LOCUS       NM_001413830            3866 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus semaphorin 3F (Sema3f), mRNA.
ACCESSION   NM_001413830 XM_039081589
VERSION     NM_001413830.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3866)
  AUTHORS   Ko,J.A., Minamoto,A., Sugimoto,Y. and Kiuchi,Y.
  TITLE     Down-regulation of semaphorin 3F in rat retinal ganglion cells in
            response to optic nerve crush
  JOURNAL   Cell Biochem Funct 34 (5), 378-384 (2016)
   PUBMED   27309587
  REMARK    GeneRIF: Sema3F may contribute to the regulation of retinal
            ganglion cell function or survival.
REFERENCE   2  (bases 1 to 3866)
  AUTHORS   Demyanenko,G.P., Mohan,V., Zhang,X., Brennaman,L.H., Dharbal,K.E.,
            Tran,T.S., Manis,P.B. and Maness,P.F.
  TITLE     Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced
            dendritic spine remodeling
  JOURNAL   J Neurosci 34 (34), 11274-11287 (2014)
   PUBMED   25143608
REFERENCE   3  (bases 1 to 3866)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   4  (bases 1 to 3866)
  AUTHORS   Xiang,X., Zhang,X. and Huang,Q.L.
  TITLE     Plexin A3 is involved in semaphorin 3F-mediated oligodendrocyte
            precursor cell migration
  JOURNAL   Neurosci Lett 530 (2), 127-132 (2012)
   PUBMED   23063687
  REMARK    GeneRIF: These results suggest that plexin A3 is expressed in OPCs
            and immature oligodendrocytes and is involved in OPC migration.
REFERENCE   5  (bases 1 to 3866)
  AUTHORS   Yang,G., Qu,X., Zhang,J., Zhao,W. and Wang,H.
  TITLE     Sema3F downregulates p53 expression leading to axonal growth cone
            collapse in primary hippocampal neurons
  JOURNAL   Int J Clin Exp Pathol 5 (7), 634-641 (2012)
   PUBMED   22977659
  REMARK    GeneRIF: These data reveal a novel mechanism by which Sema3F can
            induce hippocampal neuron growth cone collapse.
REFERENCE   6  (bases 1 to 3866)
  AUTHORS   Suto,F., Ito,K., Uemura,M., Shimizu,M., Shinkawa,Y., Sanbo,M.,
            Shinoda,T., Tsuboi,M., Takashima,S., Yagi,T. and Fujisawa,H.
  TITLE     Plexin-a4 mediates axon-repulsive activities of both secreted and
            transmembrane semaphorins and plays roles in nerve fiber guidance
  JOURNAL   J Neurosci 25 (14), 3628-3637 (2005)
   PUBMED   15814794
REFERENCE   7  (bases 1 to 3866)
  AUTHORS   Tamamaki,N., Fujimori,K., Nojyo,Y., Kaneko,T. and Takauji,R.
  TITLE     Evidence that Sema3A and Sema3F regulate the migration of GABAergic
            neurons in the developing neocortex
  JOURNAL   J Comp Neurol 455 (2), 238-248 (2003)
   PUBMED   12454988
REFERENCE   8  (bases 1 to 3866)
  AUTHORS   Dionne,M.S., Brunet,L.J., Eimon,P.M. and Harland,R.M.
  TITLE     Noggin is required for correct guidance of dorsal root ganglion
            axons
  JOURNAL   Dev Biol 251 (2), 283-293 (2002)
   PUBMED   12435358
REFERENCE   9  (bases 1 to 3866)
  AUTHORS   Cheng,H.J., Bagri,A., Yaron,A., Stein,E., Pleasure,S.J. and
            Tessier-Lavigne,M.
  TITLE     Plexin-A3 mediates semaphorin signaling and regulates the
            development of hippocampal axonal projections
  JOURNAL   Neuron 32 (2), 249-263 (2001)
   PUBMED   11683995
REFERENCE   10 (bases 1 to 3866)
  AUTHORS   Chedotal,A., Del Rio,J.A., Ruiz,M., He,Z., Borrell,V., de
            Castro,F., Ezan,F., Goodman,C.S., Tessier-Lavigne,M., Sotelo,C. and
            Soriano,E.
  TITLE     Semaphorins III and IV repel hippocampal axons via two distinct
            receptors
  JOURNAL   Development 125 (21), 4313-4323 (1998)
   PUBMED   9753685
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 9, 2022 this sequence version replaced XM_039081589.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.37079.1,
                                           SRR21887620.490205.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-534               JAXUCZ010000008.1  117264673-117265206 c
            535-695             JAXUCZ010000008.1  117260677-117260837 c
            696-856             JAXUCZ010000008.1  117247659-117247819 c
            857-919             JAXUCZ010000008.1  117247492-117247554 c
            920-1039            JAXUCZ010000008.1  117247271-117247390 c
            1040-1132           JAXUCZ010000008.1  117246433-117246525 c
            1133-1226           JAXUCZ010000008.1  117244764-117244857 c
            1227-1346           JAXUCZ010000008.1  117243342-117243461 c
            1347-1486           JAXUCZ010000008.1  117243004-117243143 c
            1487-1601           JAXUCZ010000008.1  117242794-117242908 c
            1602-1671           JAXUCZ010000008.1  117242558-117242627 c
            1672-1816           JAXUCZ010000008.1  117242269-117242413 c
            1817-2039           JAXUCZ010000008.1  117240633-117240855 c
            2040-2128           JAXUCZ010000008.1  117239994-117240082 c
            2129-2170           JAXUCZ010000008.1  117239440-117239481 c
            2171-2328           JAXUCZ010000008.1  117239114-117239271 c
            2329-2396           JAXUCZ010000008.1  117238893-117238960 c
            2397-2530           JAXUCZ010000008.1  117238472-117238605 c
            2531-3866           JAXUCZ010000008.1  117236269-117237604 c
FEATURES             Location/Qualifiers
     source          1..3866
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..3866
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /note="semaphorin 3F"
                     /db_xref="GeneID:315996"
                     /db_xref="RGD:1308514"
     exon            1..534
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            535..695
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     CDS             584..2941
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /note="semaphorin IV; sema domain, immunoglobulin domain
                     (Ig), short basic domain, secreted, (semaphorin) 3 F"
                     /codon_start=1
                     /product="semaphorin-3F precursor"
                     /protein_id="NP_001400759.1"
                     /db_xref="GeneID:315996"
                     /db_xref="RGD:1308514"
                     /translation="MLVTGFILWASLLTGAWPAAPIQDQLPATPRVRLSFKELKATGT
                     AHFFNFLLNTTDYRILFKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIE
                     ECILSGKDGNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRSQAPPWTQMQ
                     VVRGRGSRATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEEL
                     YAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLY
                     FFFRERSAEAPQNPAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIET
                     HFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEG
                     PNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPLQR
                     RPLVVRTGAPYRLTTVAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQEVEELML
                     EEVEVFKEPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYC
                     AWDGQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAIESVQYGVAGSAAFL
                     ECQPRSPQATVKWLFQRDPSDRRREIRAEDRFLRTEQGLLLRALQLGDRGLYSCTATE
                     NNFKHVVTRVQLHVLGRDAVHAALFPPLAVSVPPPPGTGPPTPPYQELAQLLAQPEVG
                     LIHQYCQGYWRHVPPNPREAPGALRPPELQDQKKPRNRRHHPPDT"
     exon            696..856
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            857..919
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1039
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1132
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1226
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1346
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1486
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1601
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1671
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1816
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..2039
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2128
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2170
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2328
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2396
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2530
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
     exon            2531..3866
                     /gene="Sema3f"
                     /gene_synonym="SemaIV"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgtcctg tcccgccagc ggcctcgaga cccgagcagc tagggaacaa accgcagcgg
       61 tccagggagc cccgagcgca gcgtagagcc agggtacgct tcgaggaccc gcgcagcccc
      121 gctcggtctc cgggccctag tcaggcaagc gcagcaccac ccggccgagc acagcgcagc
      181 gctccgtagc ctagcgcgcg ccgccgcccg cgccccgcac cggggaatgc gccctcggcg
      241 cgcaggccag ggggcgcccg cagcccgccc caggggaggc ggccccgagc gcccctgagc
      301 ctttccatgg cccgggctag ggcccggggc ctcggctgct gacgtgcacg aagccagggg
      361 aaccagtgaa gccgagaccg cggtgcggat cccggctcag gctcagagac aagagggcgc
      421 ggacagggcc gtggccccgg ggggcagcta aagcggaccg gccggacgcg gacctcttcg
      481 ctgctgcggc ggccaccgct gcccgggcgc ccaggccccg tcgccgtgga cgaggtgtcc
      541 acagagctgg agcctgcttc ctgggcccca ggcccctccc acaatgcttg tcactggctt
      601 catcctctgg gcttccctgc tgactggggc ctggccagct gcccccatcc aggaccagct
      661 tccagccaca cccagagtcc gactatcttt caaagaactt aaggccacag gtactgccca
      721 cttcttcaac tttctgctca acactacaga ctacagaatc ctgttcaagg acgaggacca
      781 tgaccgcatg tatgtgggca gcaaggacta cgtgctgtcc ctggacctgc atgacatcaa
      841 ccgagagccc cttattatcc actgggcagc ctccccacag cgcattgagg agtgcatatt
      901 gtcaggcaag gatggcaacg gagagtgtgg gaacttcgtc agactcatcc agccctggaa
      961 ccggacacac ctgtacgtgt gcgggaccgg tgcctacaac cccatgtgca cctatgtgaa
     1021 ccgtggccgt cgctcacagg ccccaccgtg gacccagatg caggtggtca gaggccgagg
     1081 cagcagggcc acagatggtg ccgaccgccc gacgcccaca gccccacgcc aggattacat
     1141 cttctacctg gagcctgaga aacttgagtc agggaaaggc aaatgcccat acgaccccaa
     1201 gctggacacg gcctcagccc tcatcaatga ggagctctac gcaggagtgt acatcgattt
     1261 tatgggcact gatgcagcca ttttccgtac gcttggaaag cagacagcca tgcgcacaga
     1321 tcagtacaac tcccggtggc tcaatgatcc ttcattcata catgctgagc tcatccctga
     1381 cagcgctgag cgcaacgacg ataaactcta cttcttcttc cgagagcgct ctgcagaggc
     1441 tccgcagaac cctgcggtgt acgcccgcat cgggcgcatc tgcctcaacg atgacggtgg
     1501 ccattgctgc ctggtcaaca agtggagcac attcctgaag gcacggctcg tctgctctgt
     1561 gccaggcgag gatggcattg agacccactt cgatgaactc caggacgtgt ttgtccagca
     1621 gacccaggac gtcaggaacc cagtcattta tgctgtcttc acctcttcag gctctgtgtt
     1681 ccgaggatct gcagtgtgtg tctactctat ggctgacatc cgcatggtct tcaatgggcc
     1741 ttttgctcac aaggagggcc ccaactacca gtggatgcct ttctcaggaa agatgccgta
     1801 tccccggcct ggcacatgcc ctggtggaac ctttacgcca tcgatgaagt ccaccaagga
     1861 ctatcctgat gaagtgatca acttcatgcg tactcatcca ctcatgtacc aggccgtcta
     1921 cccgctgcag cggcgccccc tggtggtccg tacaggcgct ccctaccgcc tcaccactgt
     1981 cgctgtggac caggtggatg cagctgatgg acgctatgag gtgcttttcc tgggcacaga
     2041 ccgcgggaca gtgcagaagg tcatcgtgct gcccaaggat gatcaggagg tggaagagct
     2101 catgttagag gaggtggagg tcttcaagga gccagcacct gttaaaacta tgaccatctc
     2161 ttccaagagg caacaactgt atgtggcctc cgccgtgggc gtcacacacc tgagcctgca
     2221 ccgctgtcag gcctatggag ctgcctgtgc tgactgctgc ctcgcccgag atccctactg
     2281 tgcctgggat ggccaggcct gctctcgcta cacagcatcc tccaagaggc ggagtcgccg
     2341 acaagatgtc cgccacggga accccatcag gcagtgccgt ggtttcaatt ccaatgcaaa
     2401 caagaatgcc atagagtctg tgcagtacgg cgtggccgga agtgcggctt tccttgagtg
     2461 ccagcctcgg tcacctcaag ccactgttaa gtggcttttc cagcgagatc ccagtgatcg
     2521 gcgtcgtgag attcgcgcag aggaccgctt cctgcgcaca gagcaggggc tgttgcttcg
     2581 cgccctgcag cttggtgacc gcggcctcta ctcctgcacg gccactgaga acaacttcaa
     2641 gcacgtcgtc acgcgggtac agctgcatgt actgggccgg gacgccgtcc atgctgccct
     2701 cttcccccca ctggctgtga gcgtccctcc acctcctggc acaggccctc caacacctcc
     2761 ttaccaggag ctggcccagc tcctagccca accggaagtg ggcctcatcc atcagtactg
     2821 ccagggttac tggcgccatg tgccccccaa ccccagggag gctccaggag ctctcaggcc
     2881 tcctgaactc caggaccaga aaaagccgag gaaccgccgc caccatcctc cggacacatg
     2941 aggccagctg ctggaggcct acataggacc agcctagccc ctcatccctt ttaatataaa
     3001 agatatatat atatataaat ataaaatatc tatattctat acataccctg cccctgcaaa
     3061 gacagtattt attggtgggt tgtatatagc ctgcctgggt ggcagcatta ttccagaact
     3121 tagacccaga ttggtcagca acggcacatg actgagcacg cccatcctgg cctagggagt
     3181 tgccagggcc accccaagac cacacagtcc ccagactccg tggaaatctc cttgctgaac
     3241 agctgccaag ttctacaaaa cacagggagg gagcgagccc tacttgtggg ggcatggacc
     3301 ataaaccttt ggtgacgagc attgtcagct gtgccttggc atagacgcgg acaccgggat
     3361 tgctctggag tctggggcgg gggctcaggg cactcagagg cgggagaagg gggccatcac
     3421 aggatatagg cccctgcctg ggtcagaggt gcccagtcaa ggccaatctt tcccaggtat
     3481 ttattctcta tttattgggg acagaagaga agtctgtctg ggtgaggcag aaccttctct
     3541 tctcccttcc ttccttgcct gtcctggaag gtccagccta ttctacctcc ttagctttgc
     3601 ctgtgctgcc ccaacgcacg ggcggggctg ggtgcaggca tggttttaaa gaacccccag
     3661 tcctgaggat agatgggcca tggtggaggc ccagggcctg tctgacatcc ccaaggctca
     3721 cgtctgccca ctgccacagg tgatgggtgt aaatagctct ggtggcagtg gcgtagatgg
     3781 ttggggggct cctgcagcct ctgctgccca ggccgcagtc tctcttgggt tccatcttgc
     3841 taataaacgc tggctctggg actaga
//
