LOCUS       NM_001037347            4304 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SR-related CTD-associated factor 4 (Scaf4), mRNA.
ACCESSION   NM_001037347 XM_001073074 XM_213658
VERSION     NM_001037347.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4304)
  AUTHORS   Gregersen,L.H., Mitter,R., Ugalde,A.P., Nojima,T., Proudfoot,N.J.,
            Agami,R., Stewart,A. and Svejstrup,J.Q.
  TITLE     SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
  JOURNAL   Cell 177 (7), 1797-1813 (2019)
   PUBMED   31104839
REFERENCE   2  (bases 1 to 4304)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 4304)
  AUTHORS   Yuryev,A., Patturajan,M., Litingtung,Y., Joshi,R.V., Gentile,C.,
            Gebara,M. and Corden,J.L.
  TITLE     The C-terminal domain of the largest subunit of RNA polymerase II
            interacts with a novel set of serine/arginine-rich proteins
  JOURNAL   Proc Natl Acad Sci U S A 93 (14), 6975-6980 (1996)
   PUBMED   8692929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            U49058.1 and AY387086.1.
            
            On May 29, 2008 this sequence version replaced NM_001037347.1.
            
            Sequence Note: This RefSeq was created from transcript data with
            additional support of similarity to the mouse protein encoded by
            AK219509.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-361               U49058.1           11-371
            362-678             U49058.1           373-689
            679-814             AY387086.1         436-571
            815-4304            U49058.1           690-4179
FEATURES             Location/Qualifiers
     source          1..4304
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..4304
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /note="SR-related CTD-associated factor 4"
                     /db_xref="GeneID:245924"
                     /db_xref="RGD:727896"
     exon            1..387
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..3960
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /note="CTD-binding SR-like protein rA4;
                     serine/arginine-rich splicing factor 15; splicing factor,
                     arginine/serine-rich 15"
                     /codon_start=1
                     /product="SR-related and CTD-associated factor 4"
                     /protein_id="NP_001032424.2"
                     /db_xref="GeneID:245924"
                     /db_xref="RGD:727896"
                     /translation="MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVV
                     QIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSENITATFQYLYLC
                     PSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPGAENVTNNEGSPPPPVK
                     VSSELPQAPTNSMPAVPQLPSSDAFAAVDQLFQTTQGQQLQQILQTFQQPPKPQSPAL
                     DSAVMAQVQAITAQLKTAPTQPPEQKTAFDKKLLDRFDYDDEPEAVEDSKKEDAVAVA
                     TTALATAAPPVPAAATPAVAPAVPASSATSPPPPQAPFGYPGDGMQQPAYTQHQNVDQ
                     FQPRMMALQQDSMQHQVPLPPNGQMPGFGLLSAPPPFPPMPQPGMPQPGMPQPGMPQP
                     GLSQPGLPQPGMPQPGMPQPGMPQPGMPQPGLAQPGLAQPGMPQPGMPQPGMPQPGMP
                     QPGMPPTPPVQPTFQPTFQPQNEPHSQKPHQQEMEVEQPCVTEVKRHVPESRKSRSRS
                     PKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQIKS
                     ETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYR
                     ALQKLSRGNYKVNQKSIKIAWALNKGIKADFKQYWDVELGVTYIPWDKVKAEELESFC
                     EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAEASHTEPVSPIPKPVPVPVPALPVPAP
                     ITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPPFWGPGFNP
                     MHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESADSAKMYGSAGPP
                     AAPTSLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGGRPGLIPLQRPPGMPPPH
                     LQRFPMMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGP
                     GPGPGGSEDRDGRQQQPQQQQQQQQQQQQQQQQQQQQPPPQQSQTQQQPAPSQQPAPA
                     QQQPQQFRNDNRQQFNSGRDQERFGRRSFGSRVENDRERYGSRSDERDNSNRERREWG
                     RRSPERDRHRDLEERSRRSSGHRDRDRDSRDRESRREKEESRGKEKHEVADRAGGNKA
                     VEAPLSQVGNTDTVSELNKGEAMATVVKPEESPAEATSSVEPEKDSGSAAEAPR"
     exon            388..471
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            472..516
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            517..678
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            679..814
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            815..954
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1104
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1298
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1407
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1803
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1877
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..2068
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2169
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2283
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2440
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2598
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2599..2767
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2854
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2855..2980
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..4304
                     /gene="Scaf4"
                     /gene_synonym="Sfrs15; Srsf15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctagccggc tgggctagtg tgagccagtg cgtgagggcg cggggggccg tgtcagcgcg
       61 acgcagagcg cagccgccac caccaaacgg acatgttgga gccccgcgct gccgctgcct
      121 cccagctctc ctccagctca cagaactgag caggggcccg ccgcctctgt ctgcgctcga
      181 ccggcccagc ctcgccgcct cggccgcaga cccttcctgc tcggccttcg ccgcttgtcg
      241 cctcccgtcc tcctcccccc cacgccctag ggccctgccg gctcccggtc ctactcagcc
      301 gcggcgcgag gtctatgtga ccggcgggcc cggagcagcc gccgccgcaa cgcgaacatg
      361 gacgccgtca acgccttcaa ccaggagctc ttctcactta tggatatgaa accacccatc
      421 tctagagcca agatgattct tattactaaa gctgctatta aagctattaa gctttataag
      481 catgttgttc aaatagtaga aaagttcatc aaaaagtgta agccagagta caaggttcca
      541 ggcctgtatg tcattgactc catcgtgaga cagtctcggc accagtttgg aactgataaa
      601 gatgtttttg ggccaagatt ctctgagaat ataactgcta cattccagta tttatatctt
      661 tgtccatctg aagataagag taaaatagtt cgtgtgctaa atctttggca aaaaaacgga
      721 gtgttcaaaa ttgaaatcat tcagccgctt ttggacatgg cagcaggaac cagcaatgct
      781 gctccaggag cagaaaatgt caccaacaat gaaggctcac ctccaccccc agtaaaagtc
      841 tcttctgaac ttccacaagc tcccacaaac tccatgcctg ctgtcccaca gctgcccagc
      901 tccgatgcct ttgctgccgt ggatcaactg tttcagacga ctcaaggcca gcagcttcag
      961 cagatccttc agacttttca acaacctcca aaaccacagt ctcccgccct tgacagtgct
     1021 gtgatggctc aggttcaggc tatcacagct cagttaaaga cagctcctac acaaccacct
     1081 gagcaaaaaa ctgcatttga caagaagctg cttgacagat ttgattatga tgatgagcca
     1141 gaagctgtgg aagactcgaa gaaagaggat gctgtcgccg ttgccaccac agcccttgcc
     1201 acggctgcac ctcctgtgcc cgctgcagcc acacctgctg ttgctcctgc tgtgcctgcg
     1261 tcctctgcta cctctccccc tcctccacag gcgccatttg ggtaccctgg agacggcatg
     1321 cagcagccag cgtacacaca gcatcaaaat gtggaccagt ttcaacctcg aatgatggca
     1381 ctgcagcagg atagcatgca gcatcaggtc ccacttcctc ctaacggaca gatgccagga
     1441 tttgggcttc tctctgcacc acctccattt cctcccatgc ctcagcccgg gatgccccag
     1501 cccgggatgc ctcagcccgg gatgcctcag cctgggttgt ctcagcctgg gttgccccag
     1561 cccgggatgc ctcagcccgg gatgcctcag cccgggatgc cccagcccgg gatgccccag
     1621 cctgggttgg ctcagcctgg gttggcccag cccgggatgc ctcagcccgg gatgccccag
     1681 cccgggatgc cccagcccgg gatgccccag cctggaatgc ctccaactcc accagtacag
     1741 ccaactttcc aacctacttt tcaaccacaa aatgaacccc attcacaaaa gccacatcag
     1801 caggaaatgg aagtagagca gccttgtgtc acagaggtta agcggcatgt gcctgagagc
     1861 agaaagtcga gatccaggtc accaaaaaga agaagatcta ggtctggctc taggtctcgg
     1921 agatcccgcc accgtcggtc tcggtcccgg tccagggata ggcgccggca ctcgcctcgc
     1981 tctcgctctc aagaaagacg ggatcgagaa aaagagaggg agcggcggca gaaaggcctc
     2041 cctcagatca agtcagagac tgcaagtgtt tgcagcacca cactgtgggt gggacagctg
     2101 gacaaaagga ctactcagca ggatgttgcc agtctcttag aagagtttgg tccaattgaa
     2161 tcaattaaca tgattcctcc caggggctgc gcctacatag ttatggttca taggcaagac
     2221 gcataccgtg ccctgcagaa actgagccga ggaaactata aagtgaacca gaaatccata
     2281 aagattgcct gggccttaaa caaaggaata aaggcggatt ttaaacagta ttgggatgtt
     2341 gaacttggtg ttacttacat tccatgggac aaagtcaaag ctgaggagct ggagagtttc
     2401 tgtgaaggag gcatgttgga cagtgacaca cttaacccag attggaaagg catccccaaa
     2461 aagcctgaaa atgaagttgc ccaaaatgga ggtgcagaag cctcccacac agagccagtg
     2521 tcccccatcc ctaagcctgt gcccgtgcct gtgcctgccc ttcctgttcc tgcacctata
     2581 acagtaccac ctccacaggt cccaccgcat cagccgggcc ctcctgtcgt tggtgctctc
     2641 caaccgcctg ctttcactcc tcccttaggg atcccccctc caggctttgg ccctggtgtt
     2701 cctcctcctc ctcctcctcc accaccattt tggggcccag gattcaaccc aatgcattta
     2761 ccaccaggtt ttcttcctcc tggaccccca cctcctataa ctccaccagt atccattcct
     2821 ccacctcaca ctccaccaat aagcatccca aacttggtgt ctggggctag aggaaatgcc
     2881 gagtctgctg acagtgcgaa aatgtatggt tctgctgggc cacctgctgc acccacgagt
     2941 ctgcccaccc ctcctgtaac ccagcctgtt tcactgcttg gcactcaagg agttgcacct
     3001 ggtcctgtga ttgggctcca ggcaccctct accggtcttc tcggtggcag acccggcctg
     3061 atcccactcc agcgcccccc aggaatgcct ccaccacact tgcaacggtt ccctatgatg
     3121 ccacctcggc ccatgccacc tcacatgatg cacaggggtc cgccaccagg accagggggc
     3181 tttgctatgc ctccacctca tggaatgaaa gggcctttcc caccacatgg cccctttgtt
     3241 aggcctggtg gaatgccagg gcttgggggc ccaggcccag gcccaggagg atcagaagac
     3301 agagatggaa ggcaacagca accgcagcag cagcagcagc agcagcagca gcagcagcag
     3361 cagcagcagc agcagcagca gcaaccacca ccacagcagt cacagacaca gcagcagcca
     3421 gcgccatccc agcagccagc gccagctcag cagcagccac agcagtttag aaatgataac
     3481 aggcagcagt tcaactcagg tagagaccaa gaaaggtttg gaagaagatc ttttggaagt
     3541 agggtggaaa atgaccggga gcggtatggg agccgtagtg atgagagaga taatagcaac
     3601 cgtgaaagga gagagtgggg aaggaggagc cctgagcggg acagacacag agacttggaa
     3661 gagagaagta gacgctctag tgggcatcgg gacagagaca gggattctag agatagagag
     3721 tcccgtagag agaaggaaga aagtagagga aaggagaagc acgaggtggc agacagggca
     3781 ggtggtaaca aagctgtcga agctcccctt agccaagtgg gaaacacaga cactgtttca
     3841 gaacttaata agggggaggc catggccaca gtggtaaaac ctgaagagtc acctgctgag
     3901 gctacctcat ccgttgaacc tgagaaggat tctggctcag cagcagaggc tcctcgctag
     3961 agactggatt tgacagaatg tgacagtgac acttgggtgt agaacgtgag gtgtacagat
     4021 gctgtataat attcgctcct gctacatcac tccacagtag ttggtgggga ttgtgagcaa
     4081 tttgattgct ttccttctat ttaaaaatag ccacaaaata acaaaaaata ctgaagatat
     4141 attacccctt tttttgctgt aactttttaa aagttttgac ttttaaaagt ttacaaatcc
     4201 taattagaag tgctctctat tttttttttt taatttaaga aaaggtaacg gtgaaaagct
     4261 cctcaaacaa tagggatgtt tttaataaac tctattttcg taac
//
