LOCUS       NM_001109456            4457 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus SEC24 homolog C, COPII coat complex component
            (Sec24c), mRNA.
ACCESSION   NM_001109456 XM_001061137 XM_001061263 XM_001061319 XM_001061382
            XM_001061441 XM_001061501
VERSION     NM_001109456.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4457)
  AUTHORS   Adams,E.J., Chen,X.W., O'Shea,K.S. and Ginsburg,D.
  TITLE     Mammalian COPII coat component SEC24C is required for embryonic
            development in mice
  JOURNAL   J Biol Chem 289 (30), 20858-20870 (2014)
   PUBMED   24876386
REFERENCE   2  (bases 1 to 4457)
  AUTHORS   Montgomery TR, Steinkellner T, Sucic S, Koban F, Schuchner S, Ogris
            E, Sitte HH and Freissmuth M.
  TITLE     Axonal targeting of the serotonin transporter in cultured rat
            dorsal raphe neurons is specified by SEC24C-dependent export from
            the endoplasmic reticulum
  JOURNAL   J Neurosci 34 (18), 6344-6351 (2014)
   PUBMED   24790205
  REMARK    GeneRIF: Axonal delivery of serotonin transporter is contingent on
            recruitment of SEC24C in the endoplasmic reticulum.
REFERENCE   3  (bases 1 to 4457)
  AUTHORS   Bonnon C, Wendeler MW, Paccaud JP and Hauri HP.
  TITLE     Selective export of human GPI-anchored proteins from the
            endoplasmic reticulum
  JOURNAL   J Cell Sci 123 (Pt 10), 1705-1715 (2010)
   PUBMED   20427317
REFERENCE   4  (bases 1 to 4457)
  AUTHORS   Mancias JD and Goldberg J.
  TITLE     Structural basis of cargo membrane protein discrimination by the
            human COPII coat machinery
  JOURNAL   EMBO J 27 (21), 2918-2928 (2008)
   PUBMED   18843296
REFERENCE   5  (bases 1 to 4457)
  AUTHORS   Mancias JD and Goldberg J.
  TITLE     The transport signal on Sec22 for packaging into COPII-coated
            vesicles is a conformational epitope
  JOURNAL   Mol Cell 26 (3), 403-414 (2007)
   PUBMED   17499046
REFERENCE   6  (bases 1 to 4457)
  AUTHORS   Tang BL, Kausalya J, Low DY, Lock ML and Hong W.
  TITLE     A family of mammalian proteins homologous to yeast Sec24p
  JOURNAL   Biochem Biophys Res Commun 258 (3), 679-684 (1999)
   PUBMED   10329445
REFERENCE   7  (bases 1 to 4457)
  AUTHORS   Pagano A, Letourneur F, Garcia-Estefania D, Carpentier JL, Orci L
            and Paccaud JP.
  TITLE     Sec24 proteins and sorting at the endoplasmic reticulum
  JOURNAL   J Biol Chem 274 (12), 7833-7840 (1999)
   PUBMED   10075675
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474061.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061382.1, XM_001061319.1, XM_001061441.1, XM_001061263.1,
            XM_001061501.1, XM_001061137.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC168663.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4457
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     gene            1..4457
                     /gene="Sec24c"
                     /note="SEC24 homolog C, COPII coat complex component"
                     /db_xref="GeneID:685144"
                     /db_xref="RGD:1597739"
     exon            1..52
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            53..252
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..3368
                     /gene="Sec24c"
                     /note="SEC24 related gene family, member C; SEC24 family,
                     member C"
                     /codon_start=1
                     /product="protein transport protein Sec24C"
                     /protein_id="NP_001102926.1"
                     /db_xref="GeneID:685144"
                     /db_xref="RGD:1597739"
                     /translation="MNVNQSAPPVPPFGQNQPIYPGYHQSNYGGQPGPAAPATPYGAY
                     NGPVPGYQQAPPQGVPRAPPCSGAPPASAAQVPCGQTTYGQFGQGDIQNGPSSTAQMP
                     RVPGSQQFGPPLAPVVSQPAVLQPYGPPPTSTQVTAQLAAMQISGAVAQAPPPSGLGY
                     GPPTSLASASGNFPNSGPYSTYPQSQAPPLSQAQGHPGVQPPLRSAPPLASSFTSPAS
                     GGPRMPSMPGPLPPGQGFGSLPVSQANRVSSPPAHALPPGTQMTGPPAPPPPMHSPQQ
                     PGYQLQQNGSFGPARGPQPNYESPYPGAPTFGTQPGPPQPLPPKRLDPDAIPSPIQVI
                     EDDRNNRGSEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQA
                     QVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKAYMCPLMTFIEGGRRFQCSF
                     CSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFM
                     IDVSYNAIRTGLVRLLCEELKSLLDYLPREGGAEESAIRVGFVTYNKVLHFYNVKSSL
                     AQPQMMVVSDVADMFVPLLDGFLVNVSESRAVITSLLDQIPEMFADTRETETVFAPVI
                     QAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGTYQ
                     TLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYACFQVENDQERFLSDL
                     RRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDD
                     RLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFA
                     YRAVVSSPVKTVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLK
                     SDVLQPGAEVTTDDRAYVRQLVSSMDVAETNVFFYPRLLPLTKSPLDSTTEPPAVRAS
                     EERLSSGDIYLLENGLNLFVWVGASVQQGVVQSLFNVSSFSQITSGLSVLPVLDNPLS
                     KKVRGLIDTLRAQRTRYMKLIVVKQEDKLEMLFKHFLVEDKSLSGGASYVDFLCHMHK
                     EIRQLLS"
     exon            253..388
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            389..561
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            562..933
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1070
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1182
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1310
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1449
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1565
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1690
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1882
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1976
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2093
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2264
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2361
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2507
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2508..2646
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2765
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2766..2945
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            2946..3137
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            3138..3227
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
     exon            3228..4457
                     /gene="Sec24c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcttgggag ccttgacgtt aggaacgaag tcgaacctgg atctggagcc gggtgagatc
       61 aaatcgggga tgctctcata atgaatgtca accagtcagc tccacctgtt ccaccatttg
      121 ggcagaacca gcccatctac ccagggtatc atcagtctaa ttatggtggg caaccaggac
      181 ctgcagcccc tgctactccc tatggagcct acaatggccc agtgccaggc tatcagcagg
      241 cacctcctca aggtgtgccg agagccccac cttgctcagg ggcacctcca gcttctgcag
      301 cgcaggtccc ttgtggtcag actacatatg gccaatttgg ccaaggagac atacagaatg
      361 ggccaagttc cacagcccag atgccaaggg tccccggttc gcagcagttt gggcccccgt
      421 tggcccctgt ggtcagccag cctgccgtgc ttcagcccta cggccctccc cccacaagta
      481 cacaggtgac cgcgcagctg gccgcgatgc agatcagtgg tgctgtggcc caagccccgc
      541 ccccttctgg gttgggctac ggtccaccaa catcattggc ctcagcctca ggaaatttcc
      601 ctaattctgg accgtacagc acctatcctc agagccaggc tcctcccctt agccaggctc
      661 aaggtcatcc tggagtccag cctcccctgc gatctgctcc accactggct tccagcttca
      721 catccccagc ttcaggtggt cctcggatgc cttccatgcc tggtccactc ccgcctggac
      781 agggctttgg gagtctccca gtgagccagg ctaatcgcgt gtcctcgcct cctgcccatg
      841 ctctgcctcc aggcacccag atgactgggc ccccagcccc accaccacct atgcactccc
      901 cgcagcagcc gggttatcag ctgcagcaaa acggttcctt tggaccagcc cgaggccccc
      961 aacctaatta tgagagccca taccctggag cacctacctt tggcactcag cctgggcctc
     1021 ctcagccatt gcctcctaag cgcctggacc ctgatgccat ccccagccct attcaggtta
     1081 ttgaagacga tagaaacaac cggggttcag agccatttgt tactggtgta cggggacagg
     1141 tgccaccttt agtcaccacc aatttcctgg tgaaagacca agggaatgca agtccccgtt
     1201 acattcgatg cacctcctac aatatccctt gtacatctga catggctaag caggctcagg
     1261 tgcctctggc agctgtcatc aagccactgg caaggctgcc cccagaggag gcttcaccat
     1321 atgttgtgga ccatggcgaa tccggccccc tgcgctgtaa tcgctgcaaa gcatacatgt
     1381 gccctctcat gacattcatc gagggaggga ggcgcttcca gtgctctttc tgcagctgta
     1441 tcaatgatgt gccccctcag tattttcaac atctggatca taccggcaaa cgcgtggatg
     1501 cttatgaccg tcctgagctg tctctggggt cttatgaatt cttggctact gtagattact
     1561 gtaagaacaa caaattccct agtcctcctg ccttcatctt tatgattgac gtctcctaca
     1621 atgccatcag aactggtctt gttcggctcc tctgtgagga gctcaagtca ctcttagact
     1681 acttgcctag ggagggtgga gcagaagagt cagcaatccg ggttggcttt gtcacctata
     1741 ataaagtgct ccacttctac aatgtgaaga gctccttggc tcagccacag atgatggtcg
     1801 tatctgatgt ggctgacatg tttgtgccac tgctggatgg cttcctggtc aatgtcagcg
     1861 agtctcgggc cgttatcacc agcttattgg atcagattcc agaaatgttt gcagacacaa
     1921 gagagacaga gactgtgttt gctccagtta tccaggccgg gatggaagct ctgaaggccg
     1981 ccgagtgtgc aggaaagctg tttttgttcc acacgtcctt gcccatcgca gaggccccag
     2041 ggaagctgaa gaatagagat gacaggaagt tgatcaatac agacaaggag aagactctgt
     2101 ttcagcctca gacaggtacc tatcagactc tggccaaaga gtgtgtggcc caaggctgct
     2161 gtgtggacct cttcctcttc cctaaccaat atgtcgatgt ggccacactc tctgttgttc
     2221 cccagctcac tggaggctca gtctacaaat acgcctgctt ccaggtggag aatgaccagg
     2281 aacggttctt gagtgaccta cgtcgggatg tacagaaggt ggttggcttt gatgctgtca
     2341 tgcgggttcg gacaagcacc ggcatccgtg ctgtggattt ctttggagct ttctacatga
     2401 gcaatacaac agatgtggag ttggctggac tggatggcga caagaccgtg actgtggaat
     2461 tcaagcatga cgaccggctc aatgaagaga gtggagccct gctgcagtgt gccctgcttt
     2521 ataccagctg tgcagggcag cgtcggctcc gcatccacaa cctggccctc aactgctgca
     2581 cccagctggc tgacctgtat cgaaactgtg agactgacac gctcatcaac tacatggcca
     2641 agtttgcata ccgggctgtt gtgagtagcc ctgtgaagac tgtccgtgac actctcatca
     2701 cccagtgtgc ccagatcctg gcctgttaca gaaagaactg tgccagcccg tcttctgcgg
     2761 gacagttgat ccttcctgag tgcatgaagc tactcccagt ttacctgaac tgtgtgttga
     2821 agagtgacgt tctgcagcct ggagctgagg tcactactga tgatcgtgcc tatgttcgac
     2881 agctggtttc ctccatggat gtggctgaga ccaatgtctt cttctaccct cggctcctcc
     2941 cactgacaaa gtctcccctt gatagtacca ctgaaccacc agcagtccga gcatctgaag
     3001 aacgtttaag cagtggtgat atatatttgc tggaaaatgg actcaacctc tttgtctggg
     3061 tgggagcaag cgtccaacaa ggtgttgtcc agagcctttt caacgtctcc tccttcagtc
     3121 agatcaccag tggcttgagt gttctgccag ttctggataa tccactgtct aagaaagtgc
     3181 gaggcctcat cgatacctta cgggcccaga gaacgcggta catgaagctc atcgtggtca
     3241 aacaggaaga caagctagag atgctgttca agcacttcct ggtggaagac aagagcctaa
     3301 gtggaggtgc atcctatgtg gactttctct gccacatgca caaggagatt cggcagctgc
     3361 tgagctaaag caagagggtc agtggcagag ggtcccaggc cagcttccag gaagaacccc
     3421 aggatggcag agaaactggg acagttccat atcttataag tcatgtaagc tgacctcagt
     3481 tgacttcttt ggggggaggg cgagataaaa ggagacacct tctttctggg ctcaaatacc
     3541 ctaccacact ctgtcatgtc ctgctgatcg aaggtgcccc agaccccata ctctaccctt
     3601 tctcctgcta atcctgttgt aatgaatgta gtttccagtt cactgtatat gattcggtgt
     3661 tgggggtttg gaggcagcca ggccctggca caatgtgacc ctttggatca gcttccaaga
     3721 ggaaaggggc aagcaggaag aagtgggaat cccaggatta ttacaggagg cggtaaattc
     3781 agctccgtgt catcaacaac ttcctatatt agggataaaa tatacaggtg cacaagagct
     3841 ggggtacaga ccgtaggtgg tggagagtaa aggagttggt cctttggggg cctggtggtc
     3901 agtagcaaag tcatggctac tgaggatgga tgactagttg tctctctact tccactgtgc
     3961 gtgctctctc tcccctgcaa tgattggtga gcacttcgtg gacagaaaga agcacatagt
     4021 tagagatgaa tgagcctgga gactaaatcg caaagcatat taacacctag gggaagtagc
     4081 agcctccttt ccagatggag aagccccaat cctggatggt tctgtagaga gcctgatggt
     4141 caacttgcaa tacctcacag agccagccca catcccactc agctcccacg agaaacgttg
     4201 ttggagagag gcagagatgg caggagccct gtcctccgtg ccaggacttt actgggcttt
     4261 ggtactgact gagtggctga caagttatct tccaattcca attggctggg caggacaagg
     4321 gctaggaatg acggtggtca ggcttgcctg ctcccagccc aggatgcccc tgctatggac
     4381 ctttcatttc ttttcattgg tttatttttc aatgcatctt taatttgtaa agaaataaaa
     4441 taagatataa ccagtat
//
