LOCUS       NM_001399406             850 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus succinate dehydrogenase complex assembly factor 4
            (Sdhaf4), transcript variant 2, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001399406 XM_003750670
VERSION     NM_001399406.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 850)
  AUTHORS   Van Vranken,J.G., Bricker,D.K., Dephoure,N., Gygi,S.P., Cox,J.E.,
            Thummel,C.S. and Rutter,J.
  TITLE     SDHAF4 promotes mitochondrial succinate dehydrogenase activity and
            prevents neurodegeneration
  JOURNAL   Cell Metab 20 (2), 241-252 (2014)
   PUBMED   24954416
REFERENCE   3  (bases 1 to 850)
  AUTHORS   Yang,I.V., Wade,C.M., Kang,H.M., Alper,S., Rutledge,H.,
            Lackford,B., Eskin,E., Daly,M.J. and Schwartz,D.A.
  TITLE     Identification of novel genes that mediate innate immunity using
            inbred mice
  JOURNAL   Genetics 183 (4), 1535-1544 (2009)
   PUBMED   19805818
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 7, 2022 this sequence version replaced XM_003750670.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK839092.1, FM058019.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676810 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-253               JAXUCZ010000009.1  33912561-33912813   c
            254-403             JAXUCZ010000009.1  33910702-33910851   c
            404-850             JAXUCZ010000009.1  33904667-33905113   c
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q13"
     gene            1..850
                     /gene="Sdhaf4"
                     /note="succinate dehydrogenase complex assembly factor 4"
                     /db_xref="GeneID:685888"
                     /db_xref="RGD:1588998"
     exon            1..253
                     /gene="Sdhaf4"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..513
                     /gene="Sdhaf4"
                     /note="isoform 2 is encoded by transcript variant 2;
                     succinate dehydrogenase assembly factor 4, mitochondrial"
                     /codon_start=1
                     /product="succinate dehydrogenase assembly factor 4,
                     mitochondrial isoform 2"
                     /protein_id="NP_001386335.1"
                     /db_xref="GeneID:685888"
                     /db_xref="RGD:1588998"
                     /translation="MRGRRLRDRAGRGGCRSIRGAWRRGRWFSRSARLLGSSLLNHSL
                     RKKSSQEGKPEPSKQALKKSKLPVGRFDSLDDSPEERDPLQKFPDDVNPVTKEKGGPR
                     GPEPTRYGDWERKGRCIDF"
     exon            254..403
                     /gene="Sdhaf4"
                     /inference="alignment:Splign:2.1.0"
     exon            404..850
                     /gene="Sdhaf4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgtgcgct gacgctgtgc gagccggcgg tatggtctcc accattcttt ccgtgtcacg
       61 gatggctttc gtctggagag caacaagtaa ggcagtccgc ccgggatccg gagagttggg
      121 ggcccgctga ggaagccgag ttccgaaatg cgagggcgca ggctcagaga ccgggccggc
      181 cgcggtggct gcagaagcat tcgcggtgct tggcgtaggg gcaggtggtt ttcgagaagc
      241 gcccggctct taggatcatc tcttctgaat cactctttga ggaaaaagag ttctcaagaa
      301 ggaaagcctg agccttcaaa gcaagccctt aagaaatcaa agctgccagt tggtcgtttt
      361 gactcactgg acgattcacc agaggagaga gacccactgc agaagtttcc agatgatgtc
      421 aatccagtta ccaaagaaaa aggtggaccc aggggcccag agcctacacg atacggagac
      481 tgggaacgga aaggacgctg tattgacttt taagtcacgc cgtctcggga ctgcagagtc
      541 atttcctgaa ttacttactt catgttgttt tctgtatcct ctaagtgtga tatttccatc
      601 gtatgtctta aaatgcacgt ggtagcttcg aggagcaaag gctgcttata gatcaggaac
      661 atggaaacat ttttccatta gtgtgttaac ttcaacttaa acatgtcagg gcagagagcc
      721 tgtgatgaga gctgcaagcc tttgcagtga ttttttatca tcatcatcat catcattatt
      781 attattatta ttattattat ttaatcagtt gcttataaaa tacacatgtt aataaatacc
      841 tcttgttaga
//
