LOCUS       NM_001108336            1378 bp    mRNA    linear   ROD 20-AUG-2024
DEFINITION  Rattus norvegicus serine dehydratase-like (Sdsl), mRNA.
ACCESSION   NM_001108336 XM_001079897 XM_341089
VERSION     NM_001108336.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Katane,M., Nakasako,K., Yako,K., Saitoh,Y., Sekine,M. and Homma,H.
  TITLE     Identification of an l-serine/l-threonine dehydratase with
            glutamate racemase activity in mammals
  JOURNAL   Biochem J 477 (21), 4221-4241 (2020)
   PUBMED   33079132
REFERENCE   2  (bases 1 to 1378)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079897.1, XM_341089.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132308,
                              SAMEA5756307 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..1378
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /note="serine dehydratase-like"
                     /db_xref="GeneID:360816"
                     /db_xref="RGD:1309192"
     exon            1..241
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            242..435
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..1251
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /EC_number="4.3.1.17"
                     /EC_number="4.3.1.19"
                     /EC_number="5.1.1.3"
                     /note="L-serine dehydratase-like; L-serine deaminase;
                     glutamate racemase; L-threonine dehydratase; L-serine
                     dehydratase/L-threonine deaminase"
                     /codon_start=1
                     /product="serine dehydratase-like"
                     /protein_id="NP_001101806.1"
                     /db_xref="GeneID:360816"
                     /db_xref="RGD:1309192"
                     /translation="MEGASAECVRAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIA
                     GSFKIRGIGHFCQQMAKRGCRHLVCSSGGNAGIAAAYSAQKLGIPVTIVLPESTSKQV
                     VRRLEGEGAEVQLTGKVWDEANVRAQELATRDGWVNVSPFDHPLIWEGNASLVRELKE
                     SLRTPPGAVVLAVGGGGLLAGVVAGLLEVGWQHVPIVAMETRGAHSFNAALLAGRLVT
                     LPDITSVARSLGAKTVAARTLECAKECEVLSEVVEDREAVRAVQRFLDDERMLVEPAC
                     GAALAAVYSGILGRLQTEGRLSPALDSVVVIVCGGNNISSQQLQELKTQLNCS"
     exon            436..475
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            476..615
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            616..704
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            705..932
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1057
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1378
                     /gene="Sdsl"
                     /gene_synonym="Sdhl; TDH"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagcacgg gtcattcatg agccgtgagc tgcatgagga aggcagagag ggttgcatat
       61 ccccacgagt tcatcttgat cactttttgt tgtgagtcct caccaggacc ccagaatcaa
      121 gagctgtccc tttaacaagg aggaggggcc agggcctgat agcggaagct gatctggtag
      181 cctgtgagtt cagattgatc ctggctgggc tgtgctggtc ttggactgtc tttcggggaa
      241 ggtcgtcagc gttctgttgg aatggaggga gcctcggcag agtgtgtcag ggcagagcct
      301 ttccacaggg tcacacccct gctggagagc tgggcgctgt ctcaggtggc aggcatgcct
      361 gtcttcctca aatatgagaa cgtgcagata gctggctcct ttaagatccg gggcatcgga
      421 catttctgtc agcagatggc caagagggga tgcagacatc tggtgtgctc ctcagggggc
      481 aacgcaggca ttgcggccgc atactccgct cagaagctgg gcatccccgt caccatcgtg
      541 ctcccagaga gcacctccaa gcaggtggtg aggcggctgg agggagaggg ggccgaggtc
      601 cagctgactg ggaaggtctg ggatgaagcc aatgtaaggg cacaagaact ggccaccagg
      661 gacggctggg tgaacgtctc cccgtttgac catcccctga tatgggaagg caatgccagc
      721 ctagtgcggg agctcaagga gtccctgagg acgcctccag gtgccgtggt gctggccgtg
      781 gggggtggag ggctcctggc cggtgtggtt gctggcttac tggaggtagg ctggcagcat
      841 gtgcccatcg ttgccatgga gacccggggg gcacacagtt tcaacgcggc tttgctggcg
      901 ggcaggctgg tcactctgcc agacatcacc agcgtagcca ggagcctggg agccaagact
      961 gtggctgcac ggaccttgga gtgtgcaaag gagtgtgaag tcctctctga ggtggtagaa
     1021 gaccgggagg ctgtcagagc tgtgcagagg ttcctggacg atgagcgcat gctggtggag
     1081 cctgcctgcg gtgctgccct ggctgctgtc tactcaggca tcctggggag gctccagact
     1141 gagggccgcc tgagccctgc cctggattcc gtcgtggtca tcgtgtgtgg tggcaacaac
     1201 atcagtagcc aacagcttca ggagctgaaa acacagctga actgcagctg aaggatccca
     1261 gggacctcgg aggctactgg acaccttggt cctgtcctct tccttcaggc agccctcctg
     1321 gattgctccc tgtggctccc tgcagtccaa tgaataaacc tgcctgactg gagcatgt
//
