LOCUS       NM_147177               1587 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus RuvB-like AAA ATPase 1 (Ruvbl1), mRNA.
ACCESSION   NM_147177
VERSION     NM_147177.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1587)
  AUTHORS   Mir,R.A., Bele,A., Mirza,S., Srivastava,S., Olou,A.A., Ammons,S.A.,
            Kim,J.H., Gurumurthy,C.B., Qiu,F., Band,H. and Band,V.
  TITLE     A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex
            Component RUVBL1 Is Required for the Functional Role of ECD in Cell
            Cycle Progression
  JOURNAL   Mol Cell Biol 36 (6), 886-899 (2015)
   PUBMED   26711270
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1587)
  AUTHORS   Freund,A., Zhong,F.L., Venteicher,A.S., Meng,Z., Veenstra,T.D.,
            Frydman,J. and Artandi,S.E.
  TITLE     Proteostatic control of telomerase function through TRiC-mediated
            folding of TCAB1
  JOURNAL   Cell 159 (6), 1389-1403 (2014)
   PUBMED   25467444
REFERENCE   3  (bases 1 to 1587)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1587)
  AUTHORS   Ivatt,R.M., Sanchez-Martinez,A., Godena,V.K., Brown,S., Ziviani,E.
            and Whitworth,A.J.
  TITLE     Genome-wide RNAi screen identifies the Parkinson disease GWAS risk
            locus SREBF1 as a regulator of mitophagy
  JOURNAL   Proc Natl Acad Sci U S A 111 (23), 8494-8499 (2014)
   PUBMED   24912190
REFERENCE   5  (bases 1 to 1587)
  AUTHORS   Obri,A., Ouararhni,K., Papin,C., Diebold,M.L., Padmanabhan,K.,
            Marek,M., Stoll,I., Roy,L., Reilly,P.T., Mak,T.W., Dimitrov,S.,
            Romier,C. and Hamiche,A.
  TITLE     ANP32E is a histone chaperone that removes H2A.Z from chromatin
  JOURNAL   Nature 505 (7485), 648-653 (2014)
   PUBMED   24463511
REFERENCE   6  (bases 1 to 1587)
  AUTHORS   Makino,Y., Kanemaki,M., Kurokawa,Y., Koji,T. and Tamura,Ta.
  TITLE     A rat RuvB-like protein, TIP49a, is a germ cell-enriched novel DNA
            helicase
  JOURNAL   J Biol Chem 274 (22), 15329-15335 (1999)
   PUBMED   10336418
REFERENCE   7  (bases 1 to 1587)
  AUTHORS   Kikuchi,N., Gohshi,T., Kawahire,S., Tachibana,T., Yoneda,Y.,
            Isobe,T., Lim,C.R., Kohno,K., Ichimura,T., Omata,S. and Horigome,T.
  TITLE     Molecular shape and ATP binding activity of rat p50, a putative
            mammalian homologue of RuvB DNA helicase
  JOURNAL   J Biochem 125 (3), 487-494 (1999)
   PUBMED   10050036
REFERENCE   8  (bases 1 to 1587)
  AUTHORS   Kurokawa,Y., Kanemaki,M., Makino,Y. and Tamura,T.A.
  TITLE     A notable example of an evolutionary conserved gene: studies on a
            putative DNA helicase TIP49
  JOURNAL   DNA Seq 10 (1), 37-42 (1999)
   PUBMED   10565543
REFERENCE   9  (bases 1 to 1587)
  AUTHORS   Bauer,A., Huber,O. and Kemler,R.
  TITLE     Pontin52, an interaction partner of beta-catenin, binds to the TATA
            box binding protein
  JOURNAL   Proc Natl Acad Sci U S A 95 (25), 14787-14792 (1998)
   PUBMED   9843967
REFERENCE   10 (bases 1 to 1587)
  AUTHORS   Kanemaki,M., Makino,Y., Yoshida,T., Kishimoto,T., Koga,A.,
            Yamamoto,K., Yamamoto,M., Moncollin,V., Egly,J.M., Muramatsu,M. and
            Tamura,T.
  TITLE     Molecular cloning of a rat 49-kDa TBP-interacting protein (TIP49)
            that is highly homologous to the bacterial RuvB
  JOURNAL   Biochem Biophys Res Commun 235 (1), 64-68 (1997)
   PUBMED   9196036
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB002406.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB002406.1, BC086531.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1587
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1587
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /note="RuvB-like AAA ATPase 1"
                     /db_xref="GeneID:65137"
                     /db_xref="RGD:68373"
     exon            1..171
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..1401
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /EC_number="3.6.4.12"
                     /note="RuvB-like protein 1; pontin 52; DNA helicase p50;
                     49 kDa TBP-interacting protein; 49 kDa TATA box-binding
                     protein-interacting protein"
                     /codon_start=1
                     /product="ruvB-like 1"
                     /protein_id="NP_671706.1"
                     /db_xref="GeneID:65137"
                     /db_xref="RGD:68373"
                     /translation="MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQEN
                     AREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVY
                     STEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIG
                     LKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAE
                     EYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLR
                     GEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRG
                     NCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALN
                     HLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQ
                     QDKYMK"
     exon            172..258
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            259..391
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            392..543
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            544..633
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            634..783
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            784..847
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            848..1046
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1149
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1241
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1581
                     /gene="Ruvbl1"
                     /gene_synonym="NMP238; Pontin52; Tip49a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcaggttgt ggctgcacac actcgtcaaa atgaagattg aggaggtgaa gagcaccacg
       61 aagacgcaac gcattgcctc ccacagccac gtgaaggggc tggggctgga tgagagcggc
      121 ctggccaagc aggcggcttc ggggctcgtg ggccaggaga acgcgagaga ggcatgtggt
      181 gtcatagtcg aattaatcaa aagcaagaaa atggctggaa gagctgtctt gttggcaggg
      241 cctcctggaa ctggcaagac agccttggcc ctggctattg ctcaggaact gggcagtaaa
      301 gtccctttct gcccgatggt gggtagtgaa gtatactcaa ctgagatcaa gaagacagag
      361 gtgctgatgg agaacttccg aagggctatt gggctgcgga taaaggagac taaggaggtt
      421 tatgaagggg aggtgacaga gctcactccc tgtgagacag agaaccccat gggtgggtat
      481 ggcaaaacta tcagccacgt gatcataggg ctcaagactg ccaaaggaac caaacagctg
      541 aagctggacc ccagtatttt tgaaagtttg cagaaagaac gagtagaggc tggagatgtg
      601 atttacattg aagcaaacag tggagctgtg aagaggcaag gcaggtgtga cacctatgcc
      661 acagagtttg accttgaggc tgaagagtat gtccctttgc caaagggaga tgtgcacaag
      721 aagaaggaaa tcatacagga tgtgaccttg cacgacttgg acgtggccaa tgcgcggcct
      781 cagggtgggc aagatattct gtctatgatg ggccagttga tgaagccaaa aaagacagag
      841 atcacagata aacttcgagg ggagatcaac aaggtggtga acaaatacat tgaccagggc
      901 gttgcagagc tggtccctgg agtgctcttt gttgacgagg tccacatgct ggatatcgag
      961 tgctttacct acctgcaccg agccctggag tcctccatcg cccccattgt catctttgca
     1021 tccaaccgag gcaactgtgt catcaggggc accgaggaca tcacttctcc acacggcatc
     1081 ccgttggacc tgctggaccg ggtgatgatc atcaggacca tgctgtatac gccacaggag
     1141 atgaagcaga tcattaagat ccgagcccag acggaaggca tcaacatcag tgaggaggcc
     1201 ctaaaccacc tcggggagat tggcaccaag accacgctga ggtattcagt gcagctgctg
     1261 acccctgcca acctgctggc caagatcaac gggaaggaca gcattgagaa ggagcacgtg
     1321 gaggagatca gcgagctctt ctatgacgcc aagtcctccg ccaagattct ggccgaccag
     1381 caggacaagt acatgaagta acgtagggtt tggaggtgca cccagaggac agaccccaca
     1441 ccgaggacag ggtcttgcgt tgagcatgct ttgcagtgtt acagtttgtt tgtaaattat
     1501 caaacctcca aggttgtttg gaaggaaccc tttcccacct agcttgtttt tctaataaaa
     1561 ctgaatctta ttttgatgat aaaaaaa
//
