LOCUS       NM_177929               2534 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus SHH signaling and ciliogenesis regulator SDCCAG8
            (Sdccag8), mRNA.
ACCESSION   NM_177929
VERSION     NM_177929.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Dharmat,R., Eblimit,A., Robichaux,M.A., Zhang,Z., Nguyen,T.T.,
            Jung,S.Y., He,F., Jain,A., Li,Y., Qin,J., Overbeek,P., Roepman,R.,
            Mardon,G., Wensel,T.G. and Chen,R.
  TITLE     SPATA7 maintains a novel photoreceptor-specific zone in the distal
            connecting cilium
  JOURNAL   J Cell Biol 217 (8), 2851-2865 (2018)
   PUBMED   29899041
REFERENCE   2  (bases 1 to 2534)
  AUTHORS   Airik,R., Schueler,M., Airik,M., Cho,J., Ulanowicz,K.A.,
            Porath,J.D., Hurd,T.W., Bekker-Jensen,S., Schroder,J.M.,
            Andersen,J.S. and Hildebrandt,F.
  TITLE     SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is
            Required for Hedgehog Signaling
  JOURNAL   PLoS One 11 (5), e0156081 (2016)
   PUBMED   27224062
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2534)
  AUTHORS   Insolera,R., Shao,W., Airik,R., Hildebrandt,F. and Shi,S.H.
  TITLE     SDCCAG8 regulates pericentriolar material recruitment and neuronal
            migration in the developing cortex
  JOURNAL   Neuron 83 (4), 805-822 (2014)
   PUBMED   25088364
REFERENCE   4  (bases 1 to 2534)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   5  (bases 1 to 2534)
  AUTHORS   Otto,E.A., Hurd,T.W., Airik,R., Chaki,M., Zhou,W., Stoetzel,C.,
            Patil,S.B., Levy,S., Ghosh,A.K., Murga-Zamalloa,C.A., van
            Reeuwijk,J., Letteboer,S.J., Sang,L., Giles,R.H., Liu,Q.,
            Coene,K.L., Estrada-Cuzcano,A., Collin,R.W., McLaughlin,H.M.,
            Held,S., Kasanuki,J.M., Ramaswami,G., Conte,J., Lopez,I.,
            Washburn,J., Macdonald,J., Hu,J., Yamashita,Y., Maher,E.R.,
            Guay-Woodford,L.M., Neumann,H.P., Obermuller,N., Koenekoop,R.K.,
            Bergmann,C., Bei,X., Lewis,R.A., Katsanis,N., Lopes,V.,
            Williams,D.S., Lyons,R.H., Dang,C.V., Brito,D.A., Dias,M.B.,
            Zhang,X., Cavalcoli,J.D., Nurnberg,G., Nurnberg,P., Pierce,E.A.,
            Jackson,P.K., Antignac,C., Saunier,S., Roepman,R., Dollfus,H.,
            Khanna,H. and Hildebrandt,F.
  TITLE     Candidate exome capture identifies mutation of SDCCAG8 as the cause
            of a retinal-renal ciliopathy
  JOURNAL   Nat Genet 42 (10), 840-850 (2010)
   PUBMED   20835237
REFERENCE   6  (bases 1 to 2534)
  AUTHORS   Kamio,T., Asano,A., Hosaka,Y.Z., Khalid,A.M., Yokota,S., Ohta,M.,
            Ohyama,K. and Yamano,Y.
  TITLE     Expression of the centrosomal colon cancer autoantigen gene during
            spermatogenesis in the maturing rat testis
  JOURNAL   Biosci Biotechnol Biochem 74 (7), 1466-1469 (2010)
   PUBMED   20622438
  REMARK    GeneRIF: the gene and protein expression of serologically defined
            colon cancer antigen 8
REFERENCE   7  (bases 1 to 2534)
  AUTHORS   Kenedy,A.A., Cohen,K.J., Loveys,D.A., Kato,G.J. and Dang,C.V.
  TITLE     Identification and characterization of the novel
            centrosome-associated protein CCCAP
  JOURNAL   Gene 303, 35-46 (2003)
   PUBMED   12559564
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Nov 27, 2020 this sequence version replaced NM_177929.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF352814.1, BC086973.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               JAXUCZ010000013.1  91286787-91286956
            171-323             JAXUCZ010000013.1  91296845-91296997
            324-406             JAXUCZ010000013.1  91298335-91298417
            407-520             JAXUCZ010000013.1  91301032-91301145
            521-646             JAXUCZ010000013.1  91303244-91303369
            647-787             JAXUCZ010000013.1  91309269-91309409
            788-852             JAXUCZ010000013.1  91313011-91313075
            853-1041            JAXUCZ010000013.1  91313361-91313549
            1042-1180           JAXUCZ010000013.1  91321324-91321462
            1181-1333           JAXUCZ010000013.1  91330487-91330639
            1334-1468           JAXUCZ010000013.1  91336541-91336675
            1469-1585           JAXUCZ010000013.1  91339795-91339911
            1586-1728           JAXUCZ010000013.1  91375502-91375644
            1729-1856           JAXUCZ010000013.1  91402961-91403088
            1857-1965           JAXUCZ010000013.1  91405113-91405221
            1966-2097           JAXUCZ010000013.1  91412460-91412591
            2098-2224           JAXUCZ010000013.1  91467684-91467810
            2225-2534           JAXUCZ010000013.1  91475877-91476186
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24-q25"
     gene            1..2534
                     /gene="Sdccag8"
                     /note="SHH signaling and ciliogenesis regulator SDCCAG8"
                     /db_xref="GeneID:305002"
                     /db_xref="RGD:727781"
     exon            1..170
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..2254
                     /gene="Sdccag8"
                     /note="serologically defined colon cancer antigen 8
                     homolog; slinky"
                     /codon_start=1
                     /product="serologically defined colon cancer antigen 8"
                     /protein_id="NP_808790.2"
                     /db_xref="GeneID:305002"
                     /db_xref="RGD:727781"
                     /translation="MAKSPGNSTLEDSLGQYQRSLRERANRSIHQLKCALREVDATIE
                     EDALDPSTSINVENVDTGVAWHELQHSHAVNQLKALLRQQTSTENETSPRRRKLSPSR
                     PSDCEDGSLPTMHNLVPIINDQSQYIHHLEAEVKFCKDELSSMKNRVQVVVLENERLQ
                     QELKSQRQEETLREQTLLDMSGNVQNSWMKTREDSRVIETTKRPFSHGDAETGKAAST
                     GDADKWRLELERLKLTYEAKTDLLESQLKLLRKDLVEYQKTCEDLKERLKHKESLVTA
                     SASSRVGGLCLKCAQHEAVLSQTHNNVHIQTIETLTKERDDLMSVLVSVRSSLAEAQE
                     RETSAYKQVKHAVQMTEEANFEKTKALIQCEQLRSELERQTDRLEKELASQQEKRALE
                     KEMIKKEVTREREEAEAKMLILSQNIAKLEAEIEKITREKTSAVSQLEEVQNQLASQE
                     MDVTKVCGEMRFQLNKTKMEKDEAEKEHKEYKAKSQKDLEMKDQEIEKLRLELSESTQ
                     QVEQEQQKAARARQECLQVTELLGESERQLHLTRLEKDSIQQSFSNEAKAQALQALQR
                     EQELTQKIQQMETQHDKTDSEQYLLLTSQNTFLTKLKEECCILAKKLEKVSLKSRSEI
                     VQLSQEKRYLCDKLEKLQKRNDELEDQCVQHGRVHETMKERLRQLDKHGQATAQQLVQ
                     LLNKQNQLLLERQNLSEEVDQLRAQLPSMPQSDC"
     exon            171..323
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            324..406
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            407..520
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            521..646
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            647..787
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            788..852
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1041
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1180
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1333
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1468
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1585
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1728
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1856
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..1965
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            1966..2097
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2224
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2534
                     /gene="Sdccag8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagctacag gaagcaggca ggcatccccc aacccccaac gctaggcctg tcctcggagg
       61 ggtgcactgg acactttcca tcataactcc catctctgac cccatggcga agtccccagg
      121 gaactctacc ctggaggaca gtctggggca ataccaacgg agtctccggg aacgtgccaa
      181 tagaagcatt caccaattga aatgtgccct gagagaagtc gatgccacca tagaggaaga
      241 tgcactggat ccttccacca gcattaacgt agaaaatgtg gacacagggg tggcctggca
      301 tgaactgcag cacagccatg ctgtcaatca gctgaaggct ttgttgcgac aacaaacaag
      361 tacagaaaat gagacatctc cacgaagacg aaagttgtcc ccttcgcggc cctcagattg
      421 tgaggatggt agcttgccta ccatgcacaa ccttgttcct atcattaacg accagtctca
      481 gtatattcac catttggaag cagaagtcaa gttctgcaag gatgaattat ccagcatgaa
      541 aaatagggtg caagtagttg tacttgagaa tgaaaggctc cagcaagaac tgaaatctca
      601 aagacaggag gagaccctga gggagcaaac acttctagat atgtctggaa acgtgcagaa
      661 ttcttggatg aagacacgag aagattctag ggtgattgaa actacaaaga gaccgttttc
      721 tcatggtgat gctgagactg gcaaagctgc atccaccggt gatgctgaca aatggaggct
      781 agagctggag aggctgaaac tcacatatga ggcgaagact gaccttctgg agtctcagct
      841 gaagcttttg aggaaagact tggttgaata tcagaaaacc tgtgaggatc ttaaggaaag
      901 attgaagcat aaagagtctc ttgtgaccgc gagtgcatcc agccgtgtgg gcggcctctg
      961 tttgaagtgt gctcagcatg aagctgttct ttcccagacc cacaacaacg tgcacatcca
     1021 gaccatcgag acgctgacta aagagaggga tgacttaatg tctgtgctgg tttctgtgcg
     1081 gagcagcttg gcggaagcac aggagaggga gacaagcgcc tacaagcagg tgaagcacgc
     1141 tgtgcagatg accgaagaag ccaactttga aaagaccaag gctttgatcc agtgtgagca
     1201 gctgaggagt gagctggaga ggcagacaga cagactggag aaggaacttg cctctcagca
     1261 agaaaaaagg gctctggaga aggagatgat aaagaaagaa gtaaccagag agcgggaaga
     1321 ggcggaggct aagatgttga tcctatctca gaatattgcc aagctggagg ccgagattga
     1381 aaagattaca agggagaaga cttcagctgt cagtcaatta gaggaagtgc agaaccagct
     1441 tgcatctcag gaaatggacg tcacaaaggt gtgtggagaa atgcgctttc agttgaataa
     1501 aaccaaaatg gagaaggatg aggcagaaaa ggaacacaaa gaatacaaag caaaatctca
     1561 aaaggatctt gaaatgaaag atcaggaaat agagaagttg agactggaac tgagcgaaag
     1621 cacgcagcaa gtggagcagg agcagcagaa ggcagctcgg gccagacagg agtgcctgca
     1681 agtcacagag ctgctgggcg agtctgagcg ccaactgcac ctcaccagac tggaaaaaga
     1741 tagcattcag caaagcttta gcaacgaagc aaaggcccag gccctccagg ccctgcagag
     1801 agagcaggag ctgacacaga agatacagca aatggagacc cagcacgaca aaactgacag
     1861 tgaacagtat ttactgctga cctcccagaa tacatttctg acaaagttaa aagaagaatg
     1921 ctgcatatta gccaagaaac tggagaaagt ctcactgaag agcagatcgg aaatagttca
     1981 actcagtcaa gaaaaaagat acttgtgtga taagctagag aagttacaga agagaaatga
     2041 cgaactggag gatcaatgtg tccaacatgg gagggtgcat gagacgatga aggaaaggct
     2101 caggcagctg gataagcatg gtcaggctac agcgcagcag ctggtgcagc tgcttaacaa
     2161 gcagaatcag cttctcctgg agcgacagaa cctgtcagag gaagtggacc agctgcgagc
     2221 ccagttaccc agcatgccac aatctgattg ctgacctgga tgaaacagag tgaaataaat
     2281 gatttacaaa gagatattta cattcatctg atttgtactt aatgtgcaca gtgcaccgaa
     2341 acctccccag ggagacacca gcagggactg caggggggct ggtcctcacg ccatggcctg
     2401 tccctgtgct acagacaggg agtgcttcag cgtcaactgg ctagggctag tcgggagtgt
     2461 gtgctcagaa cagcttcaag tcactgattt cccttgtctc taaagtatgc acagggatta
     2521 ataaaaagtc tttc
//
