462.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3437)
  AUTHORS   Burkhardt,C., Muller,M., Badde,A., Garner,C.C., Gundelfinger,E.D.
            and Puschel,A.W.
  TITLE     Semaphorin 4B interacts with the post-synaptic density protein
            PSD-95/SAP90 and is recruited to synapses through a C-terminal
            PDZ-binding motif
  JOURNAL   FEBS Lett 579 (17), 3821-3828 (2005)
   PUBMED   15978582
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001170462.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098793.1, SRR21887623.2398912.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               JAXUCZ010000001.1  143558797-143558974
            179-342             JAXUCZ010000001.1  143573320-143573483
            343-405             JAXUCZ010000001.1  143573755-143573817
            406-504             JAXUCZ010000001.1  143576226-143576324
            505-616             JAXUCZ010000001.1  143576971-143577082
            617-730             JAXUCZ010000001.1  143577366-143577479
            731-882             JAXUCZ010000001.1  143577585-143577736
            883-1064            JAXUCZ010000001.1  143579620-143579801
            1065-1215           JAXUCZ010000001.1  143579927-143580077
            1216-1426           JAXUCZ010000001.1  143580845-143581055
            1427-1542           JAXUCZ010000001.1  143581165-143581280
            1543-1709           JAXUCZ010000001.1  143581515-143581681
            1710-1792           JAXUCZ010000001.1  143584784-143584866
            1793-3437           JAXUCZ010000001.1  143585393-143587037
FEATURES             Location/Qualifiers
     source          1..3437
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..3437
                     /gene="Sema4b"
                     /note="semaphorin 4B"
                     /db_xref="GeneID:293042"
                     /db_xref="RGD:1307872"
     exon            1..178
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..2532
                     /gene="Sema4b"
                     /note="sema domain, immunoglobulin domain (Ig),
                     transmembrane domain (TM) and short cytoplasmic domain,
                     (semaphorin) 4B"
                     /codon_start=1
                     /product="semaphorin-4B precursor"
                     /protein_id="NP_001163933.1"
                     /db_xref="GeneID:293042"
                     /db_xref="RGD:1307872"
                     /translation="MGRASRSADLLSALQLLLLLLRTTTARALGPRISVPLDSEERLI
                     RKFEAENISNYTALLLSQDGKTLYVGAREALFALNSNLSFLPGGEYQELLWSADPDRK
                     QQCSFKGKDPKRDCQNYIKILLPLNSSHLLTCGTAAFSPLCAYINTASFTLARDEAGS
                     VLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSPRPTKTESSLN
                     WLQDPAFVASAYVPESLGSPIGDDDKIYFFFSETGQEFEFFENTIVSRVARVCKGDEG
                     GERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLNPNPQDWRKTLFYGVFTSQWH
                     RGTTEGSAICVFTMNDVQKAFDGLYKKVNRETQQWYTETHPVPTPRPGACITNSARER
                     KINSSLQLPDRVLNFLKDHFLMDGQVRSRLLLLQPQARYQRVAVHRVPGLHSTYDVLF
                     LGTGDGRLHKAVTLDSRVHIIEELQVFPQGQPVQNLLLDSHGGLLYASSHSGVVQVPV
                     ANCSLYPTCGDCLLARDPYCAWNGSTCKLLSLYQPDLASRPWIQDIEGANTKELCNIS
                     SAKARSFKPGKPCKQVQIQANTVNTLACPLLSNLATRLWLHNGAPVNASASCRVLPSG
                     DLLLVGSQQGLGVFQCWSIEEGFRQLVASYCPEVKEDGVMDQNDQSDGTPVIINTSRV
                     SAPAGGRASWGADKSYWNEFLVMCTLFGLAVVLLVLFFLYRNRDGMKLFLKQGECASV
                     HPKTRPAVLPPETRPLNGVGPPSTPLDHRGYQALSDSSPGPRVFTESEKRPLSIQDSF
                     VEVSPVCPRPRVRLGSEIRDSVV"
     exon            179..342
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            343..405
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            406..504
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            505..616
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            617..730
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            731..882
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1064
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1215
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1426
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1542
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1709
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1792
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..3437
                     /gene="Sema4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actccacttg agcaacctga gccggaggac gccgctcctg ccgcggtccg agctccacgc
       61 gccgcgatgg gccgggcgag ccgctccgcc gacctgctga gcgcgctgca gctgctgttg
      121 ctactgctgc ggacgacgac ggcgcgggcg ctcggcccac ggatcagtgt gccgctggac
      181 tctgaagaaa ggctgattag aaaatttgaa gctgaaaaca tctccaacta cacggccctt
      241 ctgctgagcc aagatggcaa gacgctgtat gtgggggccc gagaggccct ctttgccctt
      301 aacagcaacc tcagcttctt gccgggcggg gagtaccaag agctgctgtg gagtgcagat
      361 cctgacagga agcagcagtg cagcttcaag ggcaaggacc caaagcgtga ctgtcaaaac
      421 tacatcaaga tccttctgcc cctcaacagc agccatctgc tcacctgtgg caccgcagcc
      481 ttcagccccc tgtgtgctta cattaacaca gcaagcttta cattagcccg agacgaggct
      541 ggcagtgtcc tcctagagga tggcaagggc cggtgtccct ttgaccccaa cttcaagtcc
      601 acggctctgg tggttgatgg tgagctgtac actggaacag tcagtagctt ccagggaaac
      661 gacccagcca tttcccggag ccagagtccc cgccccacca agactgagag ctccctcaac
      721 tggctgcaag accctgcctt tgtggcctca gcctatgttc ctgagagcct gggcagccca
      781 ataggtgatg atgataagat ctacttcttc ttcagcgaga cgggccagga gtttgagttc
      841 tttgagaaca ccattgtctc cagagttgcc cgagtctgta agggcgatga gggtggagag
      901 cgggtgttgc agcagcgctg gacttccttc ctcaaggctc agctcctgtg ctcccggccc
      961 gatgatggct ttccctttaa cgtgctacaa gatgtcttca ccctgaaccc caaccctcag
     1021 gactggcgca agaccctttt ctatggggtc tttacctccc agtggcacag agggaccaca
     1081 gaaggctctg ccatctgcgt cttcaccatg aatgacgtgc agaaggcctt tgatggtctg
     1141 tataagaaag tgaacagaga gacacagcag tggtatactg agacccaccc agtgcccact
     1201 ccccggccgg gagcgtgtat caccaacagt gcccgggaac ggaagatcaa ctcgtcgctg
     1261 cagctcccgg accgagtgct gaacttcctc aaggatcact tcttgatgga tgggcaggtc
     1321 cgcagccgcc tgctgctgct ccagccacaa gcccgctacc agcgtgtggc cgtgcaccga
     1381 gtgcctggcc tgcacagcac gtatgatgta ctatttctgg gcactggtga tggtcgcctg
     1441 cacaaggcag tgaccctgga ctccagagtg cacatcattg aggagctgca ggtcttccct
     1501 caaggacagc ctgtgcagaa cctgctcttg gacagccatg ggggactgtt gtatgcctcc
     1561 tcccattctg gggtagtgca agtgcccgta gccaactgca gcctgtaccc aacctgtgga
     1621 gactgcctcc tggctcgaga cccttactgc gcctggaacg gctccacctg caagctcctt
     1681 agtctctacc agcctgatct ggcctccagg ccatggatcc aggatattga gggtgccaat
     1741 accaaggaac tctgcaatat ttcctcagcc aaggcccggt cttttaagcc aggtaagcca
     1801 tgtaaacaag tccagatcca agcaaacaca gtgaacaccc tggcctgccc actcctctca
     1861 aacctggcta ctcggctctg gctgcacaat ggggctcctg tcaatgcttc tgcctcctgc
     1921 cgggtgttac ccagtgggga cctgctgctg gtaggcagcc agcagggctt gggggtgttc
     1981 cagtgttggt ccatagaaga aggattccgg cagctggtgg ccagctactg cccagaggtg
     2041 aaggaggatg gagtaatgga ccaaaatgac cagagtgatg gcaccccggt cattatcaac
     2101 acatcacgag tgagtgcacc tgctggtggc agggccagct ggggtgcaga caagtcatac
     2161 tggaatgaat tcctggtgat gtgtactctg tttgggcttg ctgtggtgct tctggttctg
     2221 ttctttctct accgaaatcg ggatggcatg aagctcttcc taaagcaggg cgaatgtgcc
     2281 agtgtgcacc ccaagactcg ccctgcagtg ctcccacctg agacccgacc actcaatggt
     2341 gttggccctc ccagcacccc ccttgaccac cgaggctacc aggctctgtc ggatagctcc
     2401 ccagggcccc gagtctttac tgagtcagag aagaggccac tgagtatcca ggacagcttt
     2461 gtggaggtgt ctcctgtgtg tccccggccc cgagttcgac tgggctctga gatccgagac
     2521 tctgtggtat gagaactgac tttagatgta gccaccctga cctcaggggc tgtgaatgtt
     2581 cagtggaggt cagctacctc tgctgtcaca gaacacaacc atggtaccct gcctgggagg
     2641 cagctggtat cacagcacca acagcctggc cagccggttc caatgtctgg ccgaaaaggg
     2701 ctgcctccag gggccagagg gtccctgtct ggatggcaga actctgctac ttaactgagc
     2761 cctttgttta aaactgcaaa tgtgaagcca gagagagagg aaggagagat agataaggaa
     2821 gactgtacgg cacagccact ccaattcagc ctgctgggct cttggggact tctctgaagt
     2881 ggctttgtga gctggagttg ggaatccctc ccccactgga ctattcattc taccttccgc
     2941 cttactccgc tgctgaggcc actgcagaat cagggccctg ctccagcttc agccaaccaa
     3001 ggacatgtct gtgaccgctg acaccccacc acctcaggga ctagagggct aggctggctc
     3061 tgcagccctc ctcaccagac cctgggctca gtcccagttc ccagacttct ccagcctgta
     3121 tcaggctgtg gcctggaaag caagggagtg accccagggg gcgttgtgac agaagactgt
     3181 tgcctgctgt ccttttccca gttgaggaac tgtgtcgcca cccacctcat cagccctgtt
     3241 ttctaattcc aacacagact tctggatcct ccctgttccc tgtcctagct caccatgccc
     3301 ttgcccacca ctctaaggga tactgacact gcccatcacg aggaccctga atttacatgg
     3361 gttttgtatt ttttttttaa taagatgcac tttactttct tttttttttt aaataaagtc
     3421 cagcaaatta tagttaa
//
