LOCUS       NP_001100626             960 aa            linear   ROD 22-MAR-2023
DEFINITION  squamous cell carcinoma antigen recognized by T-cells 3 [Rattus
            norvegicus].
ACCESSION   NP_001100626 XP_001080462 XP_222279
VERSION     NP_001100626.1
DBSOURCE    REFSEQ: accession NM_001107156.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 960)
  AUTHORS   Long L, Thelen JP, Furgason M, Haj-Yahya M, Brik A, Cheng D, Peng J
            and Yao T.
  TITLE     The U4/U6 recycling factor SART3 has histone chaperone activity and
            associates with USP15 to regulate H2B deubiquitination
  JOURNAL   J Biol Chem 289 (13), 8916-8930 (2014)
   PUBMED   24526689
REFERENCE   2  (residues 1 to 960)
  AUTHORS   Zhang L, Li X and Zhao R.
  TITLE     Structural analyses of the pre-mRNA splicing machinery
  JOURNAL   Protein Sci 22 (6), 677-692 (2013)
   PUBMED   23592432
  REMARK    Review article
REFERENCE   3  (residues 1 to 960)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (residues 1 to 960)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (residues 1 to 960)
  AUTHORS   Liu Y, Timani K, Mantel C, Fan Y, Hangoc G, Cooper S, He JJ and
            Broxmeyer HE.
  TITLE     TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC
  JOURNAL   Blood 117 (21), 5643-5651 (2011)
   PUBMED   21447833
REFERENCE   6  (residues 1 to 960)
  AUTHORS   Song EJ, Werner SL, Neubauer J, Stegmeier F, Aspden J, Rio D,
            Harper JW, Elledge SJ, Kirschner MW and Rape M.
  TITLE     The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control
            reversible ubiquitination at the spliceosome
  JOURNAL   Genes Dev 24 (13), 1434-1447 (2010)
   PUBMED   20595234
REFERENCE   7  (residues 1 to 960)
  AUTHORS   Medenbach J, Schreiner S, Liu S, Luhrmann R and Bindereif A.
  TITLE     Human U4/U6 snRNP recycling factor p110: mutational analysis
            reveals the function of the tetratricopeptide repeat domain in
            recycling
  JOURNAL   Mol Cell Biol 24 (17), 7392-7401 (2004)
   PUBMED   15314151
REFERENCE   8  (residues 1 to 960)
  AUTHORS   Damianov A, Schreiner S and Bindereif A.
  TITLE     Recycling of the U12-type spliceosome requires p110, a component of
            the U6atac snRNP
  JOURNAL   Mol Cell Biol 24 (4), 1700-1708 (2004)
   PUBMED   14749385
REFERENCE   9  (residues 1 to 960)
  AUTHORS   Stanek D, Rader SD, Klingauf M and Neugebauer KM.
  TITLE     Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to
            Cajal bodies
  JOURNAL   J Cell Biol 160 (4), 505-516 (2003)
   PUBMED   12578909
REFERENCE   10 (residues 1 to 960)
  AUTHORS   Bell M, Schreiner S, Damianov A, Reddy R and Bindereif A.
  TITLE     p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling
            factor
  JOURNAL   EMBO J 21 (11), 2724-2735 (2002)
   PUBMED   12032085
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_222279.4, XP_001080462.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     Protein         1..960
                     /product="squamous cell carcinoma antigen recognized by
                     T-cells 3"
                     /calculated_mol_wt=109293
     Region          99..>459
                     /region_name="RNA14"
                     /note="Pre-mRNA 3'-end processing (cleavage and
                     polyadenylation) factor [RNA processing and modification];
                     COG5107"
                     /db_xref="CDD:227438"
     Region          703..776
                     /region_name="RRM1_SART3"
                     /note="RNA recognition motif 1 (RRM1) found in squamous
                     cell carcinoma antigen recognized by T-cells 3 (SART3) and
                     similar proteins; cd12391"
                     /db_xref="CDD:409825"
     Region          797..877
                     /region_name="RRM2_SART3"
                     /note="RNA recognition motif 2 (RRM2) found in squamous
                     cell carcinoma antigen recognized by T-cells 3 (SART3) and
                     similar proteins; cd12392"
                     /db_xref="CDD:409826"
     Region          875..933
                     /region_name="LSM_int_assoc"
                     /note="LSM-interacting associated unstructured; pfam16605"
                     /db_xref="CDD:465192"
     CDS             1..960
                     /gene="Sart3"
                     /coded_by="NM_001107156.1:15..2897"
                     /db_xref="GeneID:304582"
                     /db_xref="RGD:1311646"
ORIGIN      
        1 matatassas epevepqarp eaegeedeak pagvgrkvls saetakakgp erevhqegvs
       61 esdgdeedaa massaessag edeweydeee eknqleierl eeqlsingyd ynchvglirl
      121 lrlegelnkv rmarqkmsei fplteelwle wlhdeismav dgldrervye lferavkdyi
      181 cpniwleygq ysvggigqkg glekvrsvfe ralssvglhm tkglaiweay refesaivea
      241 arlervhslf rrqlaiplye meatfaeyee wseepipesv lqsyqkalgq lekykpyeea
      301 llqaeaprla eyqayidfem kvgdpariql iferalvenc lvpdlwirys qyldrqlkvk
      361 dlvlsvhsra vrncpwtval wsryllamer hgldhqmisa tfenalsagf iqatdyveiw
      421 qvyldylrrr vdfrqdsske leelrsmftr aleylqqeve erfsesgdps climqswarv
      481 earlcnnmqk arelwdsimt rgnakyanmw leyynlerah gdtqhcrkal hravqctsdy
      541 pehvcevllt mertegtled wdlaiqktet rlarvneqrm kaaekeaalv qqeeekaeqr
      601 kkvraekkal kkkktrgadk rkageddder ecgeeeeeqp skrrrmensl asgvasakee
      661 etklsgkclt idvappskqk ekaaslkrdm pkvahdsskd svtvfvsnlp ysieepevkl
      721 rplfeacgev vqirpifsnr gdfrgycyve fkeeksaqqa ldldrknveg rpmfvspcvd
      781 ksknpdfkmf rysttlekhk lfisglpfsc tkeelegick ahgtvkdlrl vtnragkpkg
      841 layveyenes qasqavlkmd gmtikenvik vaisnppqrk vpekpevrta pgapmvprqm
      901 ygargkgrtq lsllpralqr qgaapqaeng papglaatts vateapkmsn adfaklllrk
//
