LOCUS       NM_001033685             770 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus Sin3A associated protein 18 (Sap18), mRNA.
ACCESSION   NM_001033685 XM_214170
VERSION     NM_001033685.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 770)
  AUTHORS   Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M,
            Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R,
            Elela SA, Prinos P and Chabot B.
  TITLE     Proteins associated with the exon junction complex also control the
            alternative splicing of apoptotic regulators
  JOURNAL   Mol Cell Biol 32 (5), 954-967 (2012)
   PUBMED   22203037
REFERENCE   3  (bases 1 to 770)
  AUTHORS   Singh KK, Erkelenz S, Rattay S, Dehof AK, Hildebrandt A,
            Schulze-Osthoff K, Schaal H and Schwerk C.
  TITLE     Human SAP18 mediates assembly of a splicing regulatory multiprotein
            complex via its ubiquitin-like fold
  JOURNAL   RNA 16 (12), 2442-2454 (2010)
   PUBMED   20966198
REFERENCE   4  (bases 1 to 770)
  AUTHORS   Tange TO, Shibuya T, Jurica MS and Moore MJ.
  TITLE     Biochemical analysis of the EJC reveals two new factors and a
            stable tetrameric protein core
  JOURNAL   RNA 11 (12), 1869-1883 (2005)
   PUBMED   16314458
REFERENCE   5  (bases 1 to 770)
  AUTHORS   Schwerk C, Prasad J, Degenhardt K, Erdjument-Bromage H, White E,
            Tempst P, Kidd VJ, Manley JL, Lahti JM and Reinberg D.
  TITLE     ASAP, a novel protein complex involved in RNA processing and
            apoptosis
  JOURNAL   Mol Cell Biol 23 (8), 2981-2990 (2003)
   PUBMED   12665594
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY316441.1, BC104706.1, CK357541.1 and AW888346.1.
            
            On Dec 3, 2008 this sequence version replaced NM_001033685.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ234134.1, FQ237358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                DY316441.1         1-11
            12-698              BC104706.1         1-687
            699-754             CK357541.1         656-711
            755-770             AW888346.1         423-438
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..770
                     /gene="Sap18"
                     /note="Sin3A associated protein 18"
                     /db_xref="GeneID:290284"
                     /db_xref="RGD:1310388"
     exon            1..132
                     /gene="Sap18"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..522
                     /gene="Sap18"
                     /note="sin3-associated polypeptide, 18kDa;
                     Sin3A-associated protein, 18kDa; Sin3-associated
                     polypeptide 18"
                     /codon_start=1
                     /product="histone deacetylase complex subunit SAP18"
                     /protein_id="NP_001028857.2"
                     /db_xref="GeneID:290284"
                     /db_xref="RGD:1310388"
                     /translation="MLAAGVGGQGERLPGRRRKMAVESRVTQEEIKKEPEKPIDREKT
                     CPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKK
                     GTHFNFAIVFMDLKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPN
                     RAPPSSGRMRPY"
     exon            133..242
                     /gene="Sap18"
                     /inference="alignment:Splign:2.1.0"
     exon            243..365
                     /gene="Sap18"
                     /inference="alignment:Splign:2.1.0"
     exon            366..762
                     /gene="Sap18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcatgctcg ccgcaggggt cggaggtcag ggcgagcgtc tcccgggccg aaggaggaag
       61 atggcggtgg aatcgcgcgt tacccaggag gaaattaaga aggagccgga gaagccgatc
      121 gaccgcgaga agacctgccc gctgctgctg cgggtcttca ccaccaacaa cggccgccac
      181 caccgaatgg acgagttctc ccgcgggaac gtgccttcga gcgagctgca gatctacacc
      241 tggatggatg caaccttgaa agaactgact agtttagtaa aggaagtcta cccagaagcc
      301 agaaagaagg gcacgcactt caattttgca attgttttta tggatcttaa aagacctgga
      361 tatcgagtta aagagattgg cagcaccatg tctggcagga agggcactga tgactccatg
      421 accctgcagt cacagaagtt ccaaataggg gattatttgg acatagccat cacgcctcca
      481 aatcgggcac caccttcgtc agggaggatg agaccgtact gaattttatt gactttcttg
      541 aagttatttt tcagccagtt tgtaaaataa acttacttaa tcctttcctc ccccggactt
      601 tgccattaag cctttaaatg ttcaatgaat tgtaacattt atttaggaat tagaattgga
      661 tgtactttgg tatattaaag aaagtccata tgttttaagc ccttctgtaa aatatgaaga
      721 aaaaagtgct cttagcattc tgtataaagc agtactgtga aaaaaaaaaa
//
