LOCUS       XM_039101479            8019 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus SAM and SH3 domain containing 1
            (Sash1), transcript variant X1, mRNA.
ACCESSION   XM_039101479
VERSION     XM_039101479.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039101479.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8019
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8019
                     /gene="Sash1"
                     /note="SAM and SH3 domain containing 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 27 ESTs, 3 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     34 samples with support for all annotated introns"
                     /db_xref="GeneID:365037"
                     /db_xref="RGD:1566017"
     CDS             713..4906
                     /gene="Sash1"
                     /codon_start=1
                     /product="SAM and SH3 domain-containing protein 1 isoform
                     X1"
                     /protein_id="XP_038957407.1"
                     /db_xref="GeneID:365037"
                     /db_xref="RGD:1566017"
                     /translation="MEEDAGAASPAPEPEVDPAREPEPEPESEPEAGTSEAFSRLWTD
                     VMGILDGSLGNIDDLAQQYADYYNTCFSDVCERMEELRKRRVSQDLDVEKPDASPTSL
                     QLRSQIEESLGFCSAVSTPEVERKYPLHKSNSEDGCVGKADWKKKNKYFWQNFRKNQK
                     GIMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSS
                     ALDPADWPDGSYPTLDGSSTCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVE
                     EMKKPSTEGGEEHVFESPPVQDERSALYSGVHKKPFFYDGSPEKPPEDSADSLTPSPS
                     SSSLETWGAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKK
                     GLGSLSHGVSTDGVFFYDSHRRRHHFLVSLEEVQSIRKQIRLKKTDTNYSCSRTFLCQ
                     RPSRKGVNGTTCDLLPRPKPKGGGGCGFPGRRGRGRTSVSEFNITYVVERSLYSHLNL
                     TQLVRPASDRTLSKAEKQDLRRCLLEEDEEAKRKWAATVDRCTKRVLLRIHQKSRTCS
                     FGGFDLTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPSASRISLGKKVKSVKETMRKRM
                     SKKYSSPVTEQDSGLDGTPGSPTSVKPDSEHMDKPKLKAGGSVESLRSSLSGQSSMSG
                     HTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGD
                     IIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLNEEEEKPKRPTRRRRKGRPSQPKSVE
                     DLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEY
                     DSNSDQSGSQEKLLADSQGLSGRSPRDSGCYESSENLENGKTQKPSALSTKSSTESNL
                     KSFNRSQPGNYPTLPLTKSGEVRKQGEESRLGRGLAPDTAKCCDVPCVTGLSKNRRSL
                     PVSICRSCETLEGPEPVESWPRSHSLDDLQGDADVGKDVPTEKPETCPENVPEVPQKA
                     SACTSKALPRGRDPTAEDVMFLTQSKRFSDPPKTMAKKLEGSAVASNLGIAPPQCIPR
                     NFEAQPPVKPGLTRTSLEGLRKGHDHHSLGTKEGVDGEQSTPETRTQSRHPSQPPPVP
                     AKKSRERLANGLHLVPSPEAPILPLKKASPASPVSPSDCPSPREPRSSSGTEPGSPVC
                     TRPPPWLAELPESTSLQEHGVKLGPVLSRKVSCIRGVDLEMLTENKLQAEGIDLTEEP
                     YSDKHGRCGIPEALVQRYAEDLDQPERDVAANMDQIRVKLLRKQHRMAIPSGGLTEIC
                     RKPLSPGCVTSVSDWLISIGLPMYTSTLSDAGFSALSQVPSLSHTCLQEAGITEERHI
                     RKLVTAARLFKLPPSPEAM"
ORIGIN      
        1 tgtcaccata ctgactcttc atgaacttgg gctcagcgag cagcttaaag attaactttc
       61 tgcggaaggc gcgggctgag tatagcgcga ttggggactt gtgcagggcc cggggcccgt
      121 ggcggggtcg cgctttcaaa aggcgatttg ttggcggcgc tgaagctcat ttccatgcaa
      181 agcgcctgac atcagagcac cttttgttgc taaacgcttt cttgagcccg ggaggggagg
      241 gagtcatgtg gagttggaag agctcattct ggagagaggg gtccaggact tgttagctcg
      301 ggtccacagg cgtcactgtc ccctgccgga ccctgagcag actctccaat agaggcaagt
      361 cgtgtgccac tcggagccag ttcccggagc aggacgcagc gcccgtgagt tggggctcct
      421 ggatcccttg tcctgagagc tccccgccgc tgccagtggt gcggactcgg ctccagctac
      481 cctgttgctg cgcctggccg ggctaggaaa agtttctgga gttgtcaatc gcgttcgccg
      541 cctatctagg tgcctagtcc tggcagtggt gctcgtaccc ggcggagcct agggcatgcg
      601 acgcgggggc gcggcccagt gacgccgcgg gcggggacct tgtaccccga cggcggacgc
      661 gctgctgcgg gccgtgggca gcgcggggac ccggaggcac ggggacgcgg ccatggagga
      721 ggacgcggga gctgctagcc cggcgccgga gccggaggtg gatccagccc gggagccgga
      781 gccggagccc gagtctgagc ccgaggccgg cacgtccgag gcgttctccc gcctctggac
      841 cgacgtgatg ggcatcctgg atggttccct gggaaacatt gatgacctgg cccagcagta
      901 cgcagattat tacaatacct gcttttctga tgtgtgtgag cggatggagg agcttcggaa
      961 acggcgcgtt tcccaggacc ttgatgtgga gaaacccgac gccagcccca cgtcacttca
     1021 gctgcggtcc cagatcgaag agtccctagg cttctgcagc gcggtgtcaa caccagaagt
     1081 ggaaagaaag taccctctcc ataaatcaaa ctcagaagac ggctgtgtag gcaaagcaga
     1141 ctggaagaag aaaaacaaat acttctggca gaatttccga aagaaccaaa aaggaataat
     1201 gagacagact tcaaaaggag aagatgtggg ctatgtggcc agcgagataa ccatgagcga
     1261 cgaggaacgg atccagctaa tgatgatggt caaggagaaa atgatcacca ttgaagaagc
     1321 gctcgccagg ctgaaggaat atgaggccca gcaccgccag tcttccgccc tggaccctgc
     1381 ggactggccc gacggctcct accccacgct ggatggttcc tccacctgca actcaagaga
     1441 acagtcggat gatgagaccg aggagtcggt gaagtttaag aggttacaca agctggtaaa
     1501 ctctacccga agagtcagaa agaaactaat tagggtggag gaaatgaaaa agcccagcac
     1561 agaaggtgga gaggaacatg tgtttgagag tcccccagtc caagacgaaa gatctgcgct
     1621 ctactcagga gtgcacaaaa agccattttt ctatgatggc tctcctgaga aacctccaga
     1681 agacagcgca gattctctta ccccatctcc atcatccagt agcctggaga cctggggcgc
     1741 tggccggaag ttggtcaaaa ccttcagcaa aggagaaagc cgggggctga ttaagccccc
     1801 taagaagatg gggacattct tctcctatcc ggaagaagag aaggcccaga aagtgtcccg
     1861 ctccctcaca gagggggaaa tgaagaaagg tcttgggtct ttgagtcacg gggtaagtac
     1921 cgatggtgtt ttcttctatg acagtcaccg gcgcaggcac cactttctgg tgtccctgga
     1981 agaggttcag agtatccgca agcaaattcg cttgaagaaa acggatacta actactcctg
     2041 ttccagaact tttctctgcc agcgtccctc cagaaaagga gtaaatggca ccacctgtga
     2101 cctgctgccc cggcccaagc ccaagggggg cggcggctgc ggcttccccg gcaggcgggg
     2161 ccgagggcgc acctcggtca gcgagttcaa tatcacctac gtggtggagc ggagcctcta
     2221 cagccacctg aacctgaccc agctcgtgcg tcctgcctcg gacaggacgc tgagcaaggc
     2281 ggagaagcag gacctgaggc ggtgcttgct ggaggaggac gaggaggcaa agaggaagtg
     2341 ggctgccacg gtggaccgct gtactaaaag ggttctcttg agaatccacc agaagtctag
     2401 aacttgtagc tttggtggat tcgacctgac caaccgttct ctgcacgttg gcagcaataa
     2461 ttctgacccc atgggtaaag agggagattt cgtgtacaaa gaggtaatca aatccccttc
     2521 tgcctcccga atctctctcg ggaaaaaggt gaaatcagtg aaagagacca tgaggaagag
     2581 gatgtctaaa aaatacagca gccccgtcac agagcaggac tcggggctcg acgggacacc
     2641 cggctccccc acctcagtaa agcctgactc tgaacacatg gacaagccca agctcaaagc
     2701 cgggggctct gtagaaagcc ttcggagctc tctgagtggc cagagctcaa tgagtggtca
     2761 tactgtgagc accacggact cctccaccag caacagggag agtgtcaagt cggaagatgg
     2821 tgacgatgag gagccaccct atcggggtcc cttctgtggg cgtgcccgag tgcacaccga
     2881 cttcaccccc agtccctatg acacagactc tctgaagctc aagaaaggag acatcattga
     2941 cataatcagc aaaccgccga tgggtacctg gatgggcctg ttgaacaaca aagtcggcac
     3001 atttaagttc atctacgtgg atgtgctaaa tgaggaagag gagaagccca agcgccctac
     3061 caggaggagg aggaagggaa gaccatccca gccaaagtct gtggaggatc tcctggatcg
     3121 gatcaacctg aaagaacata tgcccacctt tctgttcaat ggctatgaag acctggacac
     3181 cttcaaactc ctggaggaag aagacttaga tgaattaaat atcagggacc cggaacacag
     3241 agcagttctc ttgacggcgg tggaactgtt gcaggaatat gacagtaaca gtgaccagtc
     3301 tggttctcag gagaagctgc tggccgacag ccagggcctg agtggacgtt cccctcgaga
     3361 ctccggatgc tatgaaagca gcgagaactt ggaaaacggc aaaacacaaa aacccagcgc
     3421 tctgtccacc aagtcatcca cggagtccaa cttaaagtct ttcaacagga gtcagccggg
     3481 caactatccg acattgcctt taacgaaatc aggggaggtg cgcaagcagg gagaggagag
     3541 caggctggga agaggtctag ccccggacac tgccaagtgc tgtgatgtac cctgtgtgac
     3601 tggtttgagt aaaaaccgaa ggagcctccc ggtctccatc tgtcgcagct gtgaaaccct
     3661 ggagggtcct gagcccgtgg aaagttggcc ccgatcccat tccctggacg accttcaggg
     3721 agatgctgat gttggtaagg atgtgcctac cgagaagccg gaaacctgtc cagagaatgt
     3781 accagaagtg ccacagaagg catctgcctg cacctccaag gctctgcccc gaggccgaga
     3841 tcccactgca gaagatgtga tgtttctgac ccaaagcaag agattttccg accctccgaa
     3901 aacgatggct aagaaactgg agggctccgc ggtggcctcc aaccttggca tagctcctcc
     3961 tcagtgtata cccagaaatt ttgaggctca gcctcctgtt aaacctggct taacaaggac
     4021 gtctcttgag ggtctcagaa aaggacatga ccaccactcc ctgggcacca aagaaggggt
     4081 agatggggaa cagagcaccc ctgagaccag gacgcaatcc agacatccat cgcagccccc
     4141 gcctgtgccg gccaagaaaa gccgagagcg cctggccaat ggcctgcacc tggtccctag
     4201 cccagaggcg cccatcctgc cactgaagaa ggccagccct gccagccccg tcagccccag
     4261 cgactgcccc tctccccggg agcccaggtc ttcctcgggg actgagccag gcagcccagt
     4321 gtgcacgaga cctccaccct ggctggccga gctgccggag agtaccagcc tgcaggagca
     4381 cggtgtgaag ctgggcccag tgctgagcag gaaggtttcc tgcatccggg gtgtggacct
     4441 agagatgctg acggagaaca agctacaggc tgagggcatc gatctcactg aggagcccta
     4501 ctctgataag catggccgtt gtgggatccc tgaagccctg gtgcagagat acgcggagga
     4561 cctagatcag cctgagaggg atgtcgccgc caatatggac cagatccgcg tgaagctgct
     4621 ccggaaacaa catcggatgg cgatcccgag tggcgggctg acggaaatct gcagaaagcc
     4681 cctctctccc ggatgtgtta cgtccgtgtc ggattggctc atctccatcg gcctgcccat
     4741 gtacacgagc acgctttctg acgcagggtt cagtgcgctg agccaagtgc cttccctgtc
     4801 ccacacttgc cttcaggagg ccggcatcac agaggagaga cacataagga aactggtaac
     4861 cgcagccaga ctcttcaaac tgccaccaag ccctgaggcc atgtagccag gcccaccgtg
     4921 gccctccctg gacaagagcc agcccttcac tgtgccctcc atctctgctg gggttgacct
     4981 gactgggaag aaaagtaccc acttggggct cacgaactgc aggattagga ttcagaactg
     5041 agggcccact cttcctgaaa agtcctcctc tcccacccct cgaggacatc gatgtggctc
     5101 tctttgatgc ccaaaggcag gacaagcact tggttctgtt ttcagacacg gaagagctaa
     5161 gatgccgact ccttgctaac acggttcgat cggtctgtct ttgtgctggc agaggactag
     5221 gaggacagac agcctgctcg tgtctgatcg tgcccttgcg cgtatctgtt ggtcacccgg
     5281 ctggatgccc gagcccgatg ggcttagcta ggccaaagca acagactctg gagttactgt
     5341 atactattga ccctgctcat ctgttcaaaa gctacaacag ctgactctac caagaacaga
     5401 gcagtcctcc tctcctgtag ataaacgaga gacattttaa ttgctttcta gcaattagct
     5461 tttatttgcc ttaatataaa cttttaacca gttatctatc tagtgtccac aacccttact
     5521 taaccctagt tccagatctc cagcttagac tgccatctaa cgtgtttggg atgtttccag
     5581 caaaaatagc ctttttcttt cttttttttt tctttttttt tcttttaaaa acaatctctt
     5641 tctaacatgg cttatcttat aggggtgact accaggcaca catttcacgt tgacttttag
     5701 tttctaaact aactagaaat tcagtaaacg tcggtcggga ttcacagagg ggcacgcgtg
     5761 ttcccgtgca tgtgaagtaa ctgcccatca gtctactcac tttactgagt gccgccaagg
     5821 tggccatggt gttgtaggat ttacacaaag tcctgacccc atccatcccc aagtccactc
     5881 atcagctaac ggatcacctt tgcagaaagt catcgtaatg ttgcgtattt cagaaagata
     5941 tttttttttc taaaaaggga agtagtttac actcagttct ttaaagttct ttttgtctgt
     6001 gtgtttttaa tttttttttc tttttggcca gttctataat tattattatc tttcatttgt
     6061 tacctagata agtgttttaa ttcaagcaaa ggttcattat ggagccagat aaaccacatc
     6121 cgccgtgtgt taaatactgc atattttcag ctggttttct tttttttccc caatggtgat
     6181 ttccacgtaa tctaccctcc tttggtctgg cgcttggctt cctagcagtt ggcagattta
     6241 gacaggtaca cgtgctccat tgcttacacg gaccatgtga agtctcaagt taccgtggaa
     6301 acactctgca tacaaggcct ggatcagtcc tctgatagtt cattgggtta ttaacatttg
     6361 atttccctca ggagagaagg gcaagttatt ttattaataa caaagccatc ctggccatat
     6421 ggtttataga gctggatcca tgtggatctc aggtgacccc cacccccatt ttagtatgca
     6481 ttgaaaagta ataataacga tgtttggttt gttcgcttcc attcgccttc tataagatgc
     6541 catgtggaga agttgaggca gtttagaata aaaaggtaaa ggcatgagat tcttcctgga
     6601 ctcttaaaaa ggagttcatg gttggcctct tgggttaggc atagcccacc caatgggtgg
     6661 ggggtgcagg gctctctgcc agttccagca cccaggagtt tcacatgctc ttgtgggggg
     6721 ggggttagca ttggaaaaca ggcttctcct cttgcttttg aagtaaccct ggcctgacct
     6781 tgcaagagac tgcccttagg attttagctg agcgaagaga gaaagactaa gcaaaaatcc
     6841 cattggaagt accgagggag gaagagaaat ctcatgggaa tttcccagtt tcagttcatt
     6901 ctcggtgtag tgttttcttt tttaagtcaa tcgaggaggt cttgaaaatg tccaacagta
     6961 gcttttatca ctctggaaat cactgccttc atatggagaa ttaaattcag ggaccacgag
     7021 tttagtgtga atgtctgatc tgaaggggct gaggtttgtt tcttccttcc ttccttcctt
     7081 ccttccttcc ttccttcctt ccttccttcc tttgtattat gtttgtttgg ttttcttttg
     7141 cttcgaacgt ttcatttggt ctgagaaaag actgaatgtt aagtgtatgg ctgtgaggag
     7201 gctcggggcg gcctgtggcg gccgggccgg ctttctcaat agccactttt gatcagttgc
     7261 atttggtaca ggatttttga gtgacagtga aaattgttgt ctttggaaag cacaaaatta
     7321 acctggaaag gcgttccttc ggctcaggta gctacccaga atgcgtgtga tttgtgtgtc
     7381 tcagctgtct gcagagaaag cagctgccta aactactatt tacattccca gataactaga
     7441 gcaaacagct tttcacggcc ttgtgtattt gggggccctt ttctctgtcc tgaccccagg
     7501 catggatgaa attggaaatg atccctctgt gagaaatgaa tcggcatagc gtgttttcac
     7561 aactgtggag gaacagacgt agattcccaa gtcactgctg tgtgaggact gagtgagttt
     7621 ccagaaaaaa aaaaaatctg actgtcttaa gtccatgtta tcttgatttt taaattaata
     7681 gggggaaaga aaaaaaaccc acaaactgtc aaacaagttc tatgacaact aacaacattg
     7741 cactttctgt atatgaaatc aatatttaaa taacttattt ttctccattg ctattcttaa
     7801 acattgtaag tagctgtaat ataccaatac gttcttgcaa ttgcttcagc ccaagaaagc
     7861 tgtgtattgt tttaaaactg taaaaaaaaa attattgtga tgatccattt aaaaaaaaaa
     7921 aggaaggtgg acagaagggt tttcctgtgt atcaaaactg tctataataa tgtcatctat
     7981 gtacctaggg ggaaaagtaa ataaatttct tcagtcaaa
//
