LOCUS       NM_001198590            2193 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus suprabasin (Sbsn), transcript variant 1, mRNA.
ACCESSION   NM_001198590
VERSION     NM_001198590.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   2  (bases 1 to 2193)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 2193)
  AUTHORS   Park,G.T., Lim,S.E., Jang,S.I. and Morasso,M.I.
  TITLE     Suprabasin, a novel epidermal differentiation marker and potential
            cornified envelope precursor
  JOURNAL   J Biol Chem 277 (47), 45195-45202 (2002)
   PUBMED   12228223
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.1817.1,
                                           SRR26643294.1857.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1908              JAXUCZ010000001.1  95128981-95130888
            1909-1980           JAXUCZ010000001.1  95132178-95132249
            1981-2025           JAXUCZ010000001.1  95132370-95132414
            2026-2193           JAXUCZ010000001.1  95133281-95133448
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2193
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /note="suprabasin"
                     /db_xref="GeneID:292793"
                     /db_xref="RGD:1562305"
     exon            1..1908
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..2049
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="suprabasin isoform 1 precursor"
                     /protein_id="NP_001185519.1"
                     /db_xref="GeneID:292793"
                     /db_xref="RGD:1562305"
                     /translation="MHLVNLLSSCCLLALLGALPARAAHEDPIEKAIEGFSRGLSNAE
                     KEVGKALEGINNGITQAGREVERIFDGLSNMGSQAGKTVEHGLDKVAHGINSGVEHAG
                     KEADRLAHGVNHAAGQVGKETNKIIHHGVNQGGSEAGRLGQGAHHAFGQGGSEAEKFG
                     QGVHHAFGQGGREAEKFGQGVHHALGQGGREAEKVGQGIHHAFGQGGREAEKFGQGAH
                     HAFGQGGSETEKFGQGVHHAFGQGGREAEKFGQGAHHAFGQGGSEAEKFGQGVHHAFG
                     QGGREAEKFGQGVHHAFGQGGSEAEKFGQGVHHAFGQGGSEAEKFGQGVHHAFGQGGS
                     EAEKFGQGVHHAFGQGGSEAEKFGQGVHHAFGQGGREAEKFGQGIHHAFGQGGREGGK
                     LVQGANQGLSHAAKEAQQFGHGHGHGYYAAGQTWQEGDKVMYPGVNQAGEEMERFGQG
                     IHHTIEQAGKEAEKVAHGVQTGVNQAGKEAEKVAHGVQTGVNQAGKEAEKVAHGVQTG
                     VNQAGKEAEKVAHGVQTGVNQAGKEAEKVAHGVQTGVNQAGKEAEKVAHGVQTGVNQA
                     GKEAQRVGQGVNHAAGQAGKEAEKLGQGVHHAAGQAGKEMNRLQQDVHNGVNQASKEA
                     NQLLNGPHQGQSGYGGQHGGAAITTAVSGASVNKPFINFPALWRSIAAIMP"
     exon            1909..1980
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2025
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..2193
                     /gene="Sbsn"
                     /gene_synonym="RGD1562305"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccctgcc ttcccaacaa catgcatctt gtcaatctgc tcagctcctg ctgcctctta
       61 gcactcctgg gggctctgcc tgcacgggca gcccatgagg atcccattga gaaggccata
      121 gaagggttca gccgtgggct gagcaacgca gagaaagagg tgggcaaggc ccttgaaggc
      181 atcaataatg gaatcactca agccggaagg gaagtggaaa gaatttttga tggacttagc
      241 aacatgggca gccaggccgg caagaccgtg gagcatggct tggataaggt agcccacggc
      301 atcaacagtg gcgtcgaaca cgcaggaaag gaagcagaca ggttggccca tggggtcaac
      361 cacgccgctg gacaggtcgg aaaggagaca aacaaaatca tccatcatgg ggtcaaccag
      421 gggggcagtg aagcagggag gctcggtcag ggggcccacc atgcttttgg tcagggtggg
      481 agtgaggcag agaagtttgg tcagggggtc caccatgctt ttggtcaggg agggagagag
      541 gcagagaagt ttggacaggg ggtccaccat gctttgggtc agggagggag agaggcagag
      601 aaggttggcc agggaatcca ccatgctttt ggtcagggag ggagagaggc agagaagttt
      661 ggacaggggg cccaccatgc ttttggtcag ggagggagtg agacagagaa gtttggccag
      721 ggggtccacc atgcttttgg tcagggaggg agagaggcag agaagtttgg acagggggcc
      781 caccatgctt ttggtcaggg agggagtgag gcagagaagt ttggccaggg ggtccaccac
      841 gcttttggtc agggagggag agaggcagag aagtttggtc agggggtcca ccatgctttt
      901 ggtcagggtg ggagtgaggc agagaagttt ggtcaggggg tccaccatgc ttttggtcag
      961 ggtgggagtg aggcagagaa gtttggccag ggggtccacc atgcttttgg tcagggtggg
     1021 agtgaggcag agaagtttgg ccagggggtc caccatgctt ttggtcaggg tgggagtgag
     1081 gcagagaagt ttggccaggg ggtccaccat gcttttggtc agggagggag agaggcagag
     1141 aagtttggac agggaatcca ccatgctttt ggtcagggtg ggagagaagg aggcaaactg
     1201 gtacaagggg ccaaccaggg tcttagccat gctgcaaagg aagcacagca gtttggtcat
     1261 ggtcatggcc atggttatta tgctgccggg cagacttggc aagaagggga caaagtaatg
     1321 tatcctgggg tcaaccaggc tggggaagag atggagcgct ttggccaggg tatccaccat
     1381 accattgaac aggctgggaa ggaggcagag aaagtggccc atggtgtcca aactggggtc
     1441 aaccaggccg ggaaggaggc agagaaagtg gcccatggtg tccaaactgg ggtcaaccag
     1501 gctgggaagg aggcagagaa agtggcccat ggtgtccaaa ctggagtcaa ccaggctggg
     1561 aaggaggcag agaaagtggc ccatggtgtc caaactgggg tcaaccaggc tgggaaggag
     1621 gcagagaaag tggcccatgg tgtccaaact ggggtcaacc aggctgggaa ggaggcagag
     1681 aaagtggccc atggggtcca aactggggtc aaccaggccg ggaaggaggc acagagagtt
     1741 ggccaagggg tcaaccatgc tgctggccag gccggaaagg aagcggagaa gcttggccaa
     1801 ggtgtccacc atgctgctgg ccaggccggg aaggaaatga acaggttgca gcaagatgtt
     1861 cataatgggg tcaaccaagc cagcaaggag gccaaccagc tgctgaatgg gcctcatcaa
     1921 ggtcaaagcg gttacggagg ccagcacgga ggggccgcaa tcactacagc agtatctggg
     1981 gcctcggtca acaagccatt tatcaacttc ccagctctgt ggaggagtat cgccgccatc
     2041 atgccctaaa ctgatgccca ggcaacagaa cgcccctgtt gtcacaccag ctgaagcgac
     2101 ccagcagagc tggggcttgg ggagagctgc ctgggtgccc taagggggct gctttgagct
     2161 ttgtgaataa aattgacaca cgatcccttt tca
//
