LOCUS       NM_001414200            5924 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus SR-related CTD-associated factor 1 (Scaf1),
            transcript variant 3, mRNA.
ACCESSION   NM_001414200 XM_008759410
VERSION     NM_001414200.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5924)
  AUTHORS   Cho,K.H., Kim,H.J., Kamanna,V.S. and Vaziri,N.D.
  TITLE     Niacin improves renal lipid metabolism and slows progression in
            chronic kidney disease
  JOURNAL   Biochim Biophys Acta 1800 (1), 6-15 (2010)
   PUBMED   19878707
REFERENCE   2  (bases 1 to 5924)
  AUTHORS   Katsarou,M.E., Papakyriakou,A., Katsaros,N. and Scorilas,A.
  TITLE     Expression of the C-terminal domain of novel human SR-A1 protein:
            interaction with the CTD domain of RNA polymerase II
  JOURNAL   Biochem Biophys Res Commun 334 (1), 61-68 (2005)
   PUBMED   15992770
REFERENCE   3  (bases 1 to 5924)
  AUTHORS   Yuryev,A., Patturajan,M., Litingtung,Y., Joshi,R.V., Gentile,C.,
            Gebara,M. and Corden,J.L.
  TITLE     The C-terminal domain of the largest subunit of RNA polymerase II
            interacts with a novel set of serine/arginine-rich proteins
  JOURNAL   Proc Natl Acad Sci U S A 93 (14), 6975-6980 (1996)
   PUBMED   8692929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 16, 2022 this sequence version replaced XM_008759410.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.1857.1,
                                           SRR26643297.1671.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1923              JAXUCZ010000001.1  104633110-104635032 c
            1924-2037           JAXUCZ010000001.1  104632394-104632507 c
            2038-2095           JAXUCZ010000001.1  104632131-104632188 c
            2096-2193           JAXUCZ010000001.1  104631590-104631687 c
            2194-2294           JAXUCZ010000001.1  104631218-104631318 c
            2295-2410           JAXUCZ010000001.1  104631016-104631131 c
            2411-5083           JAXUCZ010000001.1  104624973-104627645 c
            5084-5166           JAXUCZ010000001.1  104624470-104624552 c
            5167-5385           JAXUCZ010000001.1  104624034-104624252 c
            5386-5514           JAXUCZ010000001.1  104622456-104622584 c
            5515-5924           JAXUCZ010000001.1  104621927-104622336 c
FEATURES             Location/Qualifiers
     source          1..5924
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..5924
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /note="SR-related CTD-associated factor 1"
                     /db_xref="GeneID:56081"
                     /db_xref="RGD:708405"
     exon            1..1923
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2037
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             1930..5706
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /note="CTD-binding SR-like protein rA1; SR-related and
                     CTD-associated factor 1; CTD-binding SR-like rA1; serine
                     arginine-rich pre-mRNA splicing factor SR-A1"
                     /codon_start=1
                     /product="splicing factor, arginine/serine-rich 19"
                     /protein_id="NP_001401129.1"
                     /db_xref="GeneID:56081"
                     /db_xref="RGD:708405"
                     /translation="MEEEDESRGKTEESGEDRGDGPPDRDPALSPSAFILRAIQQAVG
                     SSLQGDLPNDKDGSRCCGLQWRRCCRSPRSEPRSQESGGADMATVLDTAADSFLVELV
                     SILDPPDTWVPSHLDLQPGESEDVLELVAEVRIGDRDPMPLPVPSLLPRLRAWRTGKT
                     VSPQSHASRPACSRHLLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPP
                     PPALPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEE
                     EEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDDSPHREPPPPQTLGAPGTPPQAD
                     STRAEGAPRRRVFVVGPEAEACLEGKVSVEVVTTAGGPALPLPPLPPTDPEIEEGEIV
                     QPEEEPRVAVSLFRAARPRQPPASVATLASVAAPAAPPASAPRAPEGDDFLSLHADSD
                     GEGALQVDLGEPPAPPAADARWGGLDLRRKILTQRRERYRQRSASPGPPPARKKARRE
                     RQRSGDPAPPDSPTWEAKKHRSRERKLGSHSTARRRSRSRSRRRSRSRSADRRRGSHR
                     SRSREKRRRRRRSASPPPAASSSSSSRRERHRGKRREGGKKKKKRSRSRAEKRSGDLE
                     KLPAPVPPSGSDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRPDKTEPRAPSPAPA
                     VSPKREVLYDSEGLSADERGAKGDKDRRRSGAASSSSSSREKASRRKALDGDRGRDRD
                     RSSKKTRPPKDSAPGSGALPKAPPSSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTT
                     PAKDSSSSGLGSIGVKFSRDRESRSPFLKPDERAPAEGVKVAPGSTKPKKTKAKAKAG
                     AKKAKGTKGKTKPSKTRKKVRSGGSSTASGGPGSLKKSKADSCSQAASAKGTEETSWS
                     GEERTTKAPSTPPPKVAPPPPALTPDSQTVDSSCKTPEVSFLPEEASEDTGVRVGAEE
                     EEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAARASQLPTL
                     PPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKPPS
                     TLGVTPAPVPTSLGLPPGPSSYLLPGSLPIGGCGSTPPTPTGLVPASDKREGSSSSEG
                     RGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEI
                     NPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL"
     exon            2038..2095
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2193
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2294
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2295..2410
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..5083
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5084..5166
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5167..5385
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5386..5514
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
     exon            5515..5924
                     /gene="Scaf1"
                     /gene_synonym="Sr-a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgccgggac cggagccgca gcccgagcgg cggggtaaga tggcggcggc ggtccgggcc
       61 gcggggctcg ggcctagcgg ggtgggcggg gcggagtcga gtcgctagtc gtccccgagt
      121 gtcgcccgta tgccacgggg cctggagagc gtagcgtggc accctcggac ccggctgcag
      181 cggccaaggc agtctctgag tagggggcct tcttagggcc tgggacgcgc ccgtaggtgc
      241 cagagggcgt tcgtatggcc tggaccgcgc ctaggcccac cctccatccc attgctgaac
      301 ccggacatgt ctgcaggcgc tgtagatggt ttttatgtgc gaccgtaggc aagggtctgt
      361 tgagaggctt ttggggccat cttgagatct tcactacccc aggagttaag ggggtctgca
      421 gagtcaccta gctcactggg gtatatctgt tagggctggg aagtctctac tggtgctggc
      481 ctctgcattc ggctcatctc tatggatcag ggaccattta ggaggcctag aagctcactt
      541 caaggattag aagtgttaag gtccacctgg aagaaagaga tgtgttccca catagggaga
      601 gggaagcaag cattgtgatg tgcccagagg cataaacgag tctctaaagt ctgggaagtg
      661 ttttatgtgg gggtgattgg gagacaggga tggggtgggg tagtttgaag ggactagaat
      721 cttccaggga ttgcaagaat cccgtctatg tcttagagca aattcaaatg cttttggaga
      781 ctagataatg tgtagagaat aatacaacag aaaacgcggg gcattttatc cagctcaaat
      841 gtacttgcct ttcagaaagt aattaaaaag aaaatggttt taaacaaata agaacctgtg
      901 ttgtcccagt gctgaggaga tagaatcatt ccttggacct gagagtccat tgagctgtct
      961 agaatcatct aatacaatgc tctgcaactt gaccttgata ggaaggaaag actacattat
     1021 tcgatgagat tcaatgcatg ccaacatatg tattttacta atattactcc agtcctgtaa
     1081 actcgaggtt ccatttgaaa cttgggaagt attttccatt atgttttatg tgtaacgagc
     1141 tgtttgtgaa ccactaaatt gctcccagag ccctgtaatt gagggatcac tgatctcaca
     1201 tggtctgcag agccttttac aatggttttg gggatctcca aatctgcagt caggagcttt
     1261 tggtacagtt tcttgtatgt gacagtcagg gctctgtgta acatgtgtat cagactatga
     1321 gagagcagtc ccagagctgg gaattgttga tatacagtat agggaagtct tgaattttag
     1381 cttagagaag cttggatgtg gtagaggggc tgtcagacta aggtatgcct gtgagaatta
     1441 ggaaggaagc tgacgatttg gagagctgaa gccaggaggt tgtggactca gtaggactga
     1501 gaccagggct taggactttt ccttgtgggt gagcaaccag ggaagtaggt tgaggcaaaa
     1561 aggggaaagc tggtctaagg gccactgata aaattattgc taatgtgtat ccagccattt
     1621 atcagtggga atgagtgtga tatacatgct actattttgc cattttcaga taaacactag
     1681 tgtgatttag ggagcctaga gcttttaaga attccaagat taggtgtttt cagagtagca
     1741 ggtttgacag ctgtggggag gtttacagct gtgatgttca tgttttctga agcctcaatc
     1801 aagacatcca ccagtctgaa ggatgctctt tcaactacct gactgggcac tcaaagctca
     1861 gaattcccgt gacatcaccg aggctttggc catgcttcca caggacaggc agctgggtga
     1921 taggtgacca tggaggagga agatgagtct cgaggtaaaa cagaggagtc tggagaggat
     1981 cggggagacg gtccacctga cagagatcct gccctttctc cttctgcctt tattttgcgg
     2041 gccattcagc aggctgtggg aagctccctg cagggggacc tgcctaatga taaagatggc
     2101 tctcggtgtt gtggcctaca atggaggcgc tgctgtcgga gtcctcggtc agagcctcgt
     2161 tcacaggagt cagggggtgc tgacatggcc actgtactgg acacagctgc agatagtttc
     2221 cttgtggagc tggtgagcat cctggatccc cccgacacct gggttcccag ccacctggac
     2281 cttcagcctg gcgaaagtga ggacgtgcta gagctggtag ctgaggtccg tatcggtgac
     2341 agggacccca tgcctctacc tgtgcccagc ctgttgcccc gcctcagggc ctggaggaca
     2401 ggaaagacgg tttctccaca gtcccatgca tctcgacctg cctgttcccg tcacctcctc
     2461 accttgggca caggggatgg agggcctgcc ccaccacctg caccctcctc tgcctcatcc
     2521 tcgccttccc cttccccatc ttcgtcttct ccttctcctc cccctcctcc tccaccccca
     2581 ccccctccag ctctgcctgc cccacgattt gacatctatg atcccttcca ccccaccgac
     2641 gaggcctact ccccaccgcc agccccagag caaaaatatg atccctttga gcccacgggc
     2701 tccaacccca gctcatcagc tgggaccccc tcgccagagg aggaggagga agaagaggag
     2761 gaagaggaag aggagggtct atcacagagc atcagccgaa tctcagagac cctggctggc
     2821 atctatgatg acaacagctt gagccaggac ttcccaggtg atgatagccc ccaccgggaa
     2881 cccccacccc cgcagacgct gggagcccca gggacaccac cacaggctga ctccactcgg
     2941 gccgaagggg ccccacgccg cagggtcttt gtggtgggac cggaggctga ggcatgtctt
     3001 gagggcaagg tttcggtgga agtcgtgacg acggctggtg gaccagcgct gccgctgcca
     3061 ccacttcccc cgactgatcc agagatagag gaaggcgaga ttgtgcagcc tgaggaggag
     3121 cccagggtgg cagtgtcact gttccgtgct gcacgacctc gtcagcctcc tgcctctgta
     3181 gccaccttgg cttcagtggc cgcccctgct gcgcccccag cctctgctcc acgtgcccct
     3241 gagggtgatg acttcctgtc actacatgct gactctgatg gtgagggcgc acttcaagtg
     3301 gacctaggtg agccacctgc accaccggct gctgatgccc gctggggcgg cctggacctg
     3361 cgccgcaaga tcctaaccca gcgacgtgag cgctaccgcc agcgctctgc ctcgccaggc
     3421 ccaccgcctg ctcggaagaa ggctcgaaga gagcggcagc gcagtggcga ccctgcgcca
     3481 ccggattcgc ccacctggga agctaagaag caccgttcac gtgagcgcaa gcttggctcc
     3541 cactccactg cccggcgtcg atcacgctcc cgttcccgcc gccgttcacg ctcccgcagc
     3601 gccgaccgaa gacgtgggag ccaccgctca cgttcccggg agaagcgcag gcgccgacgg
     3661 cgttccgcct ctccacctcc agcggcatct tcgtcatctt cctcgagacg tgagcggcac
     3721 aggggcaaga ggcgtgaggg tggcaagaag aagaagaagc gctcgcgctc ccgggcagag
     3781 aagcgctctg gggacttaga gaagctgccc gcacctgtgc ctccctcggg ctctgaccgt
     3841 gacagccgac gccgcggagc cgtgccacct tctatccagg acctcacgga ccacgacttg
     3901 tttgccatca aacgaaccat cacagtgggt cgcccagaca agacggagcc acgcgcacct
     3961 tcgccagcac ctgctgtgtc cccaaagcgg gaggtcctgt atgactctga gggtctgagt
     4021 gcagatgagc gaggtgccaa gggtgacaaa gatcgcaggc gttcaggggc tgcgtcctca
     4081 tcctcgtcct caagggagaa agcgtctcga cggaaggccc tggatgggga ccggggccga
     4141 gacagggaca ggtcatccaa gaagacacgg ccacctaagg actctgctcc tggctcaggg
     4201 gcgctgccca aagcaccccc aagcagtggc tcctcgtcct cgtcgtcctc ctgctcctct
     4261 cgaaaagtaa aactgcagtc caaggtggct gtgctcatcc gagagggcgt cagcagcacc
     4321 acccctgcca aggattcctc gtcttcgggc ctgggttcca ttggggtcaa gttcagccga
     4381 gaccgtgaga gccgttcacc attcctcaag ccggatgagc gggctcctgc agagggggtc
     4441 aaggtggccc caggcagcac caagcctaaa aagaccaagg ccaaagccaa ggctggggcc
     4501 aagaaagcca aggggaccaa gggaaagacg aagccgtcga agactaggaa gaaggttcgc
     4561 agtggaggca gcagcacggc cagtggtggg cctggttcac tgaagaaatc caaggccgat
     4621 agctgcagcc aggcagccag cgccaagggg acagaggaaa catcatggtc tggggaggaa
     4681 cggaccacca aggcccccag tacccctcca cctaaggtag ccccacctcc acccgcactc
     4741 accccggact cccagactgt ggatagcagc tgcaagaccc ctgaagtctc cttcctacca
     4801 gaggaagcca gtgaggacac tggggtccga gtaggggcag aggaggagga ggaagaggaa
     4861 gaagaggaag aggaggaaga ggagcagcag cctgccacta ccacagccac cagcaccgct
     4921 gcagctgccc caagcactgc ccccagtgcg gggtctacag ctggagactc cggcgcagag
     4981 gacgggccag ctgctagggc ctcccagctg ccaacgctac ccccacccat gccctggaac
     5041 ctacctgctg gtgtggactg tactaccagt ggtgttctgg ccttgactgc actcctgttc
     5101 aagatggaag aagccaacct ggccagccgc gcaaaggccc aggagctgat ccaggccacc
     5161 aaccagatcc tcagccaccg gaagccaccc tctactctgg gggtgacccc agctcccgtg
     5221 cccacttcct tgggtctgcc cccaggcccc tccagctacc tgcttcctgg cagcctcccc
     5281 atagggggct gtggctctac ccctcctacc cctacagggc tagtccctgc atctgacaag
     5341 agagagggca gcagcagctc agagggacgt ggggacactg acaagtatct gaagaagctg
     5401 cacacacagg agcgggcggt agaggaggtg aagctggcca tcaagccata ctaccagaag
     5461 aaagacatca ccaaggagga gtataaggac atcctgagga aggctgtcca caagatctgc
     5521 cacagcaaaa gcggggagat caaccctgtc aaggtgagca acctggtaag ggcctacgtc
     5581 cagcgctacc gctacttccg caagcacggt cgcaagccgg gggacccccc aggacctcct
     5641 cggccaccca aggagccagg gcccccagac aagggtggcc caggcctgcc cctgccccct
     5701 ctctaagact ccttaccctg tccctgtgcc tctgagattc tggacatatt tatggctcca
     5761 cttccccact atgccccccc acagtgggat gatggggaag gttgctgtga ggaagaggag
     5821 agcccaccct agccctatcc ctacccgttg acctagcctg cccccacagt cccagccctt
     5881 ctgtcatgcc ccctccagtt tcattaaaga tttcatgaaa taca
//
