LOCUS       NM_001309453            3923 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus SEC24 homolog D, COPII coat complex component
            (Sec24d), mRNA.
ACCESSION   NM_001309453 XM_003749389 XM_003753659
VERSION     NM_001309453.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Tomoishi,S., Fukushima,S., Shinohara,K., Katada,T. and Saito,K.
  TITLE     CREB3L2-mediated expression of Sec23A/Sec24D is involved in hepatic
            stellate cell activation through ER-Golgi transport
  JOURNAL   Sci Rep 7 (1), 7992 (2017)
   PUBMED   28801610
  REMARK    GeneRIF: Sec24D expression is upregulated via CREB3L2 during
            hepatic stellate cells activation.  Sec24D knockdown abrogated the
            activation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  AUTHORS   Adams,E.J., Chen,X.W., O'Shea,K.S. and Ginsburg,D.
  TITLE     Mammalian COPII coat component SEC24C is required for embryonic
            development in mice
  JOURNAL   J Biol Chem 289 (30), 20858-20870 (2014)
   PUBMED   24876386
REFERENCE   3  (bases 1 to 3923)
  AUTHORS   Baines,A.C., Adams,E.J., Zhang,B. and Ginsburg,D.
  TITLE     Disruption of the Sec24d gene results in early embryonic lethality
            in the mouse
  JOURNAL   PLoS One 8 (4), e61114 (2013)
   PUBMED   23596517
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3923)
  AUTHORS   Bonnon,C., Wendeler,M.W., Paccaud,J.P. and Hauri,H.P.
  TITLE     Selective export of human GPI-anchored proteins from the
            endoplasmic reticulum
  JOURNAL   J Cell Sci 123 (Pt 10), 1705-1715 (2010)
   PUBMED   20427317
REFERENCE   5  (bases 1 to 3923)
  AUTHORS   Mancias,J.D. and Goldberg,J.
  TITLE     Structural basis of cargo membrane protein discrimination by the
            human COPII coat machinery
  JOURNAL   EMBO J 27 (21), 2918-2928 (2008)
   PUBMED   18843296
REFERENCE   6  (bases 1 to 3923)
  AUTHORS   Mancias,J.D. and Goldberg,J.
  TITLE     The transport signal on Sec22 for packaging into COPII-coated
            vesicles is a conformational epitope
  JOURNAL   Mol Cell 26 (3), 403-414 (2007)
   PUBMED   17499046
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1 and BC168946.1.
            
            On or before Jun 3, 2015 this sequence version replaced
            XM_003749389.3, XM_003753659.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR21887623.808496.1,
                                           SRR26643299.12080.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                JAXUCZ010000002.1  214103200-214103263
            65-224              JAXUCZ010000002.1  214105354-214105513
            225-354             JAXUCZ010000002.1  214112886-214113015
            355-503             JAXUCZ010000002.1  214125017-214125165
            504-779             JAXUCZ010000002.1  214128921-214129196
            780-913             JAXUCZ010000002.1  214129469-214129602
            914-1025            JAXUCZ010000002.1  214134768-214134879
            1026-1083           JAXUCZ010000002.1  214138284-214138341
            1084-3923           BC168946.1         1-2840
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     gene            1..3923
                     /gene="Sec24d"
                     /note="SEC24 homolog D, COPII coat complex component"
                     /db_xref="GeneID:310843"
                     /db_xref="RGD:1311720"
     exon            1..64
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            65..224
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..3211
                     /gene="Sec24d"
                     /note="SEC24 related gene family, member D; SEC24 family
                     member D"
                     /codon_start=1
                     /product="protein transport protein Sec24D"
                     /protein_id="NP_001296382.1"
                     /db_xref="GeneID:310843"
                     /db_xref="RGD:1311720"
                     /translation="MSQQGYVATPPYSQSQPGMGISPPHYGHYGDPSHVSSPPGMMKP
                     PGPTGATAPSGLLPPGPLPPGPPQFGPNGAHAAGHPPQRFPGHPPVNNAAPPYASGQP
                     LPQSSYPGPGSTSSVTQLGSQFGSMQINNYGVGVTPQGQGPPGPQSAGAFQGPPQPTQ
                     PSILQPGPQVPPPPPTAMNGPGASPMSAPAHRQDGLPAPTPLNAQYQPPPPPGQTLGA
                     GYHPQQAANYGPQMGGAQLSYPGGFPGGPAQMAGPAPQLQRKLDPDSIPSPIQVIEND
                     RATRGGQVYTTNTRGQVPPLVTTECMIQDQGHSSPRYIRCTTYCFPCTSDMAKQAQIP
                     LAAVIKPFADIPSNETPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCSC
                     VNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMIDV
                     SYSNIKNGLVKLICEELKTVLKRLPKEEHEEKSAIRVGFITYNKVLHFFNVKSNLAQP
                     QMMVVTDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNENETVFAPVIQAG
                     MEALKAAECPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLA
                     KDCVANSCSVTLFLFPSQFVDVASLGLVPLLTGGSLYKYNVFQVHVDSQRFLNDLRND
                     IEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLS
                     EDVGALIQCALLYTTIGGQRRLRIHNVALNCSTQLADLYKSCETDALINFFAKSAFKA
                     VLNQPLKTIREILVNQTAHMLACYRKHCASPSAASQLILPDSMKVLPVYMNSLLKNCV
                     LLSRPEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHTLDVKSAALPPAVRCSESR
                     LSEEGIFLLADGLNMFLWFGVGSPAELIQGIFNVPSFAHINTDMTSLPEVGSPHSQQL
                     RMIMNNIQQKKPYSMKLIIVKQREQREMVFRQFLVEDKGLYGGSSYVDFLCCVHKEIC
                     QLLN"
     exon            225..354
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            355..503
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            504..779
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            780..913
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1025
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1153
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1292
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1408
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1533
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1725
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1819
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1936
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2107
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2204
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2350
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2351..2489
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2608
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2609..2788
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2789..2980
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..3070
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
     exon            3071..3889
                     /gene="Sec24d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcgcagcc cagagcgact cggcggcggc ggcggtggcg cggggcgcgg agcgtgcaga
       61 gcaggattct tctgcagtag ctctcctttg gaatgatatt ttcataatga gccaacaagg
      121 ttacgtggcg acacccccct attctcagtc ccagcctgga atgggcattt ctccccctca
      181 ctacgggcac tatggggacc cgtcccatgt gtcctctcca ccaggcatga tgaagcctcc
      241 ggggcctaca ggagccactg ctccttcagg gctgctgccc ccaggtcctt tacctcctgg
      301 acccccacag tttggtccca atggagccca tgccgcaggc catcctcctc aaagatttcc
      361 gggacaccca cccgtcaata atgcagcacc cccttatgca tcaggccagc ccctgccaca
      421 gtcatcttac ccaggtcctg ggtccacctc ctctgtcacc cagctgggca gtcagttcgg
      481 ctccatgcag atcaacaact atggtgtggg cgtgactccc cagggccagg gtccgcctgg
      541 cccccagtca gcaggcgcct ttcaggggcc tccacagcct acacagccat ctattctgca
      601 gccaggacct caggttccac caccaccacc caccgccatg aacggccctg gtgcctctcc
      661 aatgtctgca ccagctcaca ggcaagatgg acttcctgcg cctactcctc tgaatgccca
      721 gtatcaacct ccacctccac caggccagac cctgggtgct ggttaccatc cacagcaagc
      781 agccaactat ggaccacaga tgggaggtgc acagctgtcc tacccaggag gttttcctgg
      841 aggtccggca cagatggctg ggccagcacc tcagctccag aggaagcttg atccagactc
      901 catccccagc cccattcaag tgatcgagaa tgacagggcc accagaggcg gacaggtcta
      961 taccaccaac accaggggcc aggtgcctcc actggtcacc accgagtgta tgattcaaga
     1021 tcaaggccac tcgagccccc gctacattcg ctgtaccaca tactgcttcc catgcacgtc
     1081 agacatggcc aagcaagccc agatcccact agctgccgtc atcaaaccct ttgctgacat
     1141 tccatcaaac gagaccccct tgtacttggt gaaccatgga gagagcggac cagtgagatg
     1201 caacaggtgc aaagcctaca tgtgcccgtt catgcagttc atcgaaggcg gacggcgcta
     1261 tcagtgcgga ttttgcagct gcgtgaacga tgtcccaccg ttctatttcc aacatctgga
     1321 ccacattggg agaagactgg accactatga gaagccagag ctgtctttag gatcctatga
     1381 atatgttgct actttggatt actgcagaaa gaataaacca cccaacccac cagcctttat
     1441 cttcatgatc gatgtctcgt acagtaacat aaagaacggg ctcgtcaagc tcatctgtga
     1501 ggaactgaag accgtgctga agaggctacc caaggaggag catgaggaga aatctgcaat
     1561 tcgagttggt ttcatcacat acaacaaagt tctccacttc tttaacgtga agagtaatct
     1621 ggcccaacct cagatgatgg tggtgacgga tgttggagag gtctttgttc ctttgttgga
     1681 tgggttcctt gtcaactatg aagaatccca gtctgtgatc cacaatttat tggaccagat
     1741 tcctgagatg tttgccgact ccaatgaaaa cgagacagtc tttgctcctg tcatccaggc
     1801 tggcatggag gccctgaagg cagcagagtg ccctgggaag ctcttcatct tccattcgtc
     1861 cctgcctact gccgaagcac cgggaaagct caagaacaga gacgacaaaa agctggttaa
     1921 cacagacaag gagaagatac ttttccagcc ccaaacagct gtctacgaat ctctggccaa
     1981 ggactgtgta gccaacagct gctcggtgac tctgttcctc tttcccagtc agtttgtgga
     2041 tgtggcttcc ttgggtctgg ttcctctgct cacgggagga tccctttaca aatacaatgt
     2101 ttttcaggta cacgtggata gtcaaaggtt tttgaacgac ctccggaatg atattgagaa
     2161 gaaaataggc ttcgatgcta tcatgagggt tcggaccagc acaggtttca gggccaccga
     2221 tttcttcggt gggatattca tgaacaacac cacagatgtg gaaatggcag ccatcgactg
     2281 tgataaggcg gtgaccgtgg agttcaagca cgatgacaag ctcagtgaag atgtcggggc
     2341 tctgatccag tgtgccctgc tctacacgac catcggtggt cagcgaagac tccggattca
     2401 caatgtcgcc ttaaactgca gcacccagct agcagatctg tacaagagct gtgaaacaga
     2461 tgccctgatc aacttctttg ccaagtcagc ttttaaagcc gttttgaacc agcctttgaa
     2521 gaccatccgg gaaattctag ttaatcagac tgcccatatg ttggcgtgtt accggaagca
     2581 ctgtgcgagc ccttctgcag caagccagct tatactgcca gattccatga aagttctgcc
     2641 cgtgtacatg aacagtctgt tgaaaaactg tgtgctgctc agcagacccg agatctcccc
     2701 tgacgagcgg gcgtaccaac ggcagctggt gatgaccatg ggcgtggctg actcccagct
     2761 cttcttctat ccactgctcc tgccaataca cacgttggat gtgaagagcg cagcactgcc
     2821 gccggctgtc cgctgctccg agtcccgact ctccgaagaa ggaatattcc tgctggctga
     2881 tggtctgaac atgttcttgt ggttcggagt ggggagccca gcggagctga ttcagggaat
     2941 attcaatgtg ccatcgtttg cacatatcaa cacagatatg acatcgctgc ctgaggtggg
     3001 aagtccgcac tctcaacaac tcaggatgat tatgaataat atccagcaga agaagccata
     3061 ctcaatgaag ctcatcatag tgaagcagcg agagcagcgg gagatggttt tccgacagtt
     3121 cctggtggaa gacaaagggc tctacggagg atcatcttat gtggatttcc tctgctgtgt
     3181 gcacaaggag atctgtcagc tgcttaactg agtactccgc tctcccactg aggctgcatc
     3241 cctgaggaga cagtctccga cttggtgcct aattttctga tgatagtagg ctagttttaa
     3301 tttctcgatt actttcagga tagcttgcct ggacagcacc cagaccgtca gctttggtgc
     3361 tcagtggtag cccgtggagg ggtagtgtac tgtaaaggga acactatttg ctgtccaact
     3421 tctaatttct aaagctgaca caatttgcat ttcataaata catagtttac agaaccattt
     3481 gcagcctcaa ttttctttgt gcttgatata taaattattt ttcaaactgt atagattcat
     3541 ggtaaaatta tcttggttcc tctctctttt acaatgagag gaaaagattt catttttatc
     3601 ttacacctaa tgtttttaaa accccgtgac tacattaaac agattttttt tttcaactta
     3661 agatctgcaa cagcagactt ttaaaaaagc ctgaaatctg tctggtagaa caatttgtgt
     3721 tctccttttt tcataattat atattgtctg tttaaaatat tttccagttg ttttgtctat
     3781 aaaatggtat ctatattctt aatggttctt tgtacaattt tgatggtttc tacctgtata
     3841 taatggatct taaccaatat caataaatta cttcatgtac tctggcttaa aaaaaaaaaa
     3901 aaaaaaaaaa aaaaaaaaaa aaa
//
