LOCUS       NM_001303144            3236 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus scaffold attachment factor B2 (Safb2), mRNA.
ACCESSION   NM_001303144 XM_002727153 XM_002730092
VERSION     NM_001303144.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3236)
  AUTHORS   Jiang,S., Katz,T.A., Garee,J.P., DeMayo,F.J., Lee,A.V. and
            Oesterreich,S.
  TITLE     Scaffold attachment factor B2 (SAFB2)-null mice reveal
            non-redundant functions of SAFB2 compared with its paralog, SAFB1
  JOURNAL   Dis Model Mech 8 (9), 1121-1127 (2015)
   PUBMED   26092125
REFERENCE   2  (bases 1 to 3236)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 3236)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 3236)
  AUTHORS   Tsianou,D., Nikolakaki,E., Tzitzira,A., Bonanou,S., Giannakouros,T.
            and Georgatsou,E.
  TITLE     The enzymatic activity of SR protein kinases 1 and 1a is negatively
            affected by interaction with scaffold attachment factors B1 and 2
  JOURNAL   FEBS J 276 (18), 5212-5227 (2009)
   PUBMED   19674106
REFERENCE   5  (bases 1 to 3236)
  AUTHORS   Kang,D., Oh,S., Ahn,S.M., Lee,B.H. and Moon,M.H.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Dec 19, 2014 this sequence version replaced
            XM_002730092.4, XM_002727153.4.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data because no single transcript from the reference strain was
            available for the full length of the gene. The extent of this
            transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ221088.1, SRR26643295.34318.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-262               JAXUCZ010000009.1  1503881-1504142     c
            263-350             JAXUCZ010000009.1  1502627-1502714     c
            351-415             JAXUCZ010000009.1  1499519-1499583     c
            416-619             JAXUCZ010000009.1  1499239-1499442     c
            620-682             JAXUCZ010000009.1  1498264-1498326     c
            683-710             JAXUCZ010000009.1  1497274-1497301     c
            711-1371            JAXUCZ010000009.1  1495759-1496419     c
            1372-1421           JAXUCZ010000009.1  1495380-1495429     c
            1422-1522           JAXUCZ010000009.1  1494764-1494864     c
            1523-1672           JAXUCZ010000009.1  1491870-1492019     c
            1673-1782           JAXUCZ010000009.1  1491680-1491789     c
            1783-1910           JAXUCZ010000009.1  1489832-1489959     c
            1911-2002           JAXUCZ010000009.1  1488494-1488585     c
            2003-2139           JAXUCZ010000009.1  1487010-1487146     c
            2140-2430           JAXUCZ010000009.1  1486486-1486776     c
            2431-2568           JAXUCZ010000009.1  1486006-1486143     c
            2569-2611           JAXUCZ010000009.1  1485341-1485383     c
            2612-2742           JAXUCZ010000009.1  1484645-1484775     c
            2743-2855           JAXUCZ010000009.1  1483614-1483726     c
            2856-2922           JAXUCZ010000009.1  1483467-1483533     c
            2923-3236           JAXUCZ010000009.1  1482985-1483298     c
FEATURES             Location/Qualifiers
     source          1..3236
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3236
                     /gene="Safb2"
                     /note="scaffold attachment factor B2"
                     /db_xref="GeneID:301126"
                     /db_xref="RGD:1588577"
     exon            1..262
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..3067
                     /gene="Safb2"
                     /codon_start=1
                     /product="scaffold attachment factor B2"
                     /protein_id="NP_001290073.1"
                     /db_xref="GeneID:301126"
                     /db_xref="RGD:1588577"
                     /translation="MAEPVTGSGDPAFSPVASDSGMRRLSDLRVIDLRAELKKRNLDT
                     GGNKSVLMERLKKAFKEEGQEPEEVGISWGAVSKRAIKRNTKGAKMEEEGGEDTGLEE
                     DSRDGQDETVILQSSQDRDTVDTGVPDGMEAQDLSVPCLGKADTDKQSLDAFDDSKEY
                     VAAQLGQLPAQLLKHAVNEDVFKNTLEASMSDLKVTMAGEEAPLEPENEKILDILGET
                     CKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEEEQEEE
                     QEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPAEAPGGGGGTQHWRKRKRRR
                     KHQAEAEALGTGGGTWMNREPVGLEEPVEQSSTAAQLPEATSQELVRAPTAAPSPEPR
                     DSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSFVKEEQDIKPVIKDEKGRASCSS
                     GRNLWVSGLSSSTRAADLKSLFSKHGKVIGAKVVTNARSPGARCYGFVTMSMSDEATK
                     CINHLHRTELHGRMISVEKAKNEPSEKKSADRRACDQKEKVPGPDRPHPVKIKMEKTV
                     IKKEEKLERKEEKGPEDIKKEKDQDELPPGTASHSRVTKSGSRCTERTVVMDKSKGEP
                     VISVKATSRSKDRSSKSQDRKSEGREKRDILSFDKIKEQRERERQRQREREIRETERR
                     REREQREREQRLDAFQERREKARLQRERLQLQCQRQRLERERLERERLERERMRVERE
                     RRKEQQRIMREREELRRQQEQLRAEQERRALRRAYNLDARRDDGYWPEGKRAAMEDRY
                     RDFPRPDHRFHDFDHRERGHYQEHVIDRRDGSRPRMEERDGPYYPDDQHSHGRPLEHH
                     GWDARDGWHGYSSDKKLNEGLGLPPPPRVSREWAEHSSQLEEQQVPVWHNAVDTNMTG
                     HEHIRWRGAERGLTGPGHGHVAAGRGGMAGQGSFAHGEHSQGHIMPSGRLEGGGVASQ
                     DQGGRIPNSHPHPHFTRRY"
     exon            263..350
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            351..415
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            416..619
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            620..682
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            683..710
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            711..1371
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1421
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1522
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1672
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1782
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1910
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2002
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2139
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2140..2430
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2568
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2569..2611
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2742
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2855
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..2922
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
     exon            2923..3236
                     /gene="Safb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcgcca ttttgtactc agagcctctg cagccggggg cagcgagtgt aggaggttcc
       61 ggagcggggt tgggaagtca cggaagcgag aatggcagaa cctgtgaccg ggtcgggcga
      121 cccggctttt agtccggtcg cttcggatag tgggatgcgg cggctcagcg acctgcgggt
      181 gatcgacctg agggcggagc tgaagaagcg gaacctggat acaggaggca acaagagtgt
      241 gttgatggag cggctgaaga aggcatttaa agaggaagga caagaacctg aggaagtcgg
      301 tatcagttgg ggagctgtaa gcaagagggc tataaagaga aacaccaaag gggccaagat
      361 ggaggaggag ggcggtgagg acaccggcct ggaggaagat tccagagatg ggcaggatga
      421 gactgtgatt cttcagagtt cacaagacag ggacactgtg gatacaggtg tgccagatgg
      481 gatggaggct caggacctca gtgtgccctg cctggggaag gccgacaccg acaaacagtc
      541 tcttgatgcc tttgatgaca gtaaagagta cgtggccgcg cagctgggac agcttccagc
      601 tcagctcctg aagcatgctg tgaatgagga tgtcttcaag aacactctgg aagcttccat
      661 gtcagacctt aaagtaacta tggctggtga agaagccccg ttggaaccag aaaatgagaa
      721 aatactcgac attttggggg aaacttgtaa atctgagcca gtaaaagaag aaggttcgga
      781 gctggagcag ccctttgccc aggccacgag tagcgtgggg ccagacagga agctggcgga
      841 ggaagaggac ctatttgaga gctgcggcca cccggaagag gaagaagaag aggaggaaga
      901 agaggagcag gaagaggagc aggaggagga gggagattta gctttggcca gcagcagcaa
      961 gtctgagtct tcaagcactc gatgtcagtg gagcgaggca gacgccctgt tagcagtagt
     1021 gaaaagggag ccggcagagg cgcctggtgg aggcggaggt actcagcact ggcggaagcg
     1081 aaagcgaagg cggaagcatc aggcagaggc agaagctctg ggcacgggtg gaggtacctg
     1141 gatgaaccgc gagcctgtag ggctagagga gccagttgaa cagagtagca cggctgccca
     1201 gctcccggag gccaccagcc aggagctggt gcgagcgccc acggcagccc cgagccctga
     1261 gccccgagat agcaaagacg acgtgaagaa gtttgctttt gacgcttgta atgacgtccc
     1321 tgcggctcct aaagagtcct cagccagtga gggtgctgat cagaaaatga gctttgttaa
     1381 ggaagaacag gatataaagc cagtcattaa agacgagaaa ggccgtgcca gctgtagctc
     1441 aggaaggaac ctgtgggtca gtggactgtc ctccagcaca cgtgctgctg atctcaagag
     1501 cctcttcagc aagcatggga aggtcattgg agccaaggtg gttaccaatg cccgcagtcc
     1561 tggagctcga tgctatggat ttgtgaccat gtccatgtca gatgaggcca ccaaatgcat
     1621 caaccacctg cacagaacag aactgcatgg aaggatgatc tctgtggaga aggccaaaaa
     1681 tgagccctct gagaagaagt cagcagacag gagagcttgt gaccaaaagg agaaggtgcc
     1741 agggccagac aggcctcacc ctgtgaagat caagatggag aaaactgtga tcaaaaagga
     1801 agagaaactg gaaagaaagg aagagaaagg gccagaggac attaagaagg agaaggatca
     1861 agatgagctt ccaccaggaa ccgccagtca ttctcgagta accaaatcag gaagcagatg
     1921 cacggagcgt acagtcgtga tggacaagtc caagggcgag cccgtcatca gtgtgaaggc
     1981 cacaagcagg tcaaaggaca gaagctccaa aagtcaagac cgaaagtcag agggcaggga
     2041 gaagagagac atattgtcat ttgacaagat caaggagcag cgggagcggg agcgccagag
     2101 gcagagggag cgtgaaatcc gggagaccga gcggcgacgg gagcgggagc agcgagagcg
     2161 ggagcagcgt ctggatgcct tccaggagcg gcgggagaag gctcgtttgc agcgagaacg
     2221 gctgcagctc caatgccagc ggcagcgtct agaaagggag cggctggaga gggagagact
     2281 ggagagggag cgcatgcgag tggagcgtga aaggcgcaag gaacagcagc gcattatgcg
     2341 tgagcgtgag gagctgcgac ggcagcaaga gcagctgcgg gctgagcagg aacggcgagc
     2401 attgcgcaga gcctacaacc tggatgctag gagagatgat ggctactggc cagaagggaa
     2461 gcgtgcagcc atggaagaca gatatcgaga ctttccaagg ccagatcacc gtttccatga
     2521 cttcgatcac cgggaacggg gtcattacca ggagcatgtt atagacagga gggatgggtc
     2581 cagacccaga atggaagagc gggatgggcc gtactaccca gatgaccagc acagccatgg
     2641 aaggcctctg gagcaccatg gttgggacgc ccgagacggc tggcatggct acagctctga
     2701 caagaagttg aatgaaggcc tagggctacc ccctcccccc agggtcagcc gagaatgggc
     2761 agagcacagc tcacagttgg aggagcagca ggttcctgtc tggcacaacg ctgtggacac
     2821 aaacatgacg ggccatgaac acatacggtg gcgaggtgct gagcggggcc ttacaggacc
     2881 tgggcatggg catgtggcag caggccgggg tggcatggct gggcaaggca gctttgcaca
     2941 cggtgaacat tcccagggcc atattatgcc tagtggtaga ctggaaggtg gtggcgtggc
     3001 cagccaggac cagggtggcc gaattcccaa ctcccaccct cacccccact tcacccgccg
     3061 ctactgaacc ctgctctgga ccaaattctg ctgctgcaag taggcagaaa ctgcagcccc
     3121 agccacctcc tacttgtggc actgctagca gtcacgggtt ctgccaaccg ttgatgtgaa
     3181 ctcagtctcc tggtgttttt aataaacaca gtcctattct gccgtttgta agacaa
//
