LOCUS       NM_203333               1118 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus secretoglobin, family 2A, member 1 (Scgb2a1),
            mRNA.
ACCESSION   NM_203333 NM_001375404 XM_342018
VERSION     NM_203333.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (bases 1 to 1118)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   3  (bases 1 to 1118)
  AUTHORS   Fornander,L., Ghafouri,B., Kihlstrom,E., Akerlind,B., Schon,T.,
            Tagesson,C. and Lindahl,M.
  TITLE     Innate immunity proteins and a new truncated form of SPLUNC1 in
            nasopharyngeal aspirates from infants with respiratory syncytial
            virus infection
  JOURNAL   Proteomics Clin Appl 5 (9-10), 513-522 (2011)
   PUBMED   21805676
REFERENCE   4  (bases 1 to 1118)
  AUTHORS   Stoeckelhuber,M., Messmer,E.M., Schmidt,C., Xiao,F., Schubert,C.
            and Klug,J.
  TITLE     Immunohistochemical analysis of secretoglobin SCGB 2A1 expression
            in human ocular glands and tissues
  JOURNAL   Histochem Cell Biol 126 (1), 103-109 (2006)
   PUBMED   16395610
REFERENCE   5  (bases 1 to 1118)
  AUTHORS   Xiao,F., Mirwald,A., Papaioannou,M., Baniahmad,A. and Klug,J.
  TITLE     Secretoglobin 2A1 is under selective androgen control mediated by a
            peculiar binding site for Sp family transcription factors
  JOURNAL   Mol Endocrinol 19 (12), 2964-2978 (2005)
   PUBMED   16020486
REFERENCE   6  (bases 1 to 1118)
  AUTHORS   Tan,J., Marschke,K.B., Ho,K.C., Perry,S.T., Wilson,E.M. and
            French,F.S.
  TITLE     Response elements of the androgen-regulated C3 gene
  JOURNAL   J Biol Chem 267 (11), 7958 (1992)
   PUBMED   1339454
  REMARK    Correction to:[J Biol Chem. 1992 Mar 5;267(7):4456-66.. PMID:
            1537831]
REFERENCE   7  (bases 1 to 1118)
  AUTHORS   Tan,J.A., Marschke,K.B., Ho,K.C., Perry,S.T., Wilson,E.M. and
            French,F.S.
  TITLE     Response elements of the androgen-regulated C3 gene
  JOURNAL   J Biol Chem 267 (7), 4456-4466 (1992)
   PUBMED   1537831
  REMARK    Erratum:[J Biol Chem. 1992 Apr 15;267(11):7958.. PMID: 1339454]
REFERENCE   8  (bases 1 to 1118)
  AUTHORS   Claessens,F., Rushmere,N.K., Davies,P., Celis,L., Peeters,B. and
            Rombauts,W.A.
  TITLE     Sequence-specific binding of androgen-receptor complexes to
            prostatic binding protein genes
  JOURNAL   Mol Cell Endocrinol 74 (3), 203-212 (1990)
   PUBMED   2095354
REFERENCE   9  (bases 1 to 1118)
  AUTHORS   Claessens,F., Celis,L., Peeters,B., Heyns,W., Verhoeven,G. and
            Rombauts,W.
  TITLE     Functional characterization of an androgen response element in the
            first intron of the C3(1) gene of prostatic binding protein
  JOURNAL   Biochem Biophys Res Commun 164 (2), 833-840 (1989)
   PUBMED   2818590
REFERENCE   10 (bases 1 to 1118)
  AUTHORS   Allison,J., Zhang,Y.L. and Parker,M.G.
  TITLE     Tissue-specific and hormonal regulation of the gene for rat
            prostatic steroid-binding protein in transgenic mice
  JOURNAL   Mol Cell Biol 9 (5), 2254-2257 (1989)
   PUBMED   2747651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB791758.1, BC062401.1 and JAXUCZ010000001.1.
            
            On or before Jun 9, 2021 this sequence version replaced
            NM_001375404.1, NM_203333.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062401.1, CA338725.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN17050746 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                CB791758.1         13-87
            76-862              BC062401.1         36-822
            863-917             BC062401.1         824-878
            918-919             JAXUCZ010000001.1  215925914-215925915
            920-1118            BC062401.1         881-1079
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1118
                     /gene="Scgb2a1"
                     /gene_synonym="C3.1; Psbp1; Psbpc3; Scgb2a2"
                     /note="secretoglobin, family 2A, member 1"
                     /db_xref="GeneID:361725"
                     /db_xref="RGD:735031"
     exon            1..137
                     /gene="Scgb2a1"
                     /gene_synonym="C3.1; Psbp1; Psbpc3; Scgb2a2"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..367
                     /gene="Scgb2a1"
                     /gene_synonym="C3.1; Psbp1; Psbpc3; Scgb2a2"
                     /note="prostatein C3 subunit; prostatein peptide C3;
                     prostatic steroid-binding protein C3; secretoglobin,
                     family 2A, member 2; androgen receptor DNA-binding domain
                     DNA; prostatic steroid-binding protein 1; prostatic
                     steroid-binding protein C3.2"
                     /codon_start=1
                     /product="secretoglobin family 2A member 2 precursor"
                     /protein_id="NP_976078.1"
                     /db_xref="GeneID:361725"
                     /db_xref="RGD:735031"
                     /translation="MKLVFLFLLVTIPICCYASGSGCSILDEVIRGTINSTVTLHDYM
                     KLVKPYVQDHFTEKAVKQFKQCFLDQTDKTLENVGVMMEAIFNSESCQQPS"
     exon            138..325
                     /gene="Scgb2a1"
                     /gene_synonym="C3.1; Psbp1; Psbpc3; Scgb2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            326..1118
                     /gene="Scgb2a1"
                     /gene_synonym="C3.1; Psbp1; Psbpc3; Scgb2a2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaacactg aggtctcagc tccagagttt cctgatttct gtcttggaca acagaacaac
       61 ccacagggac tgcctcaaca tgaagctggt gtttctattc ttgttggtca ccatccccat
      121 ttgctgctat gccagtggtt ctggctgcag tattctagat gaagttatta gaggtacaat
      181 taactcaact gtgactttac atgactatat gaaattagtt aagccatatg tacaagatca
      241 ttttactgaa aaggctgtga agcaattcaa gcagtgtttt ctagatcaga ccgacaagac
      301 tctggaaaat gttggcgtga tgatggaggc aatatttaac agtgaaagct gtcaacagcc
      361 atcctaaaca tctacaagat ctttggctca caggactcca ggaaactggc aatggccaag
      421 caactgataa cacagatcat aactcttctt tcttgacccc tttttctacc tataaagtgc
      481 aagacgattg ttgaaacctc acatttatgt ctttccattt tattaaatta tctgcataca
      541 attctctctc gtgttgtttc ataaaaaata acctaagtgg gctgctctgt ctcacacttg
      601 gagttttaca cacacatatg cacatgccat acacacagag gtagacatta ggaaatgccc
      661 aggtgtggaa gtgaagaaga aaagcagctt cctcaaccct tgtgagtctc tgctatgaag
      721 aagcccccca gctgctctct tctcatcatt ctgcacacac tgcacatagc cctcctgaga
      781 ccctggggct gggatgttgg gaggttggat aacactcctg ctaccaccac tcttttccta
      841 tcttatcctc taaccccccc ccaacacttc gttttctaaa atcttgataa cccatgtgca
      901 catgagtact gggccatgga aatagatttc ctccttctgt tccctgtacg gtgctaggat
      961 actctgcagt aggaactgag gatgcctgaa tttgaacaaa acaatatata cctacttaaa
     1021 ctcttgtgtt taggctccac gtctgacaca tacatggctt ggaaaaatat tgtatctcat
     1081 gaaatgccag gagactctgg attaaaccat tttttttc
//
