LOCUS       NM_001394994            3521 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus SEH1-like nucleoporin (Seh1l), mRNA.
ACCESSION   NM_001394994
VERSION     NM_001394994.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3521)
  AUTHORS   Wolfson,R.L., Chantranupong,L., Wyant,G.A., Gu,X., Orozco,J.M.,
            Shen,K., Condon,K.J., Petri,S., Kedir,J., Scaria,S.M.,
            Abu-Remaileh,M., Frankel,W.N. and Sabatini,D.M.
  TITLE     KICSTOR recruits GATOR1 to the lysosome and is necessary for
            nutrients to regulate mTORC1
  JOURNAL   Nature 543 (7645), 438-442 (2017)
   PUBMED   28199306
REFERENCE   2  (bases 1 to 3521)
  AUTHORS   Parmigiani,A., Nourbakhsh,A., Ding,B., Wang,W., Kim,Y.C.,
            Akopiants,K., Guan,K.L., Karin,M. and Budanov,A.V.
  TITLE     Sestrins inhibit mTORC1 kinase activation through the GATOR complex
  JOURNAL   Cell Rep 9 (4), 1281-1291 (2014)
   PUBMED   25457612
REFERENCE   3  (bases 1 to 3521)
  AUTHORS   Bonnet,A. and Palancade,B.
  TITLE     Regulation of mRNA trafficking by nuclear pore complexes
  JOURNAL   Genes (Basel) 5 (3), 767-791 (2014)
   PUBMED   25184662
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3521)
  AUTHORS   Bar-Peled,L., Chantranupong,L., Cherniack,A.D., Chen,W.W.,
            Ottina,K.A., Grabiner,B.C., Spear,E.D., Carter,S.L., Meyerson,M.
            and Sabatini,D.M.
  TITLE     A Tumor suppressor complex with GAP activity for the Rag GTPases
            that signal amino acid sufficiency to mTORC1
  JOURNAL   Science 340 (6136), 1100-1106 (2013)
   PUBMED   23723238
REFERENCE   5  (bases 1 to 3521)
  AUTHORS   Ahn,S.H., Deshmukh,H., Johnson,N., Cowell,L.G., Rude,T.H.,
            Scott,W.K., Nelson,C.L., Zaas,A.K., Marchuk,D.A., Keum,S.,
            Lamlertthon,S., Sharma-Kuinkel,B.K., Sempowski,G.D. and Fowler,V.G.
            Jr.
  TITLE     Two genes on A/J chromosome 18 are associated with susceptibility
            to Staphylococcus aureus infection by combined microarray and QTL
            analyses
  JOURNAL   PLoS Pathog 6 (9), e1001088 (2010)
   PUBMED   20824097
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3521)
  AUTHORS   Zuccolo,M., Alves,A., Galy,V., Bolhy,S., Formstecher,E., Racine,V.,
            Sibarita,J.B., Fukagawa,T., Shiekhattar,R., Yen,T. and Doye,V.
  TITLE     The human Nup107-160 nuclear pore subcomplex contributes to proper
            kinetochore functions
  JOURNAL   EMBO J 26 (7), 1853-1864 (2007)
   PUBMED   17363900
REFERENCE   7  (bases 1 to 3521)
  AUTHORS   Glavy,J.S., Krutchinsky,A.N., Cristea,I.M., Berke,I.C., Boehmer,T.,
            Blobel,G. and Chait,B.T.
  TITLE     Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160
            subcomplex
  JOURNAL   Proc Natl Acad Sci U S A 104 (10), 3811-3816 (2007)
   PUBMED   17360435
REFERENCE   8  (bases 1 to 3521)
  AUTHORS   Loiodice,I., Alves,A., Rabut,G., Van Overbeek,M., Ellenberg,J.,
            Sibarita,J.B. and Doye,V.
  TITLE     The entire Nup107-160 complex, including three new members, is
            targeted as one entity to kinetochores in mitosis
  JOURNAL   Mol Biol Cell 15 (7), 3333-3344 (2004)
   PUBMED   15146057
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR23984936.252759.1,
                                           SRR26360190.1746549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-241               JAXUCZ010000018.1  63616875-63617115
            242-292             JAXUCZ010000018.1  63621318-63621368
            293-439             JAXUCZ010000018.1  63624767-63624913
            440-651             JAXUCZ010000018.1  63626014-63626225
            652-750             JAXUCZ010000018.1  63628455-63628553
            751-891             JAXUCZ010000018.1  63632848-63632988
            892-1049            JAXUCZ010000018.1  63633520-63633677
            1050-1200           JAXUCZ010000018.1  63636252-63636402
            1201-3521           JAXUCZ010000018.1  63637532-63639852
FEATURES             Location/Qualifiers
     source          1..3521
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..3521
                     /gene="Seh1l"
                     /note="SEH1-like nucleoporin"
                     /db_xref="GeneID:100911798"
                     /db_xref="RGD:6490353"
     exon            1..241
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..1213
                     /gene="Seh1l"
                     /note="nucleoporin SEH1-like"
                     /codon_start=1
                     /product="nucleoporin SEH1"
                     /protein_id="NP_001381923.1"
                     /db_xref="GeneID:100911798"
                     /db_xref="RGD:6490353"
                     /translation="MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSES
                     GDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSH
                     WVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRVYEAPDVMNLSQWSLQHEIS
                     CKLCCSCISWNPSSSRAHPPMIAVGSDDSSPNSMAKVQIFEYNENTRKYAKAETLMTV
                     TDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGGPTKFEIHIVAQFDN
                     HNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKCTGILKGNGSPVNGSSQLGN
                     STPSLSSNIPNLQNSLNGTSAGRKHS"
     exon            242..292
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            293..439
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            440..651
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            652..750
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            751..891
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1049
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1200
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..3521
                     /gene="Seh1l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcgtggc gcgccggagc gacgcgagca ggcgagggcc gacgtaccgt acgtgcctct
       61 gccgcggtcc gggggctgcg ggccgcaccg ccgccctctc ggaggcgggc ccgggcagac
      121 ggcggcggcc atgtttgtgg cgcgcagcat cgcggcggac cacaaggacc tcatccacga
      181 tgtgtctttc gacttccacg ggcgccggat ggccacctgt tccagcgacc agagcgtcaa
      241 ggtgtgggat aagagcgaga gcggagattg gcactgcaca gctagttgga agacacatag
      301 tggatctgta tggcgtgtga catgggctca tcctgagttt ggacaagttt tggcttcctg
      361 ttcttttgac cgaacagcag ccgtatggga agaaatagta ggagagtcaa acgataaact
      421 tcgaggacag agtcactggg tgaaaaggac aactctagtg gacagcagaa catctgttac
      481 agatgtgaaa tttgctccca agcacatggg tctgatgtta gcaacctgct ctgcagatgg
      541 catcgtgaga gtctacgagg ccccagatgt gatgaacctc agccagtggt ccctgcagca
      601 cgagatctcg tgtaagctgt gctgcagctg catttcttgg aacccttcca gctctcgtgc
      661 tcaccccccc atgatcgctg tgggaagtga tgacagcagt ccaaattcaa tggccaaggt
      721 tcagatcttt gagtacaatg aaaacaccag gaaatatgca aaagctgaga ctcttatgac
      781 agtcacggat cctgtccatg acattgcgtt tgctccaaat ttgggacgat ctttccacat
      841 cctggcaata gcaaccaaag atgtaagaat tttcacatta aaacctgtga ggaaagaact
      901 tacttcttct ggtggtccaa caaaatttga aatccatatt gtggctcagt ttgataatca
      961 taattctcag gtctggaggg tgagttggaa cataacagga acagtattgg cgtcttcagg
     1021 agatgacggc tgtgttaggt tgtggaaagc taattacatg gacaattgga agtgcactgg
     1081 tattttgaaa ggtaacggga gcccagtaaa tgggagttct cagctgggaa actcaactcc
     1141 ttcactgagc tcaaatattc caaatcttca aaattcatta aatggaacat ctgctggcag
     1201 aaagcacagc tgagtgcacg ctagctggag tgactgtgct gctgtgctgc ttgttgcatg
     1261 cacacaggaa tggaaaccaa cttctttccc tccccagcgc cgtgtgatct ccacgatgca
     1321 ccagcagcct gttcactact acacacaggc ccaaaggcct ttaaatgaca gtgtatataa
     1381 cttctgtact agtcagactc ctgacactat aaatggaaag gctttttgtt gacatatcat
     1441 caccaaaaca attttttgga atgttctgga gactaacttg ggtttaaaaa ctgaaaagat
     1501 tgctattatc ctcataagca gttgggagga gggcaaatat aattttattc catttggaaa
     1561 atataggaat atgtctttta ttttctaaaa caataagcta aaatgatgag tttttataat
     1621 tttaatttga aaaatcaaat aaatattttc ataaagattg ttttgagtgg taatgtgttt
     1681 accttttgta gaattgctct gtaggtgaca ttatccacac aactacttta caggtgacat
     1741 tatccacaca actacatctc ttgtaattaa aatactagta caggaacaga tcagtaacgt
     1801 ggcaccagtt gagctcaaat agtttgtagc caagcagcac attagcaatt gctggtttta
     1861 ttggtagtaa aatggtgaca gcacttctaa gttttcatct catattcagg agatggctgt
     1921 ttctaatcta tgcatgaatg tttatggtgt gatcctatac aacttggttt cctttaagac
     1981 aatttggaaa catgagttga catttttcag aaaatgtgcg tgcagttaaa attccgtgtc
     2041 tcaggatttt taatgtgtta tttcaaagag tccctgtatt ctgaaacttt tgactttgat
     2101 gatagttata caccttttca cttactaaac tgcatacata ttacgggtaa gttatgagat
     2161 ggtagaataa caggctataa ttctttgagc ctttttatgc accaaaattc tgtaggtatt
     2221 ctaagttttt tgcaggaaac gaagcctgtg caatgattgt atttctcaag catgtggagt
     2281 gcagtagcca ggtctcccgg tagtgagttg gagctggttc tcggtatcat gtatgcacta
     2341 acgtgtgcct gctgctgtaa cacatgcagc tctgctggaa aggaagagca gatgtgtgaa
     2401 ttaaggaatc aaatgagatt agacacgctt tcagtttata aaatgaatgt ctctgtaaca
     2461 tacgtcctga tgattttggg ggcattttaa ctttaacaga ttgtattttt ttttaaaatt
     2521 tttatacttc ttaagcagcc ttgattcaag tgagagtctt gatttgtact gttctatcgg
     2581 ttgtggcatg aatatacagc tttttttcct tccttccagc atgttttctc ttctttggtt
     2641 ctctttgtat ttactgcttt tctctttttc ttctgtttcc ctccctcctt tccccctgtt
     2701 gtttttgttt tggtgttttg ttcctgtctt cattatttca ggtatttctt tccccctctg
     2761 gattccccac gggctggatc aagatggtcc agctgtgccc agctccttcc tcctcctgct
     2821 cctctgctag agcactcttg tgatgcagac actgccaacc tccactatcc tcaccctcgc
     2881 agaggatgcc tctctcggcc tcttaatccc ttacctgaga atgaaggggt gtaaaatcct
     2941 gatttaaagg ccttacccag atgcttgtaa atgcttttat tccgggctgc ttttggtttc
     3001 ttcattttct tttagaagat ccttcctagt taggccatgt cttgcatgta tcacaactcg
     3061 agtgtttgaa accaaacctg tttgtacttc tgcaccagga aaccttggct tcactagttg
     3121 gttaccttgg acgagatgag cttcagaaaa agcaatatta actgtgaacg attcccagta
     3181 tctggttcaa agtgcctgtc ttgtacattc attctgtgtg gacttgttat catagagttc
     3241 agttttgtct gttgatggta gcttcagagg aaagcatatc attgtgaact tcactctgta
     3301 attcagacat taagaaatgt ttggaatttt ataggctgat gttacaaatg actgtaaaat
     3361 aaatcattcc tgtgtataaa gcagcaaatc ataaggatat ttttgtcttt tttttttttt
     3421 tttaaaggaa aatgcctttt actacttgga attactactt aaaaattttg taactgttct
     3481 ccaagtaggt tatttaataa aagtatttta aaagatgtga a
//
