LOCUS       NM_001191780            4745 bp    mRNA    linear   ROD 15-NOV-2024
DEFINITION  Rattus norvegicus SCY1 like pseudokinase 2 (Scyl2), transcript
            variant 2, mRNA.
ACCESSION   NM_001191780 XM_235050
VERSION     NM_001191780.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4745)
  AUTHORS   Terabayashi,T., Funato,Y., Fukuda,M. and Miki,H.
  TITLE     A coated vesicle-associated kinase of 104 kDa (CVAK104) induces
            lysosomal degradation of frizzled 5 (Fzd5)
  JOURNAL   J Biol Chem 284 (39), 26716-26724 (2009)
   PUBMED   19643732
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jul 17, 2010 this sequence version replaced XM_235050.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.9853.1,
                                           SRR26643292.28936.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               JAXUCZ010000007.1  26004400-26004631   c
            233-437             JAXUCZ010000007.1  25993416-25993620   c
            438-595             JAXUCZ010000007.1  25986115-25986272   c
            596-740             JAXUCZ010000007.1  25984230-25984374   c
            741-890             JAXUCZ010000007.1  25979595-25979744   c
            891-1112            JAXUCZ010000007.1  25978348-25978569   c
            1113-1229           JAXUCZ010000007.1  25977539-25977655   c
            1230-1355           JAXUCZ010000007.1  25976607-25976732   c
            1356-1532           JAXUCZ010000007.1  25975497-25975673   c
            1533-1655           JAXUCZ010000007.1  25972885-25973007   c
            1656-1769           JAXUCZ010000007.1  25971654-25971767   c
            1770-1902           JAXUCZ010000007.1  25968502-25968634   c
            1903-2021           JAXUCZ010000007.1  25967538-25967656   c
            2022-2122           JAXUCZ010000007.1  25964200-25964300   c
            2123-2189           JAXUCZ010000007.1  25962699-25962765   c
            2190-2285           JAXUCZ010000007.1  25962477-25962572   c
            2286-2405           JAXUCZ010000007.1  25954879-25954998   c
            2406-4745           JAXUCZ010000007.1  25951734-25954073   c
FEATURES             Location/Qualifiers
     source          1..4745
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..4745
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /note="SCY1 like pseudokinase 2"
                     /db_xref="GeneID:314717"
                     /db_xref="RGD:1305665"
     exon            1..232
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            233..437
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..3053
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /note="isoform 2 is encoded by transcript variant 2;
                     SCY1-like protein 2; SCY1-like 2; SCY1-like, kinase-like
                     2"
                     /codon_start=1
                     /product="SCY1-like protein 2 isoform 2"
                     /protein_id="NP_001178709.1"
                     /db_xref="GeneID:314717"
                     /db_xref="RGD:1305665"
                     /translation="MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNG
                     LAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLL
                     TVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQ
                     VSEGLSFLHSSVKMVHGNVTPENIILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEW
                     DPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGRPIFEVNKQDIYK
                     SFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVT
                     LQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNPDMVPFVLPN
                     VLLIAEECTKEEYIKLILPELGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVL
                     PMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNS
                     LVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQL
                     AGKVLPHLIPLSIENNLNLNQFSSFIAVIKEMLSRLESEHRTKLEQLHIMQEQQRSLD
                     IGNQMSTSEETKVTPSGTQQIDKVFNNIGADLLSGGESENREDGLQGKQKRGSLTLEE
                     KQKLAKEQEQAQKLKSQQPLKPQVHTPIAPVKQTKDLTDTLMENMSSLTSLSVSTPKI
                     SASSTFTSVPSTGLSMMFSTPIDNTKRNLTNGLNANMGFQTSGFNMPVNPNQNFFSGT
                     STAGVTTMTLGAPPTMSNFSPLSIPPASVKQTQQRPPDMSALNNLFGPQKPKVSMNQL
                     SQQKPNQWLNQFVPPQGSPGMGSAAMGTQVNVMGQAAFGMQGNPFFNPQSFAQPPPTT
                     MTSSSSASNDLKDLFG"
     exon            438..595
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            596..740
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            741..890
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1112
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1229
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1355
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1532
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1655
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..1769
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1902
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2021
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2122
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..2189
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2285
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2405
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
     exon            2406..4745
                     /gene="Scyl2"
                     /gene_synonym="RGD1305665"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggtctttc ggtgctcttc cccctaccgt gctcttcctc cctagtccct tccctccctt
       61 ccccctttac tcctcggtct cggggttctg cggcctcggg ggtggcggag gagatggagt
      121 aagcgttcgg tggcggccag gcgcgcggcc cgagcagtca cagcccggag gcattgaggg
      181 agcgggcggg ggacgggccc tagcaccgcc cctccaggta gccggctgag aggtgacttg
      241 aactaccaag tactgcagcc atggagtcca tgctcaataa actgaagagt actgttacaa
      301 aagtaacagc cgatgtcacc agcgcggtta tgggaaaccc tgtcactaga gaatttgatg
      361 ttgggcgaca cattgccagt ggtggcaatg ggttggcctg gaagattttt aatgggacaa
      421 agaagtcaac caaacaggaa gtggctgttt ttgtctttga taaaaagctg attgacaaat
      481 atcaaaaatt tgaaaaggat caaatcatcg attctttaaa acgtggagtc caacagctaa
      541 cccggctacg acaccctcga cttcttactg tccagcatcc tttagaagag tcaagggatt
      601 gcttggcatt ttgtacagaa ccagtttttg ccagtttagc caatgttctt ggtaactggg
      661 aaaatctacc ctcttcaata tctccagaca tcaaggatta taaactttat gatgtagaaa
      721 ctaagtatgg tttgcttcag gtttctgaag gattgtcatt tttgcatagc agtgtaaaaa
      781 tggttcatgg aaatgttact cctgaaaata taattttgaa taaaagtgga gcctggaaaa
      841 taatgggttt tgacttttgt gtgtcgtcga gcaatccttc tgaacaagag cccaagtttc
      901 cttgtaagga gtgggatcca aacttaccat cattgtgtct tccaaatcct gagtacttgg
      961 ctcctgagta tatcctgtcg gtgagctgtg agacagccag tgacatgtac tccttaggag
     1021 ctgttatgta tgctgtgttt aataaaggga gacctatatt tgaagtcaac aagcaggata
     1081 tttacaagag tttcagtaga caactggatc agttgagtcg tttaggatct agttcactca
     1141 caagcatacc cgaggaagtt cgtgaacatg tcaaactgtt gttaaatgta actccgactg
     1201 taagacccga tgcagatcaa atgacaaaaa ttcccttctt tgatgatgtt ggtgcagtaa
     1261 ctcttcaata ttttgatacc ttattccaaa gagataatct ccagaaatca cagttcttca
     1321 aaggattgcc aaaggttcta ccaaagctgc ccaagcgtgt cattgtgcag agaattttac
     1381 cctgtttgac ctcagaattt gtaaatcctg acatggtacc ttttgttcta ccgaatgttt
     1441 tgctgatcgc tgaggagtgc accaaagaag aatatatcaa attaattcta cctgaacttg
     1501 gtcctgtgtt caaacagcag gagccaatcc agattttgtt aatttttcta caaaaaatgg
     1561 atttgctgct aaccaaaacc cctccggatg agataaagaa cagcgtcctg ccaatggtct
     1621 acagagctct ggaggctcct tcaattcaga tccaggagct ctgtctaaac atcattccaa
     1681 cttttgcaaa tcttatagac tacccgtcca tgaaaaacgc tttgattcca agaattaaaa
     1741 atgcctgttt acaaacgtct tcccttgctg ttcgtgtgaa ctcattagtg tgtttaggga
     1801 agatcctgga gtacttggat aagtggtttg tacttgatga tatcctgccc ttcttacagc
     1861 agattccctc caaggaacct gcagtcctca tggggatttt aggtatttat aaatgtactt
     1921 ttactcataa aaagttggga atcaccaaag agcagctggc tggaaaggta ctgcctcatc
     1981 tcatccccct gagcattgaa aacaacctca acctcaacca gttcagctcc ttcattgctg
     2041 tcataaagga gatgctgagc cgactggagt ctgagcacag gactaagctg gagcagcttc
     2101 acataatgca ggagcagcag aggtctttgg acatagggaa tcaaatgagc acttctgagg
     2161 agacaaaagt cacaccttct ggaactcagc agattgataa agtctttaac aacattggtg
     2221 cagaccttct aagtggcggt gaatcagaaa atagagaaga cgggctgcag ggtaaacaga
     2281 aaagagggtc actaacactt gaagagaaac agaaattagc gaaagaacag gagcaggcac
     2341 agaagctgaa gagccagcag cctcttaagc cccaagtcca cacgcccatc gctcctgtca
     2401 aacagactaa ggacttgaca gacacattga tggagaacat gtcgtctttg accagccttt
     2461 ccgttagcac tcctaagatt tctgcttcaa gcaccttcac ctcagttccc tccacaggcc
     2521 tcagcatgat gttttctaca ccaattgata atacaaagag aaatttgaca aatggcctaa
     2581 atgccaacat gggctttcag acttcagggt tcaacatgcc agtcaatcca aaccagaact
     2641 tcttcagtgg tacgagcaca gctggtgtga ccaccatgac tctgggagca cctcctacca
     2701 tgtcaaactt cagccctttg agtattcctc ctgctagtgt gaagcagact caacagagac
     2761 cacctgatat gtctgccctt aataatctct ttggccctca gaaacccaaa gtcagcatga
     2821 accagctgtc ccaacagaaa ccaaatcagt ggctgaatca gtttgtacct cctcaaggtt
     2881 ctccaggcat gggcagtgca gccatgggca cacaggtgaa tgtgatggga caggctgcct
     2941 ttggtatgca gggcaaccct ttcttcaacc cacagagctt cgcacagcca ccaccaacta
     3001 ctatgaccag tagcagctca gctagcaatg atttgaaaga tcttttcggg tgaggtgtct
     3061 ctcgctgcct tttggagggt cactgcagtt tcaatcatgg gaaagctgac ttacgtcagt
     3121 gtgaggctgt cttgaagaaa ctgcttctgt gggagatgga ttgtttctgt gacagaaaac
     3181 tcctgcttcc atgccagcca gcgtaggagt tgtgtgcatc ctaacaagtg gaagctttta
     3241 aagcatggag gattttctcc ctattacaaa ctcctcttca ggtttttaaa gatccagtcc
     3301 ttactagtct caaagtgcaa aaggacagct gaattatcct gaatagcagt ttttaaatca
     3361 gatgttttat tttggcttgt aaatcttctt gttattaaaa accttgagtt gatggtaact
     3421 ggaagtcccc ttggtatcta ccttcatatt cacttgtctt cattgaaagg gaagagtctt
     3481 gatgctgtgc taatgtgtgt gcatttgtaa gatagtgggc gacaacacag aaaggattgg
     3541 gtcattattc gcttttctag tcttattttt caaagaaatg tatgcttaat aaaagcacag
     3601 caaaatgctg caaaatttaa cttatattaa tttcattggt ttaaaaaaca ttaaccattc
     3661 taaatgcaaa ctaatcattg taagttatat tttagcatga tctgcctcaa atagcaatgt
     3721 atttttctgc ctttacttga atatatttag gctcactttc ttccctgttg tatcacagag
     3781 gagctatgta ccgatttgta cagaaaacag acagagcact cggacacgat tttctcaact
     3841 actgccttca tacttgattt tcagttcaaa cttctgagga tgcggcatat atgaattaca
     3901 ttttcgaaag gagatttgtt aaaaatttag ttaagctata tttaatgagt aacttttgag
     3961 atttctgcca tattgtttca atatagtaaa gtctaaaaat gagcaagcca ttggctacca
     4021 tcaggttcga tgttagcttg ccgtgatgcc tgacctcgct agttactact acagttgaat
     4081 tcttttctag acgtcccaga aactttgttt ggacatttag tgtctgtaat cagccactgt
     4141 taggaaggaa ggagtcaatt ctaataggcc acacctcact ttttggaacc gttctgatgt
     4201 ctgtcgttaa cttgctgatt ctaccacaga gccttatgct atagacgtca tttgtatttt
     4261 taaaaagtat actccactgt tatgtgataa ttataaaact cctaaaaaaa ctctgtatgt
     4321 attatagttg ctgccataca gtttgtggtt tttaattatc tggaaccagc aatccttaaa
     4381 taaatcatat gaagtttatt aaatggctga atgttcattc agattatata cgtgtgtgca
     4441 catggtgggt ataaattgta ggacttgatt acaaagtaca tttcatgctg ataccaatgc
     4501 tgaaagcatc cagttaaagc acacttgtaa aaaacgtgag tcagcagtca cacctcactc
     4561 ctgagtgtac tacacttggg tggcatgact taaaaaggac tggaggatgc aaagaagtca
     4621 ctcaaaaatt aaaagccgtt tatcttcgca actttgcctg attcattttt aacacgatac
     4681 taatatttct tttgggaaat gttttatatg gaataaaatt gttattgaag aatatttctt
     4741 tggaa
//
