LOCUS       NM_001399353            5326 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus sterile alpha motif domain containing 9 (Samd9),
            mRNA.
ACCESSION   NM_001399353 XM_575365
VERSION     NM_001399353.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5326)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   2  (bases 1 to 5326)
  AUTHORS   Topaz,O., Indelman,M., Chefetz,I., Geiger,D., Metzker,A.,
            Altschuler,Y., Choder,M., Bercovich,D., Uitto,J., Bergman,R.,
            Richard,G. and Sprecher,E.
  TITLE     A deleterious mutation in SAMD9 causes normophosphatemic familial
            tumoral calcinosis
  JOURNAL   Am J Hum Genet 79 (4), 759-764 (2006)
   PUBMED   16960814
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 6, 2022 this sequence version replaced XM_575365.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2719515.1,
                                           SRR26360172.234005.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676787 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               JAXUCZ010000004.1  32138729-32138958   c
            231-301             JAXUCZ010000004.1  32133345-32133415   c
            302-5326            JAXUCZ010000004.1  32119318-32124342   c
FEATURES             Location/Qualifiers
     source          1..5326
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q13"
     gene            1..5326
                     /gene="Samd9"
                     /gene_synonym="RGD1563091"
                     /note="sterile alpha motif domain containing 9"
                     /db_xref="GeneID:500011"
                     /db_xref="RGD:1563091"
     exon            1..230
                     /gene="Samd9"
                     /gene_synonym="RGD1563091"
                     /inference="alignment:Splign:2.1.0"
     exon            231..301
                     /gene="Samd9"
                     /gene_synonym="RGD1563091"
                     /inference="alignment:Splign:2.1.0"
     exon            302..5326
                     /gene="Samd9"
                     /gene_synonym="RGD1563091"
                     /inference="alignment:Splign:2.1.0"
     CDS             311..5092
                     /gene="Samd9"
                     /gene_synonym="RGD1563091"
                     /codon_start=1
                     /product="sterile alpha motif domain-containing protein 9"
                     /protein_id="NP_001386282.1"
                     /db_xref="GeneID:500011"
                     /db_xref="RGD:1563091"
                     /translation="MAETLNLPKNTDDWTKEDVNLWLESHRIDQKHREILMAQDVSGV
                     VLKWLNKKNLVEMGITHGPAIQIEELFKELQKTPKENLTKTCKKTKGRKNIPKTQTES
                     RETSNQNQRAEENSCKADTSAVSPEGNSQRTAASPEAKGSKSEKNDLVEDKAVQQDKQ
                     ASPGPTCIAYPFNEFSNPYRYKLHFILQPETGPLNLIDPVHEFKALTNTETATEEDIK
                     MKFSNEVFRFASACMNSRTNGTIHFGVQDKPQGRIVGMELTTVTKDALIDHFNLMIVQ
                     YFEVHQVQQAKKCIREPRFVEVLLPNSTPSNKFVIEVDIIPQYSECKEDFFQIKMHWH
                     KDETWQQIPKYSVFVRDGPKSKDIIGNKADFKAFKLDLKALADSRKEAEKKSKVKSDG
                     SNSQGQKLIDLLTGNKDLLDNSHYEWYILVTNKCHPDQTKHLDFLKEIKWFAVLEFDP
                     ESESNGVVKAFKGSRVANLHFPSLFIEEKPTVSEKISSLNLYQQPSWIFCNGRLDLES
                     DKYQPLDPISWQRERASEVRRLISFLTRDDIMPRGKFLVVFLLLSSVEDPRDPLIETF
                     CAFYQDLNGMENILCICVHPHIYQVWKDLLEVRLSSQQDELSSQSIFSLNLAEINGTI
                     LKLKSLTQSSKRFLPSVGSSTVLLKREEEIMTALEILCENECEGTLLEKDREKLFEFK
                     TSKEKDFYRGGKVSWWNFYFSSENYSSSFVKRDKYVKLEKKIQEWADSSQPVCAKIIH
                     LYHHPGCGGTTLAMHILWELRKKFRCAVLKNKTEDFSEIGEQVTNLITYGATNHQEYL
                     PVLLLVDDFEEQDNVYLLQTSIQTAVAKKHIRYEKPLVIILNCTRSQNPEKSAKNPDS
                     VALVQQLSDKEQRAFELKLTEIKEQHKNVEDFYSFMIMKTNFNKEYIENVVRNILKGQ
                     NVTTKEAKLFAFLALLNAFVPDTTISLSQCELFLGISNKKAYWGTEKFEDKMGTYSTI
                     LIKSEVIECGSYCGVRIIHHLIATLSLEELKRSYNLSKSKIVMDMLTENLFYDTGIGK
                     SKFYQDMQTLLITRQRNEHERETGNWFSPFIEALHKDEGNDAVKAVLHEATRRFDPNA
                     FICQALARHFYLKEKDFESALLWAKQARKIAPNNSYISDTLGQVYKSKLRWWVEDNIK
                     NGIISVDELTELLDLAKHASEAFKDSQQQTEDREYEGKESVYQKSKRRYDTYNIAGYQ
                     GEIEVGLYTIQILKLLPFFNSKNELSRQVMINFISGNCDIPGDLNEFKSVLKNFISYL
                     TNLQSSLKKSFDFFDDYFVLLKPRNNIEQYEEAKSRRKVAMYFKKYVEIFGPLAELQN
                     QNFRSKLSLPLQVERTRRSLEALKADKFSGLLEYLIKSPKDTVSSMEDIVNKYTFLLE
                     QCAIKIQQKEKQNFILASIILSCINPISKFVKPIKKLKEQLREILQPIGLTYQFSEPY
                     FLASLLFWPENQQLDQDSKQMEKYAQALEKSFRGQYKRLYRTKQPIAYFFLGKGNSRN
                     RLIHKGKIDENFENLSDINSWWHTGKVWEEKKVQDLLVRLPGRAENNCLYIEYGINEK
                     ITIPIKPTHFGQLRSGRSIEKVSFYLGFSIGGLLAYDIKIV"
ORIGIN      
        1 agttttcaag tcattagccg caccctggtg tttcccagcc tatttgtgct ggtaccaagg
       61 tagacaagca gtctggttta gcttacagca agactaaatg aagttatttt tccctgacat
      121 cttaggagga agagaataca gacaccagac attttcttca tcaaaatgga cagtgttttc
      181 tttttttcct ttaaaatttt cttttacata gaagaaattt gaaaatttgg tgagagcatc
      241 agtgacctct gtgatcatca accttacttg agggagttca ttgtgtctcc aggcagtttg
      301 gctaatcaga atggcagaga cactcaacct tccaaaaaac acagatgact ggacaaaaga
      361 ggatgtaaac ctgtggctag aaagtcatag gattgaccaa aagcacaggg aaatcttgat
      421 ggcacaagat gtgagtggag tagtcttgaa gtggttaaat aaaaaaaatc ttgttgaaat
      481 gggcataacc catgggccag ctatccaaat agaagagcta ttcaaagaat tgcagaaaac
      541 acccaaagaa aatcttacta agacatgtaa gaagacaaaa ggcagaaaaa atatccctaa
      601 aacccagaca gaaagtagag agacttcaaa tcaaaaccag agagctgaag agaactcatg
      661 caaggctgac acctctgcag tgagtccaga aggaaactca caaaggactg cagcaagtcc
      721 agaggctaaa ggttctaaat cagaaaaaaa tgacctagta gaagataaag cagtccaaca
      781 ggataagcag gcatctccag gaccaacgtg cattgcatat cctttcaatg agttcagtaa
      841 tccatatcgt tacaaattac atttcatcct acagcctgaa acagggccac tcaatctcat
      901 tgacccagta catgagttca aagccttaac aaacacagag acagccacag aggaggacat
      961 aaagatgaaa tttagcaacg aagtcttccg atttgcttca gcttgtatga actcacgtac
     1021 taatggcacc attcattttg gagtccaaga caaaccccaa ggaaggattg ttggcatgga
     1081 gctcaccacc gtcactaaag atgccctcat tgaccacttc aatctgatga tagtccagta
     1141 ttttgaggtc catcaagtcc aacaagcaaa gaagtgcatt cgagagccaa gatttgtgga
     1201 agttttactg ccaaatagta ctccatctaa taaatttgtt attgaggtgg atatcattcc
     1261 acaatattca gaatgcaaag aagatttctt ccaaataaaa atgcattggc ataaggatga
     1321 aacatggcaa caaattccaa aatactcggt ctttgtgaga gatggtccga aaagtaagga
     1381 catcataggg aataaagctg atttcaaagc ttttaagtta gacctaaaag cactggcaga
     1441 ctctaggaaa gaagcagaaa aaaaatccaa agtaaaatca gatggaagca acagtcaggg
     1501 gcaaaagcta attgacctgt tgacaggaaa taaggatctg ctagataact cacactatga
     1561 atggtacatt cttgtaacaa ataaatgtca tccagatcaa accaaacacc tagatttcct
     1621 gaaggaaatt aaatggtttg ctgtactaga gtttgatcct gagtctgaga gcaatggtgt
     1681 ggtcaaggct ttcaaaggaa gccgagtagc aaacctccac tttccaagcc tatttataga
     1741 agaaaaaccc acagtaagtg aaaagatttc cagtctgaat ctttatcagc aacctagctg
     1801 gattttctgc aatggcaggt tagacctaga gagtgacaaa taccaaccct tagatccgat
     1861 atcctggcaa agagagagag cttctgaagt cagaagactg atttcatttc ttacacgtga
     1921 tgacataatg ccaagaggga aatttctggt agtgttttta ttactgtcct ctgtggaaga
     1981 cccaagagat ccccttattg agactttctg tgctttctat caagatctta atggaatgga
     2041 aaatatactg tgcatttgtg tacacccaca catatatcag gtatggaaag acctacttga
     2101 agtaagatta tcaagccagc aagatgaatt atcaagccaa agcattttta gtttaaatct
     2161 tgcagagata aatggcacta ttcttaaatt aaaatcttta actcagtctt cgaagcgatt
     2221 cttgccatct gttggctcat ctactgtcct tctgaaaagg gaagaagaaa ttatgactgc
     2281 cttggaaatc ctctgtgaaa atgaatgcga aggtacactc ttggagaaag atagagagaa
     2341 attatttgaa tttaagacat ccaaagagaa agacttctac aggggtggca aagtgtcttg
     2401 gtggaacttc tacttttctt ctgaaaacta ttcttcatca tttgtcaaaa gggataaata
     2461 tgtaaaactt gaaaaaaaga ttcaagaatg ggcagattct tctcagccag tatgtgcaaa
     2521 aattattcac ctctatcatc atccaggctg tggagggact actttagcaa tgcacatcct
     2581 ctgggaacta aggaagaaat ttagatgtgc tgtgctgaaa aataagacag aggacttttc
     2641 agaaattgga gaacaggtaa caaatttaat cacgtatgga gcaacaaacc atcaggagta
     2701 tttacctgtg ctgctccttg ttgatgattt tgaagagcaa gacaacgtct accttcttca
     2761 gacctccatc caaacggctg tggctaagaa acacattcga tatgagaagc ctctagtaat
     2821 cattctcaat tgtacaaggt cacaaaatcc tgagaaaagt gcaaagaacc cagacagtgt
     2881 tgccctagta caacaactct ctgacaaaga acaaagagca tttgagttga agctgacaga
     2941 aatcaaagaa cagcataaaa acgttgaaga tttttattct ttcatgatca tgaaaaccaa
     3001 ctttaacaaa gagtacatag aaaatgtggt caggaacatt ctgaaagggc aaaatgtcac
     3061 caccaaagaa gcaaagctct ttgctttcct ggctctcctt aatgcatttg tacctgacac
     3121 taccatttct ctttcacagt gtgagctttt cctaggaatc tcaaacaaga aggcttactg
     3181 ggggacagaa aagtttgaag ataagatggg tacttactcc acaattctaa tcaaatcaga
     3241 ggtgatcgaa tgtgggagct actgtggagt gcgcatcatt caccatttga ttgccactct
     3301 ctccctggag gaattgaaga gaagctacaa tttgagcaaa agtaaaattg tgatggatat
     3361 gttaacagaa aacttgttct atgacactgg tataggaaaa agcaaatttt accaagacat
     3421 gcaaacattg ctgatcacaa gacagcgcaa tgaacatgaa cgtgagacag gaaactggtt
     3481 ttctccattc attgaagcct tacataaaga tgaaggaaat gatgcagtga aagctgtatt
     3541 acatgaagct acacgtaggt tcgaccccaa tgcattcatc tgccaagctt tagccagaca
     3601 tttctacctt aaagagaagg actttgaaag tgctctactt tgggcaaaac aagcaagaaa
     3661 aatagcgcct aataattctt acatctcaga tacactaggt caagtctaca aaagtaaact
     3721 aagatggtgg gtagaggata atataaaaaa tgggattatc tcggtggatg agctaactga
     3781 acttttagat ttagcgaagc atgcatcaga ggctttcaaa gactctcaac agcaaactga
     3841 agaccgagaa tatgaaggga aagaaagcgt gtatcagaag tcaaaaagga ggtatgacac
     3901 ttacaacata gctggttatc aaggagagat agaagttggc ctctatacca tccagatcct
     3961 caaacttctt ccttttttta acagcaaaaa tgaactatct cgacaagtta tgatcaactt
     4021 tatatcagga aattgtgata taccagggga tctaaatgaa tttaagtcag tattgaagaa
     4081 ttttatttct tatctaacta acctgcagtc ttctttgaag aaatcctttg atttttttga
     4141 tgattacttt gtccttctaa aacccagaaa caatatagag caatatgaag aggctaaaag
     4201 tcggagaaag gtggccatgt actttaagaa gtatgtagaa atatttggcc ccttggcaga
     4261 attacaaaat caaaatttta gatcaaagct cagtctacca ctacaagtag aaaggactcg
     4321 gagaagccta gaagctttaa aagcagacaa gttttctgga ctcttggaat accttatcaa
     4381 aagtccaaaa gatacggtga gctccatgga agatattgtg aataaatata ctttccttct
     4441 tgagcaatgt gctatcaaaa tccaacaaaa ggaaaagcaa aattttatct tggccagcat
     4501 cattctctct tgtattaacc ctatctccaa gttcgtgaag cccattaaaa aactgaaaga
     4561 acagcttcga gagatcctgc aaccaatagg actgacttac cagttttcag aaccttattt
     4621 tctagcctct cttttattct ggccagaaaa ccaacaacta gatcaagatt ctaaacaaat
     4681 ggaaaagtat gctcaagcac tggagaaatc tttccggggg cagtataaac gtttgtatcg
     4741 cacaaagcaa ccaattgcat atttctttct tgggaaaggc aacagtagga atagactgat
     4801 tcacaaagga aaaattgatg aaaattttga aaatttatca gatattaatt cctggtggca
     4861 tacaggaaaa gtatgggaag agaaaaaggt ccaggatctt ttagttcgtt taccgggacg
     4921 agctgaaaac aactgtttat acatagagta tgggatcaat gaaaaaatca caataccaat
     4981 taaacccact cattttggtc agcttagaag tgggaggagc atagaaaagg tgtcttttta
     5041 cctaggattt tccattggcg gccttcttgc ttatgacatt aaaattgttt aagaccttga
     5101 gtttctcaag agatatggtt ttaatatcaa cttttttctt taatttactt atagatacca
     5161 ctcttaataa ttctgtgtag tggggaaagg aagagtagta gaagaaaaac aagactgagc
     5221 ctcacttggg tatttctgtg catagggttc tttttactct tccctctgtg ttggcaagaa
     5281 attcttctaa aacttctgca aaataaaatc ggacaaaaat atgcaa
//
