LOCUS       NM_001006978            1297 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus SEC13 homolog, nuclear pore and COPII coat
            complex component (Sec13), mRNA.
ACCESSION   NM_001006978 XM_216257
VERSION     NM_001006978.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Wolfson,R.L., Chantranupong,L., Wyant,G.A., Gu,X., Orozco,J.M.,
            Shen,K., Condon,K.J., Petri,S., Kedir,J., Scaria,S.M.,
            Abu-Remaileh,M., Frankel,W.N. and Sabatini,D.M.
  TITLE     KICSTOR recruits GATOR1 to the lysosome and is necessary for
            nutrients to regulate mTORC1
  JOURNAL   Nature 543 (7645), 438-442 (2017)
   PUBMED   28199306
REFERENCE   2  (bases 1 to 1297)
  AUTHORS   Apelt,L., Knockenhauer,K.E., Leksa,N.C., Benlasfer,N.,
            Schwartz,T.U. and Stelzl,U.
  TITLE     Systematic Protein-Protein Interaction Analysis Reveals
            Intersubcomplex Contacts in the Nuclear Pore Complex
  JOURNAL   Mol Cell Proteomics 15 (8), 2594-2606 (2016)
   PUBMED   27194810
REFERENCE   3  (bases 1 to 1297)
  AUTHORS   Bruno,J., Brumfield,A., Chaudhary,N., Iaea,D. and McGraw,T.E.
  TITLE     SEC16A is a RAB10 effector required for insulin-stimulated GLUT4
            trafficking in adipocytes
  JOURNAL   J Cell Biol 214 (1), 61-76 (2016)
   PUBMED   27354378
REFERENCE   4  (bases 1 to 1297)
  AUTHORS   Bonnet,A. and Palancade,B.
  TITLE     Regulation of mRNA trafficking by nuclear pore complexes
  JOURNAL   Genes (Basel) 5 (3), 767-791 (2014)
   PUBMED   25184662
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1297)
  AUTHORS   Bar-Peled,L., Chantranupong,L., Cherniack,A.D., Chen,W.W.,
            Ottina,K.A., Grabiner,B.C., Spear,E.D., Carter,S.L., Meyerson,M.
            and Sabatini,D.M.
  TITLE     A Tumor suppressor complex with GAP activity for the Rag GTPases
            that signal amino acid sufficiency to mTORC1
  JOURNAL   Science 340 (6136), 1100-1106 (2013)
   PUBMED   23723238
REFERENCE   6  (bases 1 to 1297)
  AUTHORS   Loiodice,I., Alves,A., Rabut,G., Van Overbeek,M., Ellenberg,J.,
            Sibarita,J.B. and Doye,V.
  TITLE     The entire Nup107-160 complex, including three new members, is
            targeted as one entity to kinetochores in mitosis
  JOURNAL   Mol Biol Cell 15 (7), 3333-3344 (2004)
   PUBMED   15146057
REFERENCE   7  (bases 1 to 1297)
  AUTHORS   Enninga,J., Levay,A. and Fontoura,B.M.
  TITLE     Sec13 shuttles between the nucleus and the cytoplasm and stably
            interacts with Nup96 at the nuclear pore complex
  JOURNAL   Mol Cell Biol 23 (20), 7271-7284 (2003)
   PUBMED   14517296
REFERENCE   8  (bases 1 to 1297)
  AUTHORS   Fontoura,B.M., Blobel,G. and Matunis,M.J.
  TITLE     A conserved biogenesis pathway for nucleoporins: proteolytic
            processing of a 186-kilodalton precursor generates Nup98 and the
            novel nucleoporin, Nup96
  JOURNAL   J Cell Biol 144 (6), 1097-1112 (1999)
   PUBMED   10087256
REFERENCE   9  (bases 1 to 1297)
  AUTHORS   Shaywitz,D.A., Orci,L., Ravazzola,M., Swaroop,A. and Kaiser,C.A.
  TITLE     Human SEC13Rp functions in yeast and is located on transport
            vesicles budding from the endoplasmic reticulum
  JOURNAL   J Cell Biol 128 (5), 769-777 (1995)
   PUBMED   7876304
REFERENCE   10 (bases 1 to 1297)
  AUTHORS   Swaroop,A., Yang-Feng,T.L., Liu,W., Gieser,L., Barrow,L.L.,
            Chen,K.C., Agarwal,N., Meisler,M.H. and Smith,D.I.
  TITLE     Molecular characterization of a novel human gene, SEC13R, related
            to the yeast secretory pathway gene SEC13, and mapping to a
            conserved linkage group on human chromosome 3p24-p25 and mouse
            chromosome 6
  JOURNAL   Hum Mol Genet 3 (8), 1281-1286 (1994)
   PUBMED   7987303
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC084705.1.
            
            On Nov 22, 2004 this sequence version replaced XM_216257.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC084705.1, CF110576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1297
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /note="SEC13 homolog, nuclear pore and COPII coat complex
                     component"
                     /db_xref="GeneID:297522"
                     /db_xref="RGD:1359555"
     exon            1..35
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1001
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /note="SEC13-like protein 1; SEC13 homolog, nuclear pore
                     and COPII coating complex component; GATOR complex protein
                     SEC13; GATOR2 complex protein SEC13"
                     /codon_start=1
                     /product="protein SEC13 homolog"
                     /protein_id="NP_001006979.1"
                     /db_xref="GeneID:297522"
                     /db_xref="RGD:1359555"
                     /translation="MVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRN
                     GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWKEENGTWEKTHEHSGH
                     DSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAP
                     AVVPGSLIDQPSGQKPNYIKKFASGGCDNLIKLWREEEDGQWKEEQKLEAHSDWVRDV
                     AWAPSIGLPTSTIASCSQDGRVFIWTCDDASGNMWSPKLLHKFNDVVWHVSWSITANI
                     LAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASITEGQQNEQ"
     exon            36..80
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            81..196
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            197..348
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            349..482
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            483..616
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            617..740
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            741..887
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1274
                     /gene="Sec13"
                     /gene_synonym="Sec13l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccgaggct gtgagtcgcc gctgctgtag ctatggtgtc agtaattaac actgtggata
       61 cctctcatga ggacatgatt catgatgcgc agatggacta ttatggcacc cgcctagcaa
      121 cctgctcctc agataggtct gtcaaaattt ttgatgtgcg aaatggaggg cagatcctca
      181 tcgcagacct cagaggacat gaggggccag tgtggcaggt ggcctgggct caccccatgt
      241 atggcaatat cctggcttcc tgttcctatg accggaaagt cattatctgg aaggaggaaa
      301 atggcacttg ggaaaagacc catgagcact caggacatga ctcctcagtg aactctgttt
      361 gctgggcccc tcatgactat ggcctgatcc tggcctgtgg gagttcagat ggtgccatct
      421 cgctgctgac ttatacaggg gaaggccagt gggaagtgaa gaagattaac aatgctcaca
      481 cgattggctg taatgctgtc agttgggccc cagctgttgt gcctggaagc cttatagacc
      541 aaccatccgg acagaaaccc aattacatca agaagtttgc atcaggtggc tgtgacaatc
      601 tcatcaagtt gtggagggaa gaggaggatg gccagtggaa ggaggagcaa aagctagagg
      661 cacacagtga ctgggttcga gacgttgcct gggccccctc cattggcttg cccaccagca
      721 ccattgccag ctgctctcag gatgggcgag tgtttatttg gacttgtgat gacgcctcag
      781 gcaatatgtg gtcacctaaa ctcctacaca agttcaatga tgtcgtgtgg cacgtgagct
      841 ggtccatcac agcaaatatc ctggctgtgt caggtggaga caataaggtg accctgtgga
      901 aagagtcggt ggatggacag tgggtgtgca tcagtgatgt caacaagggc cagggttctg
      961 tgtcagcctc catcacagag ggccaacaga atgagcaatg acaacacagg cagcctggtc
     1021 ttcctgttac ctattctgga acaacctcca aacaactggg aagagtcatc ccactgctac
     1081 caaggagtgc ccacacatgc agcactgggt gttcacctgc cttactggga ttccatgtgt
     1141 tcagtaattt aatgtccatc tgaaagtatt catgtaagga acaaatgact attattttta
     1201 agtatttttg gccattttta actatctttt ggttcaggct gtttccaagg taataaaatc
     1261 atattgcata gaaaaaaaaa aaaaaaaaaa aaaaaaa
//
