LOCUS       XM_039105648            6743 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus sodium voltage-gated channel alpha
            subunit 3 (Scn3a), transcript variant X10, mRNA.
ACCESSION   XM_039105648
VERSION     XM_039105648.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039105648.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6743
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6743
                     /gene="Scn3a"
                     /gene_synonym="Nav1.3; SCIII; Scn2a"
                     /note="sodium voltage-gated channel alpha subunit 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 16 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     12 samples with support for all annotated introns"
                     /db_xref="GeneID:497770"
                     /db_xref="RGD:3635"
     CDS             312..3659
                     /gene="Scn3a"
                     /gene_synonym="Nav1.3; SCIII; Scn2a"
                     /codon_start=1
                     /product="sodium channel protein type 3 subunit alpha
                     isoform X7"
                     /protein_id="XP_038961576.1"
                     /db_xref="GeneID:497770"
                     /db_xref="RGD:3635"
                     /translation="MAQALLVPPGPESFRLFTRESLAAIEKRAAEEKAKKPKKEQDID
                     DENKPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYVSKKTFVVLNKGKAIFRF
                     SATSALYILTPLNPVRKIAIKILVHSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYT
                     FTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTF
                     RVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNK
                     CLQWPPSDSAFETNTTSYFNGTMDSNGTFVNVTMSTFNWKDYIADDSHFYVLDGQKDP
                     LLCGNGSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDYWENLYQLT
                     LRAAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLE
                     QLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKSAKEWRNRRKKRRQ
                     REHLEGNHRADGDRFPKSESEDSVKRRSFLLSLDGNPLTGDKKLCSPHQSLLSIRGSL
                     FSPRRNSKTSIFSFRGRAKDVGSENDFADDEHSTFEDSESRRDSLFVPHRPGERRNSN
                     VSQASMSSRMVPGLPANGKMHSTVDCNGVVSLGTTTETEVRKRRLSSYQISMEMLEDS
                     SGRQRAMSIASILTNTMEELEESRQKCPPCWYRFANVFLIWDCCDAWLKVKHLVNLIV
                     MDPFVDLAITICIVLNTLFMAMEHYPMTQQFSSVLTVGNLVFTGIFTAEMVLKIIAMD
                     PYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIK
                     IIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINVDCKLPRWHMNDFFH
                     SFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVFMLVMVIGNLVVLNLFLALLLSSFSS
                     DNLAATDDDNEMNNLQIAVGRMQKGIDFVKNKIRECFRKAFFRKPKVIEIQEGNKIDS
                     CMSNNTGIEISKELNYLKDGNGTTSGVGTGSSVEKYVIDENDYMSFINNPSLTVTVPI
                     AVGESDFENLNTEEFSSESELEESKEG"
ORIGIN      
        1 ttcccttcca gggccgtttt ctgatatatg ttgggtacca tagagtgaat ctcagaacag
       61 gaagcggagg cataagcaga gaggattctg gaaaggtctc tttgttttca tgtccacaga
      121 gaaagcaagg gggaaaaatt gaatgtaatt tgcaaatccc tgtggcccaa atctgaagaa
      181 ctacaggggg tggcaccgtc cattctaacc atcttggatg ctgtcctttg ttgagctgtg
      241 attcctaagg ctctccatca ggcaattctt atgcaagaag ctaaacgtaa ttaaatgtgc
      301 aggatgaaaa gatggcccag gcactgctgg tacccccggg acctgagagc ttccgccttt
      361 tcactcgaga atctcttgct gctatcgaaa agcgtgctgc agaagagaaa gccaagaaac
      421 ccaagaaaga gcaagacatt gacgatgaga acaaaccaaa gccaaacagc gacttggaag
      481 ctgggaagaa ccttccattt atctatggag acattcctcc agagatggtg tcggagcccc
      541 tggaggacct ggacccctac tatgtcagta agaaaacttt tgtagtgttg aataaaggga
      601 aggcgatttt tcgattcagc gccacctccg ccctgtatat tttaactccg ctaaaccctg
      661 ttaggaaaat tgccattaag attttggtac actctttgtt cagcatgctt atcatgtgca
      721 ctattttgac caactgtgta tttatgacgt tgagtaatcc tcccgactgg acaaagaatg
      781 tagagtatac gttcactggg atctatacct ttgagtcact tataaagatc ttggcaagag
      841 ggttttgctt agaagatttc actttcctcc gtgacccatg gaactggctg gatttcagtg
      901 tcatcgtgat ggcatatgtg acagagtttg tggacctggg caatgtctca gcgctgagaa
      961 cgttcagagt tctccgagca ttgaaaacaa tatcagtcat tccaggttta aagaccatcg
     1021 tgggggccct gatccagtcc gtgaagaagc tgtccgacgt catgatcctc accgtgttct
     1081 gtctcagtgt ctttgctcta atcgggctgc agctcttcat gggcaacctg aggaataaat
     1141 gcttgcagtg gcccccgagc gattcggctt ttgaaaccaa cactacttcc tacttcaatg
     1201 gcacaatgga ttcaaatggg acatttgtta atgtaacaat gagcactttc aactggaagg
     1261 attatatcgc agatgacagt cacttttatg tcttggatgg acaaaaagat cctttactct
     1321 gtggaaatgg ctccgatgca ggacaatgtc cagaagggta catctgtgtg aaggctggac
     1381 gaaaccccaa ctacggctac acaagctttg acaccttcag ctgggccttc ttgtccctgt
     1441 ttcgactcat gactcaggac tactgggaga atctttacca gttgacattg cgtgcagctg
     1501 ggaaaaccta catgatattt ttcgtcctgg taattttctt gggctcgttt tatttggtga
     1561 acttgatcct ggctgtggtg gccatggcct atgaggagca gaaccaggcc acactggagg
     1621 aggctgaaca gaaggaggca gagtttcagc agatgctgga gcaactgaag aagcagcagg
     1681 aggaggctca ggcagtggct gcagcctccg cggcatccag agacttcagt ggaataggag
     1741 ggttaggaga acttctggag agttcttcag aagcttccaa gttgagctcc aagagtgcta
     1801 aggagtggag gaaccggagg aagaagagga gacagaggga acacttggag ggaaaccaca
     1861 gagccgatgg agacaggttt cccaagtcgg aatcggaaga cagtgtcaaa cgaagaagct
     1921 tcctgctctc cctggatggc aacccgctga ctggtgacaa gaagctgtgc tctccccacc
     1981 agtctctctt gagtatccgt ggctccctgt tttccccaag acgcaatagc aaaacgagca
     2041 ttttcagctt cagaggtcgg gcgaaggacg tggggtctga gaatgacttt gcagacgatg
     2101 agcacagcac cttcgaggac agcgagagca ggagagactc cctgtttgtg ccgcacagac
     2161 ctggagagcg acgcaacagt aacgttagtc aggccagtat gtcatccagg atggtgccag
     2221 ggcttccagc aaatgggaag atgcacagca ctgtggattg caatggtgtg gtttccttgg
     2281 gtaccaccac tgaaacggaa gtcaggaaga gaaggctaag ttcttaccag atttcgatgg
     2341 aaatgctgga ggattcctct ggaagacaaa gagccatgag catagccagt atcctgacca
     2401 acaccatgga ggaacttgaa gaatctagac agaagtgccc accatgctgg tatagattcg
     2461 ccaatgtgtt tttgatctgg gactgctgtg atgcatggtt aaaagtgaag catcttgtga
     2521 atttaattgt gatggatcca tttgttgatc ttgccataac aatttgcatc gtattaaata
     2581 cactgttcat ggccatggag cactatccca tgacccagca gttcagcagt gtgctgactg
     2641 tgggaaacct ggtcttcact gggatcttca cagccgaaat ggtccttaaa atcattgcca
     2701 tggaccccta ttattatttc caagagggct ggaatatttt cgatggaatt attgttagcc
     2761 tgagtttaat ggagctaggc ctggcaaatg tggaggggct gtctgtgctt cggtccttca
     2821 gactgctccg agtcttcaag ttggcaaagt cctggcccac actgaacatg ctcattaaga
     2881 tcatcggcaa ctcggtgggc gcactgggca acctgaccct ggtgctggcc atcatcgtct
     2941 tcatttttgc cgtggtcggc atgcagctgt ttggaaagag ctacaaggag tgtgtctgca
     3001 agatcaatgt ggactgcaag ctgccgcgct ggcacatgaa cgacttcttc cactccttcc
     3061 tgatcgtgtt ccgagtgctg tgtggggagt ggatagagac catgtgggac tgcatggagg
     3121 tcgcgggcca gaccatgtgc cttattgtgt tcatgttggt catggtgatt gggaaccttg
     3181 tggttctgaa cctctttctg gccttattgt tgagttcctt tagttcagat aaccttgctg
     3241 ctactgacga tgataacgaa atgaacaacc tccagatcgc ggtgggaagg atgcaaaagg
     3301 gaattgattt tgtgaaaaat aagatacggg agtgcttccg aaaagcgttt ttcagaaagc
     3361 cgaaagtgat agaaatccaa gaaggcaaca aaatagacag ctgcatgtcc aataacacgg
     3421 gcatcgaaat aagcaaagag cttaactacc ttaaagacgg taatggaacc accagcggcg
     3481 tgggaaccgg aagcagtgtg gaaaaatacg taatcgatga aaatgactac atgtcattca
     3541 taaacaatcc cagcctcacc gtgactgtgc caattgctgt gggagagtct gactttgaaa
     3601 atttaaatac ggaagagttc agcagtgagt cagaattgga agaaagtaag gaggggtgag
     3661 accaagctgg agccatcaag aaagccgctc tggtgttttt taagcagcca gaggctcgag
     3721 ccaccacttt tacccaggtt acccatgcaa gttgtcactt cctagatgaa ttttgactgg
     3781 cctgcatgtt ccgcagctat attccttccc ctgccgtggc aaggaagtgc gaggctggcc
     3841 cagctgctct ctgctgaagt gtgtgataca tcacggcatg gtcaggcgag acgggcagtc
     3901 ccaacaccat atttgattct tctgatgggc tttccacgtt agtcttttag gtctcaaaaa
     3961 ttgcatgccc gataagattt accacaatat caattttaaa catactagaa atgcttacaa
     4021 ttggatataa tcaaagactt aagcgagcat gcatattttt aatttgtttt tatttcatta
     4081 aaataagatc atagcttttt ttttgttgtt attgatgatt cagcccttat atgtaaactg
     4141 tgccaccaaa ataagcctca aggggtttgt gtgtgtgtac ctgtgtgtgt gtgtgtgtgt
     4201 gtgagagaga gagagagaga gagagagaga gagagacaga cagacagaca gacagacaga
     4261 gacaaagaga gagaggatgt gttcatgtgt gtgtgcgtgc atgcatgtgt ttgtaggtct
     4321 gtaagtactg ccattttcaa gtcattatat tcagatcaat gaatatcact ttcaactgaa
     4381 ccaattcctg tgctccatat ggaaatatat gctttcatgc attcagaaag gctctgtaaa
     4441 aaacaatagg agaatcttga gatcttaaag aagccaggta ttagtctgaa tatgcgtttg
     4501 ggcactaggt gtcttggact ttgaagagtt tggaaaattt tcagtcaagc gcctgaaaaa
     4561 acacagtgat catcataaag tagtccaaag tgagactcca tgctgtaagc atgcgacatg
     4621 ggacacacat gtcaccaaat cattgctcta aagtacttgt ttgggagttt cgtttgattt
     4681 taagtatttg acttggtatt tccctctgtg cattaatttc tcccctaaat gttctacctc
     4741 agactgagta tgcaaaaatg gcacttggaa cattttctgg ttctgacggt tggctatagt
     4801 tttatgagga gtagagtcat cttctgcaag tgctgtggta gtctgtctta gctgagttgt
     4861 gactctatgg acttaattgt ctgctgttgg tgtcattact tactgatttc aaagtgcaag
     4921 gtttaggggg gaaattaacc agaaatcaaa cattgctaca tgttggatat ttgctggact
     4981 aaaatctact tttaatttag atttgtctgt gagttttatt gatacatgca ttcttctgta
     5041 ggagcattga gacttaattg ttgagttcaa ccaactcaaa aatacttttt agtgaaaggc
     5101 ggaaaaaata ctcttgctgt tgatttagct gaatagaatg aaatagtgtt ggatagttgt
     5161 aggtctcatc atgttcctct caggggaact cgtttctgga gcttttgtgg aagttttaaa
     5221 cagtaggtgt ttgactgagt tcttaagccc acaactgact agaaaaagga ctgtgttttt
     5281 ttcggactct gatgaaggat ggggaagtga ctttagcttt tgatttctcg actgtgtctt
     5341 tcaaataact tttcaggagg cagagatggt atgtaaatag ccactctgac ccatctcaac
     5401 ctgtagagaa ctgtttcggt gttcttctgc agagaaaacc cccattaagt ctggttttga
     5461 tggaaatgtt tgtctccctt ctcaagataa gtggcctttc tctcctgctt tcctaatgcc
     5521 ctttgcctca ctcttcaact acgacataat taccttccat tttccatacc atgcttttat
     5581 gaacatggct atttttacat aaaaggagca ctcagggtat tatacattta acatatgtca
     5641 aggaggagcc agatggtggc agtttatatt ttttaaccac tcagtaagtg gttgaaaaga
     5701 acgttattgg ctttagtcac gtctttttgc cttggacaag caacaaatgg ccccagtaga
     5761 tggctacttg ttgttcaccc aaaatgtttt aaagcaggat atgaattttc atatccaagt
     5821 tgtcagaccg aggtcctcaa aagactttct ttgtctacct gtatgataaa atcgaggatt
     5881 ccttgagagt aatgtctcga tttttgaggc aatctgtaat ggctgaatct tttactttgt
     5941 ctcttgaacc atatagcagt ttgtaagagt caaaaaaaaa atgtgagcgc tgattgaaaa
     6001 aaaaaataat gaatgaaatg tgagcgcatt tcagtggaag taggccagtt gctaacattc
     6061 tcttctacct ctgaaagtta aattttatta tttaattgga caaaatacca agagcgctat
     6121 tcttcacgct cttcctctag agaggacgtt ctctataagg tcacgtgatc tggggggaat
     6181 gtcctcgtgg cctgtttggt tgctaattct gtcattcctc tgtggtgata agccattcct
     6241 ctgagtgagt ggtagttgta gttgaccttg aaagcatcgt aatcaggtac catgtttgag
     6301 agcatggttc ttggatcagc aagcgcttcc acagcattgc gccaggcttc tgctgtagcc
     6361 aggcatgttt tctatggctg agttcggcct ggagaatgtt gcatcttaaa tcctgcttcc
     6421 ggcgtgcatc catagagcat aagccatcat ccttctgtag attcagcagt ctctacaagg
     6481 gatggaagtc tctaactttt aagggccatg taatattgga caggttaagg agaaaatagt
     6541 acaagggacc aagactgaac ttgtactatg tggtcttatc tggaagcctt cagcggttat
     6601 gcctatattc ccagatatgt ttgtttgttc taactttctc ggaacttagt gtatttatgt
     6661 aatttaatat ggtaaatttc atttctggtt tctttgctct tttgatatca ttgtagtatc
     6721 acaactctgg caatataaat gaa
//
