LOCUS       NM_001415058            3953 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus SAS-6 centriolar assembly protein (Sass6), mRNA.
ACCESSION   NM_001415058 XM_006233227
VERSION     NM_001415058.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3953)
  AUTHORS   Kobayashi,T., Kim,S., Lin,Y.C., Inoue,T. and Dynlacht,B.D.
  TITLE     The CP110-interacting proteins Talpid3 and Cep290 play overlapping
            and distinct roles in cilia assembly
  JOURNAL   J Cell Biol 204 (2), 215-229 (2014)
   PUBMED   24421332
REFERENCE   2  (bases 1 to 3953)
  AUTHORS   Hashizume,C., Moyori,A., Kobayashi,A., Yamakoshi,N., Endo,A. and
            Wong,R.W.
  TITLE     Nucleoporin Nup62 maintains centrosome homeostasis
  JOURNAL   Cell Cycle 12 (24), 3804-3816 (2013)
   PUBMED   24107630
REFERENCE   3  (bases 1 to 3953)
  AUTHORS   Klos Dehring,D.A., Vladar,E.K., Werner,M.E., Mitchell,J.W.,
            Hwang,P. and Mitchell,B.J.
  TITLE     Deuterosome-mediated centriole biogenesis
  JOURNAL   Dev Cell 27 (1), 103-112 (2013)
   PUBMED   24075808
REFERENCE   4  (bases 1 to 3953)
  AUTHORS   Vulprecht,J., David,A., Tibelius,A., Castiel,A., Konotop,G.,
            Liu,F., Bestvater,F., Raab,M.S., Zentgraf,H., Izraeli,S. and
            Kramer,A.
  TITLE     STIL is required for centriole duplication in human cells
  JOURNAL   J Cell Sci 125 (Pt 5), 1353-1362 (2012)
   PUBMED   22349705
REFERENCE   5  (bases 1 to 3953)
  AUTHORS   Tang,C.J., Lin,S.Y., Hsu,W.B., Lin,Y.N., Wu,C.T., Lin,Y.C.,
            Chang,C.W., Wu,K.S. and Tang,T.K.
  TITLE     The human microcephaly protein STIL interacts with CPAP and is
            required for procentriole formation
  JOURNAL   EMBO J 30 (23), 4790-4804 (2011)
   PUBMED   22020124
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3953)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   7  (bases 1 to 3953)
  AUTHORS   Kleylein-Sohn,J., Westendorf,J., Le Clech,M., Habedanck,R.,
            Stierhof,Y.D. and Nigg,E.A.
  TITLE     Plk4-induced centriole biogenesis in human cells
  JOURNAL   Dev Cell 13 (2), 190-202 (2007)
   PUBMED   17681131
REFERENCE   8  (bases 1 to 3953)
  AUTHORS   Habedanck,R., Stierhof,Y.D., Wilkinson,C.J. and Nigg,E.A.
  TITLE     The Polo kinase Plk4 functions in centriole duplication
  JOURNAL   Nat Cell Biol 7 (11), 1140-1146 (2005)
   PUBMED   16244668
REFERENCE   9  (bases 1 to 3953)
  AUTHORS   Leidel,S., Delattre,M., Cerutti,L., Baumer,K. and Gonczy,P.
  TITLE     SAS-6 defines a protein family required for centrosome duplication
            in C. elegans and in human cells
  JOURNAL   Nat Cell Biol 7 (2), 115-125 (2005)
   PUBMED   15665853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 20, 2022 this sequence version replaced XM_006233227.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1714080.1,
                                           SRR26360181.2423269.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               JAXUCZ010000002.1  207231896-207232065
            171-231             JAXUCZ010000002.1  207240550-207240610
            232-311             JAXUCZ010000002.1  207242263-207242342
            312-416             JAXUCZ010000002.1  207242726-207242830
            417-588             JAXUCZ010000002.1  207244076-207244247
            589-654             JAXUCZ010000002.1  207244951-207245016
            655-774             JAXUCZ010000002.1  207246218-207246337
            775-966             JAXUCZ010000002.1  207249879-207250070
            967-1161            JAXUCZ010000002.1  207252399-207252593
            1162-1251           JAXUCZ010000002.1  207252698-207252787
            1252-1431           JAXUCZ010000002.1  207252864-207253043
            1432-1513           JAXUCZ010000002.1  207253371-207253452
            1514-1650           JAXUCZ010000002.1  207254152-207254288
            1651-1779           JAXUCZ010000002.1  207255656-207255784
            1780-1877           JAXUCZ010000002.1  207259977-207260074
            1878-1972           JAXUCZ010000002.1  207261667-207261761
            1973-3953           JAXUCZ010000002.1  207261857-207263837
FEATURES             Location/Qualifiers
     source          1..3953
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     gene            1..3953
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /note="SAS-6 centriolar assembly protein"
                     /db_xref="GeneID:310807"
                     /db_xref="RGD:1306255"
     exon            1..170
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..2076
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /note="spindle assembly 6 homolog"
                     /codon_start=1
                     /product="spindle assembly abnormal protein 6 homolog"
                     /protein_id="NP_001401987.1"
                     /db_xref="GeneID:310807"
                     /db_xref="RGD:1306255"
                     /translation="MSQVLFQQLVPLLVKCKDCEERRGSVRVSIELQSLSNPVHRKDL
                     VIRLTDDTDPFFLYNLVISEEDFQSLKLQQGLLVDFLSFPQKFIDLLQQCMQEHVKET
                     PRFLLQLTSSAALLDNSPVFLNVVETNPFKHLIHLSLKLLPGNDVEIKKFLAGCLKCS
                     KEEKLSLTKSLDDVTRQLHITQETLSEKMQELDKLRSEWASHTAALTNKHSQELTNEK
                     EKALQTQVQYQQQHEQQKKDLEALHQRNIHQLQNRLSELEAANKELTERKYKGDSTVR
                     ELKAKLAGVEEELQRTKQEVLSLRRENCTLDTECHEKEKHINQLQTKVAVLEQEIKDK
                     DQLVLRTKEAFDTIQEQKVALEENGEKNQIQLGKLEATIKSLSAELLKANEIIKKLQG
                     DLKTLMGKLKLKNTVTIQQEKLLAEKEEMLQKERKESQDAGQSLRAKEQEVCRLQEQL
                     ETTVQKLEESKQLLKNNEKLITWLNKELNENQLGRKQDTLGASATPPTHSASNTVRSG
                     LSPSLNVVDSRLNYPSCGIGYPVSSAFTFQNAFPHAVVAKNTSHPVSGPKVQFSLQLT
                     KQSTSSGDGQPGAAVNRSASADKENGENLGLESKYLKKREDSIPLRGLSQNLFSNSDH
                     QKDGMLGALQTSSKPTVLPPSSSYFPGPLPSS"
     exon            171..231
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            232..311
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            312..416
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            417..588
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            589..654
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            655..774
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            775..966
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1161
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1251
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1431
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1513
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1650
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1779
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..1877
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1878..1972
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..3953
                     /gene="Sass6"
                     /gene_synonym="RGD1306255"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgccaaa ctcaaactta gtctggagca gtacttcttt taagctggta ccgcgggcca
       61 ggcctactgg gctttttcac tcacgggtcg gggcagcggt ccgacatgag tcaagttctg
      121 ttccagcaac ttgttccctt gctagtgaaa tgcaaagact gcgaggagag gagagggagc
      181 gttagagtga gcattgaact acagtcactg tctaatccag tacacagaaa ggatctagtc
      241 atccgtctga ctgatgatac agatccattt tttctgtata accttgttat atccgaggaa
      301 gactttcaaa gtttaaaatt gcagcaaggt ctcctggtgg acttcttatc ttttccacag
      361 aagtttatag acctccttca gcaatgtatg caggagcatg tgaaagagac tccaaggttt
      421 ctgctgcagc tcacgtcttc agctgctctt ttggataact cgccggtgtt tttaaatgta
      481 gtggagacaa atccttttaa gcatcttatt cacctgtcac taaagctttt acctggaaat
      541 gatgtagaaa taaagaaatt tctagcagga tgcttgaaat gtagcaagga agaaaaatta
      601 tcactgacta aatcactaga tgatgttacc aggcaactgc acattacaca agagacactc
      661 tcggaaaaga tgcaggaact agataagttg cggagtgagt gggcctcgca cacagcagcg
      721 ctgaccaata agcactccca ggagttaaca aacgagaagg agaaagcctt gcagacacaa
      781 gttcagtacc aacagcagca tgaacaacag aaaaaggatc tggaagccct ccatcaacga
      841 aatatccacc agctacaaaa cagattgtct gagttagagg cagctaataa agagctcacc
      901 gagaggaagt ataaaggaga ctccactgtc agagaactaa aagcgaagct tgctggtgtg
      961 gaagaggagc tgcagcggac caagcaagag gtcctttctc tgagaagaga gaattgtact
     1021 ctggatactg aatgccacga gaaagaaaag catattaacc agctacaaac aaaagtggcc
     1081 gttttagaac aggagatcaa ggataaagac cagcttgttc tgagaacaaa agaagcattc
     1141 gatacaatcc aagagcaaaa ggtggcttta gaagaaaatg gtgagaaaaa tcagatacaa
     1201 ttgggaaaac ttgaagctac aataaaatca ttatcagcag aacttctaaa ggcgaatgag
     1261 attatcaaga agttacaagg agatcttaaa actctgatgg gtaaattgaa actgaagaat
     1321 acagttacta ttcagcaaga aaagctattg gctgagaaag aagaaatgct acaaaaggag
     1381 cgaaaggaat cacaggatgc tgggcagtct cttcgggcca aagagcaaga ggtatgcaga
     1441 ttacaagaac aattagaaac tacagttcag aaacttgaag aaagtaaaca acttttgaaa
     1501 aataatgaaa aattaatcac atggctaaac aaagaactaa atgaaaacca gctgggaaga
     1561 aagcaagaca cactgggggc ctctgccacc ccacccacac attctgctag caacaccgtc
     1621 agaagtgggc tttctcccag cctgaatgtg gttgatagta gactaaatta cccaagctgt
     1681 ggaattggct atcctgtctc gtctgcgttc acattccaga atgcttttcc tcatgcagta
     1741 gttgccaaaa acaccagcca tccagtctct ggaccaaagg tgcagttcag cttgcagctg
     1801 acaaagcaaa gcacgtcgtc gggagatggg cagccgggag cggctgttaa caggtctgct
     1861 tcagctgaca aggagaatgg tgaaaattta ggattggaat ccaaatactt gaagaaaaga
     1921 gaagatagca ttcctttacg tggactcagc cagaatctgt ttagtaattc agaccatcag
     1981 aaagatggca tgctgggagc gctgcagaca tcttccaaac ccacagtcct gcccccatct
     2041 tcatcgtatt ttcctgggcc attaccaagt agttaatccg acacctttca ctgcttactg
     2101 acagtttaga aactcaagtg acttaacaga ccattaataa caccagtctt ttcttgttcc
     2161 tgttaggtca tttgtatcct ttataatagt gctgccattg acaaacttag gacattgata
     2221 aggactctga gtaaatggta tttttttctg tgagcacaac agaatattta aaaaaaaaaa
     2281 aagtcactga attgtatcgg atttttacca gttggtctga atagggacac taaatcaaag
     2341 ataagcctgc agagaatagt agtaacaagc tgaagaagac ttgtgattca tactatcatt
     2401 tctgttatta aaaaattatt aatttgccac ctgagagttg ggagggcttc cacctgtgat
     2461 cattggtctt tacactgagt tagtatacta ctttcaaagg gtttttttgt ttgtttttct
     2521 ttgagatagg gtctattatg tagttcaggc tgcagaacat gccatgtatg tagactaggc
     2581 tggtctgaaa tccagatccg cctgcctctg tctcccaaca cctggtatgt actactgagc
     2641 ctgatttaca caatgtattt tggtttattc tttctcctct caggtgctct ccaatttcct
     2701 acccacccaa ttccatattt tctcccttaa aaagaaaatt aaaataacca accagtaaga
     2761 taaaaatatc aaaccaaaac caatggattt gaccttgtgt tagtcaacaa ctcctgggtg
     2821 tgggtgtttg gaatttggct gatatactcg atagtcttaa gcactttgag tgaaagttaa
     2881 gtattcgtag tgagcggatt attttctctg acatgtttga tctatgaaat gattttatat
     2941 aaaaattggg cagtatattt acatgactga aatgctttag tcgtctgggc tgagcatagt
     3001 tgattttgac acttccatac aagatcatca gtggaatagc accataaaag tttttataat
     3061 atacttttac aatatttgtg ctcagtgtta ataaagcagg caagttaact attggaagtt
     3121 acaactttct cattattaaa aacttccaag aattattcct tggaaattaa gtagtttcaa
     3181 aaaacaaaac aaaaccaaaa ctaacactca gtaatcttag aggtctagtt ttgttttctt
     3241 gttgataaca ccccaaatct tatctgtaaa atgtaacaat catgtgatat tttcaaagtt
     3301 tcaagaggct ggcgagatgg ctcggttgtt gattagcact aaatatcttt cagaggacat
     3361 gggggttcta gtcccagaac ccacatggca gctcatgatt gtatgtcacc cacagtgcat
     3421 caggcatgtg gtttctaaat atacactgtt gaagacattt tgagactgag acatattaac
     3481 tatgagggct acaggagaac agggatcttt agtctcactt tcaggatgat agcatctgcc
     3541 atctatcttc aacaaggaag ggctgaagta gaagttcagt gatgtaaggc tattggtaca
     3601 actacttgag agcacttatt ctggaaagaa gcctcttgcc agcacaggac tgttgtaaat
     3661 actgtaaagt aagcgtcagt gcttgcggcc ggctttggga agggattaag acgtatctat
     3721 tagctttgtg aagagatacc ctccccttac tatttataaa catttccaag ataggctgtt
     3781 ggtgagctgt ctgtgctaag tgtccaccac acggatagtg ctaactctct gctctacctc
     3841 tcagcttttg tttgaaattg ttttgtataa ctgtacatgt gttaataatc aaaatgttgt
     3901 tctttgctat ttctgaaaac tgtgaccttt gttaataaag cactgaaacc tca
//
