LOCUS       NM_147135               4111 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus SH3 domain binding kinase 1 (Sbk1), mRNA.
ACCESSION   NM_147135 XM_003748742 XM_006228157
VERSION     NM_147135.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4111)
  AUTHORS   Nara,K., Akasako,Y., Matsuda,Y., Fukazawa,Y., Iwashita,S.,
            Kataoka,M. and Nagai,Y.
  TITLE     Cloning and characterization of a novel serine/threonine protein
            kinase gene expressed predominantly in developing brain
  JOURNAL   Eur J Biochem 268 (9), 2642-2651 (2001)
   PUBMED   11322885
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_147135.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC131843.1, SRR26643298.5138.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               JAXUCZ010000001.1  190260652-190261138
            488-720             JAXUCZ010000001.1  190277272-190277504
            721-923             JAXUCZ010000001.1  190278515-190278717
            924-4111            JAXUCZ010000001.1  190279307-190282494
FEATURES             Location/Qualifiers
     source          1..4111
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..4111
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /note="SH3 domain binding kinase 1"
                     /db_xref="GeneID:113907"
                     /db_xref="RGD:628713"
     exon            1..487
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /inference="alignment:Splign:2.1.0"
     exon            488..720
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /inference="alignment:Splign:2.1.0"
     CDS             495..1748
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /EC_number="2.7.11.1"
                     /note="SH3-binding kinase 1; SH3-binding domain kinase 1"
                     /codon_start=1
                     /product="serine/threonine-protein kinase SBK1"
                     /protein_id="NP_671476.1"
                     /db_xref="GeneID:113907"
                     /db_xref="RGD:628713"
                     /translation="MSVGCPEPEPLHSLPCCGPGAAPVPGAGVPLLTEDMQALTLRTL
                     AASDVTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITN
                     SLSSSPFIIKVFDVVFETEECYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGL
                     ALDFMHSRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPE
                     VCQAGRADGFAVDTGVDVWAFGVLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPG
                     LPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPG
                     DRLPGPLRLEAPGPLKRTVLTESGSGSRPSPPSVGPVVPVPVPVPVPVPEAGLAPPAP
                     PGRTDGRADKSKGQVVLATAIEICV"
     exon            721..923
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /inference="alignment:Splign:2.1.0"
     exon            924..4111
                     /gene="Sbk1"
                     /gene_synonym="Sbk"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagcgccgg gcggagcggg agccgaagcc ggagccgcag cctcagcccg cgccaggccg
       61 gggcaggagc ccgcagagcc gggctgctcg cagcggcggc gcccgaaccc cccagcggct
      121 gagtagtgac ctccatccct gcacgcggct gccgggacgt agcgacagct ccaacccggg
      181 ccccccaaga tctgcttcct acaacctcac acctcaagac tcagagacca agccttgggg
      241 cgctagcccc cctctccgct gctcctgcac accgggactc caaacctagg acagcgagat
      301 cctcttgcta acgagaagcc gcgggcgccc caaagcctcg ggacccgggc gaccaaaccc
      361 cttgcgacgc ctttcgcgtc cctgctcatg gtggtggtgg tgccctgagc ccctctcggg
      421 ccgggcagac gaagaccgac acggcgccca ggccccctgc cgcggcgtcc ccgcggcccc
      481 agcccaggga gaagatgagc gtgggctgcc ctgagcctga accgctccac tccctgcctt
      541 gctgtgggcc gggggccgcc cctgtacctg gtgcaggtgt gcccctcctc acagaagaca
      601 tgcaagccct gaccctgcgc acactggctg ccagcgacgt caccaagcac tacgagctcg
      661 tgcgggagct gggtaaaggg acctacggga aggtcgacct ggtggcttac aagggcacag
      721 gcactaaaat ggccctgaaa tttgtgaata agagtaagac caagctgaag aacttcctgc
      781 gtgaggtgag catcaccaac agcctgtcgt ctagcccctt catcatcaag gtcttcgacg
      841 tggtcttcga gacggaggag tgctatgtct ttgctcagga gtatgcacct gctggggacc
      901 tgtttgacat catccctcct caggtggggc tcccggagga cacggtgaag cgctgtgtgc
      961 agcagctggg gctggcactg gacttcatgc atagcaggca gctggtgcac cgcgacatca
     1021 agcccgagaa tgtgctgctg tttgaccgtg agtgccgccg cgtgaagctg gctgacttcg
     1081 gcatgacgcg gcgcgtaggc tgccgtgtga agcgagtaag cggcactata ccctacacgg
     1141 cgcccgaggt gtgccaggct ggccgcgccg atggcttcgc ggtggacacg ggcgtggatg
     1201 tgtgggcatt cggcgtgctc atcttctgcg tgctcactgg caacttcccg tgggaggctg
     1261 cgtcaggtgc cgatgccttc ttcgaggaat ttgtgcgctg gcagcggggt cgcctgcccg
     1321 ggctgccatc ccagtggcga cgctttacgg agcctgctct acgcatgttc cagcggcttc
     1381 tggcgctgga gcctgagcgg cgtgggcccg ccaaggaggt ctttcgcttc ctcaagcatg
     1441 agctcacatc tgagctgcgg cggcggccat cgcaccgcgc acgaaagcca cctggggacc
     1501 gcctgcctgg gcccctgcgc cttgaggctc cagggccact caagcgcact gtgctcaccg
     1561 agagtggcag cggctcgcgg ccttccccac ccagcgtagg gcccgtggta cccgtgccag
     1621 tgccagtgcc agtacccgta cctgaggctg gtctggctcc gcccgcaccc ccgggcagga
     1681 ccgacggccg tgcggacaag agcaaagggc aggtggtatt ggccacagcc atcgagatct
     1741 gcgtctgagc cgctgcagca cagctgttgc ggggaagccg cgcgctctaa cccgtactag
     1801 ggacaaggag cagccgctgc gcggcagtgg gaaggagtag catagactag gaggcccaga
     1861 caccgggtgg gtggtgggct ggtgacatag ctagcaaaat gaccgtgcat atggccggcc
     1921 tcagcacaga gcagccgagg cccctgacaa aggccgggag cttgtgggcc agactctgag
     1981 ctctggaacc tgaacactcc tggcgcttca taccccttgg cagataaccc tacaatattc
     2041 catccaaacc tgggcacaga aagggggctt tggtgtcagg cagatatggg cacgagatcc
     2101 ttagaaactg gtagggacag gcactaggtt gataacaatg gtgtccagga ggtcagagga
     2161 agaggccaag ccccttacat gtagcaaaag ttgtgtgcag gaacagacct gagtatctag
     2221 tggtacccct cacttcctcc cgctgatggg gactttgaac ccaggaggga gagctattac
     2281 cgcagccacg aggcttttgg gaacagagct ccaatgtgtg cccctcctgg gagtagggga
     2341 gcagatggct ggggaacagg aggctcggca ctcctgtgtc cctagggcta gggagtacat
     2401 ccacagccca gctgctccct ccctgagcac tccacaagca ggggaacaat tgtgtcagct
     2461 attcctgggt ttctgttgga gtcacatgcc tgagcctcgg ttctaggcca gtaccctttc
     2521 aggagtggag cacatcacgg atgggacagg acgccactga aatgacagga gtgaatgtga
     2581 cgtgtgtctg ctgacttcag tgtccacaca cctcaccagg cagctgccaa gagccaggcc
     2641 tatgttttac cacactcctc agggaatccc aggagatacc tgctgttggc tcaggttctt
     2701 aggcagcaaa acaggacttc accctgcccc ggctctcctt tgggagccga cacaagaggc
     2761 ttgaggaacc ctgcaataac cttaaccagg aggctgagcc ttctacctgg caccacgcaa
     2821 ctggccaacc tgggttgcct ctcctaggtc cctccaaaaa gtccctggtc attcaaggag
     2881 gttccatctt ggggctggct ggctagctac aaggggcacc aaccacccct ccgcccagag
     2941 cccccacctc tacacacccc cttactccca ccacaaaggg ctataggtct ccctgccctg
     3001 cctgagtcca gtttacaaac tgtggttgct ccagggcctg gtcctactct cctggggtgc
     3061 caccacttcc ctagtggaca cagggcccac atatgccagg taagtagcaa acccctcctc
     3121 ctgccaagag ccgagtctca gaaggccccc atcactgccc tggcccacct ggggccatta
     3181 ggccctcctt cccagccgct acttctcctc ttgccttagg cctctccacc ctgatctgca
     3241 ataacaagga agcgagattc cacagtagac atcccgcatc ccataagcgc cctctctgtt
     3301 gagatcctgt gtgggaggct tctcccttgt agtatctagg atggtagtcc tcagaagaga
     3361 ctttaggtac gtagcccagc cccattgttt agaggtagca accagcttga ctcaggctgg
     3421 gtcagcctct gtctgctctt gccactgctg gtactgtcta tgtcggttgg gttgggaccc
     3481 tttgcccctt aggagaggtg ttggttacag atgtttacct cagtttgtct ctgttgaaga
     3541 aaccaataat aatagcaaaa aattagtaac atagtagaca tggaggcata gaagacaaac
     3601 cacagaggaa cctcctcctt tgcaattttt ctgtgaagta cagtttgttc acgtatgcac
     3661 acatatgtgc acatctctgt ctcaccccaa ggcaggccaa atcatctatt gacacctgtc
     3721 ccagcctgtg tttccctcac actgccccct gtcctttggt gcttcccagg ggcccctttg
     3781 agctggcttg tggggtgtag gggagttccc tggatgggag gtgaggcctc ggggtagcta
     3841 gaggtctccc accaggttct gtgagcggga gagccctgtg gctgtgtaat gttccctgag
     3901 cccacaggac aggcctggtg gttggcatca gtgtcccagt ctggggcaga gcctgggttc
     3961 tcaagctgta gagcctcaca cccctgtctt cccactccta ccccatgtgt ttgtaaatac
     4021 tctggcttcc tttggcccta aggaggtttt taaatgtgtt atttacttct ctaactatga
     4081 caattgctat aaaataaaaa tttagaaaaa t
//
