LOCUS       XM_039111000            5980 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RUN and SH3 domain containing 2
            (Rusc2), transcript variant X3, mRNA.
ACCESSION   XM_039111000
VERSION     XM_039111000.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039111000.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5980
                     /gene="Rusc2"
                     /note="RUN and SH3 domain containing 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 14 ESTs, 8 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     101 samples with support for all annotated introns"
                     /db_xref="GeneID:684259"
                     /db_xref="RGD:1592688"
     CDS             1433..5980
                     /gene="Rusc2"
                     /codon_start=1
                     /product="AP-4 complex accessory subunit RUSC2 isoform X1"
                     /protein_id="XP_038966928.1"
                     /db_xref="GeneID:684259"
                     /db_xref="RGD:1592688"
                     /translation="MPLLEISRMDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGG
                     GRGTRANPFCPPELGLTQPDQDLGQADSLLYTSLHSAPGAPTRSSDGVKSRSRDGRGP
                     GAPKRHNPFLVQEGVGETGLGDLHDGSTGDGATQQSFHLHSTSQPFHLSSFQLPPSGP
                     GQGRPWGAARSRPGVVEGQEQDPATTLGTQCSNSHCCRPEPEAETMELDECGGHGGSG
                     SGGGNNDISGFSFEQEWKLSSDESPRHPGRSGSGAQHCHCSSTSSQSEAADQSMGYVS
                     DSSCNSSDGVLVTFSTLYNKMHGSPRANLNSVPQSCSDSSFCSHADPGAFYLDLQPSP
                     AESRMSCESHHPESGDREEGCGCPHASSPELDANCNAYRPHCEPCPAVADLTACFQSQ
                     ARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGSDPDPSQPSE
                     YYLFQKPEEQEAVGSSTEAATTMGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLERS
                     PAVRLGSLERMLSCPVRLSEGPGALAGPASPPRRVTSFAELAKGRKKAAGSGSPPLRV
                     SIGESSQEFSPIQEAQQDRAGPLDEGTRCSHSLPSMPLGPSLDLLGPEPWSTQVCQDP
                     QSSEMLLPSLRASGQGLLAQPMDPVPALLGSPANSHTQRDARARADGGGTESRPVLRY
                     SKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRAQQPAPLVISTAQG
                     SAPAPSGEPQAFPSQTTGRGARNAGPEPETSRPSPLGSYSPVRSAGPFGSSTDSSAST
                     SCSPPPEQATASESLRPWSHPCPPPVRPATSQQPRKEDQKIPTLAEYRLHGTGSLPPL
                     GSWRSGFTRTESLARGGGEGSMASRPNNVNHLSPQALKWREYRRKNPLGPPGVSGSLD
                     RRPQEARLAHRNPIFEFPGSFGTTNHLNCRLNGQIAKPLSLTCPDLQDPFSLTEKPPA
                     EFCLSPDGNSEAVSIDILQKRGLVKAVNTAVDLIVAHFGTSRDPGVKAKLGNSSVSPN
                     VGHLVLKYLCPAVQAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLY
                     NKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYDHEDIIQTHYQPWGFLRAAHT
                     VCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQNGRQQRQHKELLRVSQDLLLSAHST
                     LQLARARGQEGPGDVDRAAPGERVKGVGASEGGEEDEDDSEEVAVVPGSSDHGKWARG
                     GQAGWWYQLMQSSQVYIEGTAEGSRFPRSSSSSSGGGEKKKGAGGGGPSQTPPPPPRE
                     GVVEGAEACPAPEEALGQERGWPFWMGSPPDSVLAELRRSREREGPVAPPTENEGTPE
                     PSPGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSVFQLVAQTMGARREPEPRENL
                     QESHPPAVPSKPPCEVQALCHHLATGPGQLSFHKGDILRVLGPAGGDWLCCSRGPDTG
                     LVPLAYVTLTPTPSSPGNSQN"
ORIGIN      
        1 aaagcctgcc agtgtagatc tgatggacac aggatggtgg acttagcctc agtgcagggg
       61 ggaaagtgca gagtccatct cccttgactc tgttttggct tttgaaacag tgtctctcag
      121 tccagacagg cctggaagct gccgtgtagc tgaggccgcc tgcctctctg aagcgctagg
      181 gttgcaagtg tacatcccat gccagtttat tcctttggct gcaagacggt ttgtctataa
      241 atgccttaga cctaaaggct ttagcttttt ctggaaacag ggaaaagaaa agaaacagcc
      301 acactagtca tctgccacag aataacagtg gtgacacatt gttgagcact taggtgtgat
      361 gtgcgctcaa gcctccgagg gaatagcaca gcagtttaca gcctgctgag ggttaggtca
      421 actgacttcc cagagctcca tagctggcaa gccctgtgtc agattggaac ctaggaccat
      481 cgttacagca actcgtaaca cattacagaa acttacccca tgaaccctca ggacagagcc
      541 cgagacgtgg acgaaaacaa aagttaggct aaccttggac ttgtaactaa agcagatacc
      601 attgtcgtgt ctttgctgat actacaaagg tcgtccccag tgctctcccc aggaaaggag
      661 agccggactc tgccatctaa actctactgg aaaaataagg cacacccagg aaagtcccag
      721 agcccatgtc cccacggctg agaaaatggc cagactggaa cctggttccc tagggcggtg
      781 agcctgagat gacagtccca ctgaggcggg ggtggggcgt gggggaggtg tgcttggaga
      841 tttccttgaa aggcatcgag gcttccctct gctctctctc ctaactcccc aaccctggtc
      901 ccacaaatgg tgtttgtaat tcaatctaga ttcctctcat agccccctct ctgcatatgc
      961 gcccttttat ttacagctct ggacaaactg attggctagc agtttggcac cctgcaggct
     1021 tcagtccact gtctgggagg aggggcgggg agcagagagc actgtgactt ggcttcccag
     1081 agcgcaggag ccaagaggca ccgctgaagt aatagcaagg tgttgaccac attggacagc
     1141 gccaggagcc tcatttgatc cggctgcctt aactctccta caaattagtc ctttaaaact
     1201 ttctccaagc aaaggaggcc acaccaggct tcagcacccg cctcttcctg tctctagcct
     1261 cggtggtttc ttgcctcctg catctggcat tgggagactt taccctgagg ccctgttgac
     1321 tgctgtttac tgcacccctc gtctgaagag ctcggtctgt caaggtgcca acctttcctg
     1381 atgaaatgtg ttctgcccca ctgggctcca aaggcagtgt ctggtgctgt tgatgccctt
     1441 gttggaaatt tccagaatgg atagcccccc taagctgact ggagagaccc tcatcgtcca
     1501 ccatatcccc ttagtgcact gccaagtccc agacaggcag tgctgtgggg gcgccggtgg
     1561 aggtggcagg ggaacaagag ccaatccctt ctgccccccg gagctgggcc ttactcagcc
     1621 cgaccaagac ctaggacaag ctgactccct cttgtacacc agcctgcact cggccccagg
     1681 ggcaccgaca cggtcttcag acggcgtcaa gagtaggagt cgggatggac gaggccctgg
     1741 agctcccaaa cggcacaatc ccttcttggt gcaggaaggt gtgggtgaga caggactcgg
     1801 tgacctgcac gatggcagca ctggtgacgg tgccacccag cagtcgttcc acctgcacag
     1861 caccagccag cccttccatc tgtcttcttt ccagctgcca ccatctggcc ccggacaggg
     1921 caggccgtgg ggcgcagcac gcagtcggcc tggagtggtg gaggggcagg aacaggaccc
     1981 agcgaccacc ttggggaccc agtgcagcaa tagccactgc tgccgaccag agccggaggc
     2041 tgagacgatg gagctggacg agtgtggggg acacggggga agtggcagtg gagggggcaa
     2101 caatgacatc tctggctttt cctttgaaca agagtggaag ctcagttccg acgaatcccc
     2161 gagacaccct gggcgttccg gttcgggagc tcagcactgc cactgcagta gcacgtccag
     2221 tcagtccgag gcagctgacc agtccatggg ctacgtcagc gactcctcct gtaacagctc
     2281 cgacggggtg ctagtcacgt tcagcaccct ctacaacaag atgcacggca gcccccgtgc
     2341 caacctcaac tccgtccctc agtcctgcag cgactcctcc ttctgcagcc acgcagaccc
     2401 tggagccttt tacctggacc tgcagccctc cccagccgag tcaagaatgt cttgtgagtc
     2461 ccaccacccc gagagtgggg acagggaaga gggctgcggg tgtcctcatg cctcgtcccc
     2521 tgagctcgat gccaactgca acgcctaccg cccacactgt gagccctgcc cagccgtggc
     2581 tgacctcaca gcctgcttcc agagccaggc ccgccttgta gtggccacac aaaattacta
     2641 taaacttgtc acctgtgacc tgtcctccca gtcctccccg agccccgctg gctcgtccat
     2701 caccagttgc tcagaagaac ataccaagat aagtcctcca ccaggccccg gctcagaccc
     2761 ggaccccagc cagccctctg agtattacct cttccagaag ccagaggaac aagaagcagt
     2821 gggttcctca acagaagcag cgaccaccat gggccccact gtccttgaag ggcaagtgta
     2881 cacaaatact tcccccccca acctcagcac tggccggcaa cgctctcgga gctatgatcg
     2941 aagcctagag cgcagccccg ccgttcgcct gggctcactg gagcgcatgc taagttgtcc
     3001 agtgcgctta agtgagggcc ccggggccct ggctgggcct gcttccccgc ccaggagggt
     3061 tacctcattt gctgagttgg ccaaaggccg gaagaaagct gcaggctctg gctccccacc
     3121 acttcgggtg agcatcggag agtcttccca ggagttctcg cccatccaag aagcccaaca
     3181 agatagggca ggcccactcg atgagggcac ccgatgtagc catagcctgc cgtccatgcc
     3241 cttggggcca agcctggacc tccttggccc agaaccctgg tccacccagg tttgtcagga
     3301 cccccagtcc agtgagatgc tacttcctag cctcagagct tctgggcagg gactcttggc
     3361 gcagccgatg gatcctgtgc ctgctctcct agggagccca gccaacagcc atacccagag
     3421 ggatgcaaga gctagagctg acgggggtgg cactgaaagc cgacccgtcc ttcgctacag
     3481 caaggaacag aggccgacca ccctacctat ccagccgttc gtgttccagc atcacttccc
     3541 caagcagctg gccaaggccc gggccctcca cagcctttcc cagctctaca gcctctcggg
     3601 ctgcagccgc gcacagcagc ctgccccact ggttatctct actgctcaag gctcagcccc
     3661 agctccctca ggagaaccac aggcattccc atcccagact actggccgag gtgccagaaa
     3721 cgctgggcct gagccagaga cctcaaggcc atcacccctg ggaagctact ccccagtccg
     3781 gagtgccggc ccctttgggt ctagcaccga ttcatctgcc tctacctcct gttccccgcc
     3841 tccagagcag gccacagcat cagaaagtct acggccatgg agccacccct gtcctcctcc
     3901 tgtgcggcct gccacctccc agcagccacg gaaggaggac cagaagattc cgaccttggc
     3961 tgagtaccgg cttcatggca caggaagcct gccgcctctg ggctcctgga gatctggctt
     4021 tacccggaca gagagtctgg ctcgaggagg tggcgagggc agcatggcat ccagacccaa
     4081 caatgtcaac cacctatccc cccaggccct caagtggcgg gaatacagga ggaagaaccc
     4141 actagggcct cctggtgtgt cgggaagcct agaccgaagg ccacaggaag ctcggctggc
     4201 ccacaggaac cccatcttcg agttccccgg ttctttcggc acaaccaacc atctgaattg
     4261 ccgtctgaat ggtcagatcg caaagccatt atcattgacc tgccccgacc tgcaggaccc
     4321 cttctcctta actgagaagc ctccagctga gttctgtctg tctccagatg gcaactcgga
     4381 ggccgtttcc attgacatcc ttcagaaaag agggctggtg aaagctgtca acaccgcggt
     4441 ggaccttatt gtggcccatt ttggcacaag ccgggaccct ggcgtcaagg cgaagctggg
     4501 gaacagctct gtgagcccca acgtaggcca cctggttctg aagtacttgt gccctgcggt
     4561 ccaggctgtt ctggaggatg ggctcaaggc cttcgtgctg gatgtgatca tcggccaacg
     4621 taaaaacatg ccttggagtg tggttgaggc ttccacacag ctaggcccat ccaccaaggt
     4681 cttgcatggc ctctacaaca aagtcagcca gttcccagaa ctcaccagtc acactatgcg
     4741 cttcaacgct ttcatcctcg gcctgctcaa catccggtcc ctggagttct ggttcaatca
     4801 cctgtatgac catgaagata tcatccagac ccactaccag ccctggggct tcctgcgggc
     4861 cgcccacacg gtgtgccctg gcctctttga ggagctgctg ctgctgctac agcccttagc
     4921 cctgctgccc ttcagcctgg acttgctgtt ccagcaccgg ctgctgcaaa atgggcggca
     4981 gcagcggcag cacaaggaac tgctgcgagt gtcccaggac ctgctgctgt ccgcacactc
     5041 aacactgcag ttggccaggg cccgaggcca ggagggtcct ggagacgtgg acagggcggc
     5101 tcctggagag cgggtgaagg gggtgggtgc ctcagaaggt ggagaagagg atgaggacga
     5161 ctcggaagag gtggcggtgg tgccgggtag ctcggatcac ggcaagtggg cccgaggggg
     5221 tcaggctggc tggtggtacc agctcatgca gagctcccag gtctacatcg agggcactgc
     5281 tgagggctct agattccctc gcagtagcag cagtagcagc ggcggtggtg agaagaagaa
     5341 aggagctggc ggtggggggc catcccagac tccaccccct ccgcctcggg aaggtgtagt
     5401 agagggggcg gaggcctgcc ctgccccaga ggaggccctt ggccaagaaa ggggctggcc
     5461 tttctggatg gggagccccc ctgactccgt gctagctgag ctgaggcgga gtcgagagag
     5521 ggaagggcct gttgccccac caacggaaaa tgaagggacc ccagagcctt cacctggggg
     5581 catcaagtgg ggacatctct ttggttctcg aaaagctcag cgggaagccc ggcccacaaa
     5641 caggctgcct tcggactggc tgagcctgga caagtctgtg ttccagctgg tagcacagac
     5701 gatgggggcc cgtcgggagc ccgagccccg ggagaacctg caagagtcac accctccagc
     5761 tgtgccctcc aaacctccgt gcgaggtgca ggcgctgtgc caccatctgg ctacaggccc
     5821 tggacaactg agcttccaca aaggagatat cctccgggtg ctgggaccag caggaggaga
     5881 ttggctgtgc tgcagccgtg gccctgacac tggcctggta cctctggcct atgtgacatt
     5941 gaccccaact ccaagttcac ctgggaacag ccaaaactga
//
