LOCUS       NM_022608               1595 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus SEC14-like lipid binding 3 (Sec14l3), mRNA.
ACCESSION   NM_022608 XM_001067306 XM_341244
VERSION     NM_022608.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Shan,L., Kawakami,T., Asano,S., Noritake,S., Yoshimoto,D.,
            Yamashita,K., Kikkawa,H., Kinoshita,M. and Matsubara,S.
  TITLE     Inverse relationship between Sec14l3 mRNA/protein expression and
            allergic airway inflammation
  JOURNAL   Eur J Pharmacol 616 (1-3), 293-300 (2009)
   PUBMED   19577556
  REMARK    GeneRIF: Sec14l3 expression is highly and inversely associated with
            the progression of airway inflammation.
REFERENCE   2  (bases 1 to 1595)
  AUTHORS   Merkulova,M., Huynh,H., Radchenko,V., Saito,K., Lipkin,V.,
            Shuvaeva,T. and Mustelin,T.
  TITLE     Secretion of the mammalian Sec14p-like phosphoinositide-binding p45
            protein
  JOURNAL   FEBS J 272 (21), 5595-5605 (2005)
   PUBMED   16262698
  REMARK    GeneRIF: Sec14p-like phosphoinositide-binding p45 protein and
            phosphoinositides may participate in the formation of the
            protective mucus on nasal epithelium.
REFERENCE   3  (bases 1 to 1595)
  AUTHORS   Mokashi,V., Singh,D.K. and Porter,T.D.
  TITLE     Rat supernatant protein factor-like protein stimulates squalene
            monooxygenase and is activated by protein kinase A
  JOURNAL   Biochem Biophys Res Commun 316 (3), 688-692 (2004)
   PUBMED   15033454
  REMARK    GeneRIF: SPF2 (supernatant protein factor-like protein), appears to
            be predominantly expressed in respiratory and epithelial tissues.
REFERENCE   4  (bases 1 to 1595)
  AUTHORS   Merkulova,M.I., Andreeva,S.G., Shuvaeva,T.M., Novoselov,S.V.,
            Peshenko,I.V., Bystrova,M.F., Novoselov,V.I., Fesenko,E.E. and
            Lipkin,V.M.
  TITLE     A novel 45 kDa secretory protein from rat olfactory epithelium:
            primary structure and localisation
  JOURNAL   FEBS Lett 450 (1-2), 126-130 (1999)
   PUBMED   10350070
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC162038.1.
            
            On or before Sep 7, 2008 this sequence version replaced
            XM_001067306.1, XM_341244.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC162038.1, AJ132352.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1595
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /note="SEC14-like lipid binding 3"
                     /db_xref="GeneID:64543"
                     /db_xref="RGD:620812"
     exon            1..79
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1228
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /note="rsec45; 45 kDa secretory protein; secretory
                     protein, 45kD; SEC14-like 3"
                     /codon_start=1
                     /product="SEC14-like protein 3"
                     /protein_id="NP_072130.1"
                     /db_xref="GeneID:64543"
                     /db_xref="RGD:620812"
                     /translation="MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRA
                     RNFDLQKSEAMLRKYMEFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPLWYDI
                     IGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGRKIETIVMIFDCEGLGL
                     KHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIV
                     VLGNSWKEGLLKLISPEELPAHFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKT
                     QYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQKAGEMT
                     EVLTSQRYNAHMVPEDGSLTCTEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQK
                     YDEELTPI"
     exon            80..155
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            156..199
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            200..259
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            260..448
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            449..544
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            545..605
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            606..689
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            690..796
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            797..936
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1106
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1583
                     /gene="Sec14l3"
                     /gene_synonym="Spf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttactgctc atcagtctca gcaccatgag tggccgagtt ggagacctga gccccaagca
       61 ggcagagacc ctggccaagt tccgagaaaa tgtccaggat gtgctgcccg ccctgccaaa
      121 ccctgatgac tattttcttc ttcgttggct ccgagctcgg aactttgacc tacagaaatc
      181 agaggccatg ctccgcaagt acatggagtt ccggaagacc atggacattg atcacatcct
      241 tgactggcag cccccagagg tgatccagaa gtacatgccc ggaggcctgt gtggctatga
      301 ccgggacggc tgccctttgt ggtatgacat catcgggcca ctggacccca aagggctgct
      361 tttctcagtc accaagcagg acctgttgaa gactaagatg agggactgtg aacgtatcct
      421 gcacgagtgt gacctgcaga cagagcggct ggggaggaag attgaaacca ttgtgatgat
      481 atttgactgt gaaggtctgg gactgaagca cttctggaaa cctctggtgg aagtgtacca
      541 ggagttcttt ggcctccttg aagagaatta cccagagacc ctgaagttca tgctcattgt
      601 gaaagccacc aaactgttcc ccgtgggcta caacctcatg aagccattcc tgagtgagga
      661 cacacggagg aagattgtag tgttgggaaa cagctggaaa gaaggtttgc tgaaactcat
      721 cagtcctgag gaactgcctg cccattttgg ggggacactc actgacccag atgggaatcc
      781 caaatgttta accaagatca actacggtgg ggagattccc aagtccatgt atgtgcgtga
      841 ccaggtgaag acccagtatg agcactcggt gcagattagc cgcggctcct cccatcaggt
      901 ggaatacgag atcctgttcc caggctgcgt cctcaggtgg cagttctcat ctgatggagc
      961 agacattggc tttggagttt tcctcaagac caagatgggg gagaggcaga aggcagggga
     1021 gatgaccgag gtgctaacca gccagcgcta caatgcccac atggtgcctg aggatgggag
     1081 cctcacctgc accgaggctg gtgtctatgt cctgcgcttt gacaacacct atagcttcgt
     1141 ccatgccaag aaggtcagct tcacggttga agtgcttctc ccagatgagg gcatgcagaa
     1201 gtacgatgag gagctcaccc ctatctaggt ggaccccccc acttctcaga gaccccacgc
     1261 tctgttttcc ctcttctctc ctttcattcc taaacctgat cattagtcgg gcttactctg
     1321 tgacaccagt gcgcagagga agagattgcc cggagaagat ttatctgctg tagtcaaatt
     1381 gcaaaatgac gaaaggttgg aggtataaag attgcaaaag agaaagaagc acaaggaaaa
     1441 gacagaagat gggtgtcact ggggtctaag aatagggaaa ggggggttgg ggatttagct
     1501 cagtggtaga gcgcttgcct agcaagcgca aggccctggg ttcggtcctc agctccaaaa
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
