LOCUS       NM_139094               4794 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus SR-related CTD-associated factor 8 (Scaf8), mRNA.
ACCESSION   NM_139094
VERSION     NM_139094.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4794)
  AUTHORS   Gregersen LH, Mitter R, Ugalde AP, Nojima T, Proudfoot NJ, Agami R,
            Stewart A and Svejstrup JQ.
  TITLE     SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
  JOURNAL   Cell 177 (7), 1797-1813 (2019)
   PUBMED   31104839
REFERENCE   2  (bases 1 to 4794)
  AUTHORS   Becker R, Loll B and Meinhart A.
  TITLE     Snapshots of the RNA processing factor SCAF8 bound to different
            phosphorylated forms of the carboxyl-terminal domain of RNA
            polymerase II
  JOURNAL   J Biol Chem 283 (33), 22659-22669 (2008)
   PUBMED   18550522
REFERENCE   3  (bases 1 to 4794)
  AUTHORS   Patturajan M, Wei X, Berezney R and Corden JL.
  TITLE     A nuclear matrix protein interacts with the phosphorylated
            C-terminal domain of RNA polymerase II
  JOURNAL   Mol Cell Biol 18 (4), 2406-2415 (1998)
   PUBMED   9528809
REFERENCE   4  (bases 1 to 4794)
  AUTHORS   Yuryev A, Patturajan M, Litingtung Y, Joshi RV, Gentile C, Gebara M
            and Corden JL.
  TITLE     The C-terminal domain of the largest subunit of RNA polymerase II
            interacts with a novel set of serine/arginine-rich proteins
  JOURNAL   Proc Natl Acad Sci U S A 93 (14), 6975-6980 (1996)
   PUBMED   8692929
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U49055.1.
            
            [WARNING] On Mar 21, 2024 this sequence was replaced by
            NM_139094.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U49055.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4794
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..4794
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /note="SR-related CTD-associated factor 8"
                     /db_xref="GeneID:245926"
                     /db_xref="RGD:708362"
     exon            1..352
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..4129
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /note="putative RNA-binding protein 16; protein SCAF8;
                     RNA-binding motif protein 16; SR-like CTD-associated
                     factor 8; CTD-binding SR-like protein rA8"
                     /codon_start=1
                     /product="SR-related and CTD-associated factor 8"
                     /protein_id="NP_620794.1"
                     /db_xref="GeneID:245926"
                     /db_xref="RGD:708362"
                     /translation="MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVV
                     QSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQVGQEKDVCAPRFSNNIISTFQNLYRC
                     PGDDKSKIVRVLNLWQKNNVFKSEIIQPLLDMAAGIPPPVVTPVLASTTVAMSNTPGT
                     PVTPVTPANVVQGLPDPWVSQITNTDTLAAVAQILQSPQGQQLQQLIQTLQIQQQKPQ
                     PSILQALDAGLVVQLQALTAQLTAAAAAANTLTPLDQGVSFNKKLMDRFDFGEDSEHS
                     EESKKEIPTPQLSHVSESVNNSIFHQIAEQLQQQNLEQLRQQLLEQQQPQKVTPQDSQ
                     EGAFGSEHSASPSQGSSQQHFLEPEANLDDSIDIQQQDMDIDEGQDVVEEEIFEPEAK
                     KVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSRSRERKRKSSRSYSSER
                     RAREREKERQKKGLPPVRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINM
                     IPPRGCAYVCMVHRQDSFRALQKLSSGSYKIGSKVIKIAWALNKGVKTEYKQFWDVDL
                     GVTYIPWEKVKVDDLDGFAEGGMIDQETVNAEWETVKTSEPVKETVQTTQSPAAVEKE
                     TVVTTQSEVFPPPVTMLQIPVAPTVPAVSLVPPAFPVSMPVPPPGFSPIPPPPFLRAS
                     FNPSQPPPGFMPPPVPPPVVPPPAIPPVVPTSLVQPPLSMTPETVKDVGFGSLVLPGG
                     SVAGNLAPSTLPAGNVFNPPSKAEPEEKVPHLTEHQIPSGENTRPVIPSDIPSSAPML
                     AQPPGASNTSGILCVQRPNVSSNSEILGVRPANVSNSAAIMGAQPPNMLNNSGILGIQ
                     PPNVSSGSGLLGVLPPNLPNNSGLVGLQPPNVTNPAGLLGTQPPIGPQNLPPLTIPAQ
                     RMPALPMLDIRPGLIAQAPGPRFPLLQPGIPPQRGIPPPSVLDAALHPPPRGPFPPGD
                     LFSQPERPFLAPGRPNIDSVPNPDKRIPLGNDNIQQEGDRDYRFPPIETREGINRPPP
                     VDVRDVVGRPIDPREGPGRPPLDGRDHFGRPPVDMRETLVRPGLDHLGRRDHFGFPPE
                     KPWGPRDFDEREHRVLPVFGGPKGLHEERGRFRAGNYRFDPRSGPWNRGFGQEVHRDF
                     DDRRRPWERQRDRDDRDFDFCREINGNRLGRDRIQNTWVPPPHARVFDYFEGATSQRK
                     GENVPQVNGGNTERHAPPPPLPVQKDPELYEKLASSGDADKEESGTAAGVESEAVVES
                     TETEGT"
     exon            353..436
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            437..481
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            482..643
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            644..797
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            798..928
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1105
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1185
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1303
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1435
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1548
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1742
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1843
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1844..1957
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2114
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2248
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2393
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..2462
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2678
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..4776
                     /gene="Scaf8"
                     /gene_synonym="Rbm16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgtgggag gaagaggaag gaggagaagg gggtggagag tggagggggc cgaagcttga
       61 gtgtggagtc cgcttccgag cggggcggag aaacagagaa ggcgccgcgc cagcccctcc
      121 cccaccaccg acccgccccg acggcctcgg tcctgctcgc tgcgcccgcc ccgcgaccat
      181 gccgggacct cacgggcgct gaggagcgtc tccagctagc cgtgctccgc ggccttctgg
      241 gcccgtcgcc cgcccttccg cacgcaacgc gcccagccgc cgcctcttcc ttcgccgggc
      301 cccgggcctc tgcgcagaca acatggaggc cgtgaagacc ttcaacagcg agttgtattc
      361 gctgaatgac tataagccac ccatttctaa agcaaaaatg acccagatta caaaggcagc
      421 catcaaagct attaagttct ataaacatgt ggtacagagc gttgagaaat tcattcagaa
      481 atgtaaacca gaatacaagg tacccggact gtatgttatt gactccattg tgcgacaatc
      541 ccggcatcag gttggtcaag aaaaggatgt gtgtgcaccc agatttagta ataacatcat
      601 tagcactttc cagaatttat atcggtgccc gggggatgac aagagtaaaa tagtgagagt
      661 attaaactta tggcagaaga ataatgtttt taagagcgag attatccagc ctctcctgga
      721 tatggcggca gggattcctc ccccagttgt caccccggtt ttggccagca ccactgtagc
      781 catgagcaac actccaggaa cacctgtgac acctgttact ccagccaatg tggttcaagg
      841 cctacctgat ccatgggtat cgcagataac aaacacagac acactggcag ctgttgccca
      901 gatcctacaa agtcctcaag gtcaacagct tcagcaacta atacagacct tacagataca
      961 acagcagaag ccccagccct ctatccttca ggctttggat gctggccttg tggttcagtt
     1021 gcaggcactc actgcacagc ttacagctgc agctgctgca gccaacacac ttactccctt
     1081 ggaccaggga gtctctttca acaagaagtt gatggataga tttgattttg gggaagattc
     1141 tgagcatagt gaagaatcca aaaaggaaat tcctactcct caactctctc acgtttctga
     1201 gtctgtgaac aactccatct tccatcagat agcagaacag ctgcagcagc agaacctgga
     1261 gcagttgcgg cagcagctcc tggagcagca gcagcctcag aaggtaactc ctcaggacag
     1321 ccaggaggga gcatttggct ctgagcactc agcttcaccc tcacaaggga gtagccaaca
     1381 gcattttctg gaacctgaag caaatttaga tgattccata gacattcagc aacaggatat
     1441 ggatattgat gaagggcaag atgttgttga agaggagatc tttgaaccag aagctaagaa
     1501 agtagctgtt cgctcaagat caagaactca ttcacgatct cgatcaaggt caccaagaaa
     1561 acggaggtcc aggtcacgct ctgggtcccg aaagcgaaag cataggaaga ggtctcgctc
     1621 ccgctccaga gagagaaaga gaaaatcctc acgttcctat tcaagtgaac gcagagccag
     1681 ggaaagggag aaagaacgcc aaaaaaaggg cttgcctcct gtcagatcga aaacgctaag
     1741 tgtatgcagc actactctct gggttggcca agtggacaag aaggctacac agcaagattt
     1801 aaccaacctt tttgaggagt ttgggcaaat cgaatccatt aatatgattc cacccagggg
     1861 ctgtgcatat gtctgtatgg ttcatcgaca agattcattt cgggctctcc agaaactgag
     1921 ttcaggatcc tataaaattg gttccaaggt cattaagatt gcctgggctt tgaacaaagg
     1981 tgtaaagaca gaatacaaac agttctggga cgtggatctt ggagtcacat atataccctg
     2041 ggaaaaagtt aaagtagatg acttggatgg ctttgcagag ggaggcatga ttgatcagga
     2101 aactgtaaat gctgaatggg aaactgtgaa aacctcagaa cccgttaaag agactgtcca
     2161 gacgacacag agtccagctg cagttgagaa ggagacagtg gtcacaacgc agtcagaggt
     2221 tttccctcct cctgtcacca tgctgcagat tcctgtagca ccaaccgttc ctgcagttag
     2281 cttagttcca ccagcgtttc ctgtgtcgat gcctgtcccc cctcctggat tcagccccat
     2341 ccctccacct ccttttctac gagcaagttt taacccttca caaccacctc ctggttttat
     2401 gccacctcca gttcccccac ctgtggtacc tccccctgca atcccacccg tagtaccaac
     2461 atctttagtg caaccaccat tgtctatgac cccagaaact gtgaaagatg ttggatttgg
     2521 cagccttgtt ttaccaggtg gttctgttgc tggcaatctt gctccttcaa ctctaccagc
     2581 tggaaatgtt tttaatcctc ccagtaaagc agagcctgaa gaaaaagtac ctcaccttac
     2641 agaacaccag attccttctg gtgagaatac cagaccagtg attccaagtg atattccaag
     2701 cagtgctcca atgttagcac agccgcctgg ggcctcaaac acctctggga tcctgtgcgt
     2761 gcagagacca aacgtatcaa gcaattctga aattctgggg gttcgtccag ccaatgtttc
     2821 caacagtgct gcgattatgg gagcccagcc accaaatatg ctcaataact ctggaatttt
     2881 gggcatacag ccaccaaatg tgtccagtgg ctctggactt cttggggtac tgcctccaaa
     2941 cttgcctaac aactctggac ttgtaggact acagccacca aatgttacaa atcctgctgg
     3001 acttttggga acacagccac caattggacc tcaaaactta ccccctttaa ccatccctgc
     3061 tcaaaggatg cctgcgttgc caatgttaga cattcgtccg ggactgatag cacaggctcc
     3121 tgggccaaga ttccctttac tacagcctgg aattccacca caacggggta tccctccccc
     3181 atcggtactt gacgcagctc ttcatccacc accccgtgga ccttttcctc caggggatct
     3241 ttttagtcag ccagaaagac cttttctggc tcctggaaga ccaaatatag acagtgttcc
     3301 taacccagat aaaagaatac cacttgggaa tgacaatatc cagcaggaag gggatagaga
     3361 ttaccgcttt cctcctatag aaaccaggga gggcattaat agacctcctc cagtggatgt
     3421 tagggatgtg gttggacgac ctatagatcc cagagaaggc cctggtaggc ctccgttaga
     3481 tggtagggat cattttggaa gacctccagt ggacatgaga gagactcttg tgaggccagg
     3541 tctagaccac cttggccgaa gagaccactt tggctttccc ccagaaaagc cttgggggcc
     3601 tagagatttc gatgagagag agcaccgagt tctgcctgtc tttggtggtc caaagggctt
     3661 acatgaagaa agaggcagat ttcgggctgg aaattatcga tttgatccta gaagtggtcc
     3721 ttggaacaga ggatttggac aagaagttca cagagatttt gatgaccgca gaagaccctg
     3781 ggagaggcag agggataggg atgacagaga ttttgatttc tgcagagaaa ttaatgggaa
     3841 tcgtcttgga cgagatagaa ttcaaaacac ttgggttccc cctcctcatg ctcgggtttt
     3901 tgattatttc gaaggggcca cttctcaacg gaaaggtgag aatgtgcctc aagttaatgg
     3961 tggaaataca gagagacatg ctccgccacc gcctttgcca gtgcagaagg accctgaact
     4021 ctatgagaag ctggcgtctt caggagacgc agacaaggag gagagcggca cagctgctgg
     4081 tgtagagagt gaagcggtgg tagaaagcac agagactgag gggacataac atcgctcagt
     4141 aggtaaaaga aaccttttgt acagttgtca tctctgtaag aggttaatgg ctgactgcac
     4201 cacagttgtt cacgtttatc taccagaact aagttaatct gatgtacgtg ttcacctttc
     4261 tcttaaaata attgtacaac tgacttgtat agacattgtt cttaatatga acatggtagg
     4321 taaacatttt tttatttttc tgataaagta taaatgttgc cccagattct tttaacgtca
     4381 aggagatgct aacagcttgt cgagacttcc tatggaagag aaggttttag acacagtcat
     4441 tgggatgggt atggcaatga catatttcag aacagcaagg tgtggcacat ctccatatct
     4501 ctaggctgct gcagggtttt aaggtgacag acaaagctgt gatattttat gcaaggactg
     4561 gctctagatt cttgaggagc ataatacaga gattttaaaa agtgattttg taaaaatctc
     4621 cactatggtc tctgttactc caaagtaagt gtgtgtgatt tgttcctcat actgcagtaa
     4681 gtaaaaaaga aaagaagcaa acaacataaa cattcaaata cgttttaatg ttgggtgaat
     4741 tttgttttta gatgccaata aaacttattt gtttgaaaaa aaaaaaaaaa aaaa
//
