LOCUS       NM_001004213            1860 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus store-operated calcium entry-associated
            regulatory factor (Saraf), mRNA.
ACCESSION   NM_001004213 XM_214364
VERSION     NM_001004213.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Yang,J., Li,S., Wang,Q. and Yang,D.
  TITLE     Transmembrane protein 66 attenuates neointimal hyperplasia after
            carotid artery injury by SOCE inactivation
  JOURNAL   Mol Med Rep 20 (2), 1436-1442 (2019)
   PUBMED   31173198
  REMARK    GeneRIF: TMEM66 attenuates neointimal hyperplasia after carotid
            artery injury by SOCE inactivation.
REFERENCE   2  (bases 1 to 1860)
  AUTHORS   Palty,R., Raveh,A., Kaminsky,I., Meller,R. and Reuveny,E.
  TITLE     SARAF inactivates the store operated calcium entry machinery to
            prevent excess calcium refilling
  JOURNAL   Cell 149 (2), 425-438 (2012)
   PUBMED   22464749
REFERENCE   3  (bases 1 to 1860)
  AUTHORS   Craft,C.M., Whitmore,D.H. and Wiechmann,A.F.
  TITLE     Cone arrestin identified by targeting expression of a functional
            family
  JOURNAL   J Biol Chem 269 (6), 4613-4619 (1994)
   PUBMED   8308033
  REMARK    Erratum:[J Biol Chem 1994 Jul 1;269(26):17756]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078979.1.
            
            On Sep 10, 2004 this sequence version replaced XM_214364.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078979.1, SRR8487227.44705.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00155337, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.2"
     gene            1..1860
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /note="store-operated calcium entry-associated regulatory
                     factor"
                     /db_xref="GeneID:290796"
                     /db_xref="RGD:1303011"
     exon            1..204
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1103
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /note="SOCE-associated regulatory factor; arrestin-E;
                     transmembrane protein 66"
                     /codon_start=1
                     /product="store-operated calcium entry-associated
                     regulatory factor precursor"
                     /protein_id="NP_001004213.1"
                     /db_xref="GeneID:290796"
                     /db_xref="RGD:1303011"
                     /translation="MAVAAVGRPRAVRCLLLLLLSFLLVAGPALCWKNPDRILLRDVE
                     ALTLYSDRYTTSRRLDPIPQLKCVGGTAGCDAYTPKVVQCQNKGWDGYDVQWECKTDL
                     DIAYKFGKTVVSCEGYDSSEDQYILRGSCGLEYNLDYTELGLSKLKESGKHQSFSDYY
                     HKLSSVDSCGLVTVAVLFVLAFVVYKLFLSDGQGSPPPYSEHPPYSQHSQRFAGTAGA
                     PPPGFKSDFTGPQSTSYGASSGFGSAFGGQSYASSGPGFWSGLGAGGLLGYLFGSNRA
                     ATPFSGSWYHPSYPSSYAGAWNSHAYSPLGGGAGRYSASSNTESRTRTTSGYGGTRRR
                     "
     exon            205..383
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            384..783
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            784..922
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1077
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1839
                     /gene="Saraf"
                     /gene_synonym="Tmem66"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccttaggt ggtggtgggt tttcggggtc gctgcgcagc agcggccaca cttccgccgc
       61 gggtctcggg ccgccgagcg ccgtcttcac ccagcaccat ggctgtggct gctgtcggcc
      121 gcccgagagc cgtgcgctgc ctgttgctgc ttctgctgtc cttcctgctg gtggccggcc
      181 ctgcgctgtg ctggaaaaac cctgaccgaa tactgttgcg ggatgtggaa gctctcaccc
      241 tctactctga ccgctacacc acctcccgga ggctggaccc catcccacag ttgaaatgcg
      301 ttggaggcac agcgggctgc gatgcctaca cccccaaagt ggtccagtgc cagaacaaag
      361 gctgggatgg ctacgatgta cagtgggaat gcaagaccga cttagatatt gcgtacaaat
      421 ttggcaaaac tgtggtgagc tgtgaaggct acgactcctc tgaagaccag tatatactca
      481 ggggttcctg tggcttggag tacaacttag attacacaga actgggcctg agcaaactga
      541 aggagtctgg gaaacaccaa agcttctctg attattatca caagctgtcc tcggtggact
      601 cctgtggctt ggttaccgtt gcagtactgt ttgttcttgc cttcgtggtt tacaagctgt
      661 tcctcagcga tggccagggc tcgcctccac cgtattctga gcacccgccg tactcacagc
      721 actctcagag gtttgccggc actgcaggag cgcctccccc gggctttaag tccgacttca
      781 caggaccaca gagcactagc tatggtgcaa gctctggctt cgggagtgcc tttggaggcc
      841 agagctacgc cagttcaggg ccgggcttct ggtctggcct gggcgctgga ggactgctcg
      901 gatatttgtt tggcagcaac agggcggcga cccctttctc aggctcgtgg taccatccat
      961 cctacccttc ttcctacgct ggcgcctgga acagtcatgc ctactcaccc ctgggtggag
     1021 gcgcagggcg ctattctgca tcctcgaata cagaatcgag gaccagaaca acgtcaggat
     1081 atggcggcac cagaagacgg taaaatagga agtgggaggc aagcactgga tgcaaagttt
     1141 ctgatttgtc atcaccatct ctttaacacc gggataatgg gaatatccaa aagtcgtgtg
     1201 gtgtttggtc cttgtatagc gttttgtgtc ctgttgtttg tggcccagag ttgatatgtg
     1261 acagaatact tacattttgt atgttaatgt aacatgcagt tcagagtgat ggctgctgtg
     1321 gagtgctgaa attgtagtgc ttgtttctaa ggcttctgta ccagaggcag cactaagaat
     1381 ggagcaccct cctcctgaga ctgagcccag acagcctaag ctgaggtggc tttggatgat
     1441 gactcattcc ctcgtagaaa cagcagtacc tcctctactg gatattacaa cattgtgctt
     1501 gctgttcttc aaacatttaa gccagcactg actactaatt atgcagattt gtgggttcca
     1561 attgcttgat ctttagagct cggacccctc ctcctgtgtt ggtcagcatc tggtgaatga
     1621 tcctgacctt ttgcaggaaa gggtagaaag taaatgactg ctcacagaag gcttgaaatt
     1681 gctagacttt tcagttttca ggtggtaaca ttcagatgct tcagtctctc agtagcaaaa
     1741 agcatggagt tctctgtgga gtcttaaact gtcagatgtt tttgtgacat tttgtttcag
     1801 ccttacatta atatgacaat aaattaaaac aaaacaaaaa aaaaaaaaaa aaaaaaaaaa
//
