LOCUS       NM_001025405            1857 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RuvB-like AAA ATPase 2 (Ruvbl2), mRNA.
ACCESSION   NM_001025405
VERSION     NM_001025405.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Mir,R.A., Bele,A., Mirza,S., Srivastava,S., Olou,A.A., Ammons,S.A.,
            Kim,J.H., Gurumurthy,C.B., Qiu,F., Band,H. and Band,V.
  TITLE     A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex
            Component RUVBL1 Is Required for the Functional Role of ECD in Cell
            Cycle Progression
  JOURNAL   Mol Cell Biol 36 (6), 886-899 (2015)
   PUBMED   26711270
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1857)
  AUTHORS   Freund,A., Zhong,F.L., Venteicher,A.S., Meng,Z., Veenstra,T.D.,
            Frydman,J. and Artandi,S.E.
  TITLE     Proteostatic control of telomerase function through TRiC-mediated
            folding of TCAB1
  JOURNAL   Cell 159 (6), 1389-1403 (2014)
   PUBMED   25467444
REFERENCE   3  (bases 1 to 1857)
  AUTHORS   Obri,A., Ouararhni,K., Papin,C., Diebold,M.L., Padmanabhan,K.,
            Marek,M., Stoll,I., Roy,L., Reilly,P.T., Mak,T.W., Dimitrov,S.,
            Romier,C. and Hamiche,A.
  TITLE     ANP32E is a histone chaperone that removes H2A.Z from chromatin
  JOURNAL   Nature 505 (7485), 648-653 (2014)
   PUBMED   24463511
REFERENCE   4  (bases 1 to 1857)
  AUTHORS   Dalvai,M., Fleury,L., Bellucci,L., Kocanova,S. and Bystricky,K.
  TITLE     TIP48/Reptin and H2A.Z requirement for initiating chromatin
            remodeling in estrogen-activated transcription
  JOURNAL   PLoS Genet 9 (4), e1003387 (2013)
   PUBMED   23637611
REFERENCE   5  (bases 1 to 1857)
  AUTHORS   Petukhov,M., Dagkessamanskaja,A., Bommer,M., Barrett,T.,
            Tsaneva,I., Yakimov,A., Queval,R., Shvetsov,A., Khodorkovskiy,M.,
            Kas,E. and Grigoriev,M.
  TITLE     Large-scale conformational flexibility determines the properties of
            AAA+ TIP49 ATPases
  JOURNAL   Structure 20 (8), 1321-1331 (2012)
   PUBMED   22748767
REFERENCE   6  (bases 1 to 1857)
  AUTHORS   Dou,Y., Milne,T.A., Tackett,A.J., Smith,E.R., Fukuda,A.,
            Wysocka,J., Allis,C.D., Chait,B.T., Hess,J.L. and Roeder,R.G.
  TITLE     Physical association and coordinate function of the H3 K4
            methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
  JOURNAL   Cell 121 (6), 873-885 (2005)
   PUBMED   15960975
REFERENCE   7  (bases 1 to 1857)
  AUTHORS   Doyon,Y., Selleck,W., Lane,W.S., Tan,S. and Cote,J.
  TITLE     Structural and functional conservation of the NuA4 histone
            acetyltransferase complex from yeast to humans
  JOURNAL   Mol Cell Biol 24 (5), 1884-1896 (2004)
   PUBMED   14966270
REFERENCE   8  (bases 1 to 1857)
  AUTHORS   Bauer,A., Chauvet,S., Huber,O., Usseglio,F., Rothbacher,U.,
            Aragnol,D., Kemler,R. and Pradel,J.
  TITLE     Pontin52 and reptin52 function as antagonistic regulators of
            beta-catenin signalling activity
  JOURNAL   EMBO J 19 (22), 6121-6130 (2000)
   PUBMED   11080158
REFERENCE   9  (bases 1 to 1857)
  AUTHORS   Ikura,T., Ogryzko,V.V., Grigoriev,M., Groisman,R., Wang,J.,
            Horikoshi,M., Scully,R., Qin,J. and Nakatani,Y.
  TITLE     Involvement of the TIP60 histone acetylase complex in DNA repair
            and apoptosis
  JOURNAL   Cell 102 (4), 463-473 (2000)
   PUBMED   10966108
REFERENCE   10 (bases 1 to 1857)
  AUTHORS   Salzer,U., Kubicek,M. and Prohaska,R.
  TITLE     Isolation, molecular characterization, and tissue-specific
            expression of ECP-51 and ECP-54 (TIP49), two homologous,
            interacting erythroid cytosolic proteins
  JOURNAL   Biochim Biophys Acta 1446 (3), 365-370 (1999)
   PUBMED   10524211
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 22, 2021 this sequence version replaced NM_001025405.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098042.1, SRR26643288.2383.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-393               JAXUCZ010000001.1  105051328-105051720 c
            394-448             JAXUCZ010000001.1  105048327-105048381 c
            449-504             JAXUCZ010000001.1  105047046-105047101 c
            505-646             JAXUCZ010000001.1  105046616-105046757 c
            647-776             JAXUCZ010000001.1  105045632-105045761 c
            777-843             JAXUCZ010000001.1  105045463-105045529 c
            844-950             JAXUCZ010000001.1  105041827-105041933 c
            951-1044            JAXUCZ010000001.1  105041657-105041750 c
            1045-1168           JAXUCZ010000001.1  105041393-105041516 c
            1169-1263           JAXUCZ010000001.1  105040972-105041066 c
            1264-1382           JAXUCZ010000001.1  105040769-105040887 c
            1383-1502           JAXUCZ010000001.1  105039273-105039392 c
            1503-1632           JAXUCZ010000001.1  105038979-105039108 c
            1633-1747           JAXUCZ010000001.1  105038684-105038798 c
            1748-1857           JAXUCZ010000001.1  105038487-105038596 c
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1857
                     /gene="Ruvbl2"
                     /note="RuvB-like AAA ATPase 2"
                     /db_xref="GeneID:292907"
                     /db_xref="RGD:1306509"
     exon            1..393
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..1773
                     /gene="Ruvbl2"
                     /EC_number="3.6.4.12"
                     /note="RuvB-like protein 2"
                     /codon_start=1
                     /product="ruvB-like 2"
                     /protein_id="NP_001020576.2"
                     /db_xref="GeneID:292907"
                     /db_xref="RGD:1306509"
                     /translation="MATVAATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQ
                     GMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTA
                     IAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGK
                     LTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAM
                     GSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQI
                     NAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITR
                     IRGTSYQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTR
                     IGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAF
                     LFNELKGETMDTS"
     exon            394..448
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            449..504
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            505..646
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            647..776
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            777..843
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            844..950
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1044
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1168
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1263
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1382
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1502
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1632
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1747
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1857
                     /gene="Ruvbl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatctcagct gtagacccca atttggtgag gaaggttgga cagagaggaa agggatcgtg
       61 gaggacgtgt ggttgctaca aagtgtgttc agaattttgc aatcggactt agcggttgcg
      121 gggcggaggg gaaggaaggg ggaggacgct aggtaacggg aggaggagca ggagacgtca
      181 cgaacccacc ctggattcag aacacccgct ttccaattta gcctctcggg ttgggcgcgg
      241 tctagtgtac gccccccagg acagttttac atagtttatg aaccatagag atgactggat
      301 gaccgggagc ctagagagca cgaaggccgc gctcctagcc catttccgtt tccgctgagg
      361 cattggcggt tggtgtgcat catggcaacc gtggcagcca ctactaaagt ccctgagatc
      421 cgagatgtga caagaatcga gcgaatcggt gctcactccc acatccgggg cctgggactg
      481 gatgatgccc tggagccaag acaggcttcc cagggcatgg tgggacagct agctgcccgg
      541 cgtgcagctg gcgtggtgct ggagatgatc cgagaaggga agattgcggg gcgggctgtc
      601 cttattgctg gccagccagg cacagggaag acagccatcg ccatgggcat ggcccaggca
      661 ttgggccccg acacaccgtt cacagccatc gcaggcagtg agatcttttc tctggagatg
      721 agcaagaccg aggctctaac acaagccttc cgccgttcca ttggtgtccg tatcaaggag
      781 gagacagaga tcattgaagg tgaggtggtg gagatccaga ttgatcggcc agccacaggc
      841 acgggatcca aggtgggcaa actgactctc aagaccacgg agatggagac catctacgat
      901 ctgggtacca agatgatcga gtccctgacc aaggacaagg tccaggccgg ggacgtgatc
      961 accatcgaca aggccactgg caagatttcc aagctgggcc gctctttcac acgtgcccga
     1021 gactatgatg ccatgggctc ccagaccaag tttgtgcagt gcccagacgg agagctgcaa
     1081 aaacgcaagg aggtggtgca caccgtgtcc ctccatgaga ttgacgtcat caactcccgc
     1141 actcagggct tcttggctct cttctcagga gacacagggg agatcaagtc agaagtccga
     1201 gaacagatca atgccaaggt ggcagagtgg agggaggagg gcaaagcgga gatcatccct
     1261 ggggtgctgt tcatcgatga ggtccacatg ctggacattg agagtttctc tttcctaaac
     1321 cgggccctgg agagtgacat ggcgcctgtt cttatcatgg ccaccaaccg aggcatcacc
     1381 cggatccgag gcaccagcta ccaaagtccc cacggcatcc ccattgacct gctagaccgg
     1441 ctgctcattg tgtcaacatc gccctacagt gagaaggaca ccaaacagat cctacgtatc
     1501 cgctgtgagg aggaagatgt ggagatgagt gaggacgcct acacagtgct gacccgcatt
     1561 gggctcgaga cctccctgcg ctacgccatc cagctcatca cagcggccag cctggtgtgc
     1621 cggaaacgaa agggcacgga ggtgcaggtg gacgacatca agcgcgtata ctccctcttc
     1681 ctggatgaat cccgctccac acagtacatg aaggaatacc aggacgcctt cctcttcaat
     1741 gagctcaaag gtgaaacaat ggacacctcc tgagctgaca ctgcacccca acccttccca
     1801 gcctgttttc tacaagttct aacactgtga ctttgtataa aattattgaa aactgga
//
