LOCUS       NM_019177               1578 bp    mRNA    linear   ROD 21-JAN-2025
DEFINITION  Rattus norvegicus selectin L (Sell), mRNA.
ACCESSION   NM_019177
VERSION     NM_019177.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1578)
  AUTHORS   Liu,C.M., Chen,J., Yang,S., Mao,L.G., Jiang,T.T., Tu,H.H.,
            Chen,Z.L., Hu,Y.T., Gan,L., Li,Z.J. and Li,J.C.
  TITLE     The Chinese herbal formula Zhibai Dihuang Granule treat
            Yin-deficiency-heat syndrome rats by regulating the immune
            responses
  JOURNAL   J Ethnopharmacol 225, 271-278 (2018)
   PUBMED   29729385
REFERENCE   2  (bases 1 to 1578)
  AUTHORS   Mehta-D'souza,P., Klopocki,A.G., Oganesyan,V., Terzyan,S.,
            Mather,T., Li,Z., Panicker,S.R., Zhu,C. and McEver,R.P.
  TITLE     Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to
            Stabilize the High Affinity State under Force
  JOURNAL   J Biol Chem 292 (6), 2510-2518 (2017)
   PUBMED   28011641
REFERENCE   3  (bases 1 to 1578)
  AUTHORS   Chiang,Y.J., Ho,K.C., Sun,C.T., Chiu,J.J., Lee,F.J., Liao,F.,
            Yang-Yen,H.F. and Yen,J.J.
  TITLE     CBAP functions as a novel component in chemokine-induced
            ZAP70-mediated T-cell adhesion and migration
  JOURNAL   PLoS One 8 (4), e61761 (2013)
   PUBMED   23620790
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1578)
  AUTHORS   Shirpoor,A., Salami,S., Khadem-Ansari,M.H., Heshmatian,B. and
            Ilkhanizadeh,B.
  TITLE     Long-term ethanol consumption initiates atherosclerosis in rat
            aorta through inflammatory stress and endothelial dysfunction
  JOURNAL   Vascul Pharmacol 57 (2-4), 72-77 (2012)
   PUBMED   22521742
REFERENCE   5  (bases 1 to 1578)
  AUTHORS   Zhong,M., He,B., Yang,J., Bao,R., Zhang,Y., Zhou,D., Chen,Y.,
            Li,L., Han,C., Yang,Y., Sun,Y., Cao,Y., Li,Y., Shi,W., Jiang,S.,
            Zhang,X. and Yan,H.
  TITLE     L-selectin and P-selectin are novel biomarkers of cervicovaginal
            inflammation for preclinical mucosal safety assessment of
            anti-HIV-1 microbicide
  JOURNAL   Antimicrob Agents Chemother 56 (6), 3121-3132 (2012)
   PUBMED   22391529
REFERENCE   6  (bases 1 to 1578)
  AUTHORS   Billups,K.L., Palladino,M.A., Hinton,B.T. and Sherley,J.L.
  TITLE     Expression of E-selectin mRNA during ischemia/reperfusion injury
  JOURNAL   J Lab Clin Med 125 (5), 626-633 (1995)
   PUBMED   7537789
REFERENCE   7  (bases 1 to 1578)
  AUTHORS   Kajihara,J., Guoji,Y., Kato,K. and Suzuki,Y.
  TITLE     Sulfatide, a specific sugar ligand for L-selectin, blocks
            CCl4-induced liver inflammation in rats
  JOURNAL   Biosci Biotechnol Biochem 59 (1), 155-157 (1995)
   PUBMED   7534512
REFERENCE   8  (bases 1 to 1578)
  AUTHORS   Watanabe,T., Song,Y., Hirayama,Y., Tamatani,T., Kuida,K. and
            Miyasaka,M.
  TITLE     Sequence and expression of a rat cDNA for LECAM-1
  JOURNAL   Biochim Biophys Acta 1131 (3), 321-324 (1992)
   PUBMED   1378303
REFERENCE   9  (bases 1 to 1578)
  AUTHORS   Mulligan,M.S., Varani,J., Dame,M.K., Lane,C.L., Smith,C.W.,
            Anderson,D.C. and Ward,P.A.
  TITLE     Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in
            neutrophil-mediated lung injury in rats
  JOURNAL   J Clin Invest 88 (4), 1396-1406 (1991)
   PUBMED   1717513
REFERENCE   10 (bases 1 to 1578)
  AUTHORS   Bowen,B.R., Nguyen,T. and Lasky,L.A.
  TITLE     Characterization of a human homologue of the murine peripheral
            lymph node homing receptor
  JOURNAL   J Cell Biol 109 (1), 421-427 (1989)
   PUBMED   2663882
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Nov 27, 2020 this sequence version replaced NM_019177.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: S79523.1, SRR26643292.49811.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000013.1  78950401-78950508
            109-190             JAXUCZ010000013.1  78951325-78951406
            191-577             JAXUCZ010000013.1  78953457-78953843
            578-685             JAXUCZ010000013.1  78954337-78954444
            686-871             JAXUCZ010000013.1  78957190-78957375
            872-1057            JAXUCZ010000013.1  78958890-78959075
            1058-1186           JAXUCZ010000013.1  78960429-78960557
            1187-1205           JAXUCZ010000013.1  78964479-78964497
            1206-1578           JAXUCZ010000013.1  78967983-78968355
FEATURES             Location/Qualifiers
     source          1..1578
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q23"
     gene            1..1578
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /note="selectin L"
                     /db_xref="GeneID:29259"
                     /db_xref="RGD:3655"
     exon            1..108
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1224
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /note="selectin, lymphocyte; LAM-1; ly-22; LECAM1;
                     lymphocyte antigen 22; lymph node homing receptor;
                     leukocyte adhesion molecule 1; CD62 antigen-like family
                     member L; lymphocyte surface MEL-14 antigen;
                     leukocyte-endothelial cell adhesion molecule 1"
                     /codon_start=1
                     /product="L-selectin precursor"
                     /protein_id="NP_062050.3"
                     /db_xref="GeneID:29259"
                     /db_xref="RGD:3655"
                     /translation="MVFPWRCQSAQRGSWSFLKLWIWTLLCCDLLPHHGTHCWTYHYS
                     ERSMNWENARKFCKHNYTDLVAIQNKREIEYLEKTLPKNPTYYWIGIRKIGKTWTWVG
                     TNKTLTKEAENWGTGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTASC
                     QPESCNRHGECVETINNNTCICDPGYYGPQCQYVIQCEPLKAPELGTMNCIHPLGDFS
                     FQSQCAFNCSEGSELLGNAKTECGASGNWTYLEPICQVIQCMPLAAPDLGTMECSHPL
                     ANFSFTSACTFTCSEETDLIGERKTVCRSSGSWSSPSPICQKTKRSFSKIKEGDYNPL
                     FIPVAVMVTAFSGLAFIIWLARRLKKGKKSQERMDDPY"
     exon            109..190
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            191..577
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            578..685
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            686..871
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            872..1057
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1186
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1205
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1578
                     /gene="Sell"
                     /gene_synonym="A.11; L-selectin; LECAM-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acattcttcc tgagtgcagc acaccctcct tgtgcaagag cacagcgccc caggtgcaga
       61 agactgaggc ccgcagaagg acttacagaa gagacccagc aagccatggt gtttccatgg
      121 agatgtcaga gtgctcagcg gggctcctgg agcttcctga agctgtggat ctggacactg
      181 ctgtgttgtg atctcctgcc acaccatgga actcactgtt ggacttacca ttattctgaa
      241 agatccatga actgggaaaa tgctagaaag ttctgcaagc acaattacac agatttagtt
      301 gctatacaaa ataagagaga aattgagtat ttggaaaaga cattacccaa aaaccctacc
      361 tactactgga taggaatcag gaaaatcggg aaaacgtgga catgggtggg aaccaacaaa
      421 accctcacca aagaagcaga gaactggggt actggggagc ccaacaacaa gaagtctaag
      481 gaagactgcg tggagatcta tatcaagagg gaacgagact ctgggaagtg gaatgacgat
      541 gcctgccaca aacgaaaggc agctctctgc tacacagcct cctgccaacc agaatcttgc
      601 aaccgccatg gagaatgtgt ggaaactatc aacaataaca cctgcatctg tgacccaggg
      661 tattatgggc cccagtgtca gtatgtgatc caatgtgagc ctttgaaggc ccctgagctg
      721 ggtaccatga actgtattca ccccttggga gacttcagct tccagtcaca gtgtgctttc
      781 aactgttctg agggaagcga gctacttggg aatgcaaaaa cagagtgtgg agcatctgga
      841 aactggacat atctagagcc aatctgtcaa gtgattcagt gcatgcctct agcagcaccg
      901 gatctgggca ctatggaatg cagtcacccc ctcgccaact tcagttttac ttctgcttgt
      961 accttcacct gctcagaaga aactgactta attggggaga gaaaaactgt ctgcagatca
     1021 tctggctcct ggtctagtcc tagtccaata tgtcaaaaga caaagagaag tttctcaaag
     1081 atcaaggaag gcgactataa ccccctcttc attccagtag ctgtcatggt cactgcattc
     1141 tcagggctgg catttatcat ttggctggca aggcggctaa aaaaaggcaa gaaatcgcag
     1201 gaaaggatgg atgatcctta ctgattgatc ctttgtgaga ggaaagtcat aaggtactaa
     1261 caaccgccac caaaaaccat tggaagacaa cttcaacacc tcctgtgaag attttgcaca
     1321 cgggcatctc ccacgttaga gatgcagtgt ttgctcagtg taactgagag gatttcaaca
     1381 cgaccaacag ctcctcctaa tttcctctca ctcactcatc ctataaatct attccataac
     1441 ttgtgcttat acagatcggt attttatcat cttttctgtg aaagaacaaa taagacaatt
     1501 gagcaaaaga gttactgtag gatataaaga tacctgcttt tactcttccc caactctcgt
     1561 ttcctctttc agtgccaa
//
