LOCUS       NP_001102926            1095 aa            linear   ROD 23-MAR-2023
DEFINITION  protein transport protein Sec24C [Rattus norvegicus].
ACCESSION   NP_001102926 XP_001061137 XP_001061263 XP_001061319 XP_001061382
            XP_001061441 XP_001061501
VERSION     NP_001102926.1
DBSOURCE    REFSEQ: accession NM_001109456.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1095)
  AUTHORS   Adams,E.J., Chen,X.W., O'Shea,K.S. and Ginsburg,D.
  TITLE     Mammalian COPII coat component SEC24C is required for embryonic
            development in mice
  JOURNAL   J Biol Chem 289 (30), 20858-20870 (2014)
   PUBMED   24876386
REFERENCE   2  (residues 1 to 1095)
  AUTHORS   Montgomery TR, Steinkellner T, Sucic S, Koban F, Schuchner S, Ogris
            E, Sitte HH and Freissmuth M.
  TITLE     Axonal targeting of the serotonin transporter in cultured rat
            dorsal raphe neurons is specified by SEC24C-dependent export from
            the endoplasmic reticulum
  JOURNAL   J Neurosci 34 (18), 6344-6351 (2014)
   PUBMED   24790205
  REMARK    GeneRIF: Axonal delivery of serotonin transporter is contingent on
            recruitment of SEC24C in the endoplasmic reticulum.
REFERENCE   3  (residues 1 to 1095)
  AUTHORS   Bonnon C, Wendeler MW, Paccaud JP and Hauri HP.
  TITLE     Selective export of human GPI-anchored proteins from the
            endoplasmic reticulum
  JOURNAL   J Cell Sci 123 (Pt 10), 1705-1715 (2010)
   PUBMED   20427317
REFERENCE   4  (residues 1 to 1095)
  AUTHORS   Mancias JD and Goldberg J.
  TITLE     Structural basis of cargo membrane protein discrimination by the
            human COPII coat machinery
  JOURNAL   EMBO J 27 (21), 2918-2928 (2008)
   PUBMED   18843296
REFERENCE   5  (residues 1 to 1095)
  AUTHORS   Mancias JD and Goldberg J.
  TITLE     The transport signal on Sec22 for packaging into COPII-coated
            vesicles is a conformational epitope
  JOURNAL   Mol Cell 26 (3), 403-414 (2007)
   PUBMED   17499046
REFERENCE   6  (residues 1 to 1095)
  AUTHORS   Tang BL, Kausalya J, Low DY, Lock ML and Hong W.
  TITLE     A family of mammalian proteins homologous to yeast Sec24p
  JOURNAL   Biochem Biophys Res Commun 258 (3), 679-684 (1999)
   PUBMED   10329445
REFERENCE   7  (residues 1 to 1095)
  AUTHORS   Pagano A, Letourneur F, Garcia-Estefania D, Carpentier JL, Orci L
            and Paccaud JP.
  TITLE     Sec24 proteins and sorting at the endoplasmic reticulum
  JOURNAL   J Biol Chem 274 (12), 7833-7840 (1999)
   PUBMED   10075675
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474061.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001061382.1, XP_001061319.1, XP_001061441.1, XP_001061263.1,
            XP_001061501.1, XP_001061137.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC168663.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1095
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     Protein         1..1095
                     /product="protein transport protein Sec24C"
                     /note="SEC24 related gene family, member C; SEC24 family,
                     member C"
                     /calculated_mol_wt=118394
     Region          <7..305
                     /region_name="PHA03247"
                     /note="large tegument protein UL36; Provisional"
                     /db_xref="CDD:223021"
     Region          181..1091
                     /region_name="COG5028"
                     /note="Vesicle coat complex COPII, subunit SEC24/subunit
                     SFB2/subunit SFB3 [Intracellular trafficking and
                     secretion]"
                     /db_xref="CDD:227361"
     CDS             1..1095
                     /gene="Sec24c"
                     /coded_by="NM_001109456.1:81..3368"
                     /db_xref="GeneID:685144"
                     /db_xref="RGD:1597739"
ORIGIN      
        1 mnvnqsappv ppfgqnqpiy pgyhqsnygg qpgpaapatp ygayngpvpg yqqappqgvp
       61 rappcsgapp asaaqvpcgq ttygqfgqgd iqngpsstaq mprvpgsqqf gpplapvvsq
      121 pavlqpygpp ptstqvtaql aamqisgava qapppsglgy gpptslasas gnfpnsgpys
      181 typqsqappl sqaqghpgvq pplrsappla ssftspasgg prmpsmpgpl ppgqgfgslp
      241 vsqanrvssp pahalppgtq mtgppapppp mhspqqpgyq lqqngsfgpa rgpqpnyesp
      301 ypgaptfgtq pgppqplppk rldpdaipsp iqvieddrnn rgsepfvtgv rgqvpplvtt
      361 nflvkdqgna spryirctsy nipctsdmak qaqvplaavi kplarlppee aspyvvdhge
      421 sgplrcnrck aymcplmtfi eggrrfqcsf cscindvppq yfqhldhtgk rvdaydrpel
      481 slgsyeflat vdycknnkfp sppafifmid vsynairtgl vrllceelks lldylpregg
      541 aeesairvgf vtynkvlhfy nvksslaqpq mmvvsdvadm fvplldgflv nvsesravit
      601 slldqipemf adtretetvf apviqagmea lkaaecagkl flfhtslpia eapgklknrd
      661 drklintdke ktlfqpqtgt yqtlakecva qgccvdlflf pnqyvdvatl svvpqltggs
      721 vykyacfqve ndqerflsdl rrdvqkvvgf davmrvrtst giravdffga fymsnttdve
      781 lagldgdktv tvefkhddrl neesgallqc allytscagq rrlrihnlal ncctqladly
      841 rncetdtlin ymakfayrav vsspvktvrd tlitqcaqil acyrkncasp ssagqlilpe
      901 cmkllpvyln cvlksdvlqp gaevttddra yvrqlvssmd vaetnvffyp rllpltkspl
      961 dstteppavr aseerlssgd iyllenglnl fvwvgasvqq gvvqslfnvs sfsqitsgls
     1021 vlpvldnpls kkvrglidtl raqrtrymkl ivvkqedkle mlfkhflved kslsggasyv
     1081 dflchmhkei rqlls
//
