LOCUS       NM_153628                677 bp    mRNA    linear   ROD 12-DEC-2024
DEFINITION  Rattus norvegicus SEC11 homolog C, signal peptidase complex subunit
            (Sec11c), mRNA.
ACCESSION   NM_153628
VERSION     NM_153628.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Kalies,K.U. and Hartmann,E.
  TITLE     Membrane topology of the 12- and the 25-kDa subunits of the
            mammalian signal peptidase complex
  JOURNAL   J Biol Chem 271 (7), 3925-3929 (1996)
   PUBMED   8632014
REFERENCE   2  (bases 1 to 677)
  AUTHORS   Shelness,G.S., Lin,L. and Nicchitta,C.V.
  TITLE     Membrane topology and biogenesis of eukaryotic signal peptidase
  JOURNAL   J Biol Chem 268 (7), 5201-5208 (1993)
   PUBMED   8444896
REFERENCE   3  (bases 1 to 677)
  AUTHORS   Evans,E.A., Gilmore,R. and Blobel,G.
  TITLE     Purification of microsomal signal peptidase as a complex
  JOURNAL   Proc Natl Acad Sci U S A 83 (3), 581-585 (1986)
   PUBMED   3511473
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB022714.2.
            
            On Aug 31, 2012 this sequence version replaced NM_153628.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB022714.2, SRR8487230.150498.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-677               AB022714.2         2-678
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..677
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /note="SEC11 homolog C, signal peptidase complex subunit"
                     /db_xref="GeneID:266758"
                     /db_xref="RGD:628665"
     exon            1..142
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..634
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /EC_number="3.4.21.89"
                     /note="SEC11-like protein 3; SPase 21 kDa subunit;
                     microsomal signal peptidase 21 kDa subunit; Sec11-like 3;
                     signal peptidase 21kDa subunit"
                     /codon_start=1
                     /product="signal peptidase complex catalytic subunit
                     SEC11C"
                     /protein_id="NP_705892.1"
                     /db_xref="GeneID:266758"
                     /db_xref="RGD:628665"
                     /translation="MVRAGAVGTHLPTSSLDIFGDLRKMNKRQLYYQVLNFAMIVSSA
                     LMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGR
                     DIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPY
                     VGMVTIIMNDYPKFKYALVAVMGAYVLLKRES"
     exon            143..252
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
     exon            253..402
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
     exon            403..522
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
     exon            523..580
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
     exon            581..677
                     /gene="Sec11c"
                     /gene_synonym="Sec11l3; Spc21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccgagtgt gacagaccga gccggccggc cgcctgggcc cccagagacc ccgccatggt
       61 tcgtgcgggc gccgtgggga cgcatctccc cacgtccagc ctggacatct ttggggactt
      121 gaggaagatg aacaaacgac agctttacta ccaggtccta aactttgcca tgattgtgtc
      181 ttctgcgctc atgatatgga aaggcttaat tgtgctcacg ggcagtgaga gtcccatcgt
      241 ggtggtactg agtggcagta tggagccggc ctttcacagg ggagatctgc tgttcctcac
      301 aaatttccgg gaggatccca tcagagctgg tgaaatagtt gtttttaaag ttgaaggaag
      361 agacattccg atagttcaca gagtaatcaa ggttcatgaa aaagataatg gagacatcaa
      421 gtttctgact aaaggagata ataatgaagt tgatgatcga ggcttgtaca aagaaggcca
      481 gaactggctg gagaagaagg acgtggtagg aagagctcga gggttcttac catatgttgg
      541 catggtcacc attataatga acgactatcc taagttcaag tacgctcttg tggctgtgat
      601 gggcgcatac gtgttactga aacgtgaatc ctaacatgag aagcagttcc tgggaccaga
      661 ctgaaacgaa ttctgtc
//
