LOCUS       NM_001271173            6155 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus SET binding factor 1 (Sbf1), mRNA.
ACCESSION   NM_001271173 XM_001054780 XM_003750392 XM_217021
VERSION     NM_001271173.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6155)
  AUTHORS   Liska,F., Chylikova,B., Janku,M., Seda,O., Vernerova,Z.,
            Pravenec,M. and Kren,V.
  TITLE     Splicing mutation in Sbf1 causes nonsyndromic male infertility in
            the rat
  JOURNAL   Reproduction 152 (3), 215-223 (2016)
   PUBMED   27335132
  REMARK    GeneRIF: Splicing mutation in Sbf1 causes nonsyndromic male
            infertility.
REFERENCE   2  (bases 1 to 6155)
  AUTHORS   Yoshimura,S., Gerondopoulos,A., Linford,A., Rigden,D.J. and
            Barr,F.A.
  TITLE     Family-wide characterization of the DENN domain Rab GDP-GTP
            exchange factors
  JOURNAL   J Cell Biol 191 (2), 367-381 (2010)
   PUBMED   20937701
REFERENCE   3  (bases 1 to 6155)
  AUTHORS   Lorenzo,O., Urbe,S. and Clague,M.J.
  TITLE     Systematic analysis of myotubularins: heteromeric interactions,
            subcellular localisation and endosome related functions
  JOURNAL   J Cell Sci 119 (Pt 14), 2953-2959 (2006)
   PUBMED   16787938
REFERENCE   4  (bases 1 to 6155)
  AUTHORS   Firestein,R., Nagy,P.L., Daly,M., Huie,P., Conti,M. and Cleary,M.L.
  TITLE     Male infertility, impaired spermatogenesis, and azoospermia in mice
            deficient for the pseudophosphatase Sbf1
  JOURNAL   J Clin Invest 109 (9), 1165-1172 (2002)
   PUBMED   11994405
REFERENCE   5  (bases 1 to 6155)
  AUTHORS   Cui,X., De Vivo,I., Slany,R., Miyamoto,A., Firestein,R. and
            Cleary,M.L.
  TITLE     Association of SET domain and myotubularin-related proteins
            modulates growth control
  JOURNAL   Nat Genet 18 (4), 331-337 (1998)
   PUBMED   9537414
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Sep 7, 2012 this sequence version replaced
            XM_001054780.3, XM_003750392.1, XM_217021.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.29810.1,
                                           SRR26643429.28442.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               JAXUCZ010000007.1  122264349-122264531 c
            184-269             JAXUCZ010000007.1  122258048-122258133 c
            270-407             JAXUCZ010000007.1  122257584-122257721 c
            408-566             JAXUCZ010000007.1  122257248-122257406 c
            567-677             JAXUCZ010000007.1  122257056-122257166 c
            678-783             JAXUCZ010000007.1  122256383-122256488 c
            784-916             JAXUCZ010000007.1  122256125-122256257 c
            917-1025            JAXUCZ010000007.1  122255921-122256029 c
            1026-1139           JAXUCZ010000007.1  122255731-122255844 c
            1140-1217           JAXUCZ010000007.1  122255537-122255614 c
            1218-1331           JAXUCZ010000007.1  122255044-122255157 c
            1332-1460           JAXUCZ010000007.1  122254842-122254970 c
            1461-1559           JAXUCZ010000007.1  122254660-122254758 c
            1560-1764           JAXUCZ010000007.1  122254378-122254582 c
            1765-1877           JAXUCZ010000007.1  122254183-122254295 c
            1878-2027           JAXUCZ010000007.1  122253274-122253423 c
            2028-2096           JAXUCZ010000007.1  122252987-122253055 c
            2097-2255           JAXUCZ010000007.1  122252734-122252892 c
            2256-2524           JAXUCZ010000007.1  122252393-122252661 c
            2525-2697           JAXUCZ010000007.1  122252124-122252296 c
            2698-2771           JAXUCZ010000007.1  122251971-122252044 c
            2772-2967           JAXUCZ010000007.1  122251701-122251896 c
            2968-3095           JAXUCZ010000007.1  122251363-122251490 c
            3096-3274           JAXUCZ010000007.1  122250186-122250364 c
            3275-3411           JAXUCZ010000007.1  122249940-122250076 c
            3412-3619           JAXUCZ010000007.1  122249628-122249835 c
            3620-3816           JAXUCZ010000007.1  122249136-122249332 c
            3817-3954           JAXUCZ010000007.1  122248914-122249051 c
            3955-4032           JAXUCZ010000007.1  122246138-122246215 c
            4033-4214           JAXUCZ010000007.1  122245588-122245769 c
            4215-4394           JAXUCZ010000007.1  122245329-122245508 c
            4395-4496           JAXUCZ010000007.1  122244613-122244714 c
            4497-4682           JAXUCZ010000007.1  122244355-122244540 c
            4683-4809           JAXUCZ010000007.1  122244157-122244283 c
            4810-4940           JAXUCZ010000007.1  122243951-122244081 c
            4941-5171           JAXUCZ010000007.1  122243650-122243880 c
            5172-5279           JAXUCZ010000007.1  122239603-122239710 c
            5280-5491           JAXUCZ010000007.1  122239286-122239497 c
            5492-5579           JAXUCZ010000007.1  122238708-122238795 c
            5580-5711           JAXUCZ010000007.1  122238495-122238626 c
            5712-6155           JAXUCZ010000007.1  122237968-122238411 c
FEATURES             Location/Qualifiers
     source          1..6155
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..6155
                     /gene="Sbf1"
                     /note="SET binding factor 1"
                     /db_xref="GeneID:300147"
                     /db_xref="RGD:1307090"
     exon            1..183
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..5810
                     /gene="Sbf1"
                     /codon_start=1
                     /product="myotubularin-related protein 5"
                     /protein_id="NP_001258102.1"
                     /db_xref="GeneID:300147"
                     /db_xref="RGD:1307090"
                     /translation="MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQG
                     IELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVESTQEVMCTEDAT
                     EKEEEAHGGGQAQLSSTAPAQPGQLFAPKTLVLVSRLDHADVFRNSLGLIYTIHVEGL
                     NVNLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLVDSLPVSRCSVALLFRQL
                     GITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLE
                     VLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHNV
                     LSMVLDPELELADLAFPPPTTSASSLKMQDKELRAVFLRLFAQLLQGYRWCLHIVRIH
                     PEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRSTDLFDELVAHEV
                     ARMRADENHPHRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGEASHLRRTHRPFPRL
                     DEGTVQWIVDQAAAKMQGAPPAVKAERRTTVPSGPPMTAILERCSGPHINSARRLEVV
                     RNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAHELHLHVQQNRAVLDHQQFDFV
                     VRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFW
                     EAMFYGDVQTHIRALYLEPSDGVSPTQETGEAQSQDDERSALDVASEQRRLWPTLSRE
                     KQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTN
                     SMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVP
                     DIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGVG
                     GSGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTP
                     VDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGS
                     ALTPGRPPRVTKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPGWEHRGQPPPED
                     QEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAK
                     SEPFRISPVNRMYAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKA
                     VLLRSGGLHGKGVVGLFKAQNTPSPGQAQADSSSLEQEKYLQAVVSSMPRYADSSGRN
                     TLSSFSSAHMGGHVPSPRARVTTLSNPLAASASRWTASRGKWSSVRASGRSSGLGADV
                     GSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIE
                     VFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQISVLVVEL
                     LDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRG
                     AHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRRFRTFLLD
                     SDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTPMFYNYTYAPEDTEVLRPYS
                     NVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSR
                     PRVQPDAISRLLEELQRLETELGRPSERWKETWDRVKAAQRLEGRQDGRGTPSSLLVS
                     AVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSSSRQAARRSTSTLYSQFQTAE
                     SENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTECKGVIDLAEVEAVA
                     PGTPTIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA"
     exon            184..269
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            270..407
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            408..566
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            567..677
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            678..783
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            784..916
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1025
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1139
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..1217
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1331
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1460
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1559
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1764
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1877
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..2027
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2096
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2097..2255
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2524
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2697
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2771
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2967
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2968..3095
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3096..3274
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3275..3411
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3412..3619
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3816
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3817..3954
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3955..4032
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4033..4214
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4215..4394
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4395..4496
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4497..4682
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4683..4809
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4810..4940
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4941..5171
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5172..5279
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5280..5491
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5492..5579
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5580..5711
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5712..6155
                     /gene="Sbf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctggtcag cggcgccgca gaggagcggg ccgggggtgt cccaagtgtg cagcttaggg
       61 ccagcgtcgg gccatgagcg cgccgccatc gaatcctcga gccgtggagc ccgcctgcgc
      121 cccttgccat ggcgcggctc gcggactact tcgtgctggt ggcgttcggg ccgcacccgc
      181 gcgggagtgg ggaaggccag ggccagatcc tgcagcgctt cccggagaag gactgggagg
      241 acaacccttt cccccagggc attgagctgt tttgccagcc cagtgggtgg cagctatgtc
      301 ccgagaggaa tccaccaact ttctttgtgg ctgtccttac tgacatcaac tctgagaggc
      361 actactgcgc ctgcttgacc ttctgggagc cagtggagtc cacacaggaa gtgatgtgca
      421 ctgaagatgc cacagagaag gaggaagagg cacatggagg aggccaagca cagctgtcat
      481 ccacagcccc agcccaacct ggccagcttt ttgctccaaa gactctggtt ctggtgtctc
      541 gactggacca tgctgacgtg ttcaggaata gccttggtct catctatacc atccatgtgg
      601 aaggcctgaa cgtgaacctg gagaatgtga ttgggaatct gctcacgtgc accgtcccct
      661 tggcaggcgg gtctcagaga accatctctt tgggggctgg tgaccggcag gtcattcaga
      721 ccccactggt agactcactg cctgtcagcc gctgtagtgt agccctgctc ttccgccagc
      781 tgggcatcac caatgtgctg tctttgttct gtgctgccct cactgagcac aaagtcctct
      841 tcttgtccag gagctaccaa cgtctagccg atgcttgcag gggcctcttg gcactgctgt
      901 ttcctctcag atacagcttc acatatgtgc ccatcctgcc ggcacagctg ctcgaagtcc
      961 ttagtacacc tacacctttc atcattgggg tcaatgcagc cttccaggca gagactcagg
     1021 agctgctgga cgtgattgtt gccgatcttg atggagggac agtgactgtc cctgagtgtg
     1081 tgcacattcc acccctgcca gagccactac aaagccagac tcacaatgtt ctgagcatgg
     1141 tcctggatcc agagctggag ttggctgacc ttgcctttcc accacctaca acatctgctt
     1201 cctcactgaa aatgcaggac aaggagctcc gcgctgtctt tctgcggctc tttgctcagc
     1261 tcctgcaggg ttaccgctgg tgcctgcaca tcgtgcgcat ccaccccgag cctgtcattc
     1321 gcttccataa ggcagcgttc ttaggccagc gtggactggt ggaggatgat ttcctgatga
     1381 aagtgttgga gggcatggcc tttgcaggct ttgtgtcaga gcgtggggtc ccctaccgtt
     1441 ctacagacct gtttgatgag ttggtggctc atgaggtagc acggatgcga gcagatgaga
     1501 accatcccca ccgcgtcctg cgtcacgtcc aagaactagc agagcaactt tataagaatg
     1561 aaaacccgta cccagctgtg gcaatgcata aagtgcagag gccaggagag gccagccacc
     1621 tgcggcggac ccatcggcca ttcccccggc tagatgaggg cacagttcag tggattgtgg
     1681 accaggctgc agccaagatg cagggtgcac ctccagctgt gaaggctgaa aggaggacca
     1741 ctgtcccttc agggcccccc atgacggcca tcctagagcg gtgcagtggg cctcacatca
     1801 acagtgcccg tcgcctggag gtggtgcgca actgcatctc ctacgtgttt gaagggaaaa
     1861 tgcttgaggc aaagaagttg cttccagctg ttctcagggc cctgaagggg cgagctgccc
     1921 gccgctgcct cgcccatgag cttcacctgc acgtacagca gaaccgtgca gttctggatc
     1981 atcagcagtt tgactttgtc gtccgcatga tgaattgctg cctgcaggat tgcacttctc
     2041 tggatgagca cggcattgcg gctgcactgc tgcctttggt cacagccttc tgcaggaagc
     2101 tgagcccagg ggtaacgcag tttgcatata gctgtgttca ggagcatgta gtgtggagca
     2161 caccacagtt ctgggaggcc atgttctatg gggatgtgca gacccatatc cgggccctct
     2221 acctggagcc ttctgatggc gtgagcccca cccaggagac tggggaggca cagtctcagg
     2281 atgatgaacg atctgccctg gatgtggctt cagagcagag gcgcctatgg ccaaccctga
     2341 gccgtgagaa gcagcaggaa ctggtacaga aggaggaaag cactgtgttc agccaggcca
     2401 tccactatgc caaccgcatg agctaccttc tgctgcctct ggacagcagc aagagccggc
     2461 tgctgcggga gcgggcaggg ttgggagacc tggagagtgc cagcaacagc ctggtcacca
     2521 acagcatggc aggcagtgtg gctgagagct atgacacaga gagcggcttt gaagacgcag
     2581 agacatgcga tgtggctggg gctgtggtcc gcttcataaa ccgctttgtg gacaaggtct
     2641 gcacagagag tggggtcacc agcgaccacc tcaaaggact gcatgtcatg gtgccagaca
     2701 ttgtccagat gcacattgag accctggagg ctgtacaccg tgagagcaag aggctgcccc
     2761 caatacagaa gcccaagctg ctgaggccac gcctattgcc tggtgaagag tgtgtcctcg
     2821 atggccttcg ggtgtacctg ctgccagatg ggcgtgagga gggtgtagga ggcagtggag
     2881 ggggccctgc tctacttcca gctgagggtg ctgtcttcct taccacatac cgcgtcatct
     2941 tcacggggat gcctactgac cccctggtgg gggagcaggt ggttgtccgc tccttccccg
     3001 tggctgcgtt gaccaaggag aagcgcatta gtgtgcagac ccctgtggac cagcttctgc
     3061 aggacgggct gcagcttcgt tcctgcacat tccagctgct gaaaatggcc tttgatgagg
     3121 aggtgggatc tgacagtgct gagctcttcc gaaagcagct ccacaagctt cggtacccac
     3181 cagacatcag ggccaccttt gcattcacac ttggctcagc tctcacacct ggcaggccgc
     3241 cacgagttac caaggacaag ggtccttcat tcagaaccct gtccaggaac ctggtgaaga
     3301 atgctaaaaa gaccattggg cggcagtatg ttactcgtaa gaaatataac ccccctggct
     3361 gggaacatcg gggccagcca ccccctgagg accaggagga cgagatatca gtgtcagagg
     3421 agctggagcc cagcacactg accccgtcct cagccctgaa gccctctgac cgcatgacca
     3481 tgagcagtct ggtggaacgg gcatgttgcc gtgactacca gcgtcttgga ctaggtaccc
     3541 tgagcagcag cctgagccgg gccaagtctg agccctttcg catctctcct gttaatcgca
     3601 tgtatgccat atgtcgcagc tatccaggat tgctgattgt tccccagagc atccaggaca
     3661 atgccctgca acgcgtgtcc cgttgctacc gccagaaccg tttccctgtg gtctgctggc
     3721 gcagtgggcg ctccaaggct gtgttgctac gctctggggg cctgcatggc aaaggtgttg
     3781 ttggtctctt caaggcccag aatacacctt ctccaggcca ggcccaggct gactccagca
     3841 gcctagagca agagaagtac ctgcaggctg tggttagctc catgccacgt tatgctgact
     3901 catcaggacg aaacacactt agtagcttct cctcagccca catgggtggt cacgtgccca
     3961 gtccccgagc cagggtcacc acgctgtcca accctttggc ggcctcggcc tccagatgga
     4021 ctgcgtcccg aggtaagtgg agcagtgtcc gagccagtgg tcgaagcagt gggcttggtg
     4081 ctgatgtggg ctctcggctg gctggcagag acctcctcag tactccccac accaacggag
     4141 cgccacctga ttctggtttt ctgcggccgc agcgtgcagc cctctacatc attggtgaca
     4201 aagctcagct caagggtgtg cgcccagacc ctttgcaaca gtgggagctg gttcctattg
     4261 aagtatttga ggcaaggcag gtgaaagcca gcttcaagaa attgttgaag gcctgtgtgc
     4321 ctggttgccc tgccactgag cccagcccag cctcctttct gcggtcactg gaggactcag
     4381 agtggctgat ccagatacac aagctgctgc agatatcggt gctggtggtg gagctgctag
     4441 actcaggctc ctctgtcctt gtgagcctgg aggatggctg ggacatcacc actcaggtgg
     4501 tatccttggt gcagctcctc tcagacccct tctaccgcac tctggaaggc ttccgcctgc
     4561 tagtggaaaa ggagtggctg tcctttggcc atcgtttcag ccaccgtggg gcccacaccc
     4621 tagctgggca gagcagtggc ttcacacccg tcttcctgca gttcctggac tgtgtacacc
     4681 aggtccattt gcagttcccc atggagtttg agttcagtca gttctacctc aagttccttg
     4741 gttatcacca cacatcccgc cgtttccgga ccttcttgct ggactctgat tatgagcgta
     4801 ttgagctggg actgctgtat gaggagaagg gtgagcgcag aggccagttg gcttgcaagt
     4861 ctgtgtggga atatgtagac cggctaagca agaggacccc catgttctac aactacacat
     4921 atgcacctga ggacacagag gtgctgcggc cctacagcaa tgtgtccaac ctgaaggtgt
     4981 gggatttcta cactgaggag acgctggctg aggggccccc ttatgactgg gagctggccc
     5041 aggggcctcc tgagcctcca gaagaggagc gtcctgatgg aggtgctccc cagagcaggc
     5101 gccgtgtggt ttggccgtgc tatgacagcc gccctcgagt ccagcctgat gccatctcac
     5161 gtctgctgga ggagctgcag cgattggaga cagagctggg acggccttct gaacgctgga
     5221 aagagacctg ggaccgagtg aaagctgctc agcgccttga aggccggcaa gatggacgtg
     5281 gtacccctag ctcattactg gtgtcagctg tgccccacca ccgccgctcg ctaggggtct
     5341 atctacagga ggggcctgtg ggctctactc ttagcctcag cctggacagt gaccagagca
     5401 gtggctcaac cacatccagc tctcgtcagg ctgcccgacg gagcaccagc acgctgtata
     5461 gccaattcca gacagcggag agtgagaaca ggtcctatga gggcaccctg tacaagaagg
     5521 gagccttcat gaagccctgg aaagcccgtt ggtttgtcct ggacaagacc aagcaccagc
     5581 tgcgttacta tgaccaccga gtggacacag aatgcaaggg tgtcattgac ctggcagagg
     5641 tggaagctgt ggcacctggc acacccacca taggtgcccc taagactgtg gatgagaagg
     5701 ccttcttcga tgtgaagaca acacgtcgtg tttacaactt ctgtgcccag gatgtgccct
     5761 cagcccagca gtgggtggac cggatccaga gctgcctgtc ggatgcctga cccctcccgg
     5821 ccctgcccgg gctgctctgc ttccagtcgt tacagaccac taggggtggg cagggccgcc
     5881 ccggccatgt ttacagcccc ggccctcgac agtatttgag gccctgagcc ccccagcact
     5941 tgtgtgtaca gcccccgccc cgccccacct ggccagctct aacttattgt ggtgtcatgg
     6001 ctgagccgtt tagggacgcg gccatggtac agccctgccc tgggcttgta aatagtccac
     6061 cctacccggc ccatcagtgt gctggccctg gccggctggc tgtgctaagt tgtttctaga
     6121 accagagtct atataaagag agaactaacg acaca
//
