LOCUS       NM_001007636             601 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus S100 calcium binding protein A1 (S100a1), mRNA.
ACCESSION   NM_001007636 XM_006232603 XM_215606
VERSION     NM_001007636.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Obaid,A.A., Almasmoum,H., Almaimani,R.A., El-Boshy,M., Aslam,A.,
            Idris,S., Ghaith,M.M., El-Readi,M.Z., Ahmad,J., Farrash,W.F.,
            Mujalli,A., Eid,S.Y., Elzubier,M.E. and Refaat,B.
  TITLE     Vitamin D and calcium co-therapy mitigates pre-established cadmium
            nephropathy by regulating renal calcium homeostatic molecules and
            improving anti-oxidative and anti-inflammatory activities in rat
  JOURNAL   J Trace Elem Med Biol 79, 127221 (2023)
   PUBMED   37244046
REFERENCE   2  (bases 1 to 601)
  AUTHORS   Yachie,N., Petsalaki,E., Mellor,J.C., Weile,J., Jacob,Y., Verby,M.,
            Ozturk,S.B., Li,S., Cote,A.G., Mosca,R., Knapp,J.J., Ko,M., Yu,A.,
            Gebbia,M., Sahni,N., Yi,S., Tyagi,T., Sheykhkarimli,D., Roth,J.F.,
            Wong,C., Musa,L., Snider,J., Liu,Y.C., Yu,H., Braun,P.,
            Stagljar,I., Hao,T., Calderwood,M.A., Pelletier,L., Aloy,P.,
            Hill,D.E., Vidal,M. and Roth,F.P.
  TITLE     Pooled-matrix protein interaction screens using Barcode Fusion
            Genetics
  JOURNAL   Mol Syst Biol 12 (4), 863 (2016)
   PUBMED   27107012
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 601)
  AUTHORS   Sen,A., Ren,S., Lerchenmuller,C., Sun,J., Weiss,N., Most,P. and
            Peppel,K.
  TITLE     MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction
            by targeting S100A1
  JOURNAL   PLoS One 8 (11), e78684 (2013)
   PUBMED   24244340
  REMARK    Erratum:[PLoS One. 2013;8(12).
            doi:10.1371/annotation/53080a85-89cc-4a84-8fd9-0eb0c19cc05d]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 601)
  AUTHORS   Bi,H., Yang,Y., Huang,J., Li,Y., Ma,C. and Cong,B.
  TITLE     Immunohistochemical detection of S100A1 in the postmortem diagnosis
            of acute myocardial infarction
  JOURNAL   Diagn Pathol 8, 84 (2013)
   PUBMED   23683996
  REMARK    GeneRIF: depletion of S100A1 was observed in ischemic
            cardiomyocytes, and S100A1 plasma concentration was also
            significantly higher than that of the sham-operated group
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 601)
  AUTHORS   Chen,S., Lu,F.F., Seeman,P. and Liu,F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   6  (bases 1 to 601)
  AUTHORS   Deloulme,J.C., Assard,N., Mbele,G.O., Mangin,C., Kuwano,R. and
            Baudier,J.
  TITLE     S100A6 and S100A11 are specific targets of the calcium- and
            zinc-binding S100B protein in vivo
  JOURNAL   J Biol Chem 275 (45), 35302-35310 (2000)
   PUBMED   10913138
REFERENCE   7  (bases 1 to 601)
  AUTHORS   Kiewitz,R., Acklin,C., Minder,E., Huber,P.R., Schafer,B.W. and
            Heizmann,C.W.
  TITLE     S100A1, a new marker for acute myocardial ischemia
  JOURNAL   Biochem Biophys Res Commun 274 (3), 865-871 (2000)
   PUBMED   10924368
REFERENCE   8  (bases 1 to 601)
  AUTHORS   Heierhorst,J., Mitchelhill,K.I., Mann,R.J., Tiganis,T.,
            Czernik,A.J., Greengard,P. and Kemp,B.E.
  TITLE     Synapsins as major neuronal Ca2+/S100A1-interacting proteins
  JOURNAL   Biochem J 344 Pt 2 (Pt 2), 577-583 (1999)
   PUBMED   10567243
REFERENCE   9  (bases 1 to 601)
  AUTHORS   Song,W. and Zimmer,D.B.
  TITLE     Expression of the rat S100A1 gene in neurons, glia, and skeletal
            muscle
  JOURNAL   Brain Res 721 (1-2), 204-216 (1996)
   PUBMED   8793102
REFERENCE   10 (bases 1 to 601)
  AUTHORS   Zimmer,D.B., Song,W. and Zimmer,W.E.
  TITLE     Isolation of a rat S100 alpha cDNA and distribution of its mRNA in
            rat tissues
  JOURNAL   Brain Res Bull 27 (2), 157-162 (1991)
   PUBMED   1742602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Apr 13, 2016 this sequence version replaced
            XM_006232603.2, NM_001007636.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG378038.1, BI295946.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840107, SAMN12840108
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               JAXUCZ010000002.1  178296206-178296346 c
            142-295             JAXUCZ010000002.1  178294077-178294230 c
            296-601             JAXUCZ010000002.1  178291503-178291808 c
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..601
                     /gene="S100a1"
                     /note="S100 calcium binding protein A1"
                     /db_xref="GeneID:295214"
                     /db_xref="RGD:3614"
     exon            1..141
                     /gene="S100a1"
                     /inference="alignment:Splign:2.1.0"
     exon            142..295
                     /gene="S100a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..439
                     /gene="S100a1"
                     /note="S-100 protein alpha chain; S-100 protein subunit
                     alpha"
                     /codon_start=1
                     /product="protein S100-A1"
                     /protein_id="NP_001007637.1"
                     /db_xref="GeneID:295214"
                     /db_xref="RGD:3614"
                     /translation="MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKDLLQTELSS
                     FLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTVACNNFFWENS"
     exon            296..601
                     /gene="S100a1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcgggtgtc gtttgtgaag gggtggagcc gtcgggagga gggtcggcag taaagacagg
       61 tctccccaca ctgctccggg gcaacatttg cagcgcgccc ttctgtcaag aacctgctcc
      121 gacgtcaggc cgaggccaac cgtgtgctgc tgaaatgggc tctgagctgg agaccgccat
      181 ggagaccctc atcaatgtgt tccatgccca ctcgggcaag gaaggggaca aatataagct
      241 gagcaagaag gagctgaaag acctgctaca aactgaactc tccagcttcc tggatgtcca
      301 gaaggatgca gatgctgtgg acaagatcat gaaggaactg gatgagaatg gagatgggga
      361 agtggacttc caggagtttg ttgtgctggt ggctgctctc acagtggctt gtaacaactt
      421 cttctgggag aacagttgag cacagtctca gtaggcagcg ccctccctct ttgctcctca
      481 tcccacctgt atctccctat gtacccatcc ttgcccaggc tcaacatgca ccaaaggcgc
      541 aacagtagca gtccagatct gccactagtt ttaataaagc ttctctctca cgaactgtca
      601 a
//
