LOCUS       NM_001277235            2758 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus Sec23 homolog B, COPII coat complex component
            (Sec23b), mRNA.
ACCESSION   NM_001277235
VERSION     NM_001277235.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2758)
  AUTHORS   Yehia,L., Niazi,F., Ni,Y., Ngeow,J., Sankunny,M., Liu,Z., Wei,W.,
            Mester,J.L., Keri,R.A., Zhang,B. and Eng,C.
  TITLE     Germline Heterozygous Variants in SEC23B Are Associated with Cowden
            Syndrome and Enriched in Apparently Sporadic Thyroid Cancer
  JOURNAL   Am J Hum Genet 97 (5), 661-676 (2015)
   PUBMED   26522472
REFERENCE   2  (bases 1 to 2758)
  AUTHORS   Renella,R., Roberts,N.A., Brown,J.M., De Gobbi,M., Bird,L.E.,
            Hassanali,T., Sharpe,J.A., Sloane-Stanley,J., Ferguson,D.J.,
            Cordell,J., Buckle,V.J., Higgs,D.R. and Wood,W.G.
  TITLE     Codanin-1 mutations in congenital dyserythropoietic anemia type 1
            affect HP1{alpha} localization in erythroblasts
  JOURNAL   Blood 117 (25), 6928-6938 (2011)
   PUBMED   21364188
REFERENCE   3  (bases 1 to 2758)
  AUTHORS   Zhang,J., Wang,Y., Zhou,Y., Cao,Z., Huang,P. and Lu,B.
  TITLE     Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are
            potential interaction partners of testicular germ cell-specific
            protein GGN1
  JOURNAL   FEBS Lett 579 (2), 559-566 (2005)
   PUBMED   15642376
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ211753.1, SRR26643298.19155.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                JAXUCZ010000003.1  152392683-152392744
            63-297              JAXUCZ010000003.1  152395463-152395697
            298-355             JAXUCZ010000003.1  152397754-152397811
            356-442             JAXUCZ010000003.1  152400209-152400295
            443-679             JAXUCZ010000003.1  152402378-152402614
            680-765             JAXUCZ010000003.1  152402716-152402801
            766-910             JAXUCZ010000003.1  152403548-152403692
            911-1069            JAXUCZ010000003.1  152404338-152404496
            1070-1185           JAXUCZ010000003.1  152404833-152404948
            1186-1309           JAXUCZ010000003.1  152407109-152407232
            1310-1390           JAXUCZ010000003.1  152409168-152409248
            1391-1480           JAXUCZ010000003.1  152412309-152412398
            1481-1587           JAXUCZ010000003.1  152413285-152413391
            1588-1741           JAXUCZ010000003.1  152416466-152416619
            1742-1819           JAXUCZ010000003.1  152419597-152419674
            1820-1981           JAXUCZ010000003.1  152428456-152428617
            1982-2068           JAXUCZ010000003.1  152430180-152430266
            2069-2224           JAXUCZ010000003.1  152430675-152430830
            2225-2290           JAXUCZ010000003.1  152431304-152431369
            2291-2758           JAXUCZ010000003.1  152434346-152434813
FEATURES             Location/Qualifiers
     source          1..2758
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..2758
                     /gene="Sec23b"
                     /note="Sec23 homolog B, COPII coat complex component"
                     /db_xref="GeneID:362226"
                     /db_xref="RGD:1310699"
     exon            1..62
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            63..297
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..2380
                     /gene="Sec23b"
                     /note="Sec23 homolog B, coat complex II component"
                     /codon_start=1
                     /product="protein transport protein Sec23B"
                     /protein_id="NP_001264164.1"
                     /db_xref="GeneID:362226"
                     /db_xref="RGD:1310699"
                     /translation="MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTP
                     LKERPDLPPVQYEPVLCSRPTCKAILNPLCQVDYRAKLWACNFCFQRNQFPPAYAGIS
                     EVNQPAELMPQFSTIEYMIQRGARSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPP
                     DALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQEMLGLTKSAMPVQQVRP
                     GQPQEQSAVSSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGL
                     LEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKTPIRSWHDIEKDNARFMKKATKHYE
                     MLANRTATNGHCIDIYACALDQTGLLEMKCCPNLTGGLMVMGDSFNTSLFKQTFQRIF
                     SKDFNGDFRMAFGATLEVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKI
                     CGLDPSSTLGIYFEVVNQHNAPIPQGGRGAIQFVTQYQHSSTQKRIRVTTIARNWADA
                     QSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKED
                     PTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPI
                     LYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYEN
                     FKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQET
                     GAPILTDDVSLQVFMDHLKKLAVSSAS"
     exon            298..355
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            356..442
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            443..679
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            680..765
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            766..910
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1069
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1185
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1309
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1390
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1480
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1587
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..1741
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1819
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1981
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            1982..2068
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2224
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2290
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2758
                     /gene="Sec23b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttggctgt ggaagccgga gctgagctct gctgtccgtg gggcgcggaa ggctctgtcc
       61 agtttccttt tagaccatgg caacatatct ggaattcatt cagcagaatg aagaacgaga
      121 tggtgtgcgt ttcagttgga atgtgtggcc ttctagccga cttgaagcca caagaatggt
      181 tgttcccttg gcttgtctcc tcactccttt aaaagagcgc ccagacttac ctcctgtaca
      241 gtatgaacct gtgctttgca gtaggcctac ctgcaaagct attctcaatc cactttgtca
      301 agttgattac cgagcaaaac tttgggcctg caatttctgt tttcaaagaa atcagttccc
      361 cccagcatat gcaggcattt ctgaggtgaa ccagcctgct gaattgatgc cccagttctc
      421 cacaatcgag tacatgatcc agagaggtgc tcggtcccct ctgatctttc tctatgtggt
      481 tgacacgtgt ttggaagaag atgaccttca agcactcaaa gagtcgctgc agatgtctct
      541 gagtctcctt cctccagatg ccctggttgg tcttatcact tttgggagga tggtgcaggt
      601 tcatgagcta agctgtgaag gaatctccaa gagctatgtc ttccgaggga ccaaggattt
      661 aactgcaaag caaatacagg agatgctggg cctgaccaag tcagctatgc ctgtgcagca
      721 agtcagacct ggtcaacctc aggagcagtc tgctgtttcc agcagatttc tacagcccgt
      781 tcacaagatt gacatgaacc tcacagatct tcttggggag ctgcagaggg acccatggcc
      841 cgtaactcag gggaagagac cactgagatc cactggtgtt gctttgtcca ttgctgttgg
      901 cttgttggag ggtacattcc caaatactgg agccaggatc atgctgttca ctggtgggcc
      961 cccgacccaa ggacctggca tggtggttgg agatgaattg aagactccta ttcgttcctg
     1021 gcacgatatt gagaaagata atgcacggtt catgaaaaag gcaaccaagc attatgagat
     1081 gcttgctaat cgaactgcta caaatggtca ctgcattgat atttatgctt gtgcccttga
     1141 tcaaactgga cttctggaga tgaagtgctg tccaaatctt acaggaggcc tcatggtgat
     1201 gggagactca ttcaacacct ctctcttcaa gcagaccttc caaaggattt ttagtaaaga
     1261 cttcaacgga gatttcagaa tggcgtttgg tgctaccctg gaagtcaaga cctctcggga
     1321 actgaagatt gcaggtgcca ttggtccatg tgtgtctctg aatgtgaaag gaccatgtgt
     1381 gtcagaaaat gagctcggcg ttggtggcac aagtcagtgg aagatctgtg gcctggatcc
     1441 ttcgtctact cttggcatct actttgaagt tgtcaatcag cacaatgccc cgattcccca
     1501 gggaggcaga ggtgccatcc agtttgtcac tcagtatcag cattccagca ctcagaagcg
     1561 catccgagtg accaccattg cccgcaattg ggcagatgca cagagtcagc tgaggcacat
     1621 agaagcagcg tttgaccagg aggctgcagc agtcttgatg gcacggcttg gagtgttccg
     1681 ggcagagtca gaggaggggc ctgacgtgct ccggtggctg gatcgacaac tcatcagact
     1741 gtgtcagaag tttggacagt ataacaaaga agaccccacg tctttcaggc tgtcagactc
     1801 cttttctctg tatcctcagt tcatgttcca tctgaggaga tctccgtttc ttcaagtgtt
     1861 taacaacagt cctgacgagt cgtcctatta tagacaccat tttgcccggc aggatctgac
     1921 tcagtccctc atcatgatcc agcccattct ctactcttac tccttccacg gacccccaga
     1981 gcctgtactc ctggacagca gtagcattct agctgacaga attctgctga tggatacttt
     2041 cttccaaatt gtcatttacc ttggtgagac catagcccag tggcggaaag ctggctacca
     2101 ggacatgcct gagtatgaga acttcaagca ccttctgcag gcaccgctgg atgatgccca
     2161 agaaattctg caagcacgct tcccaatgcc acgatatatc aacacagagc acggtggcag
     2221 tcaggctcga ttcctgttgt ctaaagttaa tccttctcag acacacaata acctgtatgc
     2281 ttggggacag gaaactggag cgcccatcct gacagacgat gtcagcctgc aggtgttcat
     2341 ggatcatttg aagaagctgg ctgtgtccag tgcctcttaa gctagtagca cagcctagaa
     2401 gtggaagaaa atgctgtcag attgtgctca cattgttgat agtgtcctag catcattcac
     2461 ctttctggga gattctaata aataacccac ggcttttttt atatgtatgt cttcaggtta
     2521 tagtatgtct tcaggttata atttatttgt agtcctctct acctgttttc atatacatga
     2581 aattatatgt cataaatgtt ctgctaattg tagatgttac ttactttttg taccttaatg
     2641 ttttagagtc tataaaatca gagtttatgt atttttgact acttgtttaa gtgacagtct
     2701 taatgatcat aaaggaaata aatctggatg aggatggctt tggccaaaat aacactaa
//
