LOCUS       NM_001108557            1036 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus S100 calcium binding protein A16 (S100a16), mRNA.
ACCESSION   NM_001108557 XM_001075704 XM_342291
VERSION     NM_001108557.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1036)
  AUTHORS   Zhang R, Su D, Zhu W, Huang Q, Liu M, Xue Y, Zhang Y, li D, Zhao A
            and Liu Y.
  TITLE     Estrogen suppresses adipogenesis by inhibiting S100A16 expression
  JOURNAL   J Mol Endocrinol 52 (3), 235-244 (2014)
   PUBMED   24501224
  REMARK    GeneRIF: Estrogen suppressed adipogenesis by inhibiting S100A16
            expression.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1036)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1036)
  AUTHORS   Zhang R, Zhu W, Du X, Xin J, Xue Y, Zhang Y, Li D and Liu Y.
  TITLE     S100A16 mediation of weight gain attenuation induced by dietary
            calcium
  JOURNAL   Metabolism 61 (2), 157-163 (2012)
   PUBMED   21871643
  REMARK    GeneRIF: High-calcium diets may lead to nuclear exclusion of
            S100A16, which results in the inhibition of adipogenesis and
            enhanced insulin sensitivity.
REFERENCE   4  (bases 1 to 1036)
  AUTHORS   Fornander L, Ghafouri B, Kihlstrom E, Akerlind B, Schon T, Tagesson
            C and Lindahl M.
  TITLE     Innate immunity proteins and a new truncated form of SPLUNC1 in
            nasopharyngeal aspirates from infants with respiratory syncytial
            virus infection
  JOURNAL   Proteomics Clin Appl 5 (9-10), 513-522 (2011)
   PUBMED   21805676
REFERENCE   5  (bases 1 to 1036)
  AUTHORS   Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE and
            Yates JR.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 1036)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 1036)
  AUTHORS   Sturchler E, Cox JA, Durussel I, Weibel M and Heizmann CW.
  TITLE     S100A16, a novel calcium-binding protein of the EF-hand superfamily
  JOURNAL   J Biol Chem 281 (50), 38905-38917 (2006)
   PUBMED   17030513
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158598.1.
            
            On Jan 27, 2008 this sequence version replaced NM_001108557.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158598.1, CK472648.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1036
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1036
                     /gene="S100a16"
                     /note="S100 calcium binding protein A16"
                     /db_xref="GeneID:361991"
                     /db_xref="RGD:1306770"
     exon            1..43
                     /gene="S100a16"
                     /inference="alignment:Splign:2.1.0"
     exon            44..222
                     /gene="S100a16"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..441
                     /gene="S100a16"
                     /codon_start=1
                     /product="protein S100-A16"
                     /protein_id="NP_001102027.1"
                     /db_xref="GeneID:361991"
                     /db_xref="RGD:1306770"
                     /translation="MADCYTELEKALVVLVENFYKYVSKHSLVKNKISKSSFRKMLQK
                     ELNHMLTDTGNRKAADKLIQNLDANHDGRICFDEYWTMIGGITSPMANLIREQECQQE
                     CQQESQQESQQESQQEQQGSS"
     exon            223..1013
                     /gene="S100a16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctcagag ccctgctgga ggaggttgac tcggaggaga caggcccaga gaggagctga
       61 ggcagtgaga tggccgactg ctatacagag ctggagaagg cacttgttgt cctggtagaa
      121 aacttttata aatatgtatc caagcacagc ctggtcaaga acaagatcag caagtccagt
      181 ttccgaaaga tgctccagaa agagctgaac cacatgctga cggacacagg gaaccgaaag
      241 gcagctgaca agctcatcca gaacctggat gccaaccatg acgggcgcat ctgctttgat
      301 gaatactgga ccatgattgg tggcatcacc agccccatgg ccaacctcat ccgtgagcag
      361 gagtgccagc aggagtgcca gcaggagagc cagcaggaga gccagcagga gagccagcag
      421 gagcagcagg gcagcagcta gaggcccctc tcaggaccct tttcatgtcc tgacccatgt
      481 cctgccagtg ttcttcccat gcttttgact ctttcttccc ttctccctcc agacctgttc
      541 ctatcctagc tgaacagcac aaggtgggcg gggggctatc aaggcctctt tgtgagcatc
      601 tcactgtggt agtgcttccc tgagcattca gtccctggag ccggtaggcc ctgggggggg
      661 tcccctttgt gaaatatcga tgctgtttgg gggcccccaa gacttttccc acttgtcgag
      721 tctgtgtgct cttgcagtgt ctgatgctcc tgtctgattc ttgcctgatt ctgagtttgt
      781 cctgacctct agaggtcagc ttgctgcttg aggtctccca gcttctggct gtggcagctg
      841 tgttggtagc agtaccagaa ttagcctctt ctcttccttc caaactcata gctgggtaga
      901 gaggcattcc caggggctcc tgcccagctg tctctgtctg ggaatgacct aacctgggtt
      961 gagccccctc tctgctcttc caccgaaata aatgctggat ttggagtttg taaaaaaaaa
     1021 aaaaaaaaaa aaaaaa
//
