LOCUS       NM_001100727            2666 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus RUN and FYVE domain containing 1 (Rufy1), mRNA.
ACCESSION   NM_001100727 XM_001071405 XM_340794
VERSION     NM_001100727.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2666)
  AUTHORS   Yang,J., Kim,O., Wu,J. and Qiu,Y.
  TITLE     Interaction between tyrosine kinase Etk and a RUN domain- and FYVE
            domain-containing protein RUFY1. A possible role of ETK in
            regulation of vesicle trafficking
  JOURNAL   J Biol Chem 277 (33), 30219-30226 (2002)
   PUBMED   11877430
REFERENCE   2  (bases 1 to 2666)
  AUTHORS   Cormont,M., Mari,M., Galmiche,A., Hofman,P. and Le
            Marchand-Brustel,Y.
  TITLE     A FYVE-finger-containing protein, Rabip4, is a Rab4 effector
            involved in early endosomal traffic
  JOURNAL   Proc Natl Acad Sci U S A 98 (4), 1637-1642 (2001)
   PUBMED   11172003
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Oct 25, 2008 this sequence version replaced
            XM_340794.3, XM_001071405.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643291.27536.1,
                                           SRR22399484.848687.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-337               JAXUCZ010000010.1  35251360-35251696   c
            338-511             JAXUCZ010000010.1  35243112-35243285   c
            512-629             JAXUCZ010000010.1  35240455-35240572   c
            630-731             JAXUCZ010000010.1  35239687-35239788   c
            732-855             JAXUCZ010000010.1  35237971-35238094   c
            856-917             JAXUCZ010000010.1  35234558-35234619   c
            918-983             JAXUCZ010000010.1  35232145-35232210   c
            984-1053            JAXUCZ010000010.1  35228625-35228694   c
            1054-1155           JAXUCZ010000010.1  35225925-35226026   c
            1156-1272           JAXUCZ010000010.1  35224467-35224583   c
            1273-1440           JAXUCZ010000010.1  35222967-35223134   c
            1441-1538           JAXUCZ010000010.1  35219966-35220063   c
            1539-1658           JAXUCZ010000010.1  35217099-35217218   c
            1659-1788           JAXUCZ010000010.1  35216396-35216525   c
            1789-1883           JAXUCZ010000010.1  35212940-35213034   c
            1884-1932           JAXUCZ010000010.1  35209843-35209891   c
            1933-2010           JAXUCZ010000010.1  35207812-35207889   c
            2011-2666           JAXUCZ010000010.1  35206801-35207456   c
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..2666
                     /gene="Rufy1"
                     /note="RUN and FYVE domain containing 1"
                     /db_xref="GeneID:360521"
                     /db_xref="RGD:1305099"
     exon            1..337
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..2154
                     /gene="Rufy1"
                     /codon_start=1
                     /product="RUN and FYVE domain-containing protein 1"
                     /protein_id="NP_001094197.1"
                     /db_xref="GeneID:360521"
                     /db_xref="RGD:1305099"
                     /translation="MAARGDCRRAGQDSEPEPKPEPESRPEPGLQAGLESGEEFEIVD
                     RSQLPSPGELRSASRTRAAESWSAPILTLARRATGNLSASCGSALRAAAGLGDGGGGG
                     GERAASKGQMMEERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLK
                     HGLKVKKSFIGQNKSFFGPLELVEKLCPEASDIATSVRNLPELKTAVGRGRAWLYLAL
                     MQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKGEDL
                     DSQVGVIDFSLYLKDVQDLDSGREHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDG
                     LEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETY
                     KQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQD
                     TLVALRQQLEEVKAINLQMFHKVQSAESSLQQKDEAIASFEGKTTQVMSSMKQMEERL
                     QQAERARQGAEERSYKLQQELSGRVSALQLQLSQLRDQCSGLEKELKSEKEQRQTLQR
                     ELQHEKDTSCLLQTELQQVEGLKKELRELQDEKAELRKVCEEQEQALQEMGLHLSQSK
                     LKMEDIKEVNKALKGHTWLKDDEATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNE
                     LALPSYPKPVRVCDSCHTLLLQRCSSTAS"
     exon            338..511
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            512..629
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            630..731
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            732..855
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            856..917
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            918..983
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1053
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1155
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1272
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1440
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1538
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1658
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1788
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1883
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..1932
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..2010
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2666
                     /gene="Rufy1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcacgtgac cggccaacat ggccgcccgc ggagactgcc gccgggcggg gcaggattcg
       61 gagccggagc cgaagccgga gcccgagtcg cggccggagc ctgggctcca agcaggccta
      121 gagtccgggg aagagttcga gatcgtggac cggagccagc tgccaagccc cggcgagctg
      181 cggagcgcgt cgcggactcg agcggccgaa agctggtcgg cgcccatcct gacgctggcg
      241 cgcagagcca ccgggaacct gtcggcgagc tgcggcagcg cgctgcgcgc ggccgcgggg
      301 ctgggagacg gcggcggcgg cggcggggag cgcgcagctt ccaaaggcca gatgatggag
      361 gagcgtgcca acctaatgca catgatgaaa ctcagcatta aggtcttact ccagtctgcc
      421 ctgagcctgg gacgcagcct ggatgcagac catgctccct tacagcagtt ctttgtagtg
      481 atggagcatt gcctcaagca tgggctaaaa gtcaagaaga gtttcattgg ccaaaataaa
      541 tctttctttg gtcctttgga gctggtggaa aaactttgcc ctgaagcatc agatatagct
      601 accagtgtca ggaatcttcc agaactaaag acagccgtgg gaagaggcag agcgtggctt
      661 tatcttgctc tcatgcaaaa gaaactggca gattatctga aagtcctcat agacaacaag
      721 catctcctaa gtgagttcta tgagcctgag gccttaatga tggaggagga aggaatggtg
      781 attgtcggtc tgctggtggg gctcaacgtt ctggacgcca atctctgctt aaagggagaa
      841 gacctggatt ctcaggtcgg agtgattgac ttttccctct atctgaagga cgtgcaggat
      901 cttgacagcg gcagagagca tgaaagaatt accgatgtcc ttgatcagaa aaattacgtg
      961 gaggaactta accggcactt aagctgcaca gttggggatc ttcaaaccaa gatagatggc
     1021 ttggaaaaga cgaactcaaa gcttcaagaa gagctttcag ctgcaacaga ccgaatttgt
     1081 tccctacaag aagaacagca gcagctaaga gaacagaatg aattaattcg agaaagaagc
     1141 gagaagagtg tggagataac aaaacaggac accaaagttg aactggagac ttataagcag
     1201 acccggcagg gcctggatga aatgtacagc gatgtgtgga aacagctgaa ggaggagaag
     1261 aaagtccgac tggaactaga aaaggaactg gagttacaga ttggaatgaa gaccgagatg
     1321 gaaatcgcca tgaagttact ggagaaggac acccatgaga agcaggacac actcgttgcc
     1381 ctccgccagc agctggaaga agtcaaagca attaatttac agatgtttca caaagttcag
     1441 agtgcagaga gcagtttaca gcagaaggat gaagccattg catcttttga aggaaaaacc
     1501 acccaagtga tgtccagcat gaaacaaatg gaggaaaggt tacagcaggc tgagcgggcc
     1561 aggcaagggg cagaagagag gagctacaag ctgcagcagg agctcagcgg gagggtcagt
     1621 gccctgcagc tgcagctgtc ccagctgcgg gaccaatgct caggtctaga gaaagaactg
     1681 aagtcagaaa aagaacaaag acaaactctt cagagagaac tacagcatga gaaagacacc
     1741 tcctgtctgc tgcagacaga gctgcagcaa gtggaaggcc tgaagaagga gcttcgggag
     1801 ctccaagacg agaaggcaga gttgcggaag gtctgtgagg aacaggagca agccctccag
     1861 gaaatgggac tgcaccttag ccagtccaaa ctgaagatgg aggacatcaa ggaagtaaac
     1921 aaggctctga agggccacac atggttgaaa gatgatgagg caacacattg taagcagtgt
     1981 gagaaggact tctccatttc ccggaggaag caccactgcc ggaactgtgg ccacattttc
     2041 tgcaacacct gctctagcaa cgagctggct ctgccctcct accctaagcc agtgcgtgtg
     2101 tgtgacagct gccataccct gctactgcag cgctgctctt ccacagcctc ctgaagccat
     2161 cagccctgcc agcagggacc ttagcctgtt gacctccatc ctcaagagtg gagggagcct
     2221 caggtacagt gccaaacttg ggatctccag agacctgcag ggacccaaga gaatcaaagg
     2281 aaagaatgaa gccttcacca ggccgtcagc ctctgaagag agcgcccagt ggcggctgag
     2341 cactttccat ggcttatgtg gagccggctc ctgtagatac ttcgtgtcct cggttatgtc
     2401 ctggctttgg gacaggtgca aactcacaat tttgctatgc cactttcact cttcggagga
     2461 ttgacctgtt ttgcagcagt ttgctagtac agaatcctct ttcctacccg cgtcccacag
     2521 aaaccttgat ttctgctgtg ctttgaaccg tgtgggtctg tcagcgtgcc ttgtccgctt
     2581 cagcacccag cattggccat catgcccctg gcaactccta ctgttagccc tgcaataaag
     2641 tcctttattt ttcactcttg tacaaa
//
