LOCUS       NP_071789                940 aa            linear   ROD 30-MAR-2024
DEFINITION  scaffold attachment factor B1 [Rattus norvegicus].
ACCESSION   NP_071789
VERSION     NP_071789.2
DBSOURCE    REFSEQ: accession NM_022394.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 940)
  AUTHORS   Hashimoto,T., Kawata,M., Hirahara,Y., Nishi,M., Satoshi,I. and
            Matsuda,K.I.
  TITLE     Scaffold attachment factor B: distribution and interaction with
            ERalpha in the rat brain
  JOURNAL   Histochem Cell Biol 153 (5), 323-338 (2020)
   PUBMED   32086573
  REMARK    GeneRIF: Scaffold attachment factor B: distribution and interaction
            with ERalpha in the rat brain.
REFERENCE   2  (residues 1 to 940)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (residues 1 to 940)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (residues 1 to 940)
  AUTHORS   Heinrich,B., Zhang,Z., Raitskin,O., Hiller,M., Benderska,N.,
            Hartmann,A.M., Bracco,L., Elliott,D., Ben-Ari,S., Soreq,H.,
            Sperling,J., Sperling,R. and Stamm,S.
  TITLE     Heterogeneous nuclear ribonucleoprotein G regulates splice site
            selection by binding to CC(A/C)-rich regions in pre-mRNA
  JOURNAL   J Biol Chem 284 (21), 14303-14315 (2009)
   PUBMED   19282290
REFERENCE   5  (residues 1 to 940)
  AUTHORS   Omura,Y., Nishio,Y., Takemoto,T., Ikeuchi,C., Sekine,O., Morino,K.,
            Maeno,Y., Obata,T., Ugi,S., Maegawa,H., Kimura,H. and Kashiwagi,A.
  TITLE     SAFB1, an RBMX-binding protein, is a newly identified regulator of
            hepatic SREBP-1c gene
  JOURNAL   BMB Rep 42 (4), 232-237 (2009)
   PUBMED   19403048
REFERENCE   6  (residues 1 to 940)
  AUTHORS   Traweger,A., Fuchs,R., Krizbai,I.A., Weiger,T.M., Bauer,H.C. and
            Bauer,H.
  TITLE     The tight junction protein ZO-2 localizes to the nucleus and
            interacts with the heterogeneous nuclear ribonucleoprotein scaffold
            attachment factor-B
  JOURNAL   J Biol Chem 278 (4), 2692-2700 (2003)
   PUBMED   12403786
  REMARK    GeneRIF: nuclear tight junction protein ZO-2 directly interacts
            with the DNA-binding protein scaffold attachment factor-B
REFERENCE   7  (residues 1 to 940)
  AUTHORS   Nikolakaki,E., Kohen,R., Hartmann,A.M., Stamm,S., Georgatsou,E. and
            Giannakouros,T.
  TITLE     Cloning and characterization of an alternatively spliced form of SR
            protein kinase 1 that interacts specifically with scaffold
            attachment factor-B
  JOURNAL   J Biol Chem 276 (43), 40175-40182 (2001)
   PUBMED   11509566
REFERENCE   8  (residues 1 to 940)
  AUTHORS   Stoss,O., Olbrich,M., Hartmann,A.M., Konig,H., Memmott,J.,
            Andreadis,A. and Stamm,S.
  TITLE     The STAR/GSG family protein rSLM-2 regulates the selection of
            alternative splice sites
  JOURNAL   J Biol Chem 276 (12), 8665-8673 (2001)
   PUBMED   11118435
REFERENCE   9  (residues 1 to 940)
  AUTHORS   Hartmann,A.M., Nayler,O., Schwaiger,F.W., Obermeier,A. and Stamm,S.
  TITLE     The interaction and colocalization of Sam68 with the
            splicing-associated factor YT521-B in nuclear dots is regulated by
            the Src family kinase p59(fyn)
  JOURNAL   Mol Biol Cell 10 (11), 3909-3926 (1999)
   PUBMED   10564280
REFERENCE   10 (residues 1 to 940)
  AUTHORS   Nayler,O., Stratling,W., Bourquin,J.P., Stagljar,I., Lindemann,L.,
            Jasper,H., Hartmann,A.M., Fackelmayer,F.O., Ullrich,A. and Stamm,S.
  TITLE     SAF-B protein couples transcription and pre-mRNA splicing to
            SAR/MAR elements
  JOURNAL   Nucleic Acids Res 26 (15), 3542-3549 (1998)
   PUBMED   9671816
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Apr 30, 2015 this sequence version replaced NP_071789.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF056324.1, SRR26643293.48577.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     Protein         1..940
                     /product="scaffold attachment factor B1"
                     /note="SAF-B; SAF-B1"
                     /calculated_mol_wt=105386
     Region          31..65
                     /region_name="SAP"
                     /note="SAP domain; pfam02037"
                     /db_xref="CDD:460424"
     Region          32..>183
                     /region_name="PLN03124"
                     /note="poly [ADP-ribose] polymerase; Provisional"
                     /db_xref="CDD:215591"
     Region          428..503
                     /region_name="RRM_SAFB1_SAFB2"
                     /note="RNA recognition motif (RRM) found in scaffold
                     attachment factor B1 (SAFB1), scaffold attachment factor
                     B2 (SAFB2), and similar proteins; cd12679"
                     /db_xref="CDD:410080"
     CDS             1..940
                     /gene="Safb"
                     /coded_by="NM_022394.2:95..2917"
                     /db_xref="GeneID:64196"
                     /db_xref="RGD:620613"
ORIGIN      
        1 maetlsglgd sgaasaaavs saasetgtrr lsdlrvidlr aelrkrnlds sgnksvlmer
       61 lkkaieeegg npdeievise gnkkmpkrps kgkkpedegv edngleensg dgqedvetsl
      121 enlqdmdmmd isvldeadid ngsvadcvee eeeatlpegl gdstelvegd skglpeqlqe
      181 haiddkeain nvdtsssdft ilqemeeasl epenekildi lgetcksepv keegseleqp
      241 faqatssvgp drklaeeedl fescghpeee eeeeeeeeqe eeqeeegdla lasssksess
      301 strcqwsead allavvkrep aeapgggtgm drepvgleep veqsstaaql pettsqelvr
      361 aptaapspep rdskddvkkf afdacndvpa apkessaseg adqkmssved dsdtkrlsre
      421 ekgrsscgrn fwvsglsstt ratdlknlfs rygkvvgakv vtnarspgar cygfvtmsta
      481 eeatkcinhl hktelhgkmi svekaksepa gkrvpdrrdg dskkektsts drsanlkree
      541 kgdrkddakk tddgsteksk daddqkpgps ersrttksgs rgtertvvmd kskgvpvisv
      601 ktsgskeras ksqdrksvsr ekrsvvsfdk vkesrksrds esrrererer sereqrlqaq
      661 wereererle iarerlafhr hrlerermer erlerermhv eqerrreqer ihrereelrr
      721 qqelryeqer rpavrrpyev dgrrddaywp eakraalddr yhsdfsrqdr fhdfdhrdrg
      781 rypnhsvdrr egsrsmmgdr egqhyperhg gperhgrdsr dgwgygsnkr lsegrglppp
      841 prrdwgehgr rleddrawqg tadggmmerd hkrwqggers msghsgpghm mnrggmsgrg
      901 sfapggasrg hviprggmqa gfggqsrgsr psdarftrry
//
