LOCUS       NM_001014049            2238 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Rattus norvegicus SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase
            (Sel1l2), mRNA.
ACCESSION   NM_001014049 XM_230648
VERSION     NM_001014049.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2238)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2238)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083893.1.
            
            On Apr 20, 2005 this sequence version replaced XM_230648.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083893.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2238
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..2238
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /note="SEL1L2 adaptor subunit of SYVN1 ubiquitin ligase"
                     /db_xref="GeneID:311470"
                     /db_xref="RGD:1311278"
     exon            1..130
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..2139
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /note="protein sel-1 homolog 2; sel-1L2; suppressor of
                     lin-12-like protein 2; sel-1 suppressor of lin-12-like 2;
                     SEL1L2 ERAD E3 ligase adaptor subunit; SEL1L2 adaptor
                     subunit of ERAD E3 ligase; SEL1L2 adaptor subunit of ERAD
                     E3 ubiquitin ligase"
                     /codon_start=1
                     /product="protein sel-1 homolog 2 precursor"
                     /protein_id="NP_001014071.1"
                     /db_xref="GeneID:311470"
                     /db_xref="RGD:1311278"
                     /translation="MNPLALLVEILIIIEVTTKNSEAERYNRKQKEVNVTTQVSVSKV
                     KQFLSHLLEQGKANKIANKRENPLEKKKHQHKLKIKGIQNKNLLKRNQNYFKKPAKKS
                     ITDKGDELFKMGNKILQESKSQKQKTEAYTFFTRAADMGNLKAMEKMADALLFGSFGM
                     QNITAAIQLYESLAKEGSYKAQNALGFLSSYGIGMEYDQAKALIYYTFGSAGGSMMSQ
                     MILGYRYLSGINVLQNCEVALNHYKKVADYIADKLEKSEGIPVEKVRLTERPENLSSN
                     SEILDWDIYQYYKFLAERGDVQIQVSLGQLHLIGRKGLDQDYSKALYYFLKAAKAGSA
                     NAMAFIGKMYLEGNAAAPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPVNYG
                     EALKYFQKAAEKGWPNAQFHLGFMYYSGSGVWKDYKLAFKYFYLASQSGQPLAIYYLA
                     EMYATGTGVLRSCRTAVEPYKGVCELGHWAEKFLTAYFAYKDGDVDSSLIQYALLAEM
                     GYEVAQSNSAFILESKKAKILGKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYG
                     TKKDYETAATHYSIAADKHHSAQAMFNLAYMYEHGLGIAQDIHLARRLYDMAAQTSPD
                     AHIPVFFALMKLETMHFLQDILFFNFTTKWKWLKLDSTIGPYWDLLVIGLIVVVLIFL
                     LRNHHR"
     exon            131..186
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            187..355
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            356..458
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            459..621
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            622..675
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            676..735
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            736..817
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            818..972
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1029
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1098
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1176
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1239
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1327
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1476
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1642
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1717
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1890
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            1891..2019
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2215
                     /gene="Sel1l2"
                     /gene_synonym="RGD1311278"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgagaagag gaagcttgtg ggccagccac ctaattctgc ctgtgttaaa gtgaaaagga
       61 gctgcttagg agatgaatcc cttggctttg ttagtagaga tattgatcat tattgaggtc
      121 acaactaaaa acagtgaagc agaaagatat aacagaaaac aaaaagaagt gaatgtcacc
      181 acacaggtat cagtgagcaa agtcaagcag tttttatcgc atctactgga acaaggaaaa
      241 gcaaataaaa tagccaataa aagagaaaat cccttagaaa aaaagaagca tcaacataag
      301 ttaaaaataa aaggaattca aaataagaat ctcctgaaga gaaatcaaaa ctacttcaaa
      361 aagccagcca agaaaagtat cacagataaa ggagatgagt tatttaagat gggcaacaag
      421 attctccagg agtctaaaag tcaaaaacaa aaaacagaag cctacacatt cttcaccaga
      481 gcagccgaca tgggaaattt gaaagctatg gaaaaaatgg ctgacgcttt gctatttgga
      541 agtttcggca tgcaaaacat aacagcagct atccagttat acgagtcctt ggctaaagaa
      601 ggatcataca aagcccaaaa tgcattggga tttttatctt cttatggaat aggaatggaa
      661 tatgaccaag ccaaggcact gatatattat acctttggaa gtgctggagg gagcatgatg
      721 tcccagatga ttctggggta cagatacttg tcaggaatta atgttctgca aaattgtgaa
      781 gttgctctaa atcattacaa gaaagtggca gattatattg ctgacaaatt ggaaaaaagt
      841 gaaggtattc ccgtggaaaa agtgaggcta accgagagac ctgagaatct gagttccaac
      901 agtgagattt tggattggga catataccaa tactataagt ttttggcaga aagaggagat
      961 gttcagatac aagtatctct tggacaattg catctaattg ggagaaaagg tctagatcaa
     1021 gattacagta aggcgttata ctactttcta aaggcagcaa aagctgggag tgcaaatgcc
     1081 atggcattta taggaaagat gtatttagag gggaacgctg ctgcaccaca aaataatgcc
     1141 actgccttca aatacttctc catggcggcc agcaagggca atgcaattgg tcttcatgga
     1201 ctcggtctcc tttacttcca tggaaaaggt gttcctgtga attatggcga agcacttaaa
     1261 tacttccaga aagctgcaga gaagggatgg ccaaacgcac agttccacct aggcttcatg
     1321 tactactctg gctctggagt atggaaggat tataagcttg ccttcaaata tttttacttg
     1381 gcatctcaga gtgggcagcc tctcgccatt tattatctag ccgagatgta cgcaactggc
     1441 accggagtgc tgagatcctg cagaacggcc gtggagcctt ataaaggagt ctgtgaacta
     1501 ggccactggg ctgagaaatt cctgacagcc tactttgcct ataaggatgg ggacgtagat
     1561 tcttctctaa ttcagtacgc gttgcttgcc gaaatgggat atgaagtagc tcaaagcaat
     1621 tcagcattca ttttggaatc caaaaaagct aaaattctgg ggaaagagaa gatgtatcca
     1681 atggcacttc tgctatggaa ccgagctgcc attcaaggga atgcttttgc tagagtgaaa
     1741 attggagatt accattacta tggctacggg actaagaagg actatgaaac agcagccaca
     1801 cactacagca tcgcagcaga caagcatcac agtgcgcaag ccatgttcaa cctggcatat
     1861 atgtatgagc acggcttggg gattgcacag gacattcact tggccagaag attatacgac
     1921 atggccgctc agacaagccc agatgctcac atacccgtgt tctttgccct tatgaaactg
     1981 gaaactatgc attttctcca agatatcctg ttttttaatt ttaccacgaa atggaaatgg
     2041 ctgaaactgg acagcaccat tggaccatac tgggacttat tagtgattgg cctaattgtt
     2101 gttgtgctga tcttcctgct tagaaaccac cataggtagg ctctggacca tcaggaaacc
     2161 tactcgtagc ttcatgctga gctatcctaa caaataaaga gtttcctcat ccaaaaaaaa
     2221 aaaaaaaaaa aaaaaaaa
//
