LOCUS       NM_001106634            1398 bp    mRNA    linear   ROD 18-MAR-2025
DEFINITION  Rattus norvegicus short chain dehydrogenase/reductase family 16C,
            member 5 (Sdr16c5), transcript variant 2, mRNA.
ACCESSION   NM_001106634 XM_001069656 XM_216325
VERSION     NM_001106634.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1398)
  AUTHORS   Takahashi,Y., Moiseyev,G., Farjo,K. and Ma,J.X.
  TITLE     Characterization of key residues and membrane association domains
            in retinol dehydrogenase 10
  JOURNAL   Biochem J 419 (1), 113-122 (2009)
   PUBMED   19102727
REFERENCE   2  (bases 1 to 1398)
  AUTHORS   Lee,S.A., Belyaeva,O.V. and Kedishvili,N.Y.
  TITLE     Biochemical characterization of human epidermal retinol
            dehydrogenase 2
  JOURNAL   Chem Biol Interact 178 (1-3), 182-187 (2009)
   PUBMED   18926804
REFERENCE   3  (bases 1 to 1398)
  AUTHORS   Markova,N.G., Pinkas-Sarafova,A. and Simon,M.
  TITLE     A metabolic enzyme of the short-chain dehydrogenase/reductase
            superfamily may moonlight in the nucleus as a repressor of promoter
            activity
  JOURNAL   J Invest Dermatol 126 (9), 2019-2031 (2006)
   PUBMED   16691198
REFERENCE   4  (bases 1 to 1398)
  AUTHORS   Matsuzaka,Y., Okamoto,K., Tsuji,H., Mabuchi,T., Ozawa,A., Tamiya,G.
            and Inoko,H.
  TITLE     Identification of the hRDH-E2 gene, a novel member of the SDR
            family, and its increased expression in psoriatic lesion
  JOURNAL   Biochem Biophys Res Commun 297 (5), 1171-1180 (2002)
   PUBMED   12372410
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473984.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_216325.4, XM_001069656.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMN06621351
                              [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1398
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..1398
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /note="short chain dehydrogenase/reductase family 16C,
                     member 5"
                     /db_xref="GeneID:297805"
                     /db_xref="RGD:1565999"
     exon            1..552
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
     CDS             220..1149
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /EC_number="1.1.1.105"
                     /note="epidermal retinal dehydrogenase 2; retinal short
                     chain dehydrogenase reductase 2"
                     /codon_start=1
                     /product="epidermal retinol dehydrogenase 2"
                     /protein_id="NP_001100104.1"
                     /db_xref="GeneID:297805"
                     /db_xref="RGD:1565999"
                     /translation="MPCNLESAKDLLVFLGKSLLSILEALLSHVISKPRKNVAGEVVL
                     ITGAGSGLGRLLALQFARLGSVLVLWDVNKETNEETRQIAQEAGAIRVHAYTCDCSQR
                     EEVYRVADQVKKEVGDVSILINNAGIVTGRKFLDCPDDLMEKSLDVNFKAHLWMYKAF
                     LPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFVETLAQKQRGIKT
                     TIVCPFFIKTGMFEGCTTKCPNLLPILDPEYAVRKIVDAILQEQLYLYMPKFLYFIMF
                     LKSFLPIKTGILIADYLGLFHVMDGFTGQKKKS"
     exon            553..684
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
     exon            685..784
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
     exon            785..929
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1055
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1398
                     /gene="Sdr16c5"
                     /gene_synonym="Rdhe2; RGD1565999"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaatgtcgtt atctgtgaca catagctggc atgcagatct gaatggaact tgagagccat
       61 gtgtagatat tgtgccagat atcgtacatc actgtggttc ctgcctgctc ctgagttcag
      121 tatcctcagc atctggaaag agcaactcta tcacattctt ttctttcaga aaagggaact
      181 gagaaaactc tctcttgctt taaaggtgtt ggccagaaca tgccttgcaa cctggaatca
      241 gcgaaggact tgcttgtttt cttagggaag tcactgttga gtattttgga ggctctactt
      301 tctcatgtca tctcaaaacc acggaagaat gttgctggcg aagtagtcct catcacaggt
      361 gctgggagtg gactcggaag gcttttagca ttgcagttcg cccgcctggg atcagtgctc
      421 gttctttggg atgtgaacaa ggagacaaat gaggagaccc gtcagatagc tcaggaagca
      481 ggagccatca gagtgcatgc ctacacctgt gactgcagcc agagggaaga agtatacaga
      541 gtggccgacc aggttaagaa agaagttggt gacgtctcta tcctcatcaa caatgctggc
      601 attgtaacag gcagaaagtt cctcgattgc ccagatgacc tcatggaaaa gtcacttgat
      661 gtcaatttca aagcacattt atggatgtat aaagcctttc tacctgccat gattgctaac
      721 aaccatggcc atttggtttg catttcaagt tcggctggat tgattggagt aaatgggctg
      781 tcagactatt gtgcaagtaa attcgcagcc cttggatttg cagaatctat gtttgtcgaa
      841 acacttgccc aaaaacaaag ggggatcaaa actactattg tgtgcccatt ctttataaaa
      901 actggaatgt ttgaaggttg cactactaag tgtcctaatc tgttaccaat tctggatcca
      961 gaatatgcag ttaggaaaat agtagatgct atccttcagg agcagctgta cttgtatatg
     1021 cccaagtttt tatacttcat aatgttttta aaaagcttct tgcccatcaa gacaggaata
     1081 cttatagctg actacctagg actctttcat gtgatggatg gcttcactgg tcaaaagaag
     1141 aaatcttaat gataacccct atgccctgtg ttttctgaga cccattgcta cgtcaggctt
     1201 acttcaaaga agaaaggtat ttctgtccga cagaacccaa aaacaaatat gttctactgt
     1261 ggaccatgat ccttccagtg tcatttgaat acaatgttac tgttttttct tttgttgtcg
     1321 ttgttgttgt tgaatgtatt ttttgtttag ttttggaaaa taaaagtagc tctttgtcat
     1381 tcccacttca acaactat
//
