LOCUS       NM_001024970            3146 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus SDE2 telomere maintenance homolog (Sde2), mRNA.
ACCESSION   NM_001024970
VERSION     NM_001024970.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3146)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 3146)
  AUTHORS   Jo,U., Cai,W., Wang,J., Kwon,Y., D'Andrea,A.D. and Kim,H.
  TITLE     PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response
            to Replication Stress
  JOURNAL   PLoS Genet 12 (12), e1006465 (2016)
   PUBMED   27906959
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3146)
  AUTHORS   Hong,S.J., Li,H., Becker,K.G., Dawson,V.L. and Dawson,T.M.
  TITLE     Identification and analysis of plasticity-induced late-response
            genes
  JOURNAL   Proc Natl Acad Sci U S A 101 (7), 2145-2150 (2004)
   PUBMED   14766980
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001024970.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.1658124.1,
                                           SRR26360190.140657.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000013.1  95110663-95110850
            189-306             JAXUCZ010000013.1  95115273-95115390
            307-418             JAXUCZ010000013.1  95116051-95116162
            419-588             JAXUCZ010000013.1  95117500-95117669
            589-703             JAXUCZ010000013.1  95118883-95118997
            704-1193            JAXUCZ010000013.1  95120083-95120572
            1194-3146           JAXUCZ010000013.1  95124977-95126929
FEATURES             Location/Qualifiers
     source          1..3146
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q26"
     gene            1..3146
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /note="SDE2 telomere maintenance homolog"
                     /db_xref="GeneID:289315"
                     /db_xref="RGD:1305572"
     exon            1..188
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1415
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /note="UPF0667 protein C1orf55 homolog; protein SDE2
                     homolog; replication stress response regulator SDE2"
                     /codon_start=1
                     /product="UBL fusion protein SDE2"
                     /protein_id="NP_001020141.2"
                     /db_xref="GeneID:289315"
                     /db_xref="RGD:1305572"
                     /translation="MAEAAVLAWVRGPGTAWKALPCASVGCSVRDVIYRHCEEQEIPV
                     ECFFVKCNGVLVAAGDKVCHGAVYSLEPRLRGGKGGFGSMLRALGAQIEKTTNREACR
                     DLSGRRLRDVNHEKAMAEWVKQQAEREAEKEQRRLERLQRKLAEPAHCFASPDYQRQC
                     HEMAERLEDSVLKGMQAASSKVVSAEVTETRKRPNRSKTDQGAGAKKKRCFWLGMEGL
                     EAAEGSSTGSSDDSEDDDHEDAPGTSGPSCCARENGSDGGEVAADSPGSVQSSGSGTR
                     SESPKELQNPMTEPGQGILENTGTEPGETSTREHNERKTVTVTETEETPARKETESPE
                     PTEKGQETGVIGEDRAAMALSGEDRKSIPAATPEGSNSGDTALGVEALDLSAFSCAAE
                     LELLGLERLKCALMALGLKCGGTLQERAARLFSVRGLSKELIDPTLFAKPSKGKKK"
     exon            189..306
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     exon            307..418
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     exon            419..588
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     exon            589..703
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     exon            704..1193
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..3146
                     /gene="Sde2"
                     /gene_synonym="RGD1305572"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggatgcga ccggaaggtt gtgtcgccta gtgcgggtcg cggtctagag gttccgtcac
       61 caaacgaaat ggcggaggct gctgtgctgg cgtgggttcg cggccccggt accgcgtgga
      121 aggcgctacc gtgtgcctcg gtcgggtgct cagtgcgcga tgtaatctac cgacactgcg
      181 aagaacagga aattcctgtg gaatgcttct ttgtgaagtg caatggagtc ctcgttgctg
      241 ctggtgacaa ggtgtgccat ggagctgtgt acagtttgga gcccaggctt cgagggggca
      301 aaggaggttt cgggtctatg cttcgagcac ttggtgcaca gattgaaaag acaaccaatc
      361 gagaagcctg ccgggatctc agtgggagga gattacgaga tgtcaatcat gagaaagcga
      421 tggccgagtg ggtaaaacag caagctgagc gagaggctga aaaggagcaa aggcgcctgg
      481 agagactgca gcgaaagctt gcagagcctg cacactgctt tgccagccct gactaccaga
      541 ggcagtgcca tgaaatggct gagcgtctgg aggattcagt cctcaaaggt atgcaggctg
      601 cctccagcaa ggtggtgtca gcagaggtca cggagactcg aaaacggcct aacaggtcaa
      661 agacagacca gggagctggt gcaaagaaaa agaggtgctt ttggttgggc atggaaggac
      721 tggaggctgc cgagggatcc agtactggca gttcagatga cagtgaagat gatgaccatg
      781 aagatgctcc tgggacctcg gggcctagct gctgtgcccg ggaaaatggc agtgatggtg
      841 gggaggtggc agcagactct cctggcagtg ttcagagctc aggatctggt acacgctctg
      901 agtcgcctaa agagcttcag aaccccatga ctgagcctgg gcagggcatt ttggagaaca
      961 caggaactga gccaggagag acatctacca gggagcacaa tgagaggaag acggtcacag
     1021 tcacagaaac agaggagacc ccagcaagga aggaaacaga gagtcccgag cccacagaaa
     1081 agggccaaga gacaggagtg attggtgaag acagagctgc catggctttg tctggagaag
     1141 acaggaaaag catccctgct gctaccccag agggaagcaa ctcaggagac acggctcttg
     1201 gtgtggaagc tctggatctg tcggcattca gctgtgcagc cgagttggag ttgctgggtt
     1261 tggagaggct caagtgtgca ctgatggccc ttggactgaa gtgcggggga accctgcagg
     1321 agcgtgcggc cagactcttc tctgtcagag gcctctcaaa ggagctcatt gacccaactt
     1381 tatttgccaa gccttcaaaa gggaagaaga agtgaatttt ctcagcactc tcctggtgtt
     1441 cgacacttct tccagtgtga tggacttgtg gccaatgttc cttttgatac taaaagccag
     1501 ttttttaata attcagttct gattagtctc ttttcaatgg tacctgggct tgaggttttc
     1561 attggaggag aaaactttgt atcttattct ttctggtatt tttgtaagag acttactcta
     1621 taggccaggc tcaccaagaa ctgtgtagtt cactttggtc tgaaactggc agtgatcctc
     1681 ctgtctcagg catgagccac tgagcctgct ttgtcagagg tttatacatt tctttggctt
     1741 tatatattgt gtcatttggg taagatgttt ccaagaattc atttgtgtaa cccacagcag
     1801 tcaggtttat agacacggct attcataact tccattttaa aaacctagta tagtgtgtgt
     1861 taccaggggt ggagctagcc aggcttccca cacgggattt ttatttcagc tggggggcct
     1921 gtctattttg tttagttttc aaagaatcag atttttggct ttgtgggttt tctcagttgt
     1981 cgttgatctc tttggctttt tttttttttt ttttttttgt tcgagctggg gacagaaccc
     2041 agggccttgc gcttcctagg taagcgctat accactgagc taaatcccta gcccgatctc
     2101 tttggctttt gagtttatat ttcctctcct acatgccttg catttacttt atcatctttc
     2161 tttagctccc taagtcttag atcaccaatt agagatttta tttttattat tacttttagt
     2221 atattaccca attagtgagt gtttgtattt tctctaaatg ttttattgat actgactttt
     2281 caggacagaa ggtaccctgt atcctcttta tgactgacct aggataggat ctgacgatct
     2341 gtgctgtgtg cacattctca ccgagcacac actcagtggg cagcaggctg tgtgcgagaa
     2401 cgcctgtgag tggttggcca gctcattcag gtgaccagcc tttgctggtt tattttcata
     2461 agaactaaga gaaaactcaa atctcaatta tgattgtggg aattgccccc cctttttaga
     2521 taaaaataac ttaattggcg tttgctaagt tttcagtttt atattaatat agtgatctta
     2581 tatatgtttc tgcattgcct taaaatgtct gtctctgatg ggtttgggat ttttttccca
     2641 tctgacaatt cacacatgga tacagcgtgt cctgatctgg tccaccgtgc ttctttaatt
     2701 cttccgtttt tactttatat cttgaagcta ctgttaggtc ttactttctc cttcttattg
     2761 aacggttgat cgtgaaattc cttcctctct gggtttcctg ttcaccacgt attatctgaa
     2821 gcacagccct ccccctccag ctttcacctc gtctccacag tgcgcggttc tgtccatttc
     2881 ctctttcctg ctccttctgt ctacagtggg tgtctgcaga ctgcacgtta ttgtctcgaa
     2941 tttgtgtctg ttctatcacc atcaccatca ccatcaccct catcatctgg gccctgtctc
     3001 tgatgatggg tcagcggtga gtcacaatca taacattttc tttgggggtg tttcaggcat
     3061 ggtctactct tctgccttgt agtgtggtga gcttcatggt tttgtaaatt tattctgtta
     3121 attaaatttg gaaacatttt aagcaa
//
