LOCUS       NM_145786               1491 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus stabilizer of axonemal microtubules 4 (Saxo4),
            mRNA.
ACCESSION   NM_145786
VERSION     NM_145786.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Baeza,V., Cifuentes,M., Martinez,F., Ramirez,E., Nualart,F.,
            Ferrada,L., Oviedo,M.J., De Lima,I., Troncoso,N., Saldivia,N. and
            Salazar,K.
  TITLE     IIIG9 inhibition in adult ependymal cells changes adherens
            junctions structure and induces cellular detachment
  JOURNAL   Sci Rep 11 (1), 18537 (2021)
   PUBMED   34535732
  REMARK    GeneRIF: IIIG9 inhibition in adult ependymal cells changes adherens
            junctions structure and induces cellular detachment.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  AUTHORS   Cifuentes,M., Baeza,V., Arrabal,P.M., Visser,R., Grondona,J.M.,
            Saldivia,N., Martinez,F., Nualart,F. and Salazar,K.
  TITLE     Expression of a Novel Ciliary Protein, IIIG9, During the
            Differentiation and Maturation of Ependymal Cells
  JOURNAL   Mol Neurobiol 55 (2), 1652-1664 (2018)
   PUBMED   28194645
  REMARK    GeneRIF: IIIG9 is localized in the cilia of adult ependymal cells
            and that its expression is correlated with the process of ependymal
            differentiation and with the maturation of radial glia.
REFERENCE   3  (bases 1 to 1491)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   4  (bases 1 to 1491)
  AUTHORS   Danielson,P.E., Sautkulis,L.N., Foye,P.E., Hedlund,P.B. and
            Carson,M.J.
  TITLE     A novel mRNA expressed along brain ventricles
  JOURNAL   Brain Res Gene Expr Patterns 1 (2), 83-88 (2002)
   PUBMED   15018803
  REMARK    GeneRIF: IIIG9 mRNA is expressed along brain ventricles
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY032665.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY032665.1, BC081718.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1491
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /note="stabilizer of axonemal microtubules 4"
                     /db_xref="GeneID:252958"
                     /db_xref="RGD:708532"
     exon            1..89
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            90..225
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1394
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /note="uncharacterized protein C11orf66 homolog; protein
                     phosphatase 1, regulatory subunit 32"
                     /codon_start=1
                     /product="stabilizer of axonemal microtubules 4"
                     /protein_id="NP_665729.1"
                     /db_xref="GeneID:252958"
                     /db_xref="RGD:708532"
                     /translation="MMGKLPLGVVSPYVKMSSGGCSDPLKFYATCYCTAYGREEFKPR
                     MGSHVGTGYKSNYRPLVSYQPHLDTLDNPAVGEQIHDTSKSVASQSYAPLEVPDGKQP
                     LPWNLHQTTSGYGREKVNIGPLSKEVRKVHFDTQDHGPQTITGLEPKEVPLIHQQQGK
                     GSTEWENSRYGPRFMTSEYNSKYLKESPNHPDLLLKKTIGSKEETGFTEESTKNPIVF
                     QPPSQAYPGDPVLHPGRSITKSDYLPISHPQGNEFLPVLARGSDRDTGYSRVSERSLN
                     PRMPTPSSQPTSMSHRSYQPPQRMQQSNVALLGRESVGNKEPTGFTLNNPSYVRSSYE
                     QDRDQRYLTTYNQGYFENIPKGLDREGWTRGGIQPQKAGAYALSEPVTHMDTTPNPTE
                     TLRHLHPHVGRTLTSVDPFYRDVPHSNRYPTSS"
     exon            226..343
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            344..497
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            498..626
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            627..690
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            691..803
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            804..863
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            864..950
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1064
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1159
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1324
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1403
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1491
                     /gene="Saxo4"
                     /gene_synonym="Iiig9; Ppp1r32"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttggccatc tccacctcag gagagccagc ttctctagag cagctccagc ctcttgtggc
       61 ctctgctgac ctcagagcta cctaagaggg cccgtggggc tctgccctgc agcatcatga
      121 tgggaaaact ccctcttggg gttgtctctc cttatgtgaa gatgagttca gggggatgtt
      181 ctgaccctct gaagttttat gctacttgct actgcacagc ttatggtcgg gaggagttta
      241 agccccgcat ggggagccat gtaggcacag gctacaaatc caactatcga cccctggtct
      301 cctaccaacc acacctggac accctggaca atcctgccgt gggggaacaa atccatgaca
      361 cttccaagtc tgtggccagt cagagctacg ctcccctgga agtgcctgac ggcaagcagc
      421 ccctgccctg gaacctgcac cagacgacct ccggctacgg gcgagagaag gtcaacatcg
      481 gaccactttc caaggaggtc aggaaggtcc actttgacac ccaggatcac gggcctcaga
      541 ctatcacggg actggagccc aaggaggttc ccctgatcca ccagcagcag ggcaagggct
      601 ctacggagtg ggagaactcg cgctatggcc cacgcttcat gacttccgag tataattcca
      661 agtatctcaa ggagtctcca aaccatccag atctcttgct taagaagaca attggttcca
      721 aagaagagac tggcttcacg gaagagtcta ccaagaatcc cattgtcttc cagccgccct
      781 cacaggcata tcctggggac cctgtcctcc atccaggacg gagtatcacc aagtcagact
      841 acctccctat aagtcaccct cagggaaatg agttcctccc tgtgctggcc agaggctctg
      901 atcgggacac tggatacagc cgagtgagtg aaaggagctt gaaccccaga atgcctactc
      961 caagctcaca gcccaccagc atgagccaca ggtcctacca gcctccccag cggatgcaac
     1021 agtcaaatgt tgccctgctt ggcagggagt ctgtggggaa caaggagccc acagggttca
     1081 ctcttaacaa ccccagctat gttcggagtt cctatgaaca agacagagat caacggtacc
     1141 tcaccaccta caaccaaggg tactttgaga acatccccaa ggggctggat cgagaaggct
     1201 ggactcgagg tggcatccag ccccagaaag caggagccta tgccctcagt gagcccgtta
     1261 cccacatgga caccacaccc aaccccacgg agaccctgag gcacctgcat ccccatgtgg
     1321 gaagaacctt gacttcagtt gaccccttct atcgagacgt gcctcatagc aaccgctacc
     1381 caacttccag ctgaatctgg ggggtttgcc atgatgggac aagctccttc ccctacactt
     1441 cccaagatgc cctcggttac tttactaaag aaataaagaa cactgaactg g
//
